>XP_030855970.1 low-density lipoprotein receptor-related protein 5-like [Strongylocentrotus purpuratus | PB0003
MYPSNFPDITIPDDFNITNMLVNRNHAVALAVDLEDGLVFYSDVASKAIGMASLRVGSTVRYITGATGSVEGMAVDWLTK
HLYWTDNPRGTIEVSRYDGSYRTTLLKDKVLRPRSIAIDPAKKVMFWTEFGPPTQIERASLDGTGRMEIIGPTQGVGQMS
GLVIDYKEKRLYFADIARGIISSVDYDGGGIRQVISKPNSLFFEVTLYKDYIMWTELGPNQGIFISNKETGEAVRAFPMT
EEVYGITMYADTRQKIIHNPCRSYNGGCQQLCLNSYEQTNGYVCHCSMGYYLADNGRDCHSDLVDHDFLLVTDTYHRGIY
QVDLYSNFKPEALRLNGVKNPIGISFDPVERMVYWTDVEKREVNRASLDGSRQDTIAIENIGQPDGIAVDSISKLVYWSD
LATRSISVSTLDGSDRKTLVTNIAKPRAIVLHPVEGIMFWSDWRSSTVIERSYMDGDMRRVIINTGLRWTNGLAIDFEEN
RLYWCDGGLDVIESSDFSGRDRRVVLNLGDGRHAFGISVIDQSVYWTDWMVKGLLKADKLTGQNNVVLGKRDFTRPNALF
VVTNASLPSGINSCSENNGGCSTLCLPTAIGRSCACADGVDLAQDGLTCVSELDIQCPLDFIYGGVEESCDRSAGSTCSV
ICYSGLVPAVDYVICQNSGSWDIPRSAICREEQCEALDVPNHAIFSGPCNPPYDQGKLCILECEPGYVRTSGKPRRVCAH
GGEWLGTPIVCEEMVEPPPEGECSSELAFQETPEDYSPVQDDLVQQSCTTNSPQADITWYKDGVRLMTGSVNGIYILPSN
DLLIPGFDTHHQGHYACVASFSGRECLRVEVDFAFDPYRHFEAVPANASLDVGDHHLFECQAQSAIDSVTWWKDGSRVHQ
TDQIILISGGSLLIRNLVRQDSGKYTCIVSDQRGNQRGKAYAWLTVADTMNPPTINITEVCGTVTSPEATMFTTPGPRDG
RVVGGQQSLPGSAPYMGRIWHKADRTFVCGATLLNQRWVITAAHCIVLYQLQFRDILLYFGDHDTLTSEDHQVIAEVDQI
IQHEDFDEESFDKDIALIRLKQPFAEFTDYIRPICIPPAWLAKMLLQPDMMGRVTGWGQIAEGGPYPRYLTEVDLPVVKS
KKCKDATTFEVTRYMFCAGYASAEEKKDACQGDSGGPFAMLHENRWYQLGIVSWGEGCARDSKYGYYTKILRLHSWIDRN
ISD

>XP_030837166.1 relaxin receptor 2-like [Strongylocentrotus purpuratus | PB0005
MPPRVFIIGSGSCQWANDLIECDPGFFPCGNSTECVAQQFQCDDIAHCQNAADESGCAIADGWLAHFDYVHPVSVGETKA
LNECALAQYPDGCVCSKLTQLDCSEFNLNEVPPNLPENITRLYLKSNNIVNIGSELLANYSSLVYLNLMGNRIHEIAENS
FRNLRNLKRLFLSENNISRIQTGAFNGLSGLHWLFLNDNKMRTLEPGIFLGLEGLYWLDMRNNEIRDLQEGEALKDLKSL
VWLDFEGNDIRSINARSFAGNTSLTVLILRNNSIESIERDAFTSLGTLVELDLSHNQISHLPEGIFDGLHTLEILRLRNN
PLFSLPVDVFRGMKKLVDLDLAEIIIGNINVDMFQGLTRLEKVAFDKFEYCRYAPHVRTCTPRSDGISSFENLLKNVVLR
VFVWTIGIITSVGNLGVLVSRAFMKAENKVHTVVVINLCTADFLMGIYLLIIGTHDVKYRDNYNQHALEWTNGITCKVSG
LLAMISSEVSVLTLMFISLERYFIIVYPYSFQRIKTRRAIMVLAFIWFFGTLLAVVPIIPVDYFGNFYGSNGVCFPLHLH
EPRMRGWEYSVVVFLGINSTAFVAIALSYTGMFLSIRKTRRAAAQCGMKGDMAYAKRFFFVILTDSLCWLPIAVLKVMSL
CNFIISETLYGWIIVFVLPINSALNPILYTLSTTSFAMWFMRQLKRGKFKTSGCYIGSNVDMSELRGRIEESGAFTSYTN
MPKRASFFLPTRKHHVSSKVEAIPAVSSSVPSRSATTTAMTNNIRPLHTINEGEIVDNNSQSQGNHQLRRTPIVRLCDLM
E

>NP_001091924.1 secreted protein, acidic, cysteine-rich precursor [Strongylocentrotus purpuratus | PB0006
MMKIFIVLCLASLAIANKHEMLADQELARAKIALDELTFTKEEHIYNVDGYVEGEKEIGYENEIDDPCANMECRIGRECV
LDNQREPFCDCATSCPQGETSEDAIHRTKVCTTTNATFTNLCEFHRQKCMEVDLMEVHVDYYGECAEMGSCSAEDLREYP
ERMTNWFIKSLALIRNRPEEHGGLSQKEKETLQQEWSQSTHAIFWKFDRLDKNPSDHYLDFAELEGLRAPIVLFEPCTKP
FLQACDVDNDTLISAVEFGRCLNLSDEQVPY

>XP_011665896.2 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 [Strongylocentrotus purpuratus | PB0007
MAQRPMLILTVILCTAYIVSAQCPGICDCSSYDSRKEIRCGTRGLTSIPSSLPPDTQILRLEFNRIENISATDFSRMVNL
KQLTLYNNMISFIDTNAFQYQQDLEVLNLKYNRIRFIHSQTFRNTQKLLELSLDNNLLQSFGNDTFSGLVKLNELEIVGN
PLQSLPEGIFNGLTNLLLLDISNVVFEAIPSNLFDGLTSLETLKMNNVTQNGGHLFGSEIIFASVPSLITLEVRQNSLHC
LPGSLAVLRALKVLILSMNPLTCSNFTVLKHLQHLEQLHMEDSGITRLSSNMFVGNTNLVFLLIEYSNLSTVEEGAFTGL
SRLEDLYLSSNNITTLPDHVFDSLPSGVNLDIADNPWYCDCYLRWLHTWLTTSYTGNTPDERQPECVSPNRLIGQRIIDI
VESEYACMPQTELNETMTHSVNEGENFVIECSITADPSPALHWLTPDHTELLPNTNKIPFIVDSESTLTIIRIRKVDAGT
YSCTGTNAAGTLNIRNVVNVVGTGNTPILKTDPHLQSSTTITSQQSEPLKGGENSTLVISIAVVAFLIILVVVVVIVAVI
RRRNKRRDRFRHGPEAAFRNGRATLPSLPSCTTQDNMAMPYAASDDRYTLQRPPTTSVFDPPPPYSTIPSSPNDDIYQEI
KTDDDLYEKPREPGDMSPTSVRPDHTYMIQVLRQDSFVSNGSGGVPAGYERSMIRDVGKPKSDTSSTRGSAGCSDQPANG
AQRNIYVATNDVKDNNRQSNTEHNDLRVRVPDLDPEAKATYENTRRT

>XP_030837109.1 sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1-like [Strongylocentrotus purpuratus | PB0008
MDECDTTFGSTCQFQCRDEYRPMAGQETITCLDTKQWSGNPLQCEKITCGILPDLNHADRIYSSPDRSIGSVCELRCEPG
YEFKRGAITNVTCQRGSEISAQWSIEDDEQDPCKKVSCPVLYVDNPKRIDPAGICLEIPKFEQVCTYDCKRGYQAEGTVD
SVTCLADGTWSIPAADITCRDIEPPTLTCPEDISNPTDIFMPISTINWEVPEATDNTPFPVKLRSTHSPPYRFDINTTVV
TYSATDLAGNVATCSFNVTVRDEEPPRLTNCTSEVTFQDIGLDPFGDLGIDEEEWNTSQFNDNSGTLSNDVLGVPSGSRF
PLGDTEVVSRATDPSGNTQDCNVTIRVSKYHCEYYPPPLNGAVACVDSPGGQLCRISCQKTFHFTKDRVEIYACIANESG
QHLWSRSDGDHEPLDMPWPDCAKRRRVRKASLKTGFRYDGTCFNETSQKNIRDDFISVFDFLQTRGDLGPCSLSDTQCSF
ENVNVQCSQTQRRKRRQVIDGSGGIDVVEITFTLLVEITETVGPDVNVLDYLDAAVNSVQESVANGNVTINVDGIELSLS
DDPIVPESEYSILCDVGHIPSNGSCVPCAPGNFENQGVCERCPVGTYQDEYGNTTCKDCPLDTSTAALGARSINKCKALC
HPGTYSTSGLESCNACPQGTYEPGRGSTSCTTCPDGLTTWTIGNSDVEHCTNLCPRGTFSPTGFAPCQECPKGSYQPAPK
QTSCTLCPGDLYTHHEGAHAIEYCQVINECVSNPCADGATCVDVTHGYDCVCPPGFAGDDCQLDIDECFGNDVCLNNATC
TNLVNAYVCECANGFKGENCQINIDDCLTADCRFGSICVDGIASYTCECAEGFAGEHCEINLYDCASDPCRNGASCIDLK
SNFSCCCAPGYTGRLCELDSNHCQSSPCHGDATCRTTRNSYICTCPSGFQGRNCEINVNECLESAYCLNGGTCQDMIDGY
RCICPLGFNGDHCQTELPKNYDLSFPTARTADRVGLEGVLPDLYEFTLAFWMKTSDKTNFGTPISYATRGSDGASDMDNT
LTLQDYNSFVFFVNGQSAFTYVRANGDTNWHYISVVWTSETGEWVFYLDGSQAASGTGLSTGTFVKGRGMFVVGQEQDTY
NGSYVVKESFIGSLSQVNIWDYSMTRDEIQSLQSCCSSSGNALSWAQLSTGLRGALRRSEGSEICNGGACRNQGDCRNIE
CQQGGVCGIHNGQPVCRCPNGFTGRHCQFVNNGGCDHHCQNTVGSFICSCRQGYALQLDQKTCNSVSFCKHNGKFHSAED
SWEEGCNSCACQDGRAECSPKLCPGLDCQGLETEVVLPGDCCPVCLPEMKTCSVSNEGHYETFDGYTYDQHGECRYVLTH
DYSGTSNFEVHMEHQFLNANQTHLGVVILVYIDCLEVKIDVNGQVFVQDETVGLPYAHRNPANVRIAHVDGGRDVEVFSN
KGLTVTWSQTGGVSVNLTVTHGADVKGLCGNMNGNKKDDKMTRQGIRTSKNKELVHSWKVDGYKHCKQRNTRPMKFGYLK
IGRCSSVSYKDFGLAFRKCRVFFKNNFKRCVSEVDPKPYITNCIEDTCTCGVRQPCHCEAISSYVNECRRHLGEDIEDWR
SLSNCALQCPPTMSYDECGPPCLPTCEDPDGQRCTGTTACVAGCLCFAGQVFHNGACISRSLC

>XP_011666177.1 leukocyte elastase inhibitor [Strongylocentrotus purpuratus | PB0009
MSEYIRNMAFYKQQDISEQLVQLSSANTRFALDLYQTFQDERRGTNLFFSPLSISTALAMTQLGACGDTATQIADVFRFN
QVDQDQLHGTFKELNNLLYQTNSGYKLHAANRLYGKSGYNFVQSFLEGTASYYGAAIEAVDNFAAPTATHSINDWVSKQT
EDKITNLIPPGILNDLTRLVLVNAIYFKGNWESKFRAENTTQETFKVLDERKKVPVSLMIQKGKFALAVDKTNDCLVLEM
PYQGRNLSLLIALPVKDDGLGNLQTKLSADILRSWDAGLKSRQVNVLLPKFKLEAEFQLKEVLKRMGMPDAFNDGKANFE
GISGDRELYISAVIHKAFVDINEEGSEAAAATAVAVKLGCARPREPEKPTLFRADHPFIFMIRHRPTKSVLFMGRMMDPS

>XP_030844960.1 soma ferritin [Strongylocentrotus purpuratus | PB0010
MASQVRQNYHEESEAGVNRQINLELYASYTYLSMAFYFDRDDVALKNIHKYFLKASDEERDHAQKLMTFQNQRGGSIVFQ
DIKAPHKTQWSSAHDAMKDALDLEKSVNQSLLDLHKVAANHDDAQMTDFLEANYLTEQVEAIKELGGYVTNLARVGAGLG
EYMFDKEHFE

>XP_030842675.1 glyceraldehyde-3-phosphate dehydrogenase [Strongylocentrotus purpuratus | PB0011
MVIQVGINGFGRIGRLTLRAALENSEVQVVAVNDPFIDLEYMVYMFKYDSTHGQFKGDVKCESGNLIVNGKKIKVFQQMN
PSEIPWGENGAEYVVESTGVFTTIDKASAHMRGGAKKVVISAPSADAPMFVMGVNEDKYEAASMNIVSNASCTTNCLAPL
AKVINDNFGIEEGLMTTIHAYTATQKTVDGPSAKKWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV
SVVDLTVRLKKPASYDTIKKTVKAASESKALGRYLGYTEDQVVSQDFRGDMHSSIFDAGAGIALNDNFVKLVTWYDNEYG
YSFRVIDLILFMASKSS

>XP_030844513.1 trypsin-2 [Strongylocentrotus purpuratus | PB0013
MLKAIVLLSCVAAALADCGKPAVDPVNTFIVGGDAAMPGSWPWQVGIRKNYLVGQGGYHMCGATLIDNQWIVSAAHCFYR
WKRLSDYTITLGSHDRDEVDSTQVNAKLGGIFVHEDYNSMTLDNDIAMLKLETPIDFNDAISEACVATSDYPADTMCVVT
GWGDQEAAIDNAELQQVYVPIIDTKVCNRPSWYNGEITDNMFCAGYSSGGMDSCQGDSGGPFVCKNSAGAWELTGVVSWG
YGCADPLNPGVYTRVTQYNDWISGIKRNN

>XP_030844513.1 trypsin-2 [Strongylocentrotus purpuratus | PB0014
MLKAIVLLSCVAAALADCGKPAVDPVNTFIVGGDAAMPGSWPWQVGIRKNYLVGQGGYHMCGATLIDNQWIVSAAHCFYR
WKRLSDYTITLGSHDRDEVDSTQVNAKLGGIFVHEDYNSMTLDNDIAMLKLETPIDFNDAISEACVATSDYPADTMCVVT
GWGDQEAAIDNAELQQVYVPIIDTKVCNRPSWYNGEITDNMFCAGYSSGGMDSCQGDSGGPFVCKNSAGAWELTGVVSWG
YGCADPLNPGVYTRVTQYNDWISGIKRNN

>NP_001073015.1 lysyl oxidase-like 2 precursor [Strongylocentrotus purpuratus | PB0015
MQFSVGLFVQYFIFILITCGHGLPSNNETNTNNPTINTESTPIEPTTIAATTTTTSKPTTAKQEETTTQPPKTTQPTTVQ
PTTTQPTTTPTTFPPTTGEPTTRPPAKIRARLADGMHPWEGRVEVSMHGGSWGTVCDDGFNMNAANVVCKMVGYKKAVQY
FFGSSQFGRGPGRILLDEVECLGTEKNLLACEHNPIGVTDCSHSEDVGIRCIDVVRKVTPPEKKLKQYKFRLVGDPTPKP
QSEGVVEVMMTGKWRTICSDGWDMEDARVLCGSLGFKEATSVEPNRKNKSRQRKKSIVASNFECTGNEHNVSDCERTILK
SHKDCLSKRAAEAKCERGPFVMDADKPYSPPWSDVRLKAGAAFGEGRLEVFHAGRWGTVCGEDFDKVAASVVCRKLGFGT
AETVLENASAFGQGIGPIWLWEVDCKGTEASIMECGHGAYNRSKCDHSQDVGIKCNIPDLGVKEDIRLVQGRFDTEGRVL
INYEGQWGHPCGGDSWDMFDAKVACRQLGLGYAHQPMRSTRFMGRSGYPILMLDVNCTGNERTLSECPHVRSDNGTCMAD
YKAGILCAGVLPDVLMDVHVLQSSIYMQDWPMYMLQCAAEENCLSSESHVRGARRLLRFASAIMNRGTEEFRPVLGRSSW
EWHACHRHYHSMDVFSTYDLLDADGVRVAEGHKASFCLEDVYCDSGAQKVYSCDAGTQGISVNCVDIYRNDIDCQWIDVT
GVPQGSYVLRVDVNPNHIVGETDFTNNEVLCDVMLTYRVRIQNCRYADDS

>XP_030830328.1 histone H3, embryonic-like [Strongylocentrotus purpuratus | PB0016
MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFK
TELRFQSSAVMALQEASEAYLVGLFEDTNLSIHTNMSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVK
RISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG
>NP_999675.1 alpha-2 collagen [Strongylocentrotus purpuratus | PB0018
MYSFVDQIRQHRQTLLLILATITVFAVVCQGQESSFSLSISSGEPLLPCVYRGQPYLHAESWSVDECTICSCDNPTTTCV
IESCQPAFCVEPIKPEGECCFLCPFNVKVKKVAPVITSTGSISEGRENRLTLRVPIKFQEAQDTTGVAGEGLWRLSAWAS
PNMDGRGQRFGYQSQTLTEAQQAKHYKKKDSFNFQDVDFRLTDPMAQCTDMMYICTRLDRGESPRTKGGLDYEFSGFPDD
NALTGCTTAPECKGVQARGLSWRYTADNIIAGMENELSIDATVLFTDTTAPVTGNNLWRLALYGSKNLDGSGERFNYNEQ
TLNSMEVSKNLEEGGPLEFTEATAMFDVAAIGCGPFGYACMDFTRNDDADPFFGFSVLPEGEVITLCQESPCRADLSITR
VQDTVLSGTVIDGRDSNAYSMDVAISGAGVGVAGNGLWKLNAFGSSNANGAGQRYSERSQVLTSGQQDQTFRVTEDMLFS
NVDFDLSMRGLTCAEVQFVCVEFAKGDSPDTVFNLIPVPDDSVMVSCSPAECEGVVARGLSWRYTASGIIAGMENELSIT
ASAVFTATSPAKSGLDLWRLGLFGSENEDGSGTRFNYNVQTLNDVEVSKSLAAGGPLEFTEATAMFDVAAIGCGPFTYAC
MEFAKNEDASPDFFFSVLPEGDVITLCQESPCRANLEITNVGNRVLSGGLLNERYSNPFSMEVAIRGQGVGVAGEGLWAM
SAFGSSNMNGVGQRYSERNQVLTGDQQDTTMLVTEDMLYASVDFDLNMSGLTCTEVQYVCVEFRKGGFPTTIFNLIPVPD
PSVLVSCSPAECEGVFAEDLEWTLEPVEPVFPGEESSVSLDSTVTFRDGNRELVGSGLWRQGLFGSRNRDGSGERFNYKR
QTLDRPQASTTLIADSPLEVQDAITDFEIGTVGCNDFNYLCLEFTGGDNPNPDYFFRVIDAMDNSAEANTLVKCKEQECL
SKAIFTDLEADLGNQIIYENKRNPLTVDLTGVTHDDATNVRGDQLWKMAVYGSRRADGSGPKAGLEEQILDPTEASTTLL
DEENLMMNNVNFEFDMTGIRCEDAEWVCFDLDKNNRASVNYIFEARPDESVITECIDMRDRCKGVTAIDIDWEADVGDAP
FGEPSPLTLTADINFDPLSPDVNGQGLWQLGVFAATRPDGDGPRRDEISQTLDPFNGAKPLEEGGPLEFDNVLTNFPIDE
LGCDDYRYLCVEFKQGVAPTPGYKFETEAGTDSIISCREQPCRGVEVSELHSQPTETLSDLILYEGKDTNPIQYNSVATT
TPDSGTVRGVDLWTLSQWGSERANGNGPQQNYQEEVLSGYHAALPVMAAGDTLDFVPLATNFDMTGLRCPQVKYICNELS
KDPRSRPDFEFTAVPDETVLRSCFEVPDGACKGVVFTDLDWDMSHGPVSADGPDDVRFNVDVSTLPESGGADGDGLWRIG
VFGAQNPQGTGPRLDYKRQILTRGQSSTPAEGEGMPLELNALETGFDLSQIGCDSEYRWLCLEFAKGLRASPDFEFEING
GGDVIISCKEQPCRRPVMINDVETNPLGNVRVNEGTRNNRILYEMTALTDPSSGKAQGKNLWEMSTFGSSFPDGRGRRFN
PQTAYTFTQYQKDKSAFPGENIRYGAVDTNMDMTGLTCNDVRYFCSELRKGDYPSPDFEMIANPTEDVLTDCFELNCEGV
LIDNTRLSLNSDSELSDGPNDLSFDFTVNSNPTGGDAAGNNLWRLETFTSNNNDGSGRRDILRTQTLDPADASYDLDAGN
TMVFRNLEALVDSADVNCEEDYYLCAELSKHVAASSGFSMRATRENALTSCRLIRCAKAAPPPVQGRPGPKGAKGEPFDI
PPGMVGPPGRPGLAGSVGYHGRRGPNGLSGPAGQRGEDGRDGNSGNRGTPGPPGPPGPPGEMTAAAQQSKGPAYTAPIYN
TAPGRPGSAGYSGHRGARGPQGLTGPMGPQGSAGPMGMSGPRGARGEDGEDGNDGQNGRQGEIGLVGISGRPGLGGMHGM
SGNPGHKGWGGRHGAPGAAGERGEAGEGGNMGATGPVGAVGNPGQRGPSGSRGGAGSKGPMGDSGERGSNGEQGPTGNMG
PLGPSGLPGANGATGDSGMQGGQGSSGPVGLVGESGSRGKSGSAGAPGIPGSSGDSGIIGEMGIQGEVGGPGRNGAPGLQ
GSIGPVGIGGERGDAGLPGYMGLTGSRGPAGPSGARGIGGEPGPAGNSGSEGETGSTGPSGPRGPMGELGMGGGPGMLGA
PGNSGFMGDQGESGEQGSPGEPGSRGTNGEPGTPGQTGPNGAPGEDGLAGNDGKTGATGTPGRSGPPGANGDRGGMGPPG
AQGPPGIGGETGFNGNTGIQGTPGTRGEAGVDGEPGAAGQSGLPGSPGNRGDSGTQGPVGIGGSQGAPGQPGLTGTRGAR
GNNGPSGPRGGLGVSGDAGEQGLRGAAGLQGASGIVGERGTEGRSGRNGEVGPTGIGGSMGQPGLRGLPGPPGLRGGVGG
LGEMGTQGDRGPSGPSGPSGRTGEAGGLGPLGPMGVTGQRGDNGNPGDPGPNGPSGLKGTRGAGGEKGSMGSRGIPGNPG
PGGAPGERGPSGLNGEKGEAGPFGSQGRPGRSGPQGNMGARGERGETGNQGALGPSGSAGMNGPPGVVGEPGPTGPVGPT
GRSGEDGRMGSRGPQGNQGVRGPPGVQGLMGSQGSSGEDGRDGHVGPPGPMGSVGQAGNLGNLGSHGFMGPPGPAGPQGR
PGVSGEAGRDGANGERGEGGRMGPSGPVGVRGMPGSDGRDGKDGPAGPVGLVGGRGDTGAKGNNGMNGLMGPRGPSGIMG
AQGERGNRGKQGAQGSVGNVGESGGTGPMGSMGPAGARGEVGSQGATGHKGQNGMPGMPGMMGVAGEPGNNGEGGPQGIR
GIPGVVGEGGKSGRGGPRGPPGLRGGNGGRGERGNLGPSGPPGPAGPPGPPGEVSMAAMPRMPQQQQSKGPSQYSHYYRD
EIPKTVEQLDRTQFQIYLAKFESEILSLIEPLGSRDQPIRSCKDLFKCYPEAEDGNYWIDSNEGSVKDAFLAHCVKRGES
GSPETCITPRVDEISRARWYEGASGSRYITEMGLEKFSYEASEVQLTFLRLLSTKAHQNVTYHCKNSVAVRDRQTGSTEQ
ALRLMTTSDVELSLDAPSQEQYEVIEDGCQERSAEWSQTVINYSTRRNTRLPIVDVAPSDIGGEGQEFGITLGPVCFS
>NP_999674.1 alpha-1 collagen precursor [Strongylocentrotus purpuratus | PB0019
MYSFVDLAVCHRRKILLTLLVLFAVQSFSNGQAAGQYSEGPRGDKGQKGEPGDADINSANFPPGLPGPVGPPGPSGPSGP
AGNNGPPGPNGPRGNPGMDGLTGLPGIPGPPGPPGKSGSLVASAQTSSFNKGPSLAGYQYPQAQAAGTPGPRGPPGPPGS
RGPQGLTGPSGPSGETGPSGNSGPPGPSGLPGRPGSDGDDGTPGSQGQRGPAGTPGSRGTPGMPGAPGMKGHQGLPGMTG
SKGERGEGGERGSDGSPGPVGAPGPAGPSGQPGERGRTGPAGSQGDRGADGATGSQGPPGSTGPAGAPGMPGISGAKGDA
GSPGARGSPGLQGARGERGSEGSQGQTGPPGVPGRDGSNGAKGSAGPSGAQGTPGFPGARGPPGPAGSPGPAGSKGDQGN
PGQPGAQGESGPLGPRGETGPAGPPGAQGESGERGSRGALGPAGPPGGVGERGPMGPPGMSGAPGAPGAKGDRGLPGERG
SAGSKGSAGESGRPGEPGMPGQRGLTGPPGKQGRDGKPGPAGAPGEPGNSGPAGASGQRGLPGLVGLPGPQGQRGERGED
GGQGSPGAPGLTGEPGKRGEPGVAGPPGPQGSAGERGNQGPQGQAGSMGPPGPPGASGDAGAQGDNGPPGESGPEGPPGA
RGERGAPGERGPQGLTGAQGRRGIGGRAGNYGATGPPGQKGEMGPPGNVGLQGPPGELGPSGPPGARGPPGPSGSPGPDG
PAGAEGDRGPVGPMGPSGPSGMPGERGDNGEPGPGGAPGQRGDPGDLGPQGSPGSPGFAGPPGRSGNPGPQGELGPTGAR
GETGGPGPSGPTGDPGPQGPLGAPGQQGERGETGPQGQGGPPGPIGSLGAPGAQGPPGPTGPSGNAGSPGQPGARGEPGQ
SGSPGQPGLAGRTGPSGERGDKGNDGQSGPPGPPGPAGPAGQSGILGLAGGSGPRGPGGPAGPPGAAGSRGPAGKSGDRG
SPGAVGPAGNPGPAGENGMPGSDGNDGAPGPQGSRGEKGDTGASGANGSPGAPGPIGAPGAAGASGPRGETGSTGAPGPL
GPTGARGSTGPAGPSGPSGPAGERGETGPAGHKGHPGVSGLPGLQGTSGPMGEPGAPGEQGQQGTRGLPGARGSNGNDGP
SGPRGFDGPEGPRGPRGEGGSSGPPGPPGPPGPPGPPGQVQSSYGVRYPSFQSGGKGQGSSPYGYAYRDDSKNDAVKIQD
TELLGAISALGQQIELIKAPQGKAKTNPARSCKDVFLNNVEAESGYYWVDPNLGCQKDAIQVYCEAETGATCVPSTNNVV
SNMTWYVGKTKRAFFSSMHGGDKFAYIEDSTQMTFLRLLSTSARQTVTYFCKNVQGNPIFLSSSDVELVDDQDSKFNYRT
LEDGCSSSSSQWGKSVYEYETKKTTRLPIVDFAPGEVGSESQMFGLEMGPVCFS
>XP_793568.3 ADP-dependent glucokinase [Strongylocentrotus purpuratus | PB0020
MFSNTFVIGVVLIAVSLYYSVHFNHDRSAISVESQIAIAWGNVIAAGFSLHGLRNKSRIAVGVNVNTDLIVSGTAVLKKL
GIDSSGQAIDNAVIESLEELEQTFAFSLKNGAAIERIFSRSEDFEKVVQAADSLDEKQYFVGGNAALAGLKMADTWKGLE
VLLIGPCGPRVRALLPPNIIVPKPSYKETDEVHLIMEFKRNERWGDYEAKVATRFISSYDVSNTEMSALSEFSRSVTDFS
PDAVFFSGLHLLDGQPGVKKEEKMAALNQELSRLPSDLPVHLELASMADPELIKGIYTQVLSSVHSLGLNEQELSFMSSV
NSGPHPEVYIRDGYPEVGAVADILYWILTSTQQGSWLTKAEQSSAAGWSSTLTRVHFHSLAFHIVATMNGTWINNAAAVS
AGARIAGRQACDDGRIVDEKVELRVPQAFALSINHAPLRHRIVSVDPQNPVISWTRDNIQFHFTPVLVCKNPVKTVGLGD
AISSTGFLFSQMVSSS
>XP_030841141.1 lysyl oxidase-like 2 isoform X1 [Strongylocentrotus purpuratus | PB0022
MQFSVGLFVQYFIFILITCGHGLPSNNETNTNNPTESTPIEPTTIAATTTTTSKPTTAKQEETTTQPPKTTQPTTVQPTT
TQPTTTPTTFPPTTGEPTTRPPAKIRARLADGMHPWEGRVEVSMHGGSWGTVCDDGFNMNAANVVCKMVGYKKAVQYFFG
SSQFGRGPGRILLDEVECLGTEKNLLACEHNPIGVTDCSHSEDVGIRCIDVVRKVTPPEKKLKQYKFRLVGDPTPKPQSE
GVVEVMMTGKWRTICSDGWDMEDARVLCGSLGFKEATSVEPNRKNKSRQRKKSIVASNFECTGNEHNVSDCERTLLKSHK
DCLSKRAAEAKCERGPFVMDADKPYSPPWSDVRLKAGAAFGEGRLEVFHAGRWGTVCGEDFDKVAASVVCRKLGFGTAET
VLENASAFGQGIGPIWLWEVDCKGTEASIMECGHGAYNRSKCDHSQDVGIKCNIPDLGVKEDIRLVQGRFDTEGRVLINY
EGQWGHPCGGDSWDMFDAKVACRQLGLGYAHQPMRSTRFMGRSGYPILMLDVNCTGNERTLSECPHVRGDNGTCMADYKA
GILCAGVLPDVLMDVHVLQSSIYMQDWPMYMLQCAAEENCLSSESHVRGARRLLRFASAIMNRGTEEFRPVLGRSSWEWH
ACHRHYHSMDVFSTYDLLDADGVRVAEGHKASFCLEDVYCDSGAQKVYSCDAGTQGISVNCVDIYRNDIDCQWIDVTGVP
QGSYVLRVDVNPNHIVGETDFTNNEVLCDVMLTYRVRIQNCRYADDS
>XP_030834960.1 bone morphogenetic protein 3-like [Strongylocentrotus purpuratus | PB0023
MDTLLPESGVRRRRSAGSNDTKETLDENETLVSNEVVDVEPVDNNEYPLNPIGKTFPATTHTAFSFFAEQNMRRIKSNRR
RARNQRKKDKSKNMMLDAEEKSRARKKKLNKPRPKHLDIGTPTEATNVCDRHSMNVDFQAIGWDDYVIAPATFQAFYCAG
QCAYPIQKELHPSNHALIQSIMHLLGVQTGVPTPCCVPDKMEPLVLLYIEQDSTVTLKKYSDMVVESCGCH
>XP_787649.4 fibulin-1 isoform X2 [Strongylocentrotus purpuratus | PB0024
MKVYISLITLLVCFSFCHASLIDVMPDCCERGASFAGLGRTCDDLEAIPDIAPGDHGICMVIMKSCCANSLGPVLCERAL
NHRMNVGSCQTMNNDTCFSAGRECCDCCELGINAFHDGIECESMRTGTSCDRAFAYCCKAAASSFDENECSLQTSHRLCT
ERCVNLIDNYVCECHPGNHLLEDNITCVADGDTRPPPRYLACSQAPCQHECRQVGREYECYCRTGYELLSDGYTCEDVDE
CAVTDSLACNYAERCLNTIGSFNCISDVVCRSGLKYDPVNQYCVDIDECAERTDTCDERSICENRYASYTCQHASCPTGY
YYDRTVSQCNDIDECARGTHECLDGARCDNLPGSFHCTRIVPCGTGYTINGVTQQCVDVDECSQQSHDCEINELCINIRG
SYDCQSCPRGFKTNGNVNRCTQDINECQEGTFDCREGTRCENNVGSYTCISICMTGFEYNRILRACMDVDECRRGLANCA
TYEICQNTNGSFSCGCRQGFRQNNYGQCVDIDECREGLSECKPNQRCYNLQGQYQCRNMCRNGFRFNNFNSACEDIDECA
EGLDVCQNNQRCINQEGGYVCQCPAGHQANRDRATCEDIDECSLGLCRGTCENLPGSYVCTCPAGYALMENNVTCKDLDE
CSTGTDTCIQDEVCFNTRGGHKCESVVCPEYYQVRTSNDNIQCVKTCPRTGNAPDCPPGNLNSTISHTFVALPSIPFLRQ
PIRLLTIGLPNYRSAYGGSSQTYFRSISGNEDQYFVITRLFPRGLPTGYVSLQKPISGPFETVLHLEIVTEVRNPVTRRT
EVTATSYLMIHIDVGEQSY
>XP_030848293.1 lactadherin isoform X2 [Strongylocentrotus purpuratus | PB0026
MVRSFLRQPSLYASLLVLRCLLFDNFERFYWRHQPSAMEQDTTILLLALLSICWTGGHCGPIQDGSPLGLESGAIPDSSL
TAFSEWDANHGPRRGRLNMAKVGGQAGGWSAKTTDLNQWIQVDLLATYRIVRVATQGRADYSQWVTSFKIACSMDNVTFD
TVKDPTNTDNDNIFPGNSDRNTVVYNRFPVPMSCRYVRLLPYTWHQHISLRMELFGELLGHFQDASPIGLESGAIPDSSL
TASSEYDANHGPFRGRLNIARDGALYGGWSAKTNDLNQWIQVDLLATYSIVGVATQGRQDYSQWVTSFKIACSIDSTTFD
TVKDPTNTDTDNIFPGNSDRYTVVYNRFPVPISCRYVRILPYTWHERIALRMELFEELLASTEVSTTLNTSCEGAVAMNA
SPRTCTKPIQLFTILFGVVLRWLY

>XP_030853890.1 collagen alpha-1(V) chain isoform X2 [Strongylocentrotus purpuratus | PB0027
MSILGDGGWHRVALRVSGNQVSLTINCLTPQKWTIERSIRPFPLDQGVFLLFGSNINGKANFDGLIQQALIIPDPAAANL
QCTDYDVDCAGAANVFLEEARLPDLNTGEQVNGPVNVYDGSGYGEGSDGFSYDISVIDPGLKVVVAGEGAGPISASGDNR
GSKGQKGNQGESRIEHYAGPVGPAGPRGYAGPPGPDGPSGGPGVKGERGRPGRDGVDGVNGLRGPPGPSFIVPAAVMSAM
SDAASSSKGPGSQANLAAIRQVLEEQRIAMRGERGPPGTQGSNGPLGPPGPDGPKGDPGSLGDFGPRGPSGTPGQPGRSG
KRGRPGKDGGRGPAGIGGEKGDRGYDGLPGLPGVKGTFGRSGDTGPQGDSGPKGRNGEEGPYGDPGPSGPPGIRGAPGSR
GPAGPQGISGLEGEPGGPGPKGPVGLPGVAGGPGPMGKHGPVGAMGPQGQSGPPGVQGPVGKPGIPGVPGTDGPAGHPGQ
DGQSGAKGSMGAPGSIGVSGYTGPMGVKGARGIFGNSGQKGNSGMDGLPGFKGELGMKGERGQLGVPGPRGSEGIGGPKG
EQGMPGEAGPIGTYGDQGPPGPPGIPGYPGNVGEKGELGHSGKRGRSGRKGSRGPSGMRGPIGPGGPMGGPGSRGPQGIQ
GVPGEYGEQGERGPPGPVGDQGPPGQQGPRGFAGGKGPNGPPGQDGMPGFPGSRGESGMDGESGTPGPAGVIGPQGPPGE
PGSSGPTGFPGPPGSPGEAGLPGNDGLTGPQGVSGPVGPPGIQGPEGARGFSGERGLRGEQGIEGMKGEDGPPGQSGPPG
VQGQLGPPGPPGGVGLPGRPGDQGPIGPSGERGDAGEEGSMGPAGRDGMPGPRGPPGPIGQPGPQGPEGERGDSGPIGIK
GTKGERGEGGPPGPPGERGPLGESGPPGDDGEQGIPGQSGPRGPKGEEGSGGNPGAPGPIGLQGMPGPSGSKGETGDPGL
TGAPGPQGNPGKRGSTGSQGIQGQPGPRGDNGAGGLKGDKGDPGPNGRTGRDGPRGFKGDSGVKGEPGSTGLPGNPGPRG
IEGPSGPKGNQGPLGFPGELGLPGPEGVPGTIGEPGQSGSDGDPGPIGMQGISGDPGRPGPRGRPGTPGSQGPSGREGPK
GDPGEDGPPGLRGDPGPSGDNGPQGPQGPPGLRGLPGPEGNPGEPGPPGAPGAQGQVGIQGPTGAQGDPGPLGPKGDRGF
LGRTGEVGIMGEKGDKGSQGEGGPQGPKGDPGSEGPRGVMGPEGPPGLPGRDGLSGAKGERGDFGVVGDRGAPGSPGQPG
PPATAEYLQAMLDRGMLTLRPDMYPNFGAGFGGGGAGASTDGEQTFEATGSDVPLSTSSSNPFGGTKRRKRQVGPSDLPS
DGDFLGIDELLGNGMQGIDDLPDMPFRYVPGFDELPLPYVKAMEVLFSSLDQLQTDVEGIKKPNGTKDNPARTCKDLLMC
HPKTQDGYYWIDPNEGCPDDAFYAFCNMTAGGDTCLAPDNTTGHTETKGYRKAVPGEWFLENLRGKEFSYQGGIVQLTFL
RLLSSKATQKFTYSCVNGVAWYDEAEDSFDNAIRLLASNDEEFTFDGLNQPKVIKDECKNKPSLGETILEVNTSKLHQLP
ISDFAPLDFGRRNQKFGYTVGSACFN
>XP_781087.2 secreted frizzled-related protein 5 isoform X2 [Strongylocentrotus purpuratus | PB0028
MIERVLVVLLAFAASSPGVWGQETETDMAMLGVNSRTYPLDLSGRPKETDCVDIPEDLSLCQNIGYTRMRMPNLLEHDSL
DEVRNQAKSWVPLLLQRCHEGTQLFLCTLFAPVCLEVDRPIYPCRSLCEEVQAGCGPLMESNCFPWPAMLQCDKFPEDND
LCIRLNMRNQNGTVEAQPFEMSAAMQEAYMMHFTQCHDDSLEDTLLRKFCNSDFVLKVKIKTIRESKDGKKYIGDPNPEK
LEVLKQGSLKTKDLQRLTFYVREGANCQCDMLERSGNYLLVMGHRDSKKNRKLFMTFVHSWEKTRDFRRAIKGFENPDMC
ENLETATEGRREEIAPQDAEPHEMTPADEVLLASQTNTPVNDGVYTTHQVMADETPSPKTNTRRERKRGKRTRDRPRKNR
ERENREMPVRRARSKWD
>XP_030852887.1 complement C3 [Strongylocentrotus purpuratus | PB0030
MGVSITMGSFVLIFVIAISASLVPGGVTQSSPATFFVTSPNVFRVDVPESVVVTLIRSTPNVQNVQVRVSLRRPGSGVHF
SEDTRAVSPGSSQLFTVEIQADNLMRNEGDFQHMVLKAESLDPSYPFQKETEILVTLQSGYVFVQTDKPIYTPNQDVIIK
VMSLDQEMLPSDRELHVEIIDPSGTSVKRLRQTQALPSGFLSGEYRFHSHPALGIWTVSAFYGPEFLVESSATFVVKEYV
LPTFSVSIETPKYILAGAYSVVSTINAQYVFGKPVLGRYTFKYGVIQDGTVQELGERQGLIGDTGRAVVTLDDLSTDFDG
PDWFDRFRGRHFHAKAIVHESATQFSEASINTKAIFVDSPYKFSRKRTVQYFKAGLNLQVNLDLTFANGDVATDVPVSVI
ATARFPGGREEPLRRTDIYGSQVDLRSNTDDQGGVSMDFGVQSSIRSIHIVASTHDPQYPNNQADMSFGVSLADSANGND
YLVIRPRYADYRSLNVDVTTDFLVQRIGTTGNEDIDLHFLCITGGKIVLQGVQQRISAFGTNLPITIRSNMVPRMRLIVY
YVTMDGSVIADSLLLGVEEQCRQNQEVSLEILPRHVGPERTVYEPNGEIRVEVTAPNNSYVGLLAVDKAVYLLRNKDRMG
KRKMYDWMRSYDTGCGPGGGQNTAQIFKDSGMTVLTNAGLDVAIREEIECVDEPTRKKRSIDRDQQCLYDPTYLVNCLAD
KPRLRRSGGGVGYQNGDVRVREDFKETWFFDVVSMPEDGSPYLYPISTSSSITDWHLTAVSFSPTQGMCISETTVSVFQD
FFIQLHLPYSVVRLEQTQVIATIFNYGIRGFEINVNFTVEDGLCTAENPTIRHVFVESRRAASAAFIVRPVEVGEFQITV
TAGGSVNKRDIVRKTLLVVPQGVMKRKGRSVILNPGRVMFSDDVTTPSPNNSFAQGTTLFGENQQFEQMTISLPEDSIPD
TESCSVKLIGIPTETTATDPIGGLDHLVRRPRGDGEQTMIFLAPTLFVYQYLIAVGSDTVEQEARIYDYIADGVVRELTY
RQPNGAYAAWTHRPGSTWLTAFVVKVFSQANRFTWVDPVHVEGSINWLIDNNQLPSGAFQESRQVFYQEMIGAVQGETSM
TAFVLISLLESRNLLVPANQKIDDAIGNATEYLVTHVEDIDRVYDKAIVTYALALAESPSMRIANDYLWGDRNEDDTGAV
SFTPDVANYRDGSQPYWLQRRPSAVEIETSGYALLAQIALHDYQKAGKVALWLSNQQNYGGGFVSTQDTVVALQALAKYT
ERPEFNTINMDCELATEQITVHRYHIGDDYVQEEVDVSQSIGRSLTIGCRGTGIAKAYVELRYNTEQSDIDTCPFHLNTS
AVEIDSNALRSQNVKGLRITVCTSYNGDGTTHMSILDVGLYSGFNAVEQTEPEIEGLEEMVNGSEIISSYEASSRSVIFY
LNQIPDDEDLCFTFSAKSYVVVGNVQAAAVHLYDYYDPDKSCTISYKPGPGSALLSTLCSESECICTGGSLDYCNIDPCP
GPYSIFELERAACASHSSYALKIRIDTEEIQEGFRIYRFTVLNPIKTGDEDVPHQAQRQLFINEDCDCPKVKGRNIGGTF
LLVGQKSLKYTTEQGEESFRYVYGPTSKLEVWLQTRRPRNAAVFDKLEQFENEMGIETACSNEI
>XP_030848589.1 very-long-chain 3-oxoacyl-CoA reductase-B [Strongylocentrotus purpuratus | PB0032
MSSYVPPTVVINIFAVIGVIAALNKILRVLWSILKNVKTFILARPLGLATDPKRHGKWAVVTGATDGIGKAYAEQLAAKG
LNIYLLSRSPDKLKDVATQIEQRYKVETKTFAVDFTGGGDIYPSIGDQLTGLDIGVLVNNVGMSYSFPQYFCELADAEKF
LPNIININCLSVVMMTNLVLPGMVERKRGIIINVSSASGMNPSPMLTVYSATKVFVDFFSRGLDVEYRSKGIQVQSVMPF
YVTTKLSKLRRETMTIPSPTSYVKTALATLGSGNRTNGCLMHNLQGWVVGSVPDWLLDSVQMSIHSAIRKVSLKKLAEKK
TK
>XP_030835585.1 annexin-B12 isoform X2 [Strongylocentrotus purpuratus | PB0033
MSYPYPTGGAPYPQQGGGYPPQAGGYPQPGGYPQAPAPAGYPPQGGYPPAAGGYPPAAGGGYPPPAGAGGYPPAPAPAPG
YPPAPGVGYPPQQPSYPPAPQPGYPPQQPGYGAPPQAGMPMPSDYGSMHGGGLPYGAQPNMGFAGAAMAATAFRPPPVQP
APVIGGPGMPQPQAAYAGAASIPAQAPPAQAPPQQRPAPVAAPVVAKSSTPTQQMANMSLSAGAIVRGTGTVKPKANFNG
QKEAEILRKAMKGMGCDETAVISIMTTCSAVQRRQIALDFKTMYGKDLEKNLKGELKGKLETIVLNLLYLPAEFDAHMLR
KAMKGLGTDEATLVEVLCTRTNDEVQAIKVAYKKEFSRDLEKDVISETSGHFKRLLVSMLQGSRSQDQRVDVEKAKADAK
ALVTAGEARWGTDESAFNAVLASRSYPQLRAIFNEYSKLVKYTMEQSIKREMSGDLEKGMLTIVQCVRNTPAYFAEKLYK
SMKGLGTDDDTLMRVIISRVEIDMVEIKQEFQRAYNQSLGRFIKGDTSGDYKKILLALIGGE
>XP_030839713.1 complement receptor type 2 [Strongylocentrotus purpuratus | PB0034
MELEPYIIFVISTVVGMAWGQTCTINECSEESLPKPMGSGLSGYTPGGTGCYDDGTLVTYICTGSLLGPPTSQCSAGIWF
PPVGPTCEAASGCFRPQLPPNGNVTEYKDEYALYDRITFYCDDGYSIIGPQEVVCDSGGIWDPSNIPTCEASCTAPSIQN
GGPNGTYVNGEVITYTCDVNYTLIGVSSATCRDELWDPTNVPECLEQCLPPIVANSNFDTQQDLFDHGSSVIIDCDPGYS
TGSSTSTTVNCNDGSLSMESPRCYENCSPLDTFLNGQVTGDTSPFYHTETVSFSCDTGFTLDGATSITCSDGAWDAPQPM
CMDQCPVIVPEAYSAFYGSAPPFQHGDMVTFTCYSGYEIYNGSITSTCQNGQWSSDPPFCTEQTTTTQAASTMMDSITTK
LPSTSMTTLQDTVTPSTSQSSDTSPEAASTDVVLQTDKDLNTSRVYRQVTFNQHDDYTRYNVAVYPNVNRSGIYRRPSNV
FRDHYRSCHRNEDLNTRRVYRQFTFNQHEDCTRYNVTVYFPNFPNVNRSGIYRRPSNVESHHD
>XP_030830576.1 uncharacterized protein LOC100887833 [Strongylocentrotus purpuratus | PB0035
MHFLDAWFPAGVLIIVCCLLSRSVAQLIDPEIRNITASAGDDVLLDCVPPDGEALLISWNKDNDVVQITDAYRDGRIFLD
QKEGMVILNSELWDRGMYSCLILTQDSQIITHRFWLDIAPPTDSDVDSNSAFQCGYCRVRGKVVGGKVSNEGQSPWTALL
WNTNEGKPLCGGVLLNRRWVVTASHCFSLSGLSIDEFEIRLGEHDIEAISDNERTFRAEQIIKHPNFNEQTYDSDIALIK
LQQPVTYTDYIIPLCLPSELRADELLKAETRGFVTGWGNTEEAGDYSRYLRRVRLTIASMQDCGRSHIDIITNNMFCADG
GRKADERDACQGDSGGPFVTKDNNRWYLLGIVSWGVGCARPGYPGVYTRVHRFRQWIMDLVQQDMQTCEESSFELGEELR
ASVKESNNLRLLNQEQQHLIEYFQEELNRKDEEIFDLHERIETFDCPDGLPTSTSPPESTTPTMTNYPVITETRPVTTRA
PIQEDALPCRHNMCWHVSNLARCHGGYCVCDSPDYSRVSCLPIVGSCRIYRNNSYALATATFRDDTRIADTFACEGNPES
NVHIISVYEGPVHTRPASPGDVHVRVTGGDQGPITIVFSSYEPVRWLVSVDEGIMINKFVLTGYYLDLSSVEVVSLLHTN
VTVVTVSRVPFGYGTDGDGVLHTAEFLKYVQNTYGDVGSFSGTYRADRWVLTVPGEAPIVDWMRLPLPIIPMARVESTLS
RTGWTPFPFRYDGSFCACHGDQYVKLLGGSENELDYGVRYVGVVLCQTPSHYKIFLANDLEETFLNVGDGSGGGSDHCEF
VGGHHENETLAQTSRDWLLMPAVSGYYRSVWGEPVSFGSIGGGYRTWTGKIIVSWYDCGITIP
>XP_001197113.4 serine protease HTRA2, mitochondrial [Strongylocentrotus purpuratus | PB0036
MAASMYRQSLKLSRLIRSNTPLLWRYSPTVNPQSTQVVISRTITQNQMHENQKIFFKRVAQFVGFGVFLYVISPWARQLK
GAKFESRRDKKRRRLAAEQNEVENTSISHGVPSLNYQESSPPSRGILPVVKAADVTDFGTGYVTPRSQQFNFIADAVAKA
SPSVVFIEIHGRHPYQRGVVGPISNGSGFIVSPDGLILTNAHVVANKRLGKQSVKVKLYDGRLVDGKVVAVDPVSDLALL
KIDTKDPLPVMRMGNSSAARPGEWVIAMGSPLSLSNTITAGIISTVSRTSKELGLNKSIDYIQTDAAINVGNSGGPLVNL
DGEAIGINTMRVTTGISFAIPIDCARDFVDKVQKQMKASGGGWFGKSGPQGPALTTPSKAGKQGYIGITMLSLTPSLIFD
LRQRAPDFPNVSHGVLIYRITMESPAQVAGLKAGDIITHINDQPIKSSQELYDRVQAKESLKVTAVRGKETMKLTITPEE
SQ
>XP_797859.4 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [Strongylocentrotus purpuratus | PB0037
MLSALSFFLAVAVVITIGDTSAATGNDNGDDQELLLLVVFDGFRYDYLEKTATPNFDRLVNMGAKPAGMTPAFATKTFPG
HHTIATGLYQENHGIIGNNMYDPEFNSTFGQANNEPRWWNYGGEPIWVTNQINGGRTVSVFWPGDRVNISGMTATYHQPA
YDGSFPNEDRIDLVVGLMSNGSANLGILYFSEPDNTGHLQGPESNETANSIADCDETLGYLLEKLTEADLLDDVNIIVTS
DHGMASVSPDQTVFLDDYVDRSLYFYTNNDPVFGLWPYDENSTEELYDALKDAHPNMDVYLKAEIPEEYHYRDNRRTSPI
LVVMEEGWHVWTNSSIEGNWQRYKGNHGFLNTLESMRSIFIASGPAFKSNYASNDLLDAVDVYNLMCHLLAVDPAPNNGT
FSHVEPLLANEGTGTSPETAETTLQMTTEGSGGRIAYSAHLLSLVFAIFLAFYF
>XP_792998.2 collagen alpha-1(X) chain [Strongylocentrotus purpuratus | PB0040
MELGCFSLQSLLLSLGLVILGLTHGEGLGPTKRPLPGHDERGTCRECCERGLPGQQGNPGYPGVQGPAGLPGNHGNNGNN
GPSGVQGPKGDAGPTGLTGSHGSKGDQGPIGLPGKRGQAGDPGIPGAPGKPNGAVNSQALGPRGPRGQPGTRGPKGEPGQ
GNRNSHALGRWSAFSFGSTNVVTASTHDDRILEFNHEFVNIGDDFDPERSVFTCHINGTYYFVMHANKWSNSRNLYIKLM
KNGDMVTAIYEDAGYDYYDGISNSLLLHLRRGDRVWLQLHSNNEVYGGLAKMTTFSGWLVRED

>XP_030846144.1 microfibril-associated glycoprotein 4 [Strongylocentrotus purpuratus | PB0043
MRTFSNLRVSSEHHHHLISYLTLFIIQLTSVFCYTVGNGRPNANPFASGSYNTYTGAGRASGTTANANPTSYGGATCSPN
VYVAPTINCSTNELQVELKRIQQDVAMLYENMQRLVDRVGSALPGVLPRDCKDVQQRGSTSSGTYTIQPDHNGWPFQVYC
DMETDGGGWTVFQRRSNGSEQFRRGWASYRRGFGSPQGEFWLGLDRLHRLTYQDEYELRVDMSDFDNIAVHAGYTWFRVD
DTASNYRLHVGEYHGIAGDALSYHDGQEFSTKDRDHDSNNTSHCARVSGEGGWWFNQCLETNPNGLYLGGHTERSREGVV
WTAWKGANYSLKTIQLKLRPVAD
>NP_999631.1 3 alpha procollagen precursor [Strongylocentrotus purpuratus | PB0044
MKYREVLERHVFVCLSLLIIVFAYWADAAACVGCLSATCICNGTKGERGDRGYVGFPGPPGPGGFPGVEGPPGYKGQKGN
LGIAGSGGPKGFRGSLGNPGIPGIPGIPGEPGQEGPPGEPGIPGCNGTKGERGPSGPTGFGQPGSPGPRGDPGPQGPPGD
TTYGLKGIKGEPGRLGRDGYPGTPGDSGPTGPKGISGDPGLLGSKGTRGLKGEPGQPGVQYQGGKGEKGSVGTQGLPGES
CRDQAATGNDTTIVQGRPGPKGDQGEYGDKGDKGFLGMKGMKGPKGQYGLKGEKGLSGPQGPRGKIGKDGTPGNQGMKGS
PGIPGNPGPTGFNGQLGDKGDRGPKGRVGPPGPPGPSVPVNDKGTKGLPGPSGRHGSAGPRGYPGEKGRTGYDGKAGQPG
PPGSAGDRGVPGPVGIGEKGEPGNPGIPGMPGPNGFQGLPGRDGPKGDKGMAGLTIQGLPGMDGRPGPDGPAGLPGQVGD
AGPQGLIGEPGNGLPGDPGPKGQTGRDGPRGIPGDVGSSGQPGLPGPQGSKGEACAACRSGEIGPKGDPGQSGEIGQPGQ
PVYNGNSGPSGPKGDRGLRGLTGRDGQDGPQGPPGSTGRPGNKGQLGLQGEVGFTEPGPRGIQGDPGLKGDNGLNGEPGP
PCEPGAVKVNGEKGALGPPGPPGRDGVPGYQGQKGDRGLPGDSLRGSNGEKGDQGPRGERGTYGSPGDKGEVVYYETGTQ
GPKGEPGNPGTAGPPGPAGPTGNQGLPGDQGPDGYQGEKGSQGQSGPPGNSIPGSPGEKGAQGIPGDVGQPGQPGPTGPL
GNPGIPGAFGEKGDFGPQGNPGGQGLRGLTGQPGQPGIGGERGNIGDPGTRGRDGIPGQAGGKGETGPGGLPGGPGIKGE
PGLSIPGQDGSSGTPGRDGAPGGPGEPGPSGPRGEPAQPLLEETRITRLNGQRRPPGQPGDNGAPGNDGEPGPAGQIGVK
GSPGPLGPGGSQGPPGSPGPIGAPGEKGERGGMGTPGSPGPSGSPGAKGEPGLPGPLGEKESRGPGGVPGSKGESGIPGR
SGGIGSPGSIGLPGLNGVKGEPGIPGNSGIPGGRGLNGEPGPAGFKGFQGLLGVKGDFGIKGQMGFPGPKGDNAQMGIPG
QNGGEGFPGRSGIPGPQGAPGSPGEPGTDGSNGGPGSKGEKGQPGIIRDLLAGWRKGVKGDPGRTGPEGAKGNPGLPGIP
GESGDAGLPGSEGRPGQPGTSGPPGPPGPNGEPGLIGRTGTPGDPGPRGERGSYGTPGEDGIPGVKGDSGDPGLMGLPGG
PGLPGPGGPPGESGFPGVRGVKGIPGTPGLSALGIKGEPGFPGLKGDSGQPGLNGGSGSIGLPGMKGTKGETGPVGPRSP
LPPVIPGPKGEIGIPGANGDRGDKGDRGEPGRPGFQGRPGESGSPGLNGQMGDPGGPGFQGLKGSKGEPGPIPNVFEMKG
VKGDRGGPGPDGPQGPPGRDGRPGPQGPPGLTGDKGTPGVQGNPGVSGVPGEPGLKGEQGFRGQNGQPGDPGFPGTKGEA
GIPGSSSGFFITRHSQTTSIPQCPQGTAKMWHGYSLLFVQGNERGHGQDLGKPGSCLKRFSTMPFLFCNINNVCHVASRN
DYSYWLSTTEPMPMNMAPIRGGQLQPFISRCVVCEAPAQVLTVHSQTVNIPDCPDRWGVLWIGYSFMMHTGPGGEGSGQM
LSSPGSCLEDFRSSPFIECHGDGKCNYYATTYTFWLSSITGNAQFTMPQSETLKAGSLRTRVSRCAVCLRNQ

>XP_030853449.1 sulfhydryl oxidase 2-like [Strongylocentrotus purpuratus | PB0045
MASSGAHLGFSTSKLLLIFTLSIGVKAVLYEPTGDVFVLDDSNFANNVFNSDKIWFVEFFSSWCGHCINFAPTWKSFAKD
LLDWRHVVNVAAIDCSNKKNTEVCRKHDVHGYPSLKCFFPFTKPENMTGVKLHRGGRDVRALREYVAAQIEEEAQKPHRL
KPWPDLQPAEAPWVSDFFTHHPNHQFLVIIFQGTDNFMGKEIILDVSNIEKVEARWMRKADNPLIEKWGVDSFPSAYILD
RSGAPTKIVGTDRGSFSAAIKQHIKDNANKQPPVEQILDDTNHYHGDEMLKKEHLLGPGGVVGKVIKSEGDNIESDFDGR
DVDEDGNLEIKEKEKEEEEKKNEMGLSLLLRPGDKGFVEMNKGGRGENDGGNAGEEEEGQGGGAEAGREKEAEGVGILRE
EVGGAGVGLDDVGVDEGLVGDEGEAGEEGGEGGGKQKMMWNKVLEKNKEKALQKKTNVRMSDQRPSEWPKVYMLDLESAI
QYSLRQEVSLRSHIEGEELQALTNYVGVLSKYFPGRPEVMSFLSTIHQWLLEKEGTSIPIQEWLTLVDPTKEPGIGLPDR
VEWIGCRGSEPQFRGYPCGLWTLFHTLTVSQASLIRRYDNVSYMEVLHAMRGYILAFFSCQNCRENFRHEVADLDDSITS
LDSAIMWLWQTHNHVNKRLHGDPSEDPTHPKQPFPSRTICASCYASTNVELWEERRVLRFLKDYYGLRNFAFKGIHASNS
GAADDTDMGTRATLNPEGVKQDVLNHLRQREMSIRLAVGTRRAGYFGLGINGVDLSMCMVLNVSCVMLIVCVYFVLVWRR
RRRKRLLPR

>XP_030832127.1 colmedin isoform X1 [Strongylocentrotus purpuratus | PB0046
MATDKQNECSCSFHIRILYFAFSILCFLTISMFVLTFCYVTQLRETRLCLPEASGEPYVRGTATISQSDRSQREFAGMGG
HPNANTLNENFHQIFEDGNDLEAEKGRKHGAEKGENGIYSEKTRNLSAIREEDGDISRRARRNVNGADGRRLQVLATVPI
SIPLSSIANVCNWTNGECPTGPKGNPGPVGLTGQIGQRGLPGPRGEPGVRGKRGDRGPKGQAGENGDRGARGEKGDMGLS
GPQGPPGIQGTQIDNCSCLGTRRSTADTHGVESIPLQELENKMRRILLQSSISGVVTIANDTSDTAELTISSFKSVKRSS
STPLATSSGESTGVQNDVTDDAYAAQDSEVDLGSDNHDARQPQALDQDRTLKQSENTRLRAGNDRIAEGTITDTAATKTD
VPTLLPAHALSTESRTMVLNAQETSEGSGPPFSDNEAEESAFLTGRNGANNINLVDDQEGMVTEPSKMTSDPNLQQMTTQ
GSTAEGEVTRMGIDEQKLMNISALLQRLNELTANKTSLLNFVQMSIAKTVTCGCPGPPGPVGPQGEVGPKGDRGLVGLTG
STGDKGERGSLIDGEGHILHGPPGPKGDQGISGSRGPKGDPGLDGVDGIMGLPGFKGEAGPRGILGEVGDPGPMGMKGSK
GDMGPMGTRGQMGYDGQKGRKGETGIMGHRGVPGSTGPFGPKGIKGDQGKRGEVGYPGLTGSSGPPGVPGTPGRDGMKGQ
KGERRIYVLPGGSVPPTEYSSLIPSDSNPTTKPANIEPEKMFKIYEPIVKSQCRLTNISSPREIHAMSRSYGAWMKDTSI
NSRHPDMIWVTMHHRGAILIEYKNLDEMKRRRLSATFALPFQWDGAGHVVYNGSFYYHHLNKDYIIRYDLTTGSIIERAH
VPSLGYASDDLFQLSSGYTNVDFAVDENGLWIIYPVTRPGSVGKLTVSKLDPESLEIITTITTDHNFESTANAFIVCGVL
YTTKGPHSRPSRVDFAFDLFREVVLEDISMNIQNRHRKTVMLSYNPRDRLLYGWDKGKLLTYDVAIKEYTDD
>XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus | PB0050
MDLLYYMTVSLLGFILSLTTFIGETTRALSDDVSSPCKASGFLGDIALTEDDYEREMIRARHNREQYRRRILQERHTRTT
GARHHIKKRTIEEAKVRHVRAVTARPERRWTDAVIPYEIDGNFTGSQRAMFKQAMRHWENYTCITFVERNPANSEHDNHI
VFTYQACGCCSFVGRKGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNIVPGQEYNFRVLDAAE
VDSLGETYDFASIMHYARNTFSRGIWLDTILPRKDPESGIRPEIGQRKHLSEGDIIQANLLYKCPSCGRTLLESTGNFSS
PEWPGQYDGDQTCVWRISVTPGETISLQFTGFELVGSDGCWYNYLEVRDGHWRHSPLLGRFCGASLPDPILSSDSRLWIE
LKSSAHRYSRGFAANYEAICGGHIERESGTLQSPNYPDDYHPSKECVWLITMPANYTVGLSFQSFEIERHETCIYDYVEV
RDGHEDTSPLIGRYCGYFIPDDIKSTGNKMMVTFVSDGSVNKGGFSADFFKEKDECAQPDQGGCMDVCVNTIGSYRCDCR
PGYELSSDGRRCEVACGGLFTGLRGNISSPSYPEPYPRDKNCVWQIVAPSNYRISLQFITFDLEGNEVCKYDYVDVRSGL
NEEGTLHGKFCGNEIPETITSRFNNLRIDFRSDNTVAKEGFFANFFADVDECEEGNGGCQHICTNTLGSYTCSCRNGFTV
HENLHGCKESGCRREIQSTTGIITSPNYPDNYPKRKECTWHISANPGHKIVLSFDDFDLEQHQECTYDRVQVFDGDSDEG
QVLGRYCGATIPDAVVSSSNHMFIRFYSDASVSRSGFSATHSTQCGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIV
SPDDHFIHLWFRSFDIEHETECNYDQVMILDGDNHAAESFGKFCGHRAPDDIVSSGDSLMITFSSDDTINKKGFLAIFKL
TDGELLEGAGEEEEEIYYN
>XP_030838573.1 collagen alpha-1(XXII) chain isoform X2 [Strongylocentrotus purpuratus | PB0051
MMELRKVLCSLRRGIVFISICTLFRINHIKAQLTETVECPGDIRLEENDLPGWDIIRMFELDSATIQGVRVVTGSDDVQR
AYRLLKNHDISEPASNQFPQGLPDEFSFVSTFKLTDRTGDDEDWWLWLIRDRAGTPQIGIRLMGEEKALQFIYVNELGQL
ENVRFDNAMMLFDRNWHKLHMAVSKNRLDLFVDCLSIGSVALRTRGQVDTLGETLIGRKFSAGGGPVQFILQWMIIHCDR
TFPTRDHCSEISISEATEEPKTCSTICPEGPAGRQGDPGLPGPAGQMGRPGIPGRIGSTGTKGEKGSEGYRGQPGPIGPV
GNPGPRGSPGPGGLNGDPGRAGLKGEMGSNGLPGLPGVPGDQGPRGYTGQQGDQGRPGDTPTREQLIDIVVSIPGLQGDP
GQRGLPGIDGVKGEKGTRGEYGYRGVEGPKGIRGETGLRGNLGEPGPPGPPGTLISTSNNTQVTQGPAGSPGIPGIPGDP
GIQGFQGDQGERGIKGLSGIKGEKGSGGLRGPRGDTGSAGEAGPMGPPGPRGDKGSAGPQGPQGLFGPEGERGPAGLAGP
RGGSGPQGESGPRGYKGATGSLGFPGFKGDKGSFGDLGLPGLSGPKGEKGGKGSNGLRGIAGVPGTNGNPGPIGDQGEQG
VQGNKGQPGLRGVRGEKGDEGLPGPMGLTGLRGTKGDIGNTGYTGLPGKDGDSGPRGPQGRQGIKGALGEDGGRGPVGLI
GIPGRRGSKGEIGANGKTGPGGRNGKDGQTGPMGPRGPKGERGDNGDPGSTGPQGPRGTQGYGGGRGEKGNKGDRGIGGT
NGQNGIPGLTPSKDEILRLIERYFQNNIESFEQRFRGPPGPPGESIQGEPGPAGILGLSGPTGPMGLSGNPGSMGRPGML
GGVGTPGERGPRGSRGQKGDRGQGYTGPTGAPGERGLPGKPGIGRPGKDGQPGFPGPAGLPGERGESGQVGDPGFCEYCN
YAPGTYPFQIPPAIDLNNKG
>XP_030828530.1 laminin subunit beta-1 [Strongylocentrotus purpuratus | PB0053
MIMAEDLTALYIVLFLSAVASYGQLILAGSGACEGDSCYAGDLLIGREDKLFASSTCGLNGREPFYIVSHLENRNREIFH
CDSRTPWQEGVNDLNHEIKHVVTSMDNSQKKVRWWQSENGLEQVYIQFDLEAVFHFTHLIMTFKSFRPKAMVIERSSDFG
HTWKPYRYFAYDCAGSFPEVSRAPIRNISQVICESRYSAVEPSTGGEVIFRVLPPNIPIEDPYSREVQDMIKVTNIRINI
TELHFLGDHLFDDGDEVFNKYYYALYEMVVRGSCHCFNHASRCVPADGMEFKQQMVNGQCECIHNTEGKNCERCEPFFND
QPWRPAGLRGENNECKRCNCNDHATSCHFDEAVYRLTNGASGGVCDNCLHNTVGRNCEQCKPFFFMHPDRDIRDPNICVP
CNCDPAGSENGGECASHTQGEMVAGMCLCKRYVTGQRCDTCQDGYWELNEANPEGCRECACDLLGSENNMGCDKSTGNCR
CKRYVTGQNCDRCYEGYYGLSADLYGCKQCECDPGGSYNNSCNQASGQCPCRRNIGERQCGQVNSGYFYVNMDYYTYEAE
YARAVGDLSLVDYYPRMRESEYIGWTGPGFMRVHEGGGIEFTVSNLPMSGNYDLILRYEPLLPGVWEDVRITINRPGDIP
TQSVCGNTIPQDDLLVTTLPSGSRHVVLSNPVCLETGKTYTIRVDFTRYSSDNQDSNAQILLDSLVVMPRATIYPIFQGP
DPIEQYRREQWDYYRCGEAHMSAVHSPLSDICKELMFSMSALAFDGALPCQCDPTGSLSNMCDETGGQCQCKPNVIGRTC
NQCAPGTYGFGPEGCTPCDCDGTGSLNEFCNQLTGQCPCRPNTYGQQCNECQPGFWNFPNCQRCNCNGHADICDPRTGEC
IDCQSNTAGFECESCKRGYYGDPTRGSALPCQACLCPGGAGSGNQFAESCQLDQATQTVQCDCFSGYTGIRCDQCDNNYF
GNPTEARGVCNLCSCNGNTLSSTPGNCDARSGKCLQCLYNTDGFNCEQCAPGFYGDAIQRTCRDCQCNVLGTDRSQCDLD
NNCGVCDPVSGQCPCLPNVLGQQCDRCAQDHWKLASGTGCEACNCCPYGAVSSRCDEFTGQCACRSGFGGRECCDCEANF
WGDPRDGCYECDCDEQGSATSQCERATGQCVCLPGVTGYRCDQCARGTTGELPRCEPCGECFDDWDLTILHLRNETYDLI
ARARNIKVSGVSGVYDREFSRLEGLVDYAESLIRGAPSVTETDVDNIQSELDDIRATLEEYRQQVQGLEDMQRRTRGNIA
RANRELDLLEREGDELQADAERLQRESYDFGTANVEGAMNSILRSQNLSRAAEGRVDDTQPTLDQSAAVRQEVEDLIGER
NAALESERQGYLDRLDDVDNQLTGLEGLLAGLNEEICGSPGDSCDICGGAGCGQCGGLGCGGSVQKAEDALRRATEADQK
LDQKEEEARSMLDEMMQAKDRTGEAQDLAQQAYDQALLAKQEAEQGQINIKDLINNITDFLGRSKSEPDDIRLLVNETLN
TKISLSPEEIEDLAEQIEDIIATLENIDEIIAATRDDLQRVNDLKARADAAREYAEGVLDSAEDVVRALNQAEAAQNIAD
NAINNATEDIEDAGDSLTSIESEARDAKDKSNNLLDKIEAMKAQLEGVQLKVTDNQEKVTQAVDLAEMAEGQALDVAGRV
EEMERDFNQTSDEVMAKVAEVEGAKGRADTLFLNVIAFEEKITKDYEDLQEMETTFNNNNATLHDLTAEIAALNMKMMQI
LMDIQTKAAYYRSCTESPTAP
>XP_030838572.1 collagen alpha-1(XXII) chain isoform X1 [Strongylocentrotus purpuratus | PB0054
MMELRKVLCSLRRGIVFISICTLFRINHIKAQLTETVECPGDIRLEENDLPGWDIIRMFELDSATIQGVRVVTGSDDVQR
AYRLLKNHDISEPASNQFPQGLPDEFSFVSTFKLTDRTGDDEDWWLWLIRDRAGTPQIGIRLMGEEKALQFIYVNELGQL
ENVRFDNAMMLFDRNWHKLHMAVSKNRLDLFVDCLSIGSVALRTRGQVDTLGETLIGRKFSAGGGPVQFILQWMIIHCDR
TFPTRDHCSEISISEATEEPKTCSTICPEGPAGRQGDPGLPGPAGQMGRPGIPGRIGSTGTKGEKGSEGYRGQPGPIGPV
GNPGPRGSPGPGGLNGDPGRAGLKGEMGSNGLPGLPGVPGDQGPRGYTGQQGDQGRPGDTPTREQLIDIVVSIPGLQGDP
GQRGLPGIDGVKGEKGTRGEYGYRGVEGPKGIRGETGLRGNLGEPGPPGPPGTLGDISIMEIVGGGETQLIPGPAGSPGI
PGIPGDPGIQGFQGDQGERGIKGLSGIKGEKGSGGLRGPRGDTGSAGEAGPMGPPGPRGDKGSAGPQGPQGLFGPEGERG
PAGLAGPRGGSGPQGESGPRGYKGATGSLGFPGFKGDKGSFGDLGLPGLSGPKGEKGGKGSNGLRGIAGVPGTNGNPGPI
GDQGEQGVQGNKGQPGLRGVRGEKGDEGLPGPMGLTGLRGTKGDIGNTGYTGLPGKDGDSGPRGPQGRQGIKGALGEDGG
RGPVGLIGIPGRRGSKGEIGANGKTGPGGRNGKDGQTGPMGPRGPKGERGDNGDPGSTGPQGPRGTQGYGGGRGEKGNKG
DRGIGGTNGQNGIPGLTPSKDEILRLIERYFQNNIESFEQRFRGPPGPPGESIQGEPGPAGILGLSGPTGPMGLSGNPGS
MGRPGMLGGVGTPGERGPRGSRGQKGDRGQGYTGPTGAPGERGLPGKPGIGRPGKDGQPGFPGPAGLPGERGESGQVGDP
GFCEYCNYAPGTYPFQIPPAIDLNNKG
>XP_797562.1 alpha-actinin isoform X1 [Strongylocentrotus purpuratus | PB0055
MAYYGNQDAYAYDDDDEDDYMKQEDEWNRDEVLDPAWERQQRKTFTAWCNSHLRKANANIEEISSDFCNGLKLMMLLEVI
SSEKLPPPERGKMRFHKIANVNKALDFITSKGVRLVSIGAEEIVDMNLKMILGMIWTIILRFAIQDISIEDHSAKEGLLL
WCQRKTAPYRNVNIQNFHNSWKDGLGFCALIHRHRPDLLDYSKLKKDDPATNLELAFSVAEKHLDIPRMLDAEDLMNTAR
PDDKSIMTYVSAYYHAFSGAQKAETAAGRINKVLGLNMENQRLMDEYEKLASDLLEWIRRKKPWLEDRTLQESTLDAMQK
KLDEFRTYRGKEKPPKTEDKARLETNFNTLQTKLQLTNRPAYRPSEGKLVSDIAKAWKGLETSEKGFEDWLLAEMRRLER
LDHLAKKFRHKCDIHEAWAAGKEEILREDFSGMRLNDLKAKCRKHEAFESDLAAHQDRVEQIAAIAQEMNDLEYHAIGPI
NQRCQTICDQWDTLGSLSMGRSEALAKAVMILESIDSRQLDFAKKAAPFNNWLDGAREDLMDMFIVHTLEEISELLDAHE
VFKNNLGAAEEEFNSLAALANEINKTIEMNNVGIKENPYTTLTVQVVVEKWRDLCELVPKRDEALSNELRRQQSNEQMRV
RFAQLANQVGPWIEKQMAATMNIAIGLNVPLESQLHKLQDYEHTVLQYKSNVDDLESCNKSVQEAMIFENPHTQYTMETI
RVGWEQLLTAIRRYINEIENNILTRDTKGITEEQLNEFRASFNHFDKNRTQRLEPLEFRSCLVSLGYDLREDKKSDIEFQ
RIMALVDPSGTGKVSFQSFLDFMTREMSDADTVEQVVDSFKVLANGKAYILPDELRMELPPEQAEYCIARMAPFNGTGAA
PGALDYMSFSSALYGQSEL
>XP_030829251.1 superoxide dismutase [Cu-Zn]-like isoform X2 [Strongylocentrotus purpuratus | PB0056
MQLLLALLSLTALITSSSAVTVNFASCRLTKSENGEVVGRVDLREQSDTNVLQLRLQVDGAKLTLAANSKHGFHVHTYGN
ISGSCSTTGGHYNPDGVDHASPTSAQRHVGDLGNVQADASGNIDVSFNDTYASLTGTKAIMGRAFVLHGGEDDIGLGGNA
GSLASGNAGPRLACCVIGWATGTDWVY
>NP_999708.1 high mobility group protein 1 homolog [Strongylocentrotus purpuratus | PB0057
MGKKDRDSSKPRGRMSAYAYFVQDSRAEHGKNHPNSPVRFAEFSKDCSARWKALEEKGKGVFHEKSMRDKVRYDREMQSY
KPPKGEKNKRRRRRKDPDAPKRNLSAFFIFSGENRAAIKSVHPNWSVGDIAKELAVRWRAMTAGEKIPFDKGAAKDKERY
IKAMAEYKAKAKPMKRQVKESSSSSSSDSSSDDSSSDDSD
>XP_030838586.1 melanotransferrin [Strongylocentrotus purpuratus | PB0058
MKTIVFCLLTIVSTALAATTQMRWCTSSTHEEQKCVAMRTAFSAQSLSPEVVCVAGSGISDCLMKVQDGQAHMITLDGGD
VYLAGKEYGLVPIVQETYAQDRYAGIAVVRATDSTLTLETLKGKDSCHTGVRRTAGWNIPVGFLLEAGYMEAVDCGDDIN
AVSNFFNQSCAPGAYLERNDPYGTNPPNLCGICTNKQCPADSSELYQSYAGAFRCLAESAGDVAFIKPQTVIDNTDGNGQ
LDWNRGLMSSDFRLLCPDNTQSTIDNAATCNLAKSPAHAIVTSPSTSAEDITAFQTVLAQAVALFGDDNNQNGFLMFDSV
AYGGNDLLFKDSTQNLANLESGLTYRTYLGDYANTIDGLKMCPANSLRWCTTSSIENKKCRDMSAAFKGANLTPQISCYE
ETSKGLCVDRIVSGDADVVTLDGGDLYAGGDRIAPIVGESYDVGGDNPDASYWAVAIARKGTQFGMDDLAGRKSCHTGIG
KTSGWNVPVGHLIKNEQIFVNGGCEVPKAVGEFFSAGSCAPGAKTDKYDPTGTNPSSLCALCIGTGNDNCVRNANEPYYD
YAGAFRCLADQAGDVAFVKHTTVPDNTDGNGAEDWSTNLNSADYELLCADNTRMPITAWETCNLAKVPSHAVVTSSTKTT
AQKQEIARLLLDGQEQFGSDSGAVFKMFDSQAYSDTDLLFKDSTEMLVDVGTQDTTEKWLSPEYVQDLDAISCSTTGGGA
TRTVQTSMVLVMMAFLIQMVWFGVLSRK
>XP_030835585.1 annexin-B12 isoform X2 [Strongylocentrotus purpuratus | PB0059
MSYPYPTGGAPYPQQGGGYPPQAGGYPQPGGYPQAPAPAGYPPQGGYPPAAGGYPPAAGGGYPPPAGAGGYPPAPAPAPG
YPPAPGVGYPPQQPSYPPAPQPGYPPQQPGYGAPPQAGMPMPSDYGSMHGGGLPYGAQPNMGFAGAAMAATAFRPPPVQP
APVIGGPGMPQPQAAYAGAASIPAQAPPAQAPPQQRPAPVAAPVVAKSSTPTQQMANMSLSAGAIVRGTGTVKPKANFNG
QKEAEILRKAMKGMGCDETAVISIMTTCSAVQRRQIALDFKTMYGKDLEKNLKGELKGKLETIVLNLLYLPAEFDAHMLR
KAMKGLGTDEATLVEVLCTRTNDEVQAIKVAYKKEFSRDLEKDVISETSGHFKRLLVSMLQGSRSQDQRVDVEKAKADAK
ALVTAGEARWGTDESAFNAVLASRSYPQLRAIFNEYSKLVKYTMEQSIKREMSGDLEKGMLTIVQCVRNTPAYFAEKLYK
SMKGLGTDDDTLMRVIISRVEIDMVEIKQEFQRAYNQSLGRFIKGDTSGDYKKILLALIGGE
>XP_780287.3 ribonuclease Oy [Strongylocentrotus purpuratus | PB0060
MNDFQITKMGIRVLVTAIIITLCLLNSRQISAWSVVELVSRLSSPKSPVAKQPSARDVQENAVFTNTRPAPGAAEVDKGK
FIFDRLSLNKQSSNDTWTELILTIQWPQSFCLDYNDGRDYKEAGECKVPAGIDDWTIHGLWPSNPGKLGPENCNSTWKFD
VTKISDLVAEMNASWPNCITDEAYDSLWSHEWDKHGTCASLLPALYGEHNYFQKTLTLRKQFDIKGMLEASAIVPSKTNS
YDYPTIFNAVKGAIGTDPTVTCVYDHKTQLVYLSQVEICLDKQFNPVNCVGLNSMRKSSLGEESCANDKLIFYPLVN
>XP_792998.2 collagen alpha-1(X) chain [Strongylocentrotus purpuratus | PB0062
MELGCFSLQSLLLSLGLVILGLTHGEGLGPTKRPLPGHDERGTCRECCERGLPGQQGNPGYPGVQGPAGLPGNHGNNGNN
GPSGVQGPKGDAGPTGLTGSHGSKGDQGPIGLPGKRGQAGDPGIPGAPGKPNGAVNSQALGPRGPRGQPGTRGPKGEPGQ
GNRNSHALGRWSAFSFGSTNVVTASTHDDRILEFNHEFVNIGDDFDPERSVFTCHINGTYYFVMHANKWSNSRNLYIKLM
KNGDMVTAIYEDAGYDYYDGISNSLLLHLRRGDRVWLQLHSNNEVYGGLAKMTTFSGWLVRED
>XP_030844552.1 uncharacterized protein LOC579853 isoform X10 [Strongylocentrotus purpuratus | PB0063
MNRAMMEGYTIILSLLLCLSVASVFSNDAILNGPGPLGLESYIIPDSSLTASSEFSADYAAKRGRLNLVREGNLKAPWIA
RTNDANQWIQVDLLDLYRITSVATQGRQDSSQWVKSYKLACSTDGTTFHTVQDISTNPAYDKIFTGNVDRNTIVTNILPV
PQICRYVRLMPVKWFGYISLRMEIYGEGPVIDINDCSPDPCENGGTCSNGVNTFTCACDPGYTGPTCGATISNGPGPLGL
ESYIIPDSSLTASSEYSADHGVKRGRLNLVRDGNLKGGWIARSRDANQWIQVDLLDLYRITSVATQGRQDYSQWVKSYKL
ACSTDGKTFHTVQDISTNPAYDKVFTGNVDRNTIVTNTLPVPQICRYVRLMPVKWFDRISLRMEIYGEGPFTDIIDCSHD
PCKNGGTCSDGVNTFTCACDPGYTGPTCGTTISNGPGPLGLERYIIPDSSMTASSEYSADHAANRGRLNLARDGNLKGGW
SARANDANQWIQVDLADIYRITSVATQGRQESSQWVTSYELACSTDGTTFHTVQDISTNPAYDKVFTGNVDRNTIVTNIL
PVPQICRYVRLMPVKWFGHISLRMEIYGEGPVIDINDCSPDPCENGGICNDGVNTFTCVCDPGYTGPTCGTAILNGPGPL
GLESYIIPDSSMTASSEFSADYGAKRGRLNLVRDGNLKAAWIARTNDANQWIQVDLADIYRITSVATQGRQEASQWVTSY
KLACSTDGTTFYTVQGISAYPGAVWIFTGNADRNTIVTNTLPVPQICRYVRLMPVKWFGYISLRMEIYGEGPFRDINDCS
PDPCENGGICNDGVNTFTCVCDPGYTGPTCGTAILNGPGPLGLESYIIPDSSMTASSEFSADYGAKRGRLNLVRDGNLKA
AWIARTNDANQWIQVDLADIYRITSVATQGRQEASQWVTSYKLACSTDGTTFYTVQGISAYPGAVWIFTGNADRNTIVTN
TLPVPQICRYVRLMPVKWFGYISLRMEIYGEGPFRDINACSPDPCENGGICNDGVNTFTCVCDPGYTGPTCGTDINDCSP
DPCENGGTCSDGVNTFTCACDPGYTGPTCGATILNGPGPLGLESYIIPDSSLTASSEYSADKGVKRGRLNLVRDGNLKGG
WIARTRDANQWIQVDLLDLYRITSVATQGRQDYSEWVKSYKLACSTDGKTFHTVQDISTNPAYDKVFTGNVDRNTILTNI
LPVPQICRYVRLMPIKWFGRISLRMEIYGEGPFTDIIDCSHDPCKNGGTCSDGVNTFTCACDPGYTGPTCGTTILNGPGP
LGLERYIIPDSSLTASSEYNADHGANRGRLNLARDGNLKGSWSARANDANQWIQVDLADIYRITSVATQGRPEASQWVTS
YKLACSTDGKTFHTVQDISTNPAYDKVFTGNVDRNTIVTNILPVPQICRYVRLMPVKWFGHISLRMEIYGEGPVIDINDC
SPDPCENGGICNDGVYTFTCVCDPGYTGPTCGTAILNGPGPLGLESYIIPDSSLTASSEYSADKGVKRGRLNLVRDGNLK
GGWIARTRDANQWIQVDLLDLYRITSVATQGRQDYSEWVKSYKLACSTDGKTFHTVQDISTNPAYDKVFTGNVDRNTIKT
NILPVPQICRYVRLMPIKWFGRISLRMEIYGEGPFTDIIDCSHDPCKNGGTCSDGVNTFTCACDPGYTGPTCGTTILNGP
GPLGLERYIIPDSSLTASSEYNADHGANRGRLNLARDGNLKGSWSARANDANQWIQVDLADIYRITSVATQGRPEASQWV
TSYKLACSTDGKTFHTVQDISTNPAYDKVFTGNVDRNTIVTNILPVPQICRYVRLMPVKWFGHISLRMEIYGEGPVIDIN
DCSPDPCENGGICNDGVYTFTCVCDPGYTGPTCGTAILNGPGPLGLESYIIPDSSLTASSEYSADHGVKRGRLNLVRDGN
LKGGWIARTRDANQWIQVDLLDLYRITSVATQGRQDYSQWVKSYKLACSTDGTTFHTVQDISTNPAYDKVFTGNVDRNTM
KTNILPVPQICRYVRLMPVKWFDRISLRMEIYGEGPFTDIIDCSHDPCKNGGTCSDGVNTFTCACDPGYTGPTCGTTILN
GPGPLGLERYIIPDSSLTASSEYNADHGANRGRLNLARDGNLKGSWSARANDANQWIQVDLADIYRITSVATQGRPEASQ
WVTSYKLACSTDGTTFHTVQDISTNPAYDKVFTGNVDRNTIVTNILPVPQICRYVRLMPVKWFRHISLRMEIYGEGPVID
INDCSPDPCKNGGTCNDGVYTFTCVCDPGYTGPTCGTAILNGPGPLGLESYIIPDSSLTASSEYSADHSVKRVRLNLVRD
GNLKGGWIARTRDANQWIQVDLLDLYRITSVATQGRQDYSQWVKSYKLACSTDGTTFHTVQDISTNPAYDKVFTGNVDRN
TIKTNILPVPQICRYVRLMPVKWFDRISLRMEIYGEGPFTDIIDCSHDPCKNGGTCSDGVNTFTCACDPGYTGPTCGTTI
LNGPGPLGLERYIIPDSSLTASSEYNADHGANRGRLNLARDGNLKGGWSARANDANQWIQVDLLDIYRITSVATQGRQES
SQWVTSYKLACSTDGTTFYTVQGISSHPRAVTIFTGNADRNTIVTNTLPVPQICLYVRLMPVTWFVHISLRMEIYGEGPF
RDINDCSPDPCENGGTCSGGDNIFTCACDPGYTGPTCGTAILNGPGPLGLESYFIPDSSLTASSEYGADNGAKRGRLNLA
RDGNLNGGWSAGANNANQWIQVDLLDLYRITSVATQGRQESSQWVTSYKLACSTDGMTFHTVQNIATNPAYDEVFIGNVD
RNTIVTNTLPVPQICRYVRLMPVGWFNFISLRMEIYGEGPITDCSPDPCENGGICSDGVNTFTCACDPGYTGPTCRTDIN
DCSPDPCENGGICSDGVNTFTCACYPGYTGPTCGTAILNKPGLGLESYVIPDSSLTASSAYTAEEEGFGTFSANKGRLNL
AETAWGAETADTEQWIQVDLLEPYRIIAVATQGNGKTSDPESFGYPGFYEWVKSYKLACRTDDTPFHTVLDINGDDSIFT
GNFDKNTIVTNTLSVPQVCRYVRLMPVTWHRYIALRMEIYGEDINDCSPDPCENGGLCSDGVNTVTCACLPGYTGPTCGT
DINDCSPDPCENGGICSDGVNTFTCACYPGYTGPTCGTAILNKPGLGLESYVIPDSSLTASSAYTAEEEGFGTFSANKGR
LNLAETAWGAETADTEQWIQVDLLEPYRIIAVATQGNGKTSDPESFGYPGFYEWVKSYKLACRTDDTPFHTVLDINGDDS
IFTGNFDKNTIVTNTLSVPQVCRYVRLMPVTWHRYIALRMEIYGEDINDCSPDPCENGGICSDGVNTFTCTCDPGYTGAT
CGTDINDCSPDPCENGGICSDGVNTFTCACNPGYTGPRCGTDIDDCSLDPCENGGICSDGVNTFTCTCDPGYTGLSCVTD
IDDCSLDPCENGGICSDGVNTFTCTCDPGYTGPTCGTDIDDCSLDPCENGGICSDGVNTFTCACNPGHTGPTCGTDINDC
SPDPCENGSICSDGENTFTCTCDPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFTCTCDPGYTGPTCGTDINDCSLDP
CENGGYCTDGVNTFTCACVPGYTGPTCGTDINDCSPDPCENGGICGDGVNTFTCTCDPGYTGPTCGTDINDCSPDPCENG
GICSDGVNTFTCTCDPGYTGPTCGTDINDCSLDPCENGGYCTAGVNTFTCACVPGYTGPTCGTDINDCSPDPCENGGICG
DGVNTFTCTCDPGYTGPTCGTDINDCSLDPCENGGYCTDGVNTFTCACVPGYTGPTCGTDINDCSPDPCENGGICSDGVN
TFTCTCDPGYTGPTCGTDINDCSLDPCENGGYCTDGVNTFTCACVPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFTC
TCDPGYTGPTCGTDINDCSLDPCENGGICIDGVNTFTCACDPGYTGPTCGTADPRPCETERRIRLEERGETENVFIPQCT
QDGFYAMEQCYKGNGTYCWCADPETGAVLPDSEVHGARADCDPINDCSPDPCENGGICSDGVNTFTCACNPGHTGPTCGT
DINDCSPDPCENGGTCSDGVNTFTCACNPGYTGPTCGTAINDCSPDPCENGGICSDGVNTFTCACNPGHTGPTCGTDIND
CSPDPCENGGTCSDGVNTFTCACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFTCACNPGYTGPTCGTDINDCSPD
PCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCEN
GGICSDGVNTFICACNPGYTGATCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGIC
SDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGV
NMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFI
CACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFICACN
PGYTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHT
GPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTC
GTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDI
NDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCS
PDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPC
ENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCENGG
ICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCENGGICSD
GVNTFICACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNT
FICACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNMFTCA
CNPGHTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACNPG
HTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGA
TCGTDINDCSPDPCENGGICSDGVNTFTCACNPGHTGPTCGTDINDCSPDPCENGGICSDGVNTFTCACNPGYTGPTCGT
DINDCSPDPCENGGICSDGVNMFTCACNPGHTGPTCGTDINDCSPDSCENGGICSDGVNTFTCACNPGYTGPTCGTDIND
CSPDSCENEGICSDGVNTFTCACNPGYTGPTCGTDINDCSPDPCENEGICSDGVNMFTCACNPGHTGPTCGTDINDCSPD
PCENGGICSDGVNTFTCACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTDINDCSPDPCEN
GGICSDGVNTFTCACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFTCACNPGYTGPTCGTDINDCSPDPCENGGIC
SDGVNMLTCACDPGYTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACDPGYTGPTCGTDINDCSPDPCENGGICSDGV
NTFTCACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNMFTCACDPGYTGPTCGTDINDCSPDPCENGGICNDGVNAFT
CACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFTCACNPGYTGPTCGTDINDCSPDPCENGGICSDGVNTFTCACD
PGFTGPTCGTDINDCSPDPCENGGICSDGVNTFICACNPGYTGPTCGTGSSSAAEVRLAGSGSSANQGRVEVYANGQWGT
VCDDLWGQRDADVVCRQLGFPGASSYTIHANTFGAGSGPIHLDDMRCVGNERSIMDCPKNAIGFHDCRHSDDAGVICRVG
QVSQSTEICRGTEVRLAGSGNSANQGRVEVYANGQWGTVCDDLWGLDDADVVCRQLGFPGASSYTIHAMIFGAGSGPILL
DDMRCVGNETSIMDCPKNAIGVHNCQHSDDAGVICHVNQEVRLAGSGSSANQGRVEVFANGQWGTVCDDLWEQREANVVC
RQLGFPGASGFTRGAMIFGEGSGPIFLDNMKCVGDETSIMDCPKNRIGAHNCQHSDDAGVICRVAQGSSCGAEMRLAGTG
SSANQGRVEVYLNGQWGTVCSDLWGLDDADVVCRQLGFPGASGFTMRARTFGEGSGPIFLDNVRCVGDETSINDCVKNAI
GFHNCLHSDDAGVICQLADRSMEDVE

>XP_030843507.1 contactin-associated protein 1-like [Strongylocentrotus purpuratus | PB0064
MVHSTAGAISWTALKTHLLVDDDTSDQDLCDAGWTRNGNACYQLVESTVDYRTALDACRNLNDYGDLASVADQDESNFLF
VYSRRTFDTSSYWIGFNDLDGKGTWAWTDGSVTSYTNWYSGEPSGGSEHCGVLRLSSDGTWYDASCSSTYGYICKYPLNT
ISCAEWKRKGYISNGYYTIDPDGRNNGVDPYKVYCDMTTDASTGITTFEHQEANRSLVAGAQVAFSFIRNITYGDKSVDQ
VATGADISGECYQYIKYECHHSQMTGSTAWYDRDGKQKNYWGGATVDSGQCACGISALDKAVFAIL
>XP_030855692.1 thrombospondin-1 [Strongylocentrotus purpuratus | PB0065
MEKIRCFSCFVLFIATLLPAIIAQSSYVEFNVLQDVGISAASPGVDLVRGQEENSVAYKIKPNKGDMAANTIDVQRLGDA
MNDEDGFVLVAKVKMGQKARGTVVSLDGHGHTDRLFGLVIDRKSDSVLMPYSYRRDGVTTQDSLEFSGLNLEDTEDRDWH
TFTLDIQGNLAILYADCTRVGLQIMYGSFVYDVTPDQYSLRLGKGLKGRKDVPDFKGIIEDVKFIFGQRGTRILRLQGCD
IEASSSQSSSSDISPDFGGQSHDSQLSPFGGGHESIPDVGVGVGVGVGVGVGVGVGPLVSQPNIHPSVHEVETPEQETIA
PVPPKMPEVPTVPNTPHTAIEPGVVEGPLNDGSPMNYNLPSLYLPNSPGSHNFAEPTNGARPMPNMNDVIPNGQCAITCD
QISQLRNMVDVLSQGQENILTRVTDMDNRIPSQTPPWLDGCFYKNEIRQNFEEWKDDACTTCECNAPAVTCRLIECQPIT
CQNPIIKPGECCPQCPNEEQGWSDWTEWTSCSVTCGSGTMQRGRSCDRMRYPCNGRSVETRNCIRDSCVSVVDGGWSNWT
PWACGITCGVGTETRVRSCNSPPPQNGGARCLGEAFGAGREERLCQRDPCPVDGAWGEWSLWTACTHSCDGGNQERYRFC
DSPTPAHGGRNCSGIKRQEQMCNQRPCPIDGCLSSPCFEGVDCRSSDDGVFQCGPCPVGFRGDGQSCTDVNECLEVLNTC
FHHHSQHRCINKIPGYSCQECPTGYRGNQPNGIGIFHASRYRQQCIPINPCTEGTHDCAPDAKCTFFGPYSQPQYGCRCR
TGYAGDGYACGLDSDLDGRPDVDLDCQGLGDYMHCHKDNCPRLPNSGQEDSDRDGEGDACDDDDDDDGIRDDRDNCQFTP
NRWQGDRDRDKVGDECDNCPTHSNPRQENVDGDEFGDECDDDIDNDGHDNFIDNCPKHANANQDDSDHDGLGDLCDNCPF
DFNPLQIDTDDDNVGDECDTDEDVDGDGHQDNLDNCPDIPNASQKDHDNDGIGDACDPDDDNDGVTDADDNCRLVFNPSQ
NDTDENGRGDACESDFDGDGVADIMDACPENSMIQRTDLSAFQMVPMDPSGASQLEPNWMVRNHGLELVQTINSDPGLAV
GYDEFESVEFSGTFYVNTAKDDDYAGFIFGYQSNHRFYAVMWKQVTQKYWQPDPSPAEATAGLQLKLINSTTGPGEYLRN
AMWHTGDTENQVKLIWSDPNKIGWKDFTAYRWTVQHRPIDGFMQVTAWEGSNVLADSGPLYDSTLRGGRLGLYCFSQEMV
FFSDMEYRCLSDY
>XP_030838586.1 melanotransferrin [Strongylocentrotus purpuratus | PB0066
MKTIVFCLLTIVSTALAATTQMRWCTSSTHEEQKCVAMRTAFSAQSLSPEVVCVAGSGISDCLMKVQDGQAHMITLDGGD
VYLAGKEYGLVPIVQETYAQDRYAGIAVVRATDSTLTLETLKGKDSCHTGVRRTAGWNIPVGFLLEAGYMEAVDCGDDIN
AVSNFFNQSCAPGAYLERNDPYGTNPPNLCGICTNKQCPADSSELYQSYAGAFRCLAESAGDVAFIKPQTVIDNTDGNGQ
LDWNRGLMSSDFRLLCPDNTQSTIDNAATCNLAKSPAHAIVTSPSTSAEDITAFQTVLAQAVALFGDDNNQNGFLMFDSV
AYGGNDLLFKDSTQNLANLESGLTYRTYLGDYANTIDGLKMCPANSLRWCTTSSIENKKCRDMSAAFKGANLTPQISCYE
ETSKGLCVDRIVSGDADVVTLDGGDLYAGGDRIAPIVGESYDVGGDNPDASYWAVAIARKGTQFGMDDLAGRKSCHTGIG
KTSGWNVPVGHLIKNEQIFVNGGCEVPKAVGEFFSAGSCAPGAKTDKYDPTGTNPSSLCALCIGTGNDNCVRNANEPYYD
YAGAFRCLADQAGDVAFVKHTTVPDNTDGNGAEDWSTNLNSADYELLCADNTRMPITAWETCNLAKVPSHAVVTSSTKTT
AQKQEIARLLLDGQEQFGSDSGAVFKMFDSQAYSDTDLLFKDSTEMLVDVGTQDTTEKWLSPEYVQDLDAISCSTTGGGA
TRTVQTSMVLVMMAFLIQMVWFGVLSRK
>XP_030828169.1 uncharacterized protein LOC752081 [Strongylocentrotus purpuratus | PB0067
MNTMEFILIRCGRIAGGRNATNNMSRTKRLQSKVAKQTITPLLMIIMYFISSCHATDPGQLRLMGMHNGEGIVEITNQDQ
WGLICASRWTMFDGDVACRQLGYEGVTRVMRVTPGREDRINAQVVLNGTNCEGMESRLVDCEHSGFGNFTESCQPMTLPW
VSCIGADIPEVTDEVGGGDLDTSNHVPVLSGRILPPVATVPVETFPAISVRHVGHDSVSLSWLDWYDRLRASDPRAYRVR
IIIKYRRVEVPGVQSTENYTIAAEVPTYWTDHTIRGLQPQTAYEFIVESVRLSMFGGEVIEPPSAPVYVRTVCGGPPPIR
HLHVEAPSNNATVLHIHWTMPADNGCSSDEYVIEYRQENLDQCEETSLLPGQTNRLTLAGVTTMTHLVVAALQPYSSYTV
FVSARNQFGRSRKVNSTKRTSETVPSDIPVNINHNFQSQNSLKLTWDPPSCGWRGGHIVTYAYMLIDINTDSVIHRGSTR
REFVVLTGVDSLQRYKFLVAASTQRGVGPFAVSDIPVEPNILHICGMAQERTARISTGMRAPRGAAPWMAQLWNVQSGRM
FCAGSIINEYWIITAAHCVEAQSHSASTLKIQLGDYDRLMPETHQRAYDVAEIVVHEGSQVQLDHDIALIKLSERIEFNN
YVRPICFPTTKLAKSFLKSGSYGSVAGWGRKGDNMDYPRYLNQVFVPVVERKTCRRATDYDFTSNMFCAGFREANRGDAC
EGDSGAPFSMQHANGRWYILGTVSWGDACDDQDKYGYYTRLHRYTSWIKRHTRVTTE
>XP_030855602.1 transforming growth factor-beta-induced protein ig-h3 isoform X3 [Strongylocentrotus purpuratus | PB0069
MRGIHQVSVIFWYERAKRGYKYGAWISSPHLVSSGSRLVERLSVSLPDYQATNSSTMHSVVVFLAVLVGAAVASPMILSP
DDVKQQNRDISATEYLKRIFEHSPKLLYSPIDVSSQGDVIDMLPALGLNEAALIAEQVNLRQILLELSSVTLCLPTDEAV
RRWREELPNTLKPDLASLKQLVKAWIIPGMIRSTDISNNQKVQSLNGAKLRFNVYNEIVTVNGARIIDADKMASNGIIQV
VDKVIFPLPVGNVIETVVDNQAFSIIVDLLKQAGLEEELQVSDPVTVLVPTNSAFRALPSGVLDDLKREKSKLQNLLKYH
VISDIRYSASLSSGQRIMASQGDEISVSIENGKIILNKAQDRSEASRVIQADIPTTNGVIHVIDQVLIPSQKHYVLV
>XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus | PB0070
MKLLLGIFAVLIAVVNCLPRDQFFPFGEGTTDKKLNRRSKKPLTLSFREPFTFLGEEQSLLYIVRDGYVSFSSGARGSKI
APFHTKLKLIRGQSSVWYRTTVSSNEEDEIINLIQRNFRSRGSTDFTTFSPSSFVIVTWENMAVRNSDHEVIGTVTFQLI
LVADAMHSFAFFLYDENNDYPRPDRIGSNIDAGFTSGKAHNQWEFEMVYTTEDNKAATLFEAMRDSNVGMNGMWAYKIDG
RMDGNIIPAVAYVPVESLPQNDEPPQDAVNIQLDNTFDVVLDFENQCTRETCSVDGRCVPYPTGHCCACNEGFMGNGIHC
LSINDNGRMNGRVNGTINGVTIPDEVYLHTFIMGGGGRTFTAISPVPSSIAYSMQILLPIGELMGWMFAEPAAKGINGFM
QTGGDLLYSANIRFENGDEVSIIQRYTGVDESEEGGGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVYTKYRPGYVYSSEQ
RSLDADGQTIRFSIEQTITYQECEADDINTDASLTAMRMNTTYAYSIFEPQGDILRYAMITNVGPDIGVPTDACQDNNCG
TNAECFPQANTFTCRCRAGYTGNGYTCTESPSDPCDNNDCDRNANCYPAGNSYTCQCNTGFNGDGRVCVADQASDPCDTN
DCSLYAYCYPTNDGQSFYCQCATGFTGDGRNCEREQRGNACDNNNCSPYAYCRPRGDTDFTCECAPGYVGDGYNCEEESQ
DPCLNNRCHPYADCSPVPGGYTCSCRSGYQGDGYLCEEADQLVNLCSDCGRDADCLPEGRGYRCICRAGFNGDGLTCEDV
DECLEGADIACDANARCQNNRGSYTCRCNAGYRGDGFTCEALPEADGSLVFGQGMSVMNLPRDGSAGNKVYMKSRQTVVG
LGYDCRHEYVYWTDISGRAIMKASLDGRDVSVVVNTSLSSPEGVAVDHLSRNLYWTDSGFDRIEVANLDGTNRHVLFDTD
LVNPRAIVIDPVGGYLYWVDWDRSYPRIEVSGMDGSGRAVFLDEDLIMPNGLTIDLVSQLLCWADAGTQKVECMNLDGDP
LSRYPVYRPAQYPFGLASLGNNLYWTDWQTSNIQFINKNGGEVQSLALPRGGNGRTYGIAAVTQCTDGNNRCAYENGGCR
NLCLPAPGVRATCVCPNALAPNDIPCN

>XP_030835262.1 carboxypeptidase D [Strongylocentrotus purpuratus | PB0072
MTLLLALLAVLPFFSSVLGEPITATSEFPGSDYQWEHHDQEALYQILRDTNEECPEITRIYSAGESVEEEDLWVIEISDN
PGKHEVGEPEFKYIGNMHGNEVVGREMLLLLIPYLCKNYETDPDIKWLVDNTRIHIMPTMNPDGYAAALEQLEERGENAW
STGRANAHEVDLNRNFPDLDRIIFGRRADRFPRRHGLNNHITSHVDPRQLEPETRAIMSWLQEYPFILSANLHGGDIVAN
YPYDSSHDGKANYEASPDDQVFRQVSLAYATPHPVMSDPNREQCDIGGEDAFKKGITNGADWYPLKGGMQDYNYLHTNCF
EITIELSCKKFPSNPNDYEEFWGDNKQSLLDYIRQAHSGIKGTVTDENGVGIDDAKIKVWELTGPASEEHYIDHDITTAD
DGDFWRLLVPGTYKVEAEACGFHAVNKTCTVAEPGTNVEASDCSFQLEEDNSTEGCSIEELESFLMNRLYPTY


>XP_003725040.3 sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 [Strongylocentrotus purpuratus | PB0074
MLDRTKLFHSKFYPFTGIRCATLGAPSSGNVGCTNTNFVSSVCTFSCVSGYRLVGSETRTCYRWSNTGLWTGSNPFCERV
TCNSLDDPTNGAWSCMGTSYYGSSCTLSCDYGYTLEGSQPTRTCLQSGQWSGTEGTLDCIDSLAPTITGCPSSQSVLAPP
LVTSAIVMWATPSAADNSGEAVTVVLEQGSASGSTFEEGDHLITYSATDNAQNKATCLFTVTVEVVYCPALAAHPPLQIS
CPQSNIRGSECTFSCSTGYSLQGQETQLCVLTGSTGMWNSITPSCQITQCNELPSLENGGITGACSRDYGSSCHFECHVG
YEINNDVRTCVAQPGSSSVFWDGESPVCSRIYCTKPSLSIGLQITVTSQCPSGRQVSSGNQCHFICSEGYHLQGSEDLTC
QEDHTWSSTIPTCQLINCAVADLSVPMFAVKQGCTTGEVNYGTVCTLSCQEGYEPTGSGEMTCSDDGNGVGTWSGDSIEC
TLVTCSVPIPVSTVTTVNCLYNGESTVTSERQKYSTACNFQCDDGYSLVEGSHVRVCLATGEWDGIPVLCRDITPPDLTC
PEDIVLKADPGMTMSKIQWSRWEPILASDLGMSIEATLYSINSDEVGPNRPSLFSEGSHTLVYEAEDVSGNKIDCSFSVT
AKVCRCPPLSIPENSIVSLAAGVGSCNGGVVYGSVCTIRCELGHTLSTGGRSLNRTCDISESGPNCDAMWSSPDPVCEIV
RCDVPDVTNGLSDCPSSTVAYLTSCGFSCEPGYRAPSGADSYLRTCQADSQWSGEDFQCTDLITCPARLAIPYGSATPSE
CSSSDFVQFGFTCEFTCQTGFRLEGPGSVLCNTDGNWSPNGDSFCVDIQAPTFDVACPHRINADALRERTTAEVYFQEPN
PIDNSGNATIKRLDLGYAPGSEFPEGDTRIRYKATDAFGLTSLCDLIITVNVHRCSVQQPPLHGAVTGCVDSFIGSQCLF
SCDVGYNLMGTSSLQCELTSDGTPAWNDLTPTCLIQTCPSLQIPEFASLSGCDSSPVPFGSICTFSCELGYTGIGESIKS
CLEEEVWSSTSFVCERLPCEVLSEPSSIMILPETCLSDPRFGDVCSLECEQSGFKITPPGLKEVTCSSDQTWTGEVEQAQ
CVDLELPVFEDCPSDIVAFASKSSDKANVEWSAVATDNDPSQEPVVTCNPQPGILTIGVHVVRCSALDEAGNEASCQFTV
EVKARQCQPLTPPAHGIVMDTCDTTYGSTCHIECSEGYLLVGSSIGNCEFDGTNMFWQFENEPLCITTSCNPLDVPDPIL
FSPASCSGSGMVHDGTVCTLSCDFHLTLETEVELFTCLKGEWSQQPYVSSIQCIDEVPPTLTYCPPHILTTRTEYWGVEE
SFVYPSAEDNFDMELQVTADPLDLMSPYTFTSDTTCTYTFTDDAGNSVSCVFQIDITNDVQPVITSCPTGGEVNTSDTVG
LVHYEKPSYLPMPGIDLLVSCNVPDSPIMLPVGDHDIICHVSDPASGLQAECRMSFKVMHESCLPLNSPMNGALACDIFA
DGRYCSVLCEDGYDVPRVLTGAGIAISLDVFICGTSGSWHPQQSVPDCSEPKSSKPNLPLKIMYYPSSCSEADASSIDTI
SSQFLEILEQSDFDSICDVNSQCSVDNVEVSCGVKNERRRRSIPDQRRPKLGRGSGGPTSVSMVLRLTDTMKLGQSKQPE
GQHPHQVLHNLAHHIHSHVQHHFSKADGDKKEDGIPGDAEHQRLKPDTTLLFGDVLAECDEGYYLDEDGFKCIPCPAGYY
LDVASEICTPCNQGFFQDDQAQTECKPCRDGTSTIDQGATRAEQCKEPCPAGHLSKSGFHPCTRCPPGLYQPHPQRTSCT
RCPGNTTTAMYGATSINSCHIVN
>XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus | PB0075
MKLLLGIFAVLIAVVNCLPRDQFFPFGEGTTDKKLNRRSKKPLTLSFREPFTFLGEEQSLLYIVRDGYVSFSSGARGSKI
APFHTKLKLIRGQSSVWYRTTVSSNEEDEIINLIQRNFRSRGSTDFTTFSPSSFVIVTWENMAVRNSDHEVIGTVTFQLI
LVADAMHSFAFFLYDENNDYPRPDRIGSNIDAGFTSGKAHNQWEFEMVYTTEDNKAATLFEAMRDSNVGMNGMWAYKIDG
RMDGNIIPAVAYVPVESLPQNDEPPQDAVNIQLDNTFDVVLDFENQCTRETCSVDGRCVPYPTGHCCACNEGFMGNGIHC
LSINDNGRMNGRVNGTINGVTIPDEVYLHTFIMGGGGRTFTAISPVPSSIAYSMQILLPIGELMGWMFAEPAAKGINGFM
QTGGDLLYSANIRFENGDEVSIIQRYTGVDESEEGGGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVYTKYRPGYVYSSEQ
RSLDADGQTIRFSIEQTITYQECEADDINTDASLTAMRMNTTYAYSIFEPQGDILRYAMITNVGPDIGVPTDACQDNNCG
TNAECFPQANTFTCRCRAGYTGNGYTCTESPSDPCDNNDCDRNANCYPAGNSYTCQCNTGFNGDGRVCVADQASDPCDTN
DCSLYAYCYPTNDGQSFYCQCATGFTGDGRNCEREQRGNACDNNNCSPYAYCRPRGDTDFTCECAPGYVGDGYNCEEESQ
DPCLNNRCHPYADCSPVPGGYTCSCRSGYQGDGYLCEEADQLVNLCSDCGRDADCLPEGRGYRCICRAGFNGDGLTCEDV
DECLEGADIACDANARCQNNRGSYTCRCNAGYRGDGFTCEALPEADGSLVFGQGMSVMNLPRDGSAGNKVYMKSRQTVVG
LGYDCRHEYVYWTDISGRAIMKASLDGRDVSVVVNTSLSSPEGVAVDHLSRNLYWTDSGFDRIEVANLDGTNRHVLFDTD
LVNPRAIVIDPVGGYLYWVDWDRSYPRIEVSGMDGSGRAVFLDEDLIMPNGLTIDLVSQLLCWADAGTQKVECMNLDGDP
LSRYPVYRPAQYPFGLASLGNNLYWTDWQTSNIQFINKNGGEVQSLALPRGGNGRTYGIAAVTQCTDGNNRCAYENGGCR
NLCLPAPGVRATCVCPNALAPNDIPCN
>XP_030838573.1 collagen alpha-1(XXII) chain isoform X2 [Strongylocentrotus purpuratus | PB0076
MMELRKVLCSLRRGIVFISICTLFRINHIKAQLTETVECPGDIRLEENDLPGWDIIRMFELDSATIQGVRVVTGSDDVQR
AYRLLKNHDISEPASNQFPQGLPDEFSFVSTFKLTDRTGDDEDWWLWLIRDRAGTPQIGIRLMGEEKALQFIYVNELGQL
ENVRFDNAMMLFDRNWHKLHMAVSKNRLDLFVDCLSIGSVALRTRGQVDTLGETLIGRKFSAGGGPVQFILQWMIIHCDR
TFPTRDHCSEISISEATEEPKTCSTICPEGPAGRQGDPGLPGPAGQMGRPGIPGRIGSTGTKGEKGSEGYRGQPGPIGPV
GNPGPRGSPGPGGLNGDPGRAGLKGEMGSNGLPGLPGVPGDQGPRGYTGQQGDQGRPGDTPTREQLIDIVVSIPGLQGDP
GQRGLPGIDGVKGEKGTRGEYGYRGVEGPKGIRGETGLRGNLGEPGPPGPPGTLISTSNNTQVTQGPAGSPGIPGIPGDP
GIQGFQGDQGERGIKGLSGIKGEKGSGGLRGPRGDTGSAGEAGPMGPPGPRGDKGSAGPQGPQGLFGPEGERGPAGLAGP
RGGSGPQGESGPRGYKGATGSLGFPGFKGDKGSFGDLGLPGLSGPKGEKGGKGSNGLRGIAGVPGTNGNPGPIGDQGEQG
VQGNKGQPGLRGVRGEKGDEGLPGPMGLTGLRGTKGDIGNTGYTGLPGKDGDSGPRGPQGRQGIKGALGEDGGRGPVGLI
GIPGRRGSKGEIGANGKTGPGGRNGKDGQTGPMGPRGPKGERGDNGDPGSTGPQGPRGTQGYGGGRGEKGNKGDRGIGGT
NGQNGIPGLTPSKDEILRLIERYFQNNIESFEQRFRGPPGPPGESIQGEPGPAGILGLSGPTGPMGLSGNPGSMGRPGML
GGVGTPGERGPRGSRGQKGDRGQGYTGPTGAPGERGLPGKPGIGRPGKDGQPGFPGPAGLPGERGESGQVGDPGFCEYCN
YAPGTYPFQIPPAIDLNNKG
>XP_795269.4 uncharacterized protein LOC590579 [Strongylocentrotus purpuratus | PB0077
MDFKTLLVLACVAAGSLAGPVRETQCAEECNSRDDEGMFRAFKSYYFSYDVEIDSRISGPTSDQSSTVRIGAVAVIEGLS
ACDMVLKLSDISILEKRQDGIMVAAETASTFSLALEAHPLRFSMEGNGTITSVCPEAGEEIWALNVKRGFLSHMQTKRTT
SNNVLEEGGAFETGVTGTCMPVYSPTGEMTFLKSNDFLMCKHRTNLNMFVDAIPVHLLAPTASPLTSRMECEYQMDSQSI
SSVECHETHALRPFAASESQPEIMVHTSITKTEVRSTISSSLSSEFARRTSLLYEDPIQVSEINSDDVRNTITQICNSIA
NGISSETPGLFETLTKQFGELDTNNMNTVINRLFRICPEVETNEVIKMVKDALTDCDTEQCAQGFHSIIASENSVENEFY
LRKWFMKLVFHKNPTKNMINLVKRYVGGNQEMNLPAYYALSSMIHQYCRMSEDDCSRDADILSAAIVFEDNLHDSCLPES
EEDEKKILMSVRAIGNMGLIQSKSLLNKCNRDQNPGLLRVAAIQAYRRASCNDVPTDRYMRIFSTIDNDSELRIAAYRAI
IRCPSETLLQGIANTMAVEPTNQVTCYVSSHLANLRNSQDPMVVDLQTAISQSPLANVTKCGMDYRKFSHNYGLSYFDDE
SGNGIHFDSDVVFSSQSYLPRSARLAMNVDLFGYGFDLFELDARTVGFQDALEELMTLSEEDREANMIEKVHRMMNKRVN
RQRREGIKTSALNRIKNQYETSHDVEEEAEGAFVAMKVLGNDVFYKDRDDIERMAERFSRERLMEIIASLVSQRSHEYSL
NKNFKTSKVTIPTIAGMPLEVNIQGAFNTILKASGKLDVLGMMATPRRMAVQGLFEPSAAIEINSNMMVDAHCARSGLSH
KTNMASSLSLGGSLSFENGMLKAKVTAPPRRETIIDASSSLFFMQRNEMVPVTEPEDAVTSIEETFANDRYNLHISGTRP
NMPFSLPQAFFQNWRMEITLDKLEDSLVSYDLEAGFRTDKAFRNGQIEKTDHLHLLLGAPGSETVGVYSMDLAYHRSNAT
LLINAETPQHGSIYVIGSLRNETNSKRLHLQATRSETTYMLEAGMDTIPLSNGIKFVPVFAVTIPDLVSYALEGHVSCTG
EEKLWDLSLVDNTERKLASLKGDFIKNNTLRRLSLSGSLGAFSSSLQGGYKFEEMSSSAIITPIFSLTSVFPAISLSIGG
GPLVIADSGTTMNEFYLTTANTRLIEVSNFHLQVRQRSFGFQGKIKETIPFGVEFDMTNDEQRQYSVDLTLTSIMGDYNI
QGLLFNRSADSIYRLEVIATVNSTEYFNLTTEFKNEVNAHQYLDTLVKFRGIQIFRSKNGLQIQALNAKTRFTPIFILET
NLLFSLSAEGSIDVSESGILINNMALISAAEDIFRLSGSASVDRDARSISWSFNVDGAYITEVVSGSASHHENTVLFQTS
MASDASSNQPDYSLTIDLQNSTKEGEIFSWDGKIELDMPHHPELSFRMDTEYTLTPSRSTGNVFRICYDGIDCTSTDKRI
TLGHDLTFNRVKNVSYSHDMEVTYTHPAADKDFTLDWTTNCTANVSSGTTLTLRDHEDDLFTTTITYIPEGSARNGSVSL
LVKAPGYFDYEYTDTFHFSNPKDILYLSKYRSGEQVMSFLVRFNMTGETNSSFWTSTVLEYTDIRNNDYTLEYIFAQTGS
ANELTSMTIKKNSELKMHMLEETTKESSDTRILFRYTRVLKTTFQPAQDLSYNLTVIVNPQTGNGNVDMQLRFLPGQKPI
LLIADYTNKSTDAKKEGHIIATLSLPKTSITVVCEGKLEKGVPSGNLSIKFQPLMRSAETYAIELAMKNRSSSPSQIYDT
ALIFRSPADVSYGIKHTVEYSEDVFFPLTSSLTGIWGEEEVTVSTSLTFDESLNMRTELDLSLAIPEHMYLFSGRFDRGS
RNITITKDSNIIWSSNYIQNVQESDAGSTFTLEIRESVMTYGSEMTLTLSNLSNAYAFNLQMQDNNREAIYTNWALDLFP
GQNRFDLTTESRSDFLPGYNTKTSLNFMKTEQSTTLSSSLNVDSTDMLSMTFTNAASEEPMSRTTQIVFRQPTNPDLRLR
QVVISDSCSMTAQGITHNTTLMWGNLLPTQAIALRFIGNRNEAGAGATIMLLNEGRVFGFGRLFTLALGKTRTATDQTGT
ITLTSETGNIFSLQTVLTNTSQGYMKDYDTSITMTVLDRHPITIGASLVHNSSNRVLDADLTLTYSADMNQKLTAGIELT
RVLNGHSIVLNLRHLVNIIDVTIIGTYSNSSNLFEMSLENSVLLGDERHQPELSFSLNRGTKEISFLYTGSRNYGFNGQF
LNRTTEEGRVYVINCRNNYNGRVVPYSMVFNEPRRIVGMVVQYNPENIADTWEFRAGYENDTAIFVSLDTVHSGQTIHNG
SLVISLDRNVSKVLTTQINWEPAWPQDLKAAVLNIVNKTMALRDVKRASMCSSWKALAQRINGTATGFLVSNVNIYTQIQ
LLKTQVNTQWALNSPTRMIQLGNLVGKWMRLNQTVHAYLASSDVKSGAYKAFAAKFEDIQEYFSTGFNMFSEDVVIDWMT
FEEALMAIQHEFNETAIASHWAASMEARDAFFNNLWTQFEEDILVMDPNWVALQERLNTICQNFGAVGQRIREEFNTRIA
VLKTEKRAIKRIIGAIAEDIEVFNAFLTPVIGQWKAAYEVEVEPFRNTDFSPFVTLVTELNETLRTLLNKDEALALYQMT
ATTFLDPYVFIARKRRQAPVPSRSADNLDAEAIKAALAKFNSRYGITNVRNEVTNPSAPVAVVPMEAGQDYNFTVLINVL
KKLFNGTYELTKFDMMNGEIVFKIFVKDFSNFTSLTNFTRQYLDMLPSGILERINVTKLEKMISMLREGTLSEFKSRFME
QFTANRTYYEDMMQELQTRMQGGIQDTMETRIVPYLERMGDRIVEGGRPFFGRVMDIPDREERHSFLEELTNELDMSSLE
RLYGRMKQTMCGVKNTMSAAVSKAMFATCPRTWMPPYGANALVIGAQHYMTFDKLFYDFSGKCGYLLAKDFVHENDFSAI
VDYERDMEIPIRNMMFMIDSRTFEIKSDGTVRVDRQARELPLQVGGTAIIRIGDSIFLKNAQGVDVMCKLPHDVCVLKLS
GRYFDRTAGLLGNFNFESYDDLKTPGNEVQTNITAFTESWKVGKNCIQSEAATLDLNRVIPTMDAIVNFDPLHPDNQACA
SMFLDNCSPLAGCHGGVDPDSFYRMCILDTRNLPQEERHSKMCSIAVAYKTQCWFSKQPVRMPDECIICEVGDESFQAGK
PITIEGEAVPRQADIVFVVEQKQCAEQDAQKLDNLVVRLAGDLQDAGFEDTQFGLAAFGGSGVYDAAHQHTINHKIFNDR
ARDFTLGRDSLEFTDGGSNDTFAAVKLAANYPFRTGAAKHIVLLSCSEYTEENPKLSFKELSVMLRKRAISLTILMDYQF
RLNKKSSASKSKSKTELVYGIDSTATYTSKMSGLEAFKGSATLRQFTDEPRGVNALLAQESGGAIFDSSMLSDKGFNDVF
VKRLVMKSEPAECQVCSCVHDDLVGVGRSVCEKCSNPLNVFGEEIRAGVRSFELKYRLPHHRYPDQIAEEEE

>XP_030853890.1 collagen alpha-1(V) chain isoform X2 [Strongylocentrotus purpuratus | PB0079
MSILGDGGWHRVALRVSGNQVSLTINCLTPQKWTIERSIRPFPLDQGVFLLFGSNINGKANFDGLIQQALIIPDPAAANL
QCTDYDVDCAGAANVFLEEARLPDLNTGEQVNGPVNVYDGSGYGEGSDGFSYDISVIDPGLKVVVAGEGAGPISASGDNR
GSKGQKGNQGESRIEHYAGPVGPAGPRGYAGPPGPDGPSGGPGVKGERGRPGRDGVDGVNGLRGPPGPSFIVPAAVMSAM
SDAASSSKGPGSQANLAAIRQVLEEQRIAMRGERGPPGTQGSNGPLGPPGPDGPKGDPGSLGDFGPRGPSGTPGQPGRSG
KRGRPGKDGGRGPAGIGGEKGDRGYDGLPGLPGVKGTFGRSGDTGPQGDSGPKGRNGEEGPYGDPGPSGPPGIRGAPGSR
GPAGPQGISGLEGEPGGPGPKGPVGLPGVAGGPGPMGKHGPVGAMGPQGQSGPPGVQGPVGKPGIPGVPGTDGPAGHPGQ
DGQSGAKGSMGAPGSIGVSGYTGPMGVKGARGIFGNSGQKGNSGMDGLPGFKGELGMKGERGQLGVPGPRGSEGIGGPKG
EQGMPGEAGPIGTYGDQGPPGPPGIPGYPGNVGEKGELGHSGKRGRSGRKGSRGPSGMRGPIGPGGPMGGPGSRGPQGIQ
GVPGEYGEQGERGPPGPVGDQGPPGQQGPRGFAGGKGPNGPPGQDGMPGFPGSRGESGMDGESGTPGPAGVIGPQGPPGE
PGSSGPTGFPGPPGSPGEAGLPGNDGLTGPQGVSGPVGPPGIQGPEGARGFSGERGLRGEQGIEGMKGEDGPPGQSGPPG
VQGQLGPPGPPGGVGLPGRPGDQGPIGPSGERGDAGEEGSMGPAGRDGMPGPRGPPGPIGQPGPQGPEGERGDSGPIGIK
GTKGERGEGGPPGPPGERGPLGESGPPGDDGEQGIPGQSGPRGPKGEEGSGGNPGAPGPIGLQGMPGPSGSKGETGDPGL
TGAPGPQGNPGKRGSTGSQGIQGQPGPRGDNGAGGLKGDKGDPGPNGRTGRDGPRGFKGDSGVKGEPGSTGLPGNPGPRG
IEGPSGPKGNQGPLGFPGELGLPGPEGVPGTIGEPGQSGSDGDPGPIGMQGISGDPGRPGPRGRPGTPGSQGPSGREGPK
GDPGEDGPPGLRGDPGPSGDNGPQGPQGPPGLRGLPGPEGNPGEPGPPGAPGAQGQVGIQGPTGAQGDPGPLGPKGDRGF
LGRTGEVGIMGEKGDKGSQGEGGPQGPKGDPGSEGPRGVMGPEGPPGLPGRDGLSGAKGERGDFGVVGDRGAPGSPGQPG
PPATAEYLQAMLDRGMLTLRPDMYPNFGAGFGGGGAGASTDGEQTFEATGSDVPLSTSSSNPFGGTKRRKRQVGPSDLPS
DGDFLGIDELLGNGMQGIDDLPDMPFRYVPGFDELPLPYVKAMEVLFSSLDQLQTDVEGIKKPNGTKDNPARTCKDLLMC
HPKTQDGYYWIDPNEGCPDDAFYAFCNMTAGGDTCLAPDNTTGHTETKGYRKAVPGEWFLENLRGKEFSYQGGIVQLTFL
RLLSSKATQKFTYSCVNGVAWYDEAEDSFDNAIRLLASNDEEFTFDGLNQPKVIKDECKNKPSLGETILEVNTSKLHQLP
ISDFAPLDFGRRNQKFGYTVGSACFN
>XP_011661993.2 complement C3 isoform X2 [Strongylocentrotus purpuratus | PB0080
MEGLKGLIVAIFASMAVLVYSGSAQLQTREKIFITAPNVFRVGVNETVTVSVFNTDQDQDVEVTIYLEKRERTRGLAWPY
SYTTVAVRRGTPVTTSVRVEPEHYSSPAEGGNQYVYLVASAPSLGFQEEKEVLLSSRSGYLLLHTDKPIYTPNQEVKIRM
VVVDQDMKPSSELIHLMILNPQGIIVEQFRETRAVNGFMNKTFTFNTEPMFGNWSVTVLHGLQFEKNKTIKFEVKEYVLP
RFTIKINTPDFILESSSRESLDINFEAKHVYKKPVGGNFHMEIGILQPDGIVVSKSTTVGTLENGIGTSSIYPRYNFGLD
WFRSYEGCRLNVEVVVTEASTGVTERAVDISTMIVRSPYRFRTGQTVQYFKPALPYEVQFELETVLGKPAQYLDVNIEAS
ALVQSRRLTLNHNMDPNANQQSTDANGRVRFIFNTTQDMSQINIRVSTEENIEQENAVFQFDANPYQSPADDDYLSISID
QTVFRVGDELYVVARTTASTPIDNLNLLFLSQGKVILAKSIDHMINNPERVFFSVSSDMVPMVRIIAYYINQLDQVVADS
IALKIENTCKHHVAINIKEETNEEGAYLPETPVTLLVDAYPTSYVGLLGVDKAVYALNNKHRLSRKKMFEMMQTYDIGCG
PGGGPTSPVIFKDSGLSVLTNALLAVPAREALTCQRVSSSRRKRSATQCQSNSRSRIEYCLNQLERRCNCDDNLTTTKMF
NRIQRWCTCETIASKLASKLPPYCPQATEQDIEDFSQCCELMNKWRIGSAPLGVDVLDSMDSISIGEDSTDTFEEFGMDV
RSDFRETWLFDLIRVGAPGRASLDLQTPGSITEWSLQAVSVTPTGGLCVTDPLDVNVFKSLSIQLQLPYSVVRSEQIEVL
ATIYNYNAQGATVRVSFYNPKGTCGESTNPSQPARRTVHVEGFNSQSLKFVIVPVEIGDLPITVTATSDVGSDGVQKILN
VIAHGVPQSVDHSVMLDPSGIYRQQRRSPRLRAAMMEDIQSDLLDTDNGVQYNILDLRPPENIIPGTESAVLSLIGNMLG
PILVDPVANYGEWLAYPRGCGEQTMSIVAPTIFVLKYLQTMKLMNDSLEEMAMDRISRGLASVLSHRREDGSFTIWGTNV
LYSSSTWLTSFVLKVFSHANTLTPVDENVTCKAAEWLVLNAQNPNGSFSELYKVHHTEMTGGISGEASMTAYVLIALYEG
HWCDGMHRDFPLALRNAQSFLERQVKYLSRPYAKAIVTYALALSRSAYASDSNRMLRNDAIILGDGSRYWTPNEADLTNE
DLPNWYRFRPSAIAIETTAYALLAQLELGDITYAGSIALWLSEQQNYEGGFISTQDSVLALQALTRYSEMANGGIDIDLS
CVVTSEVDESFHYEHRFLTHNALVKREVAVPVGGRLRSRCEGKGTAKLAVRMKFNRLPSSQDVCPFNVTYNAREARTGMD
PISISRSRVGIAPRSTTTSAQMARAKGDLVATIRFCARYTQNTRTNMGIIDVGLYSGFVLVSERLEDMVQTDHLHLVQRY
EVSQRSVIFYLDEIPADQDICMEFNARREIHVGNVQPVAIRVYDYYSPDKSCTSFYHPLQGNTQLPTLCNSADQCICPSE
RCALCTREPGKSLLDKACESSDNYALRVTMMSQERISGYTVYIGNVTRVVRTGQDDVSPGMLRHFYIKERCPCPRIKLNG
EHTIIGSAGLSFISDTGADGYKYLLDDRSIVEWWPTKLNKKKNLDIQTKLLNFEQDAQLCT
>XP_003730726.2 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 [Strongylocentrotus purpuratus | PB0082
MDGPVRGILMACIFFKFIISASPCPPRCQCDTNQMVSCAGSNQTVIPGDLQNSTRFLYLERNNIELIRENTFSSLHHLEE
LVLAQNKLYEIESGAFTGLSNLDKLFLEENSITILPPGIFAPLVRLTELHLGGNRFPVIPRNLFGSMPSLERLFVEGNQV
NLTIESEAFDGLGNLMELSLRSSRIQRLSHGMFSGLLNLARLDLSLNTFGSFTTDVRKDLQHLKGKRDSHTELTTLAEGT
FADLKSLVDLNMSSCSLKAINRNIFKGLTSLKQLYLSVNQLRGIDEGTFCESLNLVLLELDGNPLENLEAGSFRCLYRLG
YLNLNHTEFNRIGEGFFKELNELAVISLSSSGIVEIAGDAFQNKSRLTRIDLNDNGIKSFNTSLFDGTRNIRTLRLQNNQ
IKSLPEDIFNGVSGPLNLSLKGNPLVCDCQLDWIPGWLVRNGGTLDRCECDQPPALHGIHLDRVPYDDFHCTPYIVNDLP
HIYNATPGDKRFEIVCPVSGKPPPTITWTVPNGETMSKKTVPEYPNGLYRVRENDTLVIRDISSAVEGEFTCEARNNLGH
ISVQIEVQVVQISNSWMTAFLVVMIVLFVSCAICLLVTFLAPWRRRRRRRELTRTPARRVDPRYGPLSPIAEGNETDEL
>XP_030829869.1 SCO-spondin-like [Strongylocentrotus purpuratus | PB0083
MGHATYCLLLLTVVVFSIDADITHRRRPEYSLYTNNGNRTLIFDKLGRRSGSKAAFPRGKRSSSINQTITTTNNIPGIQV
PSIPEFGYCQVWAQQHYRSFDGKLFTFPGACTYILATDWPDFSFHIYVENDYSDCRQGNNSCSRSVLIDNGNPTSLIYLR
PGGIVTYKGAELTLPTKAGGLVLEQIADYILATSGLGFRILYDGKESITVYITTNTLLGNTAGLCGTYDMDPSNDFFMNT
GLQAEGAYNFGLSWKMTDEREPEHCPDVAAVSIPCTEKSFFESEADEERARVADQQCSQLLDDMFAACQQVVDPQPFVTA
CEEDVCACTTAHLHDETCKCASFSAYALECARRGVQVSWRSHYSCPYECPESSTKIYEQCGSTCRDVGCSAASSECEIDG
TVGCLEGCYCPPLTYKSLSGGCVSADQCSCSWQGSEYLPGRTISNGCNECTCVQGKWRCTQNECGGNCLVSGQGHYKTFD
NRYYDFAGTCSYILIKDCWNPFSIYLVSIENTACGMEGASCVKAVVIQDGALEIRLRRGSQVLINGEEVTQFPKMVGNFY
VNQPTHTQTAVIMPNGMTILFDGNNEVAVMADDRHVNSTCGLCGTYNNNHRDDFYTEAGDVEANPTSFANKWKLGSSCPD
ASYDTTPDPCDLYSQMALTATDECDRLLSDSAFAACRQHVDPQEYYDACRHDVCNCKGVDSCKCEVFAMYAAECTQKGII
IDWRASTPGCEMSCEDGTVYQPCHPMCDTTCIALSLDAACTETCVEGCACPGGYVLDPHGECVTREHCSCVDPDTGEFHT
NLKRIEKGCGYCQCLSGAWVCEGVDCPSDMCLTNQEYEPCASPCDMTCTNMHNFEDCPTLTCSGRCVCNLDTVWNGTSCI
APSSCPCHHGGQSYPEGHTIRTDDCHTCTCTNNRWECEEYLCYAACTTWGDPHFSSFDGRLFDFEGDCDYVLATDSVDEN
STNPFFRIIASNIPCGNTGITCTKAVTFTIGRGSSQEKLHLVRGKPVPASAGSFKITEVGNYVHVQTTIGVVLIWNGGTW
VQVKLKPDYKEKVGGLCGNYNDLINDDFMSPAGGLPETSALDFGDSWKVHNYCPLPEEPIFPCLRNPSRRAWAMRQCSVI
KSDVFKPCFSQVSYLPYYAKCVYDSCACDSGGDCECLCSAISAYAKECTAQGVPIKWRTNDLCPMQCDGCREYTPCIDLC
DTCSHQNDRDEQGNCPHTCFEGCSCPDGEFYHGDQCLETCPPGPPTGTPTPPTVTTPSTTTTTTPWVTTTTPTSTPFTTV
ESTTPWSETTTQPPVASTTPWPETTTQPPVVSTTPWPETTTQPPVVSTTPWPETTTQPPVVSTTPWPETTTQPPVVSTTP
WPETTTQPPVVSTTPWPETTTQPPVVSTTPWPETPTQPPVVSTTPWPETTTQPPVVSTTPWPETTTQPPIVSTTPWPETT
TQPPIVSTTPWPETTTQPPIVSTTPWPETTTQPPETTTAPPGSTTQPPETTTAPPGSTTQPPETTTAPPGSTTTEPGTTT
WGCREEVVCEWTPWCDDEAGGGKVTNTDEGEFEYIEDCRDQFDFCEEPTTLSAK

>NP_999674.1 alpha-1 collagen precursor [Strongylocentrotus purpuratus | PB0084
MYSFVDLAVCHRRKILLTLLVLFAVQSFSNGQAAGQYSEGPRGDKGQKGEPGDADINSANFPPGLPGPVGPPGPSGPSGP
AGNNGPPGPNGPRGNPGMDGLTGLPGIPGPPGPPGKSGSLVASAQTSSFNKGPSLAGYQYPQAQAAGTPGPRGPPGPPGS
RGPQGLTGPSGPSGETGPSGNSGPPGPSGLPGRPGSDGDDGTPGSQGQRGPAGTPGSRGTPGMPGAPGMKGHQGLPGMTG
SKGERGEGGERGSDGSPGPVGAPGPAGPSGQPGERGRTGPAGSQGDRGADGATGSQGPPGSTGPAGAPGMPGISGAKGDA
GSPGARGSPGLQGARGERGSEGSQGQTGPPGVPGRDGSNGAKGSAGPSGAQGTPGFPGARGPPGPAGSPGPAGSKGDQGN
PGQPGAQGESGPLGPRGETGPAGPPGAQGESGERGSRGALGPAGPPGGVGERGPMGPPGMSGAPGAPGAKGDRGLPGERG
SAGSKGSAGESGRPGEPGMPGQRGLTGPPGKQGRDGKPGPAGAPGEPGNSGPAGASGQRGLPGLVGLPGPQGQRGERGED
GGQGSPGAPGLTGEPGKRGEPGVAGPPGPQGSAGERGNQGPQGQAGSMGPPGPPGASGDAGAQGDNGPPGESGPEGPPGA
RGERGAPGERGPQGLTGAQGRRGIGGRAGNYGATGPPGQKGEMGPPGNVGLQGPPGELGPSGPPGARGPPGPSGSPGPDG
PAGAEGDRGPVGPMGPSGPSGMPGERGDNGEPGPGGAPGQRGDPGDLGPQGSPGSPGFAGPPGRSGNPGPQGELGPTGAR
GETGGPGPSGPTGDPGPQGPLGAPGQQGERGETGPQGQGGPPGPIGSLGAPGAQGPPGPTGPSGNAGSPGQPGARGEPGQ
SGSPGQPGLAGRTGPSGERGDKGNDGQSGPPGPPGPAGPAGQSGILGLAGGSGPRGPGGPAGPPGAAGSRGPAGKSGDRG
SPGAVGPAGNPGPAGENGMPGSDGNDGAPGPQGSRGEKGDTGASGANGSPGAPGPIGAPGAAGASGPRGETGSTGAPGPL
GPTGARGSTGPAGPSGPSGPAGERGETGPAGHKGHPGVSGLPGLQGTSGPMGEPGAPGEQGQQGTRGLPGARGSNGNDGP
SGPRGFDGPEGPRGPRGEGGSSGPPGPPGPPGPPGPPGQVQSSYGVRYPSFQSGGKGQGSSPYGYAYRDDSKNDAVKIQD
TELLGAISALGQQIELIKAPQGKAKTNPARSCKDVFLNNVEAESGYYWVDPNLGCQKDAIQVYCEAETGATCVPSTNNVV
SNMTWYVGKTKRAFFSSMHGGDKFAYIEDSTQMTFLRLLSTSARQTVTYFCKNVQGNPIFLSSSDVELVDDQDSKFNYRT
LEDGCSSSSSQWGKSVYEYETKKTTRLPIVDFAPGEVGSESQMFGLEMGPVCFS
>XP_030838572.1 collagen alpha-1(XXII) chain isoform X1 [Strongylocentrotus purpuratus | PB0091
MMELRKVLCSLRRGIVFISICTLFRINHIKAQLTETVECPGDIRLEENDLPGWDIIRMFELDSATIQGVRVVTGSDDVQR
AYRLLKNHDISEPASNQFPQGLPDEFSFVSTFKLTDRTGDDEDWWLWLIRDRAGTPQIGIRLMGEEKALQFIYVNELGQL
ENVRFDNAMMLFDRNWHKLHMAVSKNRLDLFVDCLSIGSVALRTRGQVDTLGETLIGRKFSAGGGPVQFILQWMIIHCDR
TFPTRDHCSEISISEATEEPKTCSTICPEGPAGRQGDPGLPGPAGQMGRPGIPGRIGSTGTKGEKGSEGYRGQPGPIGPV
GNPGPRGSPGPGGLNGDPGRAGLKGEMGSNGLPGLPGVPGDQGPRGYTGQQGDQGRPGDTPTREQLIDIVVSIPGLQGDP
GQRGLPGIDGVKGEKGTRGEYGYRGVEGPKGIRGETGLRGNLGEPGPPGPPGTLGDISIMEIVGGGETQLIPGPAGSPGI
PGIPGDPGIQGFQGDQGERGIKGLSGIKGEKGSGGLRGPRGDTGSAGEAGPMGPPGPRGDKGSAGPQGPQGLFGPEGERG
PAGLAGPRGGSGPQGESGPRGYKGATGSLGFPGFKGDKGSFGDLGLPGLSGPKGEKGGKGSNGLRGIAGVPGTNGNPGPI
GDQGEQGVQGNKGQPGLRGVRGEKGDEGLPGPMGLTGLRGTKGDIGNTGYTGLPGKDGDSGPRGPQGRQGIKGALGEDGG
RGPVGLIGIPGRRGSKGEIGANGKTGPGGRNGKDGQTGPMGPRGPKGERGDNGDPGSTGPQGPRGTQGYGGGRGEKGNKG
DRGIGGTNGQNGIPGLTPSKDEILRLIERYFQNNIESFEQRFRGPPGPPGESIQGEPGPAGILGLSGPTGPMGLSGNPGS
MGRPGMLGGVGTPGERGPRGSRGQKGDRGQGYTGPTGAPGERGLPGKPGIGRPGKDGQPGFPGPAGLPGERGESGQVGDP
GFCEYCNYAPGTYPFQIPPAIDLNNKG
>XP_030842761.1 alkaline phosphatase [Strongylocentrotus purpuratus | PB0092
MTPYLLLPLFLSALLSLATSQDAAFWNNQAQRTLEEALNLRQNQGIAKNVIFFLGDGMDITTTTAARILRGQMDGETGEE
GSLAWDDFPHVALSKTYNTDQQVADSAGTATAFLCGVKAKAGTLGIDDGAERGSCASVAGTEVDSVLVEANRAGKATGLI
STARVTHATPAAAYAHSAERDWENNDRVPDEEADEGCIDIARQLVEENNFINLILGGGRVNFLPNTTLDPEYGDENTTGY
RTDGLNLIEQWLSVKGSSAQYVWNKTALDRVDLSSTEYLLGLFEPSHMKYEVDRLNDTAGEPSIAEMTELAINMLSSDED
GFFLMVESGRIDHGHHMGVAHKALTDTIAFHEAVAKAIEMTDSDDTLILVTADHGHAFAIGGYASRGNPIFGYDDRNNGS
DDKPYLTLSYANGPGGIALADSYINTGARPNHYTSDYDSEGFVQDATVPAISETHGGADVAIYAHGPWSHLFHGTHEQNY
IPHVVRYAACYSDSEDNACTRATEEPPMCTGSAHPTVLARCASVILPLISLIFLWISM
>XP_030828711.1 inter-alpha-trypsin inhibitor heavy chain H3 [Strongylocentrotus purpuratus | PB0093
MNKGVVVVAFVLAFIGTSTCLPTGLLNHAELGDMTAVLLPQIQRAEYGYGDDEILDREERGLSPSGSGSGPLSGPLSGLT
DDEDLVTESPQLATKPEVVRLAVLSKIMSRFASTEVRSKLKNLAWKAAEAKFTISLPEDAFISAFSMTIDDIVYHSEVKP
KDVAQREYNEAKAKGQTAGQVKQSSPDENKFTVSVTVEARTSVLFNLTYEQLLKRKNGLFEQRISIQPGQMVPDIRVEAR
LTEPQGLKEVNASWAVADKSDEAKLNDMTLVDLKVRSAKVLFASKGEGLLTTSNGIMGDFIIKYDVMHDVKAGHLQIVNG
YFVHYFSPVGLPKTRKNVVFVIDVSGSMRGRKIDQTKRAFTTILDDVRPIDRINIVLFESDVRVWRSNQMVEATSDNIAA
AKRHVNRIRAGGGTNLYDGLRNAVDLLMEHGNGEAMPLIIMLTDGQPTSGSVKSTSEIIQRITNLIDGRLSLFSVSFGNG
VDFSFLEKLSLSNQALARKVYEDSSASLQMKGFYDEVANPLLFNINLEYSHGLVDEDSLTQSNFMAYFDGTEITVAGKLK
DDVIYAVWNSSNETILPTAQHPGTISIGDGNEGGSYVYGDLSVFITGQSLDVDIMFNTSTPIEREHPLRRHEVDDFAQRL
WAYLTIKKLLDQRKTVDDRETKAALSERALNLSLKYHFVTPLTSLLVVKPDVNDTDIHGDGELEVLSADMQSQSSSNIAL
QSVPRPRPKGTSGVSLRTKPQFIPPLSRQSIPQSVPNPAPVVSSFRPQFIRPLSRQSIPQSVPKPPPVASSFCE
>XP_030854391.1 uncharacterized protein LOC584702 [Strongylocentrotus purpuratus | PB0095
MAKTSDPEKKCENAPPDGVVKEGPEETAHGWPCLISLKRSSPWEEKESQKDSPGLKEKSEEIAASEQNTSKGKDRSLLPC
SNKKRKTCTTRLAGIEPKYIWMPLLIPVLFIFIPGADGLKVQRRDFRKIIIGMNEVKMVTDPILRPVDDSVYSVFAKDGN
DDHEGFECTPGFVSTNPSCIIVVGDTSKAECEGLQISGNASYLAVVGSELTHDRTTYCIYQQVPKFFILYTLEVSKKREQ
DINDCASYPCQNGGACLDGLDSYTCNCAKGYDGANCESDINECAPNPCQNGGACVDGLDSYTCNCAKGYGGANCEIAPET
NHYKVAFYILLGIDVFILLVIAIVIKKNFPCIRAWWKKYIMKQESTDHIEGGSPSPTVGTPMLPITVAHEHRDE
>XP_030829688.1 von Willebrand factor D and EGF domain-containing protein isoform X1 [Strongylocentrotus purpuratus | PB0097
MDNMVGVGMRQVSGHCQTVMPGVRAQREVASTWKHALLLVLVMAGTVYSAMAQTECSPEEHRILDSPFRSVEYAASAMTT
KLCDKSIERGWYRFTIYGKSAELPTECVQVNQCGTEAPIWLDTKGDSLPPPGESARHAACVSWTPSTTQACCFFSFPVTV
TNCGDFFVYLLQPARGCNMAYCAKEARRKCGPGEISPDGFEPCRESFPAILGLPEITPTHFEDVVELRCSFRGLESRQGS
NKGYTVTWFKAGPEEMYQQLSKNDTIENFASLELRKHFSLGDKVICTVQAFFNATRQLKSPPIESDPFHITISVSPRRLE
IAEDGQRHLVAFESTVPIHCEDPQQSCSVLIPLSTISNDATVGYDIALSECFVELRPRSCGISEARCRQAFMFVTAVTDF
QHDGRTTNEIITGNVVSSDPFWRGFNPDDLEVIVNDIPTAQCYSFTDPHFITFDRKKYDYYKTGTFVLYKSLSREFEVHT
RIWNCGGISEQVSCNCGFVAKEDNDVISVDMCDGNVLETRAEVRVRSPQPLTDGVKIKQAKNGTKITVEFSSGAFIRADI
SDWGMSITVQAPSLDFNRTVGLCGTFDGNPENEFHDKQGRNLALAMRYGQANEFVELWRLRDGGMFNMIPLPVPYQLRLP
ACSCLSPIVPSSSDLYPIQSIGCGLGGTSCRTRCTRFEDVHRRELVQSSDVTSMYSNIVSNNPFGRRRKRSASRDKVTDR
TKRQSNSESSLDPTSLLDFFNLFDLDIPVGLIDQTMSVGPSVQNTYFFLPDHKTSDLRPLKATWPTPSGISLEQAREFCF
QTVGNTTLASACGESGLWTNMYIDDAVEMCLSDVQLTEDLTWASQTLPLVENQCEAAYVSNRTLWRPDHSAGNELGEVVP
PEGVLRALNCPNECNGHGVCTKQGCICEDKYEPPDCSWKDDAIPYIVRLENNGLCDRETQRCDMVRITAREYREGKTVTC
LFSLSKDGLNDVSSVIYAQSIAIRINRKTVLCNVPTIEGAANEDGTMRWEVQVMYSDSSPSNTMTLIHYDSKCHVCTWTG
ACTTKDNACVIESRCYSAGQHNERDSCQQCRPLVSRHEWSISEDNVPPVLGVDTQFTTVTGRAFTHQLDAIDPDSTTGGG
VEFSVQSLVPNDLYHVNISRFGHLYWLSNVEGDYTVPVRLTDECESSVTFEMEITVLACRCLNGGDCILDSPSGVLTNNL
PYSCSCPSPYTGEFCDINMAPGIGSCESNPCMHGQCRDNMFGFTCECENGYTGLTCSIMKNVCDNSPCFEGVACTVRGLG
SFSCGNCPEGYYGDGIVCKASKCKVTCPKNMVCDPNVGCVCKEGYHGYACFRPVCNPPCLNNGRCVQPDTCACPVGYTGQ
YCQRGQCDPACLNNGRCMSHNRCHCWPGFTGPRCEIMSCRLNCMNGGYCVTPDRCICRDGYTGPTCQTPVCSPMCRNGGR
CVRPGLCVCPRGFQGQYCQRAMCTLPCRNGGTCVRKDMCSCPKGYTGRRCERAICEPRCQNGGRCVSPGRCSCPSGYRGR
KCHKAICPSGCRNGGECVQPNVCMCKPGHTGSSCETSVCHKPCMYGGKCIKPDTCLCRRGYRGDQCENNRLLHRRYRRDE
EDLL
>XP_783262.3 leucine-rich repeat-containing protein 15 [Strongylocentrotus purpuratus | PB0098
MVDPTLILMETLVLLFYLDDSKAVVQECSDVCDFDEWGKEAECQGRALESVPQGCLHAKTLQMQDNRLAKLAQGSFRNFT
CLKYLYLERNNMTVEVGAFEGCSRLEKVHLNQNHLPILTKGILDGMPRVLYMFLNNASVHEIQPRAFGNMSQLKFLSLED
NRLNTPPCDAFSIDSSLETLYLTGNNISYLPNNCFSGFSRLTKLYLKRNPLVNPNLFAFKGLESLTVLDLQFTNLTEVPT
GIFQNAINIEKLYLSFNNISHLSNRDFMSLYRLTNLYLQHNNLIVIQEQSFEFLSALHTLDLSFNRISSIRENALSHLSN
IRDIKLQNNLLTSTRNISFNTLPNETKVNFTHNPLHCDCFLEPFLAWSKASSTNVLDGSLDTSHNARCSSPPVFKGRLVL
GIRRDDICPEEPGVSFESHTVSAPDMEREERVDLSKTSAFPATVVTVIAVVVILIIVVVIVSVALLRRRKQNIRKRQRHD
LETNIQITTNPLDTAILRGHRQITSPSPPSLIPVDDPYYISINDESPCQSPVHPPLHHPMPPRFSSQSNMNQDGIIYSSV
LPDGDPQRTTDNDVTYTSVQHDDTDSGPVTRPLSMMNEMPIEEWMRKNCRLDSGTSPSGTTHNSETKLTGNAGSPYITMI
THT
>XP_030856413.1 cathepsin L1-like [Strongylocentrotus purpuratus | PB0100
MSNLTFLVAMGLVACAAAAFVKPTSPDLDSRWLEWKIAHTKSYTNDMNELERRLVWEENVKMINMHNLDHSLHKKGFRLG
MNEYGDMRLHEVRSTMNGYKSSNVTKVQGSTFLTPSNIQVPDTVDWRTKGYVTPVKNQGQCGSCWAFSTTGSLEGQTFKK
TSKLVSLSEQNLVDCSRTEGNMGCEGGLMDQGFQYVIDNHGIDSEDCYPYDAEDETCHYKASCDSAEVTGFTDVTSGDEQ
ALMEAVASVGPVSVAIDASHQSFQLYESGVYDEPECSSSELDHGVLVVGYGTDGGKDYWLVKNSWGETWGLSGYIKMSRN
KSNQCGIATSASYPLV
>XP_786004.2 meteorin-like protein [Strongylocentrotus purpuratus | PB0103
MLHDVRPREDNRLGDAANGGCCTMENCNGKSRWIIQKLLAIATTLLLFSSSAHGLENDLCNWTGSGLEIDAGERSIQQLN
INCQSGHISWSYPRNALHITFSNGKSKEHFRLCLNIKIRGNGANIYRETPGKLMPLLLDDRPEFERNTFGKEVHVHDILE
RIQYERTSPKEEHCFAAKDGKAIIYIEAAPNPLSIKYETTIDYRIEELPLFRNPIHHVRKECRKCEGGEIVAAFCSSDFA
IKGRMLAVTPEESTRETYINVAAGMVYRQRDPVFLPGKHSRYYGLITTPTRCGVKKLEGHYLMTGQIVLGRAQLGCMAHL
SVVKKVAREVDEAGISPCDLTPILGHNHHRYIE
>XP_030855712.1 alpha-1 collagen isoform X3 [Strongylocentrotus purpuratus | PB0104
MYSFVDLAVCHRRKILLTLLVLFAVQSFSNGQAVTITNLDVMLSNPAPISEGQVNSVPVDVNIDLLNRKTQDVSGTGLWK
LQVWGSLRADGVGQQISLSEQALTRNQEATPVERGAPFFFRNVPYELDMRGVSCSEINYVCVRIRKGNDPDPQFTFKGKP
NQATTFSDCAPISECSGVQLRGLTWELQASNVIAGMRNPLNITAQVNFVEGAGDVSGENLWRLGLYGSRNAQGSGEKFNY
VRQTLNEFESAYPLRGAGDINFRFARAAFDLAAIGCTDYDYMCGEFTKADNPNPDFSFSVYPSGMTKITCKGWPCRAVVN
IEAVSAIPVRGSLVAGRADNPIEMYVKVNGSGVGVAGQNLWTLSSYGSQNSRGAGRKYAQTMQILTPEQQNTMLVPGTPM
ELGRVSMNIDMTNQDCNQVTHVCLTLGKGQNPTTVFSVVPVPNSNVLTKCIPYQCAVATARSLSWDYDAPTVVLGQQSDL
TINTEVSFVDNEASVVGSNLWKLGIFGSRNLNGRGQRIGEKRQILRTNEASTPLDPRTADGLHRLNINNIRTTFDMSSIG
CGAFPYLCVEFGQADRPRPSFEFATEDGTDSVVNCKLLQCENDVMLNELHLTLENGRILDARPENPLTFSLEGSLIGPGV
QGRDLWTVSMFGSGEPDGVGPRFGQMDQILDTRQRNKPYVPNENLDFGNIDLNFDMSSHECARIRYMCVEFSKNDQTSVP
FTLTASSGEAWISCVDIPCEGVIASDLIWHYQAPEGITLGAPIPILLDAVVEFSSVSADVIGRNLWALTLYGNTMESGRG
DIIGILEGNILGNKAASRNLLVGDDSLNFTNVRSEKDLSRIGCLHEGYLCLTFGRGANPKPPFMLLTTSGGDSIVSCKKV
PCPRNVELTNIDTGFVSGSLIEGTPSNEIVLSMTANSAPNSNGINGISLWSVGAWGSRNPDGSGKRINPVEGEVLSGAQS
SINLTPGGMIDFGEVAIDYSMEDVTCRDINYICVELDKNSGSNVEFNLIAERETMRRCEAVSCSGVLARTLSWDFRANEV
RPNQRSPITVQASVRFDENSSPLTGSRLWRMSLFGSDNLDGNGRTFDPIHQILDAQNQRKSLNPQFPLTFNNVPTEYNVG
AIGCGEYQFLCMEFTRADNSDPAFVFDVVGGGNKLVNCKQLLCNSDVVLQGMTTNIVGSPIVTEGIRNTVDIDTSVFSSP
ESRPLDSSPGLWQLSAYLTPSPDSPLQFNVQNQVLSRQQASSALNPGSPIGFGPVSVNVDLRQTTCEQAGYVCTRLSKGP
SPRVDFNLQIVPDPSAVKSCERIECNGVHLQNNIDWTYNADDSIPGRETPISITTNLLPFPNSRDITGNDLWEMGLYGSK
NPDGSGEKFNYEDQILSPEQAGTPLDGDTPFFLDNIDTNFDVGSVGCTDFRYLCVDFKKGRNPSTDFTFQIGDTAENTIT
SCKRMACDSNAIVSDLVSTLGSDAILIEGNPRNGLAVDLRAITSLESTPILGDRLWQVDSFLSRNPDGSGREGALNTNIL
DPLQSAWPLRPGIDIDYGQVLVDVNMQDVSCAEARYMCFRLRRNADATVSFNLQGEPDDSVLTSCLDMTQQCQGVILTGI
DWSYDESVPRTLSISASADVTLNSRNLDGSGLWTMGLFGSTNGRGLGNRLGHQQQILNLYNQGRTVMPPRPITFRNIDTR
FNIEQLGCNSQYQYLCLELSKGANPNPEFSFRTIDGDDSLMSCKQRECRAVIITGQETTPSAFRLREGEPVNEINLATVV
STAREGGTVTGDQLWRLGFYGSTNPDGTGQRVGYQEQILPYYHADQDLERPGDTIDFSGLNANFDMTSIPCSQVQYLCTV
LSKNPEASDDFTLTTQPNEDVLTSCFPVPSGACRGVIVTDMEWSYTSSKPIPSQPDVLEIDMSVDSLETASGIDGRRMWR
VGIFASKRRDGTGPRQGTNYQILNTFQARKPLVAGQRLNIDTIATRFDLDEINCDSGYRYLCLEFAKSMRPLPDFEFTTT
TGGNTIIRCKEYECDRGVKLMDLETIPDTNYQTVISQKRENILQFDMMAAPASDTAALRGVNLWELALWGSDNPIGEGPR
HNERTAYNLNTYQKSVAVTNQDVLRFGTVETTFDMTGLTCDEVQYICARLQKSSDAVPNFQLSGVPNNRVLTQCFNVRCA
GVVVDNTRLSVSSSSLTDGSDEVFFSVTMNSQDQSADAALENMWQMSAYLTSTSDGTGKRVVLGEEILTPRESSQALFSG
SRTGFYDMRTRVNRDTLDCTASNYLCIEVTRASNAPNTFSFTGSQANSLSSCERLECAKKPAGQYSEGPRGDKGQKGEPG
DADINSANFPPGLPGPVGPPGPSGPSGPAGNNGPPGPNGPRGNPGMDGLTGLPGIPGPPGPPGKSGSLVASAQTSSFNKG
PSLAGYQYPQAQAAGTPGPRGPPGPPGSRGPQGLTGPSGPSGETGPSGNSGPPGPSGLPGRPGSDGDDGTPGSQGQRGPA
GTPGSRGTPGMPGAPGMKGHQGLPGMTGSKGERGEGGERGSDGSPGPVGAPGPAGPSGQPGERGRTGPAGSQGDRGADGA
TGSQGPPGSTGPAGAPGMPGISGAKGDAGSPGARGSPGLQGARGERGSEGSQGQTGPPGVPGRDGSNGAKGSAGPSGAQG
TPGFPGARGPPGPAGSPGPAGSKGDQGNPGQPGAQGESGPLGPRGETGPAGPPGAQGESGERGSRGSVGPAGPPGGVGER
GPMGPPGMSGAPGAPGAKGDRGLPGERGSAGSKGSAGESGRPGEPGMPGQRGLTGPPGKQGRDGKPGPAGAPGEPGNSGP
AGASGQRGLPGLVGLPGPQGQRGERGEDGGQGSPGAPGLTGEPGKRGEPGVAGPPGPQGSAGERGNQGPQGQAGSMGPPG
PPGASGDAGAQGDNGPPGESGPQGPPGARGERGAPGERGPQGLTGAQGRRGIGGRAGNDGATGPPGQKGEMGPPGNVGLQ
GPPGELGPSGPPGARGPPGPSGSPGPDGPAGAEGDRGPVGPMGPSGPSGMPGERGDNGEPGPGGAPGQRGDPGDQGPQGS
PGSPGFAGPPGEAGSRGPAGKSGDRGSPGAVGPAGNPGPAGENGMPGSDGNDGAPGPQGSRGEKGDTGASGANGSPGAPG
PIGAPGAAGASGPRGETGSTGAPGPQGPTGARGSTGPAGPSGPSGPAGERGETGPAGHKGHPGVSGLPGLQGTSGPMGEP
GAPGEQGQQGTRGLPGARGSNGNDGPSGPRGFDGPEGPRGPRGEGGSSGPPGPPGPPGPPGPPGQVQSSYGVRYPSFQSG
GKGQGSSPYGYAYRDDSKNDAVKIQDTELLGAISALGQQIELIKAPQGKAKTNPARSCKDVFLNNVEAESGYYWVDPNLG
CQKDAIQVYCEAETGATCVPSTNNVVSNMTWYVGKTKRAFFSSMHGGDKFAYIEDSTQMTFLRLLSTSARQTVTYFCKNV
QGNPIFLSSSDVELVDDQDSKFNYRTLEDGCSSSSSQWGKSVYEYETKKTTRLPIVDFAPGEVGSESQMFGLEMGPVCFS
>XP_030828530.1 laminin subunit beta-1 [Strongylocentrotus purpuratus | PB0105
MIMAEDLTALYIVLFLSAVASYGQLILAGSGACEGDSCYAGDLLIGREDKLFASSTCGLNGREPFYIVSHLENRNREIFH
CDSRTPWQEGVNDLNHEIKHVVTSMDNSQKKVRWWQSENGLEQVYIQFDLEAVFHFTHLIMTFKSFRPKAMVIERSSDFG
HTWKPYRYFAYDCAGSFPEVSRAPIRNISQVICESRYSAVEPSTGGEVIFRVLPPNIPIEDPYSREVQDMIKVTNIRINI
TELHFLGDHLFDDGDEVFNKYYYALYEMVVRGSCHCFNHASRCVPADGMEFKQQMVNGQCECIHNTEGKNCERCEPFFND
QPWRPAGLRGENNECKRCNCNDHATSCHFDEAVYRLTNGASGGVCDNCLHNTVGRNCEQCKPFFFMHPDRDIRDPNICVP
CNCDPAGSENGGECASHTQGEMVAGMCLCKRYVTGQRCDTCQDGYWELNEANPEGCRECACDLLGSENNMGCDKSTGNCR
CKRYVTGQNCDRCYEGYYGLSADLYGCKQCECDPGGSYNNSCNQASGQCPCRRNIGERQCGQVNSGYFYVNMDYYTYEAE
YARAVGDLSLVDYYPRMRESEYIGWTGPGFMRVHEGGGIEFTVSNLPMSGNYDLILRYEPLLPGVWEDVRITINRPGDIP
TQSVCGNTIPQDDLLVTTLPSGSRHVVLSNPVCLETGKTYTIRVDFTRYSSDNQDSNAQILLDSLVVMPRATIYPIFQGP
DPIEQYRREQWDYYRCGEAHMSAVHSPLSDICKELMFSMSALAFDGALPCQCDPTGSLSNMCDETGGQCQCKPNVIGRTC
NQCAPGTYGFGPEGCTPCDCDGTGSLNEFCNQLTGQCPCRPNTYGQQCNECQPGFWNFPNCQRCNCNGHADICDPRTGEC
IDCQSNTAGFECESCKRGYYGDPTRGSALPCQACLCPGGAGSGNQFAESCQLDQATQTVQCDCFSGYTGIRCDQCDNNYF
GNPTEARGVCNLCSCNGNTLSSTPGNCDARSGKCLQCLYNTDGFNCEQCAPGFYGDAIQRTCRDCQCNVLGTDRSQCDLD
NNCGVCDPVSGQCPCLPNVLGQQCDRCAQDHWKLASGTGCEACNCCPYGAVSSRCDEFTGQCACRSGFGGRECCDCEANF
WGDPRDGCYECDCDEQGSATSQCERATGQCVCLPGVTGYRCDQCARGTTGELPRCEPCGECFDDWDLTILHLRNETYDLI
ARARNIKVSGVSGVYDREFSRLEGLVDYAESLIRGAPSVTETDVDNIQSELDDIRATLEEYRQQVQGLEDMQRRTRGNIA
RANRELDLLEREGDELQADAERLQRESYDFGTANVEGAMNSILRSQNLSRAAEGRVDDTQPTLDQSAAVRQEVEDLIGER
NAALESERQGYLDRLDDVDNQLTGLEGLLAGLNEEICGSPGDSCDICGGAGCGQCGGLGCGGSVQKAEDALRRATEADQK
LDQKEEEARSMLDEMMQAKDRTGEAQDLAQQAYDQALLAKQEAEQGQINIKDLINNITDFLGRSKSEPDDIRLLVNETLN
TKISLSPEEIEDLAEQIEDIIATLENIDEIIAATRDDLQRVNDLKARADAAREYAEGVLDSAEDVVRALNQAEAAQNIAD
NAINNATEDIEDAGDSLTSIESEARDAKDKSNNLLDKIEAMKAQLEGVQLKVTDNQEKVTQAVDLAEMAEGQALDVAGRV
EEMERDFNQTSDEVMAKVAEVEGAKGRADTLFLNVIAFEEKITKDYEDLQEMETTFNNNNATLHDLTAEIAALNMKMMQI
LMDIQTKAAYYRSCTESPTAP
>XP_030840642.1 matrix metalloproteinase-24 isoform X1 [Strongylocentrotus purpuratus | PB0107
MDTALLLLVLLNLIALTFPAAIPPRIPRFLKDRLQITHKEYSYLIRNGYLRPRNYEFTFEAEKDIPVVTDAISRFQEFYK
LPVTGELDERTRGVMWEPRCGYPDVGESLHNETVENRAGHHRVRRYDIADGRYKWDSSQITYSLVNFPTRGGIKLSDLRN
TIKRAFEVWSDVTPLVFTELHGHEVNQAMVRIAFMKGRHSHDLEHPIFDGPNGDLAHAFSPKSGWGEVNGDIHFDDDDVF
TLGNNDRGYNFFQTAAHEIGHALGLDHSNDPEALMWPHYHFMRDFELPDDDIRGVQALYGPNPNPPKRKRKSRKHSKKRT
KTSPRVPNVRIDQGPRPKSTLVRQPSKKSYCTSGYSAVTSISGSIYTFKGKFYWRSWRRLLVTPKDGRKIHDKWYHLPAN
IRASYQRRDGKTVFFRGAKYWVYFGSQMEPGYPRPVAELGLPKGVDAALSKTKAKTFFFKGDQVWRFDERKKSVDNGYPK
KIGEVFTGLGDKVTAAFQHDDGNSYLLRGKKYYRVAKGKYEVDPGYPRHFTSDFLGCASVTA
>XP_030855692.1 thrombospondin-1 [Strongylocentrotus purpuratus | PB0108
MEKIRCFSCFVLFIATLLPAIIAQSSYVEFNVLQDVGISAASPGVDLVRGQEENSVAYKIKPNKGDMAANTIDVQRLGDA
MNDEDGFVLVAKVKMGQKARGTVVSLDGHGHTDRLFGLVIDRKSDSVLMPYSYRRDGVTTQDSLEFSGLNLEDTEDRDWH
TFTLDIQGNLAILYADCTRVGLQIMYGSFVYDVTPDQYSLRLGKGLKGRKDVPDFKGIIEDVKFIFGQRGTRILRLQGCD
IEASSSQSSSSDISPDFGGQSHDSQLSPFGGGHESIPDVGVGVGVGVGVGVGVGVGPLVSQPNIHPSVHEVETPEQETIA
PVPPKMPEVPTVPNTPHTAIEPGVVEGPLNDGSPMNYNLPSLYLPNSPGSHNFAEPTNGARPMPNMNDVIPNGQCAITCD
QISQLRNMVDVLSQGQENILTRVTDMDNRIPSQTPPWLDGCFYKNEIRQNFEEWKDDACTTCECNAPAVTCRLIECQPIT
CQNPIIKPGECCPQCPNEEQGWSDWTEWTSCSVTCGSGTMQRGRSCDRMRYPCNGRSVETRNCIRDSCVSVVDGGWSNWT
PWACGITCGVGTETRVRSCNSPPPQNGGARCLGEAFGAGREERLCQRDPCPVDGAWGEWSLWTACTHSCDGGNQERYRFC
DSPTPAHGGRNCSGIKRQEQMCNQRPCPIDGCLSSPCFEGVDCRSSDDGVFQCGPCPVGFRGDGQSCTDVNECLEVLNTC
FHHHSQHRCINKIPGYSCQECPTGYRGNQPNGIGIFHASRYRQQCIPINPCTEGTHDCAPDAKCTFFGPYSQPQYGCRCR
TGYAGDGYACGLDSDLDGRPDVDLDCQGLGDYMHCHKDNCPRLPNSGQEDSDRDGEGDACDDDDDDDGIRDDRDNCQFTP
NRWQGDRDRDKVGDECDNCPTHSNPRQENVDGDEFGDECDDDIDNDGHDNFIDNCPKHANANQDDSDHDGLGDLCDNCPF
DFNPLQIDTDDDNVGDECDTDEDVDGDGHQDNLDNCPDIPNASQKDHDNDGIGDACDPDDDNDGVTDADDNCRLVFNPSQ
NDTDENGRGDACESDFDGDGVADIMDACPENSMIQRTDLSAFQMVPMDPSGASQLEPNWMVRNHGLELVQTINSDPGLAV
GYDEFESVEFSGTFYVNTAKDDDYAGFIFGYQSNHRFYAVMWKQVTQKYWQPDPSPAEATAGLQLKLINSTTGPGEYLRN
AMWHTGDTENQVKLIWSDPNKIGWKDFTAYRWTVQHRPIDGFMQVTAWEGSNVLADSGPLYDSTLRGGRLGLYCFSQEMV
FFSDMEYRCLSDY
>XP_030844513.1 trypsin-2 [Strongylocentrotus purpuratus | PB0110
MLKAIVLLSCVAAALADCGKPAVDPVNTFIVGGDAAMPGSWPWQVGIRKNYLVGQGGYHMCGATLIDNQWIVSAAHCFYR
WKRLSDYTITLGSHDRDEVDSTQVNAKLGGIFVHEDYNSMTLDNDIAMLKLETPIDFNDAISEACVATSDYPADTMCVVT
GWGDQEAAIDNAELQQVYVPIIDTKVCNRPSWYNGEITDNMFCAGYSSGGMDSCQGDSGGPFVCKNSAGAWELTGVVSWG
YGCADPLNPGVYTRVTQYNDWISGIKRNN
>XP_030833291.1 fibrillin-1 isoform X3 [Strongylocentrotus purpuratus | PB0111
MLRSSLLVLLVCLSTVVVAQSNVINGPNVCGMRFYSYCCPGWRLHPRTKQCVVPVCNRPCGSGYCQRPNSCSCPGGQISV
SGCDGYSGGNPCTTQCLNGGSCQGNSCNCPNGFSGTNCGMPTCNPPCQNGGECSGGNRCSCPPGFGGSQCQTDYRTGVCY
LQSTSNGYCSAGVEGLHCTKALCCATIGQGWGDPCENCDTFDNPCDRGYILNGRTGQCIDADECLMIPGLCDGGQCTNTQ
GSYACQCPAGFELSMSTLSCVDMNECQTGYLCQNGRCINTQGSFRCDCNPGYFLGQDGHHCTDIDTPNTPVTPEEIGYCY
MRFRNRNSRGTSCSQELAVRMSFLDCCCSVDHAEGWGLSRSDCSPCRTENEELYRRLCEGVGELTTPQPRRTPNPQTRTD
GPGVVTLTPPTVTPPRKITPRPEGICLMVPNICRNGLCVSLGGVMEYRCECFEGYENAGRYTCQDINECRDRSLCRYGAC
ENTDGSFRCVCPSGYKLSLDQRSCEDVDECRTNPNVCHHGTCMNIVGSHTCDCFEGYQKSIDGRYCIDVDECTLGSHRCR
NAECENLPGTYECICTEGYEAIGSSGVCIDVNECAQETNPCPLGFCINTLGGYQCQCPVGYATGQDGTCVENRRGFCFLD
GDLGRCTHQSMGQMTISSCCCSAVLLQEALSWGPNCESCPPQGTLQFEQLCKHGTGWTSQRININECTLFNNLCDNGVCE
DLTGNYKCRCNSGFQPQADGKECIDENECSYNRLLCHNGACRNTPGSFVCECPDGYELDARSSVCQDVNECQNPSLCNNG
RCINTRGSYRCECIYPGTELDPTGTICVDNRIATCWTRISNGQCEADIMGPMRRDECCSTFGRAWGSPCEACPLAFGDCP
RGFSEINSECVDLNECELNPMVCNNGLCENTMGSYRCVCEEGLTLDTSGRNCVDLRSYECFLDYSEGQCSSPIPGLYRNS
VCCCSLGYSYGDQGRCYECPQEGSVEFDVLCPRGRGFADTRPRPDLLDGTVYINDINECNAYDGICKYGECTNIIGSYDC
VCDVGFAMDEFGYQCVDIDECRITFGACGNGSCENTPGDFRCNCYEGFEAHPVMRSCMDINECETVPGLCRGGSCTNLPG
MFRCDCPLGQELTPDGQACRDINECSISTGICSNGECHNIVGTYRCMCNPGFRPTANYRACEDMNECDMDNGGCDHNCVN
SQGSYECQCQSGYSLRVNGRTCVDIDECADNPDICGGGQCENQEGGYLCDCFVGFRPADDFRSCLDIDECSTDAGVCVAG
VCKNTRGSFTCQCFEGYSMKPGIPGCSDIDECMLQMHQCAINSQCENTIGSFQCRCNPGFIVDENANICIDVDECESSNH
DCHEDARCVNIPGSYQCQCNQGFIGDGLSCIDVDECMQNQALCVNGQCINNPGGYVCECEMGFYPTERRDSCEDIDECSN
FPDICVFGQCINVPGTFRCECNPGYMLDIGGGNCTDVNECEDPGTYCVSGLCTNSMGSYVCECPPNWVLSRDGTTCADVR
TGLCYAHGPGAESRLDVNECSLLLGTSIPRTKCCCSELGKGWGDPCELCPLVNTTEFFLLCPYGIGVHIDPNATRPVNEI
NQCRDFPNICRGGECQQVEGSFRCVCPTGYEYDFEQMMCIDIDECFEGMHRCVGNSICRNTPGNHECICPPGYQLSVSRL
SCDDINECLTRPGTCINGQCTNQIGSFVCVCDQGFQLSADGTQCNDIDECFRFPDRCGNGTCQNVVGDFACSCNRGFELT
INGDCADINECATMQGTCPNGRCVNTPGSFFCDCVEGYVLSLSGLRCEDENECISRLNICQNGRCDNTIGSFRCSCFDGF
QLSPSGQECIDTDECVIIPDMCRNGVCQNTQGSFQCTCPPGYLLSSDGLICIDMRRSYCYNDFVGGQCTDARAGNATRKE
CCCSLGAGWSSPCNLCPRPSDASFTELCPDGPGYAPSLTPDLYEDINECKVFPGICENGICINTDGSYRCQCQPGFILDT
TGRICVDRNECQENYNVCGFNSTCYNTLGSFECNCGEGYQVGRRGTCEDINECRRRRGQCAFRCQNLPGSFRCLCPNGYT
LTDDGRHCRDLDECDTNLNTCRYRCKNLIGKFMCQCDEGYTPIGGDGNNCRDINECITNHGVCQNGRCRNTEGGHTCICN
QGFTLGPSGKDCIDRRTGFCYAYVPPSGCESSQGGMQPVTMESCCCSGGRAWGSTCQICPVYGTIEYNRLCTATTPVDPC
QIVQGLCENGHCLGGSGGYLCQCNPGYILSPDGTRCEDENECNRVPPPCSYQCKNTPGSFRCGCPQGYLLSEDGLTCREK
DECSMGIHECQFECRNTLGGFRCVCPEGYIQHGSTCIDVNECIQTPDICGAYGTCQNTQGGHRCECQRNFRPDPSTNTCV
DINECEDQPDICQYGCQNTIGGYRCVCPDGFEENFYGRCIDNNECRQSGKCGQATCYNTQGSYQCGCNNGYAFDQQNLAC
NDVNECQGSYGNTNSPCQYSCDNTDGSFSCGCPPGYTSVVQGACVTDRDSVQPCYSCNRQPRQRRSATETNDKESTMISN
NTAILYHIPLSKAVPKQQIAKFKTGYTRVVARYEYVILSGNEDNIFMMKKKSDGMSLLRFSKHVKATGLYELEIEGVLKR
KNDTILAEVQTVVEEPVAMQIQVQIVADEEE
>NP_001028820.1 matrix metalloproteinase 16 precursor [Strongylocentrotus purpuratus | PB0112
MNSKMMTGYVGIALVVVFTCAVVDGQGYGGGVADSQRDLEDALSYMSKYQGLPMSNDPNTRMALVSHTDLASTIRNMQRY
MDVPLTGHIDGATKAKLTQPRCGVPDPSGQDTAGHALGGRMRRFAHTGGKWETHSLTFRILNSANRLRGSESDDAIRRAF
KVWEEVTPLKFTEVQGNGRADIYLTFGSGDHGDQFPFDGPGFTLAHAFPPQSGWGEMDGDVHFDDAETYTVSSYDGTNLF
QVAAHEIGHSLGLGHSTDSRALMAPFYAGYIPDFQLPYDDQQGIQRLYGSKRPSVGTTTKKPPQPGPNPKPEPGPNPGPT
THAPDTRCKKTYDAITLIRGELFAFQSDIYWRLRFPMELISRDNGELTSHFWQSFPNKIDAAYERYFDHMIFFFKGNEYY
KYNGLELVAGFPKPIKTLDPRLPANLDAVISFSEFSKTYFIKGRKVWRFDELEQRVDEGYPTNIKRVFPGVPSPVSSAFV
HIDGTAYFLKGYEYYRYNETLKSVEDGYPRRFGVDFLGCDPNKLVQLGLNSTGGTGNSNINRPTKLFILLLTISAVLNSV
LQ
>NP_999631.1 3 alpha procollagen precursor [Strongylocentrotus purpuratus | PB0113
MKYREVLERHVFVCLSLLIIVFAYWADAAACVGCLSATCICNGTKGERGDRGYVGFPGPPGPGGFPGVEGPPGYKGQKGN
LGIAGSGGPKGFRGSLGNPGIPGIPGIPGEPGQEGPPGEPGIPGCNGTKGERGPSGPTGFGQPGSPGPRGDPGPQGPPGD
TTYGLKGIKGEPGRLGRDGYPGTPGDSGPTGPKGISGDPGLLGSKGTRGLKGEPGQPGVQYQGGKGEKGSVGTQGLPGES
CRDQAATGNDTTIVQGRPGPKGDQGEYGDKGDKGFLGMKGMKGPKGQYGLKGEKGLSGPQGPRGKIGKDGTPGNQGMKGS
PGIPGNPGPTGFNGQLGDKGDRGPKGRVGPPGPPGPSVPVNDKGTKGLPGPSGRHGSAGPRGYPGEKGRTGYDGKAGQPG
PPGSAGDRGVPGPVGIGEKGEPGNPGIPGMPGPNGFQGLPGRDGPKGDKGMAGLTIQGLPGMDGRPGPDGPAGLPGQVGD
AGPQGLIGEPGNGLPGDPGPKGQTGRDGPRGIPGDVGSSGQPGLPGPQGSKGEACAACRSGEIGPKGDPGQSGEIGQPGQ
PVYNGNSGPSGPKGDRGLRGLTGRDGQDGPQGPPGSTGRPGNKGQLGLQGEVGFTEPGPRGIQGDPGLKGDNGLNGEPGP
PCEPGAVKVNGEKGALGPPGPPGRDGVPGYQGQKGDRGLPGDSLRGSNGEKGDQGPRGERGTYGSPGDKGEVVYYETGTQ
GPKGEPGNPGTAGPPGPAGPTGNQGLPGDQGPDGYQGEKGSQGQSGPPGNSIPGSPGEKGAQGIPGDVGQPGQPGPTGPL
GNPGIPGAFGEKGDFGPQGNPGGQGLRGLTGQPGQPGIGGERGNIGDPGTRGRDGIPGQAGGKGETGPGGLPGGPGIKGE
PGLSIPGQDGSSGTPGRDGAPGGPGEPGPSGPRGEPAQPLLEETRITRLNGQRRPPGQPGDNGAPGNDGEPGPAGQIGVK
GSPGPLGPGGSQGPPGSPGPIGAPGEKGERGGMGTPGSPGPSGSPGAKGEPGLPGPLGEKESRGPGGVPGSKGESGIPGR
SGGIGSPGSIGLPGLNGVKGEPGIPGNSGIPGGRGLNGEPGPAGFKGFQGLLGVKGDFGIKGQMGFPGPKGDNAQMGIPG
QNGGEGFPGRSGIPGPQGAPGSPGEPGTDGSNGGPGSKGEKGQPGIIRDLLAGWRKGVKGDPGRTGPEGAKGNPGLPGIP
GESGDAGLPGSEGRPGQPGTSGPPGPPGPNGEPGLIGRTGTPGDPGPRGERGSYGTPGEDGIPGVKGDSGDPGLMGLPGG
PGLPGPGGPPGESGFPGVRGVKGIPGTPGLSALGIKGEPGFPGLKGDSGQPGLNGGSGSIGLPGMKGTKGETGPVGPRSP
LPPVIPGPKGEIGIPGANGDRGDKGDRGEPGRPGFQGRPGESGSPGLNGQMGDPGGPGFQGLKGSKGEPGPIPNVFEMKG
VKGDRGGPGPDGPQGPPGRDGRPGPQGPPGLTGDKGTPGVQGNPGVSGVPGEPGLKGEQGFRGQNGQPGDPGFPGTKGEA
GIPGSSSGFFITRHSQTTSIPQCPQGTAKMWHGYSLLFVQGNERGHGQDLGKPGSCLKRFSTMPFLFCNINNVCHVASRN
DYSYWLSTTEPMPMNMAPIRGGQLQPFISRCVVCEAPAQVLTVHSQTVNIPDCPDRWGVLWIGYSFMMHTGPGGEGSGQM
LSSPGSCLEDFRSSPFIECHGDGKCNYYATTYTFWLSSITGNAQFTMPQSETLKAGSLRTRVSRCAVCLRNQ
>XP_030850587.1 uncharacterized protein LOC105444772 isoform X1 [Strongylocentrotus purpuratus | PB0114
MQGWTGPTCDEDVDECAVSHDCSQRCIDNGMGMGYSCACYQGYQLQSDGTMCQDIDECVLVRDCSQECSNTEGSYICSCN
DGYSLDIDMRTCNEIDECLSNPCFNGVCTDLLSSYSCTCSPGWLGFQCNNDIDECSSADMNACSQICTNTAGSYDCSCTA
GYELHHDGTTCNDINECLFTNDCTHICNNTVGAYLCSCRPGYSLHFDGFTCIDIDECSSADMNACSQNCTNTAGSYDCSC
TAGYDLHHDGTTCTDINECLFTDDCTHICNNTIGAYLCSCYPGYSLHVNGFTCIDIDECASSPCYEDRTWTCINLENAYD
CLCNSGWQGINCELDSDECQEGAPCNHTCTNSPGSFVCSCNPGYYLDLDGVSCRDVDECSSNQCLNGAECNNLLNAFSCD
CPPGWEGHTCETDIDECYSGPCLNEGTCIDHLNSFTCNCTEGWFGTYCQSGYCALNPCLNGGTCIPAEQQCACTSLYAGT
TCNIDQTQDGVSTVTTHPRNKTVRISEMVVLNCEFQNVQHFDWWRDGKKVPDTRDISNYVIDEMSPPDQAYYSCVGITEN
GPRTESNQALLRIRDMSIFHLKFKLVENFTSIYADQESSDYKSLVRAIKEKFEAVFEALETESDTTCTIYIHVNQLLPDD
GVLVDMRAYIADCSMTTQEAMDLLWSGLFHVEEVSDGYVDPSLLLVLSTVLCPNTSWSSPYGTVQFLSGDLHSWSESSGE
CPWFTVNDGESLARAVCYGDYISPCAWVPSDNCGGNKTADQLLIYLRENPMTAERNTQDILSVLTVISQDTNISSAVVNA
AFDILHQIGSISQPTQENVALVVDILSILATLDKGLIMEAEIMNGAVSRATEALEEILLAINLPFSQTLQYVASNLVVQV
INSESDGVRDGIVFSIIGDDSQSFDESDVQVSTNNLGKGNLGGAVQAAIVMGPETIDEGTRGNIAFTVYRDDALFVMDGQ
VGSNDGRRNITVNTNIIGASLGTSETTPLNAPVTITLAHKQQTGMNPQCVYWEYSTNAWSSDGCDMTNTSKTHTECQCNH
LTNFAVLMDMSGIPRQSERVEQVFRILSYIGCSFSIVGLLVTLAVYITDRKLRCLQHIRILMCLCITLLLLYVFFIIMTA
LDRYPGESEVSPGLCGVIAAGLHFTTLSSMSWMGVEGINMFLMVIRAMDSDIPLFMMKASIIAWGLPAAIVLLTGAISRQ
NYFNSDYCFLQKWPLVGGLLIPLAFILAHNVIIFALVMRRLVRINSDGGKASELKSEVRLEIMRRLKNGMGFLLLLSLTW
LVGYFTVIEQLNLAVHVIFILLNSLQGFFIFVFYVLRQPKSRAHLQEHLGCCFQDLPLTTDAGLMSMKQTTVTGTENPYN
DSVLSKSDNDDNVSEKCE
>XP_030845894.1 vascular endothelial growth factor receptor 1 isoform X2 [Strongylocentrotus purpuratus | PB0115
MTLKYDRPFGRHRHYHDHGDTVWNTRINNAVIYGPNIDKVNCCIQGHRTRTSRQMRKKRYKQNTGIYSCGHCIRTTSDRG
TSEVRGRSGGPLRWSDGGSGGRSFVTPMTRPASLGSSDVAMMNLLWSLLLLATFAFMPVTCQNILVTVHPDTVQVTEGLS
ATLHCNYTVPIIDSSLDQLDQDLEPVQVSNQDPTITWLKDGAVLRTYSGVGRNTVTQSDRIAIVAPTSLMISRAVDEDAG
TYTCQIEQGALIGSASATLNVVGSTPDLLGHEGSYETSILEGETLRLQCKGSYPLSWTYYQGIDHSKVFIRSTLTPILDS
SSWNETSELLVVNATTTDTGYFTCTHTHDSEDFSRDIYVYVNASDANRLFLPSDTTTISVYALDPFILPCRVTVPSTEVN
LVLPNGGVVSRDELPSYDNKIGFSVSGVEADLYQGDVSCRATYEGSTVEQTYFVQIIRKPTILNSTADIKIKEFTKLTLV
CEGAQPLIWVHELPDLEVNIIVSTLRRPNGDVYYRSILDIDPAQYSNTGYFSCLFLRYIKSEDLSLRTSVYVFVSSDDET
RIFLPKYATEHIEYNKSNPVTVPCRISDPSRLVTFKVFYKDTYKEYLTFYWTYTYDPKVGYLLEPERIDVEAISLIFTCY
AITANRTSNQTLPDNDRNLASMTMILDAGANEKPLLKLQVTQDKQEVIAYKEGFQLNCIGTVAAYLLSLENSVEYQPSFA
WVRPGGQRPTELERKYDEFGFDTTTYDAQFIKFMIVENATLEEDGTYTCYAENIGLALEEEITVQVHARGYAGISHRYNA
TDPSTNLTAIVNHPKCISFDVPAYPPPQVKLSPQRNWVLTMDSSTKILSMCSPNVSEAHEGDYTVYVWNEYENASISFFF
SVQVPPQSFISMDPAPIRLFNSTINGFVKDEMYTLECKSTGKPKPMARWFYKRCSANPSVELECGSSESLDLVTGTASGF
ESVEYSHDGSIATLTVEASVWTMYHCEVWSTSPFFNDVQEIVEFKVLDSAAGVSISTGSDIAYISDDLTLECHATVFFFT
EIKWVFINPNGTDVWLNSSAPKYSPPLYSLVSTLLVTNVSFSDAGSYVCVAANGSNPILEKNASQVISVREVSKPEILQA
SEEPRVISLDRMKENLRIQCLAQGYPRPSLSLYRIQAGSIPLNDAVVGGNASVVWLDYEVANPPLDKSGRYECVAESRGG
EDRQTYDVSITELPKLKIEIGDSEVKAGENVTIRCFLVRGHPIPKVQLKKENVQVYLWQGVGNISYTLTADINAGGNYYC
EALDANSTSEYAELVIEQPPPGILERILPYLVSIICVIFLIILIYCMYKYRRRPKVRRASRLPPIEMPRFGSNRRSIYSV
SDDPYENIAYNQRWEFPRERLKLGGVIGKGAFGMVIKAVAVGIDGTENNITVAVKKLKSGATSLEKKALWAELKMLGHIG
KHLNVVNFLGACTQNGPVLAIVEFCCHGNLLDFLRSKRKYFSETPEGTGSQSHTGHSSSTGASNTFQTSSGSERRMKAVY
DQIIPEEVFSPLQDDPINSQDLLCYSFQVARGMEFLASKNVIHRDLAARNVLVTENYTLKICDFGLAKHLYDDPDYVASG
KQGRLPIKWMAPESIFDKVFTTYSDVWAYAVFLWEVFSLGGSPYPGIQIDEKFYNKIKNGYRMNAPDYAPPGVYDTMLEC
WTPEPEARPSFSILAVRLGDMLEANVASDYIELNMPFEQANNEILQELPSPHEHTPLLQPHPPTHFKPSPANSTPNTPPV
TTHMVPSDSGVSAQDRDPSLPSNGMGSQPFLSKDAVQNNTTVQEINELEEEMNSHEDDVFLAPEATTNGLTGFRVNAQNT
WL
>XP_781575.3 matrix metalloproteinase-2 isoform X1 [Strongylocentrotus purpuratus | PB0116
MVDISSSVSSTFTCMRATMTFISVAVVIIFHLAVNSDALPMRDAQDAKMYLMNYGYLKQSDMANGQLTTEGDVVKALKQF
QYMANIDETGTLDNDTMRMMKMPRCGMPDMVGTGSHDVRKKRFTLSQLKWPYTDLTYRLDGTTPDLPAALVNQIMALALK
AWSDVSSLTFAQVAADQPADILIDFFEADHGDGNPFDGPGAVLAHAYFPNPNPIAGDAHFDDAETYTDGIPQGINLFQVA
AHEFGHSLGLGHSTIDAALMAPFYQGYVPDFELHPDDVAGIQAHYGQNTNQAGGGDDGDAAPPTPPASGDCISQFTATTQ
TADGGFYFINDTHAFRIGPNGLEAGYPKTIATEFPGLPNNIDAGLFFQDNGKTYFFKGGDYYQFSSQTMDDGYPQAIATA
FPGLPDDLDSAFVWTGNGRVYFTKGDQYYRFSAGVGVDDGYPRPLSLWTNLPPTLDAAMQHANGFTYFFSGDFYYRFNDD
EFKVDAGYPRDTSVGWLGCAAAIGSGNVTVSPPGGGSTALTSAGLPSLLLVILIICSLYLADLCVLVNL

>XP_030853763.1 laminin subunit gamma-1 isoform X1 [Strongylocentrotus purpuratus | PB0117
MKFLLVLGMVALCRANQNSIPCYDDLSRPQRCVPEFENAAFNLSVEATNTCGEYRDTRYCRQTGVQGGARGRGQCYNCQS
GSHPARYLTDFHSEERMTRWQSETMYEDIQYPNSVNLTIHLGKSFEITYIRLKFYSPRPESFAIYKRTCQDCPWIPYQYY
SGSCRGTYNLPDSEYVSYDDETLALCTSEFSDISPLTGGNIAFSTLENRPSARSFDNSAVLQDWVTATDILVMLTRLNTF
GDEVFRVPNVLRSYFFAITDFSIGGRCKCNGHASHCVEAPNDPYNRLVCQCEHNTAGPDCGECLPLYNDRKWTRATAGNA
NECMRCNCNFHADRCFFDEELYNRTGSGGHCMECRDETSGVSCERCRDNYFRTSPDARCQPCNCDQTGSLNQQCDSSGRC
QCKVGVGGDKCNQCLPNFYDFGEGGCRSCECVRAGSVDNNPDCNQGTGLCNCKLHVEGRDCETCKPGFFNLQEADEFGCL
PCFCHGHSSSCSSAPGYDIAYIESNFNSGVDGWKAESRNGDQELLVYNAIRQDIGIATVDNQPMYFIAPDEYLGSKLFSY
GQELSFKLRLGSDDVSLSVEDLVLEGGGRQISAPLVAQGNPRPGVYPQKFTFKLRAEDDMGWVQRPSAFEFQSLLSNLTA
IKIRATYSDRGQGLLDDVRLVSGRRSVGPQSTRATFVELCSCPTGYVGQFCESCAAGYRRDPYGNGPFTRCIPCECNGHA
DYCDVDTGECICNHNTMGTSCELCQDGFYGNALEGTAYDCTRCPCPGGTNCFVDNLGDVVCTECPSGYVGNRCDYCADGY
YGDPTGIQGQRTACGQCYCNYNIDPNSVGNCDRFTGECLKCVFDTGGFYCENCLPGFYGNALGSPKGEQCQACNCYVSGS
TSNECDQSNGQCSCMPFVTGRDCSECEAGYWNIDSGRGCEPCYCESTGSTSDQCDIRSGQCPCKPGVDGLRCDQCQYDHY
DYSVEGCTPCECNPQGSLYANCTDDGVCDCQPGVIGDKCDSCEENFYNIALGCIPCPECYNLVRDNVNVHRDNLDALRDK
INQISSNPTVINDTDFEMRLRELEGLLNQTIDDAQRVTAEDRTLADNLNAIKDDLGDLRLALARIRAKIDQADGVTEAAK
QDVAEAMAIINRLKRMLPSAQEYLDNEGWALLEKLRGLTANMSAQDRLMQEIAREAKQLADNHTEMALMVEETSARALEI
AYLALDAARDSGDGGDLEAMVEGVERKYVDAQELFNQASQAADECFERAQRAAEEALRLLTKANMPLSPIDVNSLLDAAN
DISFRARQLMDEANALRRENADLLAQVAEDARTAADLLDQAVAAENLIDLLLAKADNARSIALEAKRKGDETLQEAKDIL
RVLQGFNEEIEESKQAADDAKLRIPDIEAMINQANITAHNASDAIAAAEGDAMKARDYARMAEGNATLASEAARGVRTDA
EATMLEAQEQNDRADDLAADAMETMMRLNAIEGQAEDDGDMADRAQEKANAAKQVTGAALQAAEEALAQLQMIKGELDSA
GSIDLERLQDLEDELLNVNATITYDLRLDDTMDELRAYAMQQAGWISAYQFDLSEIRAEVANVEEIRDALPEFCPNESIL
EP
>NP_999700.1 complement factor B [Strongylocentrotus purpuratus | PB0118
MERLPILPSPLVCFRLPESPANGYVRMRGKSARSIAVYRCNPGFELHGQRTVVCNEATGSWQGDVPRCFRPPSCPDPNEP
SGMLALVLDENSGIKHGDLYTERTVFNYTCQTGYHPTGDVTITCQNGSWEADADVPECNKIICAPPTLEPIENGTHNIEN
RTYNVGEMVQYECNEGYLVDGISWQVCQSHDGPNGIWSDNVPRCKVARCPHPGSRHLDNGEISFSPRNGQGATNSWPVGA
VMTLRCRSHLELLGSSERVCQPDGHWNGTLTSCHNEEYDCPALGNTIHGSKVGSPQYRVNTKVNFRCNHGYQMVGSEERM
CTFSEEWTGEMPRCMGRDEFDELSRVMNGLGKTFDEIVIDGGSWVGRNDTSSNSGLRRKRTIKLSDGMDIYFAFDASNSV
GLKNFEIGKTFAKQLVGKLQVNTSPGGTRVGAVSYSSEARRLFNVNDFTSTVDVVKAIEANVNYTNKGTNLPAALETIGV
MITETADESGYSSRKRILFIITDGFSNVGGAPSKSAQPLKEDAALKIHCIGISRNTDKTALAEIASPPVSEHVFYLSDYN
ELERAVEAITSTNRSYEECGESKHPSATSRIVGGSESHSGDWPWQAALYDEDSNQLLCGGSLIEKNWILTAAHCFSGENT
LSQNGTTVYLGLTHRVNDLNRPSVRCEGIDYAPGLLQGLDGGEHNDIALLRLDREAELSPFVRTVCLPPSDPQKVNWYVN
PRRTAFVTGWGHTLKGQTSPALMEIMIPPVLDSSCSIAMSAHGIAVDTTTELCAGIERKDSCQGDSGGPLVVQRNNKYRQ
IGIVSYGIGCGVTYGVYTRVPHYVDWINGIINK
>XP_781087.2 secreted frizzled-related protein 5 isoform X2 [Strongylocentrotus purpuratus | PB0119
MIERVLVVLLAFAASSPGVWGQETETDMAMLGVNSRTYPLDLSGRPKETDCVDIPEDLSLCQNIGYTRMRMPNLLEHDSL
DEVRNQAKSWVPLLLQRCHEGTQLFLCTLFAPVCLEVDRPIYPCRSLCEEVQAGCGPLMESNCFPWPAMLQCDKFPEDND
LCIRLNMRNQNGTVEAQPFEMSAAMQEAYMMHFTQCHDDSLEDTLLRKFCNSDFVLKVKIKTIRESKDGKKYIGDPNPEK
LEVLKQGSLKTKDLQRLTFYVREGANCQCDMLERSGNYLLVMGHRDSKKNRKLFMTFVHSWEKTRDFRRAIKGFENPDMC
ENLETATEGRREEIAPQDAEPHEMTPADEVLLASQTNTPVNDGVYTTHQVMADETPSPKTNTRRERKRGKRTRDRPRKNR
ERENREMPVRRARSKWD
>XP_030847127.1 IgGFc-binding protein [Strongylocentrotus purpuratus | PB0121
MDEQVWIYRDVTSMNLVTDFLWVSYDGMDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPD
QCDGVDPGPTDPCEDGVNSLSASNDLCYYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKG
GKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYI
PSGGAWTDPGCTQHCLCRGGLAECSEFQCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKY
NFQGDCDYTLVRDCQNSSDYHLWSNNERLRPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYR
DVTSMNLVTDFLWVSYDGMDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGP
TDPCEDGVNSLSASNDLCYYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLL
VEECPLNCPSNTVYDPCFSGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDP
GCTQHCLCRGGLAECSEFQCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYT
LVRDCQNSSDYHLWSNNERLRPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVT
DFLWVSYDGMDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVN
SLSASNDLCYYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCP
SNTVYDPCFSGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDPGCTQHCLCR
GGLAECSEFQCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSS
DYHLWSNNERLRPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVTDFLWVSYDG
MDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVNSLSASNDLC
YYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCF
SGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDPGCTQHCLCRGGLAECSEF
QCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDYHLWSNNE
RLHPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVTDFLWVSYDGMDSADVYLS
YFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVNSLSASNDLCYYLKDPSGP
FESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSS
AASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDPGCTQHCLCRGGLAECSEFQCGENEECE
IRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDYHLWSNNERLHPSDSVS
YLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVTDFLWVSYDGMDSADVYLSYFAGRTCGL
CGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVNSLSASNDLCYYLKDPSGPFESCLEIVD
PDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSSAASTLSCNT
TCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGASWTRPDCSQQCTCEGGRAQCESFQCGENESCDIKNGVPSCY
CKDGYTSLGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNELLRPSDKVSYLREVTLEL
KGNIYSLIKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNFDGDK
SNDLLLPSGEVARSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPEDYYQS
CLYDVCETGDDALCANLEEYAQACRNRGGQPGNWRASVPECPLDCPSNTVYDPCFSGCPETCSSAASTLSCNTTCQETCR
CADGLVLDDGKCVDPSQCGCTLENRVYIPSGALWTRPDCSQQCTCEGGRAQCESFQCGENESCDIKNGVPSCYCKDGYTS
LGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNEILRPSDKVSYLREVTLELKGNIYSL
IKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNFDGDKSNDLLLP
SGEVARSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPEDYYQSCLYDVCE
TGDDALCANLEEYAQACRNRGGQPGNWRASVPECRKSAEMSGALWTRPDCSQQCTCEGGRTQCESFQCGENESCDIKNGV
PSCYCKDGYTSLGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNEILRPSDKVSYLREV
TLELKGNIYSLIKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNF
DGDKSNDLLLPSGEVARSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPED
YYQSCLYDVCETGDDALCANLEEYAQACRNRGGQPGNWRASVPECPLNCPSNTVYDPCFSGCPETCSSAASTLSCNTTCQ
ETCRCADGLVLDGGHCVDPSQCGCTLENGVYIPSGALWTRPDCSQQCTCEGGRTQCESFQCGENESCDIKNGVPSCYCKD
GYTSLGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNELLRPSDKVSYLREVTLELKGN
IYSLIKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNFDGDKSND
LLLPSGEVAKSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPEDYYQSCLY
DVCETGDDALCASLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSSAASTFSCNATCQETCRCAD
GLVLDGGHCVDPSQCGCTLVNDVYIPPEGAWTSPDCSQHCQCSRGIAECEPYVCGRNEECQLKNGIPECYCQDGYTLLGG
YCVKAPGYCQVWGDPHYVTFDQRKYNFQGDCDYTLVRDCLNSSGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLSWD
FVVRVNGIDFTNNLPYFGDGIIIFRDFNSLILITNYMWISYDGKRSADIFLSYSYWNQTCGLCGTFDGDKSNDWRLQNGE
LADSPVDFGNSWVVTVDECDDVRPEPTDPCEADLVLLADAEDLCAVLLDVDGPFAPCHDFRDPDPFYDSCKYDICALGDE
FLCDSLTQYAEACRQAGGQPDDWRSETPQCPFDCPADTVYDPCSSGCPETCSTAISSIPCNLTCQETCRCADGLVRDGDQ
CVDPSQCGCTLENDVYIPPEGTWTSPDCSQHCQCSGGVAECQSYVCGRNEECQIKNGIPECYCQDGYTLVGGYCIRAPGY
CQVWGDPHYVTFDQRKYNFQGDCDYTLVRDCQNSNGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLSWDFVVRVNGI
DYTNNLPYFGDGIIIFRDFNSLILITNYMWISYDGKRSADIFLSYSYWNQSCGLCGTFDGDKSNDWRLQNGELAESPVDF
GNSWVVTVDECDDVRPEPTDPCEADLVLLADAEDLCAVLLDVDGPFAPCHDFRDPDPFYDSCKYDICALGDEYLCDSLTQ
YAEACRQAGGQPDDWRSETPQCPFECPANTVYDPCSSGCPETCSTAISSIPCNLTCQETCRCADGLVRDGDQCVDPSQCG
CTLENDVYIPPEGTWTSPDCSQHCQCSGGIADCEPYVCGRNEECQVKNGIPECYCEDGYILLGGYCIRAPGYCQVWGDPH
YVTFDQRKYNFQGDCDYTLVRDCQNSNGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLSWDFVVRVNGIDFTNNLPY
FGDGIIIFRDFNSLKLLTRYMWISYDGRRSADIFLSYSYWNQTCGLCGTFDGEKSNDWRLPSGELAESPVDFGNGYVVTV
DECDDVRPEPTDPCEVDSEVSRKAAELCSILLNKDGPFAPCHDFRDPDPFYDSCKYDICALGDEYLCDSLTQYAEACRQA
GGQPDDWRSETPQCPFDCPANTVYDPCASGCPETCSTAISSIPCNMTCQETCRCADGLVRDGDQCVDPSQCGCTLDNDVY
IPPEGTWTSPDCSQQCQCSGGIAECRSYVCGRNEECQVKNGIPECYCQEGYYLVHGFCVQAPGLCQVWGDPHYMTFDQRK
YNFQGDCDYTLVRDCQNSSGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLIWDFRVRVNSIDVTDNLPFFGENIIIF
RAFNSLKMLTPFMWISYDGRRSADIFLSYSYWNQTCGLCGTFDGDKSNDWQLQSGELASNPKDFGDSWVVNVDECDDVRP
EPPNPCVENSITTEEAESLCNILLNDDGPFAPCHDYLSPDPFYDSCKYDICALGDEYLCDSLTQYAEACRQAGGQPDDWR
SETPQCPFECPDRTVYDPCFDGCPATCSSASSPVPCNVTCQETCRCMEGLVLIGEECVDPSRCGCTLDNGLYLPVGETWK
NPDCSERCSCLGAGELQCESTTCGQNAECNVKNGVPECYCQEGFVLYDGRCIDGPGVCQIWGDPHYLTFDSRKYSFQGDC
DYTMVRDCLNQTDFHLWADNRRRRPSSEVSNLDKLVLDYDGHRYALMKSQRVKVDDVRVSLPFISPSRDIEIWSTGRPGN
VILQTSFGLMVKHNGQRAADIYLERSFWNRTCGLCGTFDGNPDNDWTGADGVVRQRGEKTDFANSWVVNRDECSDIIPEP
EDPCAEGGETLKQAEELCYVLLQPDGPFSPCHDFVDPADYHTACKYDLCARFPDDDYLCDSLNGYASACRQAGGAPEDWR
SETTPCAYECPGASVYDPCASACPTTCSDLSSAFNCTLPCIETCRCPDSMVLDGTECVDPEECGCTLDNNVYLSPGESWT
NDNCSETCTCMAGEIICTENTCHQFANCDIKDGIKKCYCFDGWSGDGYTCTRSQGVCQIWGDPHYLTFDSRKYSFQGDCD
YTMVRDCLNQTDFHLWADNRRRRPSSEVSNLDKLVLDYDGHRYALMKSQRVKVDDVRVSLPFISPSRDIEIWSTGRPGNV
ILQTSFGLMVKHNGQRAADIYLESSFWNRTCGLCGTFDGNPDNDWTGADGVVRQTWAEKTDFANSWVVNRDDCSDIIPEP
EDPCAEGGETLKQAEDLCYILLQPDGPFSPCHDFVDPTDYQTACKYDLCARFPDDDYLCDSLNGYASACRQAGGAPEDWR
SETPQCAYECPGASVYDPCTSACPTTCSDLSSAFNCTLPCIETCRCPDSMVLDGTECVDPEECGCTLDNNVYLSPGESWT
NDNCSETCTCMDGEIICMENTCHQFANCDIKDGIKKCYCIDGWSGDGYTCTRSPGVCQIWGDPHYLTFDSRKYSFQGDCD
YTMVRDCLNQTDFHLWADNRRRRPSSEVSNLDKLVLDYDGHRYALMKSQRVKVDDVRVSLPFISPSRDIEIWSTGRPGNV
ILQTSFGLMVKHNGQRAADIYLESSFWNRTCGLCGTFDGNPDNDWTGADGVVRQRREEKTDFANSWVVNRDECSDIIQEP
EDPCAEGGETLKQAEDLCYILLQPDGPFSPCHDFVDPTDYQTACKYDLCARFPDDDYLCDSLNGYASACRLAGGAPEDWR
SKTPQCAYECPGASVYDPCASACPTTCSDLSSAFNCTLPCIETCRCPDSMVLDGTECVDPEECGCTLDNNVYLSPGESWN
NDNCSETCTCMAGEVICTENTCHQFANCDIKDGIKKCYCFDGWSGDGYNCTRDPGTCTVWGDPHYETFDGRKFHFHGECD
YTLVRDCYNVTSHPSFLISSGNIKRNPEDKVAYINEVRLEIYGKDILLTLGGGVYLDGVSVNIPLNINSGQIYVFTSGKD
TIIRTVVGIKIQWNNRNTATITVPSSYHGALCGLCGNYDANPDNDFRLLNNVVVTKALDFGNGWVLPGVLECGVSIDEPE
PCQENDDFLFAQDACFIVLDPEGPFVPCHPFLDPTPFFEYCSYDACATSPNDTVVCDDTSVYAERCIELGYPPNTWRSAE
FCPIECPEGFISSPCVPACPETCFGTTEGEGCNDETECREGCVCPEGSVLADGECVPREECGCVFTDEELELYLPVGESF
VSVNCSRVCTCEAGANQICESMSCDPNAYCGVEEGERGCICMEGFLGDGLDCIEVTEMPTTPMITTTDLGVQSTTSDRGS
STATPANVSTTIDVRTTEMFFNVTTTASTTTEQGTDTTEFVNATTPVIVTNETTTDATTEEQTTVLGTSPVIVTNETSTD
VTTEEQTTVPGTSPVIVTNETSTDVTTEEQTTVLGTSPVIVTNETSTDVTTEEQTTVPGTSPVIVTNETTTDVTTEEQTT
VPGTSPVIVTNETTTDVTTEEQTTVPGTSPVVVTNETSTDVTTEEQTTVSGTSPKVSTIPMGSSTEAATTTDSLMTSSMA
SGATTAVVMTSEETQPTTKDGATTLGMTTDGPTTQEMTTQAQTTTPPIETSTCRIWGDPHYITFDYRTFHFQGQCNYTLA
KLCNESLTDEDRPWFDVVINNRLKVVDGSTSYLRELYLNISSHKISLLQGPVVLLDDVLQRLPYYSSSGLYITYAGRYVV
VSTSTGLVLRWDGEGGITLTLPPAYSGATCGLCGNFNGEASDDFVLPDGSLAADSTSFANGWSLEDDCSDTTQIDPCSTD
SDLLATAQSRCSILSSDAVSGFAYCQQSVDSAFFYDSCLYDVCAELPGDEGADCNAFAAYHQTCLDEGHPITEEWRTGSS
CDSACSSSNSTYQTCTSSCPETCPGRAVDPPCDTRCVEGCDCDDGYLLDSDSCVPISQCHCERDGVFYSAGTTLLSSTCS
ELCTCMSGLFMCEVASCDENASCGMDENNDPTCVCNIGFEGDGYTCSAIVYDLQVCTIYGDPHYVTFDGQDYTFQGDCVY
TLVTSDCINGTSDNTFSVTATAAKDSDTHSFTYTRELVVNVEGLAITMTTTDIFLDGVRVNVPFYKNNVYFTQSGEYKVV
MTNYDLAVRWDGVSTAEVWLSEYYDGNVCGLCGNLDGDANNDFTKPDGSEASSIEDFGDSWSDGAISCPETPTDTNPCDT
DATLRDNAVTQCSNYLNDTNVFGDCYSTVTLDPYYESCLYDMCATNLNSSVLCNIVEVYATRCQLQTDWKRNVDGPCSYD
CPANSVYSSCVTECPSSCADLGTVDQCTSLDLGCTSGCVCEEGFVYEDDQCTVASLCGCTYNGLYFKSNEEYISDGCGQR
CVCDGLSHMMSCESIQCAFNGVCEIRDGNRACYCQDSTDGATCYNATVGYTITLDQATWSTLTLTWTTDQEVTSVIVQYR
FQGEEVWSNSSTVDATRQIIILDDLTSSQSYQVRLVFVGDSFYTRSSVEVFDTCTPGVQGPECATDYSSTSAYDFNLVYA
TSASLELKWTLPEIAEIQWVHLTFRESSTDPWSNGTLLEGTATSDIIQGLSELSSYQVQVAIGLSSGEQAESAVLTLLTC
AGGTVGLNCEGDVPIDASVDTVSSDFVTVTWTVYVTVSQVAVQHRVATSPQARVLITADGWTEEPPVPADRGLYNIEGLE
PGVTYDYRLKLINDTKEQFGETNQVTLCPEGFQGANCEINYAELGAFDVRLVEAMVTSLNVTWQTTVSIVWSQVQYKRTS
DTSDAWLATNQLQPLETGALLTPLAEDTAYSVRVLVTRMDVSSTISDVVQMKTCVAGFRGLNCEIEIPVVTTTPSPTTMQ
TSPPTEPSTEPSTAGPTTPFTNAPTTVAAPLYIIETVGKTSTSLKISWTLQQPNVVQVFVEYKPNLSQTWTQVSASSPEQ
VSFTINGLTPAIMYDIRLMLVYEDSPEAFGEVYTLETCEEGFRGVDCQTAEVSPYRITLSHINSLSITAEWTSPTSVTDV
VLQYRTDSGPWNNGSVVTRARGFYILTGLDDNVAYTLRGAFAEEQSVEFSDVISAVTCEQGFAGESMCDTDYSNVGAYDV
VLSTATSTSLVISWAVSLQADWHMVQYRIDSNSIAPEWFNSTELDANTTSYTIDDLEPNETYRIRVLTRRTTTAGRKKRA
DIAENVGISAEVLVVTCQNGLQGLNCEEFAVVPTTGQPTEPPTQPPRTTLAPSSIPWRDILIGLLVVFGILLIILIFIII
LIYGKVKRRRSQMAKIQEVNDGTQRGYRQSDVLFATDSNSYSSSEVGDHHNGLDYGRDAAADPGHVRISMVGQRDNVRDA
GTSTRWMNDQGYNDGTYRYNAAYDPTED
>XP_030832708.1 cartilage oligomeric matrix protein isoform X2 [Strongylocentrotus purpuratus | PB0122
MQFGTCSIAFLLMLSVTSSQIPVSMGVEADLFDGFGIYNSRIPGVSPAPQENSNIYGDAFFFNGISIRYPIIANQEFFKK
FAKEMRKNEDVYFVIRSRLAPRHHGVLFGVYSSNYYSQDTFRTPLRFELSYNGTNGGKLVLKYRVGDQQRQAEFPNLLVV
DGDWHTIILQFHTERSSTTLTLYVDCRLANQMKIGDKLSRVFSRTVIDGSEMRLGQAGYGMTANPLKGTIQNVRFMYGGP
IGDVLHSLSCSLSTEPKPLDADGWPGATILMDAFQSLSSTLMVLKNGMDDQTREIRHLRNTLENCRMCGPQTIITHGCSS
NPCFPDVMCFDEPDGLGYRCGPCPAGYRGNGSYCYDINECIEAYPCSDVVECINLVPGFRCPPCPEGFIGLGLEGIGLEA
AVRNRQVCDDINECERNNGDCVPNSYCINTRGSHICGDCKHGFEGNQTVGCKQKNTCPNGERSPCHPKAKCIIHRNNAYT
CECIIGWAGDGYDCALDTDLDGYPDYALPCTDKHCRADNCVYIPNSGQENQDGDEMGDICDPDADNDGVPNGPDNCPLVA
NPDQVNSQDDDPVGERCDNCPMTPNPKQIDTDADGKGDECDDDKDNDGILNIYDNCELVPNRMQDDTDGDGLGDACDNCP
MQYNPDQNNTDSDLLGDICDNNEDSDDDGIQDNLDNCPKIPNNPQLDSDGDGRGDACDDDDDSDGVYDIVDNCRIIHNPD
QADYNQDGIGDMCDSDFDRDGVDDQYDACPENPNIFTTDLRTYQTVVLDPEGEAQVDPKWIVFDEGRQIMQTINSDPGLA
ISYQAFDGVDFEGTFFVNTRTDDDFAGFVFGYQDSASFYVLMWKQGPQTYWEASPFRAVGEPGFQLKVIKSDTGPGEMMR
NALWHTGDTPGQSRLLWKDPNNHGWKDHVAYRWRVVHRPSIGLIRVKLYEADSLVADSGFLRDTTMRGGRIGLFCFSQED
IIWARITYKCNDDIPEGVTF
>XP_030838005.1 laminin subunit alpha isoform X2 [Strongylocentrotus purpuratus | PB0123
MKMALGLIVKLLFAAICCVSATSHENETLVLNPPYFNIARGREIEATATCGEGFATPGEQGELYCKLTGNTADIYRPGEH
VIIQGQYCDNCDPGDPAKAHSIEYAIDGTEKWWQSPPLSRGMSFNEVNVTVNLGQLYQVAYVLIKFANSPRPGMFVLERS
RDYGETYEPWQYFAETPSDCQLEFGMQSLEEIRNDDDVICTAGYSAIVPLEDGEIVVSLVNNRPGAPHSSTLQEWIKATH
IRIRLLRTNTLLGHLMAVARQDSTITRRYYYSIKDITIGGRCACNGHAAYCDLPSSNDGRNKQVCRCEHNTCGVECESCC
PGYVQKAWRTSSYSSPFECERCNCHSHSNECVYDEEVALSRGSMDINGNMEGGGVCQNCQHNTVGVNCHLCKPGFYRPEG
RKQSDYDVCQPCMCDPILSTGNCAPLTGQCECKPEYAGPDCTECNEGYYGYPYCRPCDCNLNGTENKVCQVNGGQCPCKP
NYTGRNCNLCALSYYGFPECQRCDCNTIGSFDIVCDSENGQCSCREVYDGRSCDSCRDGHYNFPTCSDCSCSQVGTEEEV
CNKTNGECLCGENFGGQRCERCSIGFYNYPDCLPCGCDDTGSFNGQCDDSGQCPCESNFAGLKCDQCAAGFYKYPACEPC
NCDRYGSFNVLCDQVSGQCSCRPNFQGRMCQQCGESFYNYPNCEECNCDPAGVIDVPGQPLGGCGSSTGGACLCKDNVMG
RTCDTCKPLYWNLGISNPYGCEECNCNLAGTVGGMAICDIAHAPWHKRTGQCFCKGQVTGRTCAECRDGTYQLEASNPIG
CQDCNCDVGGSVHAACDTRTGQCVCRPRVTGVTCDMPEANHFVPDLHQMKFEAEDGYTPNGRRVRFGYDSFEFPGFSYLG
YAIMSAIQPTIRIPITVESPSIYRIIMRYYYPNAGGPTRGRMTVTPADPSQVQASEQSSGIIFISTTIPQFVTVEGSGVI
KPFVLNPGSWVVTIEAPEGILIDYIVLLPSDFYEATILQEHTTEPCIVGTPQQRCNFYVFPEVDQFFVAPGVDGYSVDSN
GGRYPVQRFGDDLIMQELGVDSMALVDDNQNIYGIDLPIFQAGRYVLIFEYYGGGPGQQSALIDVYGSQDTQQGELIFND
CAFLCRAIVLDDDSRVQVFDIQDVMPYAQLTKIGGPYMLSISRVIAIPVESFTYDFVTPTLECVRTADGECLPSTYPVPP
NTILLEGEMNLDAPLPPNIYNPSPTVTYLSNDNQNTASYHDDLVPNSGEVVFVIHYYQPNGESYDTDFRVVGQFDGEGTF
NAKYCPHVSGCRVVVTKPDGSNVFELSDLSQGIQVTLPEGDNRQLWIDDIMVIPVEMYTPDVVNANPQDRAGEFIQYCSA
NDFYFSPDSSGFCREAVFSLSSAFNYGASECDCDSQGSLSFNCDELGGQCNCRQNIVGRRCNKCAVGYYDFPYCRACTCE
SGVCNEVSGECICPENVAGTNCDTCAPQTYGYHPIVGCVDCECDIRGVDNNDLNCDFFTGECNCKPNIGGRQCERCERGN
YGYPYCEPCNCDVNGTTEEICDQTTAQCLCKDNVYGDQCNQCEPGTFYLADSNPEGCISCFCFGVSTDCRSYTRRRARID
MVDGWTTVNFDPSAVRYGSNFANIYVSGTGDTPQNAIYWNAAEKFIGNKLTSYGGKLEYTVRNNPQPAELGGAGPAQPMR
RPDILISGNNISIMYLHIDQPDPGQDLSVSVELKENNFQYSISAAEVSRSDFMTVLANIDSLQIRAQYFDRILTADLLGV
SMDVTRRDGDGAVAQEVERCRCPPQYQGLSCELCAEGHYRLPGSGPYLGQCVPCNCNGHASRCDSKTGQCLECDHNTVGD
QCESCKEGYYGDAPSGDPDACKICSCPQPIENQNFAVTCTFSPQGDQFCICQPGHTGQYCDQCVQGYYGNPLQGQACRRC
DCSGNTDPTTGLAECDQSSGNCTNCVVQTKGRSCEDCNDWYYGDARVQSCQACSCDRCGSDSCDNFNGVCNCRPNVVGYD
CERCQVGYWNFDSCSGCLPCDCSLGAVDSQCDMETGQCTCMPGVGGDKCDACLHGYWNYGPNGCYECNCDPKLRCDPYTG
ECLCPPGAMGENCDQCEDRYILTEQGCQPCDECVHLLLDIVEEMAEDLDEADRNLTDITVGVVAFQRLNNLNRSIHDLIP
EVEDLDNNNALVRGSLGNLTYQIDDLKYQAGQVEERAMAAVTNGNGTANDADILKKRAQQIEADANATIDFIHDVVEELQ
AIGNGTISSNTNLGELLARAQMILQELKDRDLNPGKGAAEEEKRLAQELLDRARALQNDSAEVGDRADEVGDDVDVFLDK
LNELMALCENSDNTTDQVNAILDKHRNPAFEDVLAEVNAKNEMAQEEVTNATNLLDDAYGFLADARRAIDATGVNGSKLE
AAIDQLEPFIERYEEEGRNLPELVDNATDYANDLWNTAEELDRMFDSTRNLSENALKAVRAYQDIGNAIDEAERAARAAL
NASGLALDAANDFGTQPQDSKRRSKKLLRKAVEAGEDMEGSLPKASLLNQSLSLRDQLNDVEQEVEMVKDNLDAVEDGLA
EIERGIAAIPSPSSECTIITNCDATDPTCRLGYSGDNCNIANLGNLAEGAANTAMAAESIGNDAKDRADDMIDRAGDVKA
KLNGLGATIQAANDKMASSQNSIDEIRDIEGKIPGLRDRLRMQHRLMDNMTLSMTYDLAEIQKKIAEARSLANGIKVAAK
FGPDSYVELKAPAEVSESTPISSFSFYFTTQANDGLLYYVGGPAAGDDYLALTLENRNLVFRYNLGDDDAMATVAQDVTD
GLWRYVLVERYGRYAKVTVTTESTGDQDGESSTTGVFNLLDLQPESIMYIGGAPQSADLPGVISNRDFIGGVDEFQFGET
PIGVWNFVNASSVNEGIMRNVTDLAVTTDPDDPNSAVMFDGSGYAIVQRGTKEMSVGNRIQLQLKTLSPNGLLLFAGNEG
NTFFIEMRGGRIYYEYDLGSGPVSKISKNIYNNNKWTTITIFRVGKATQLFTITQGPISEDFAQFSSPGAETELETNNLI
YIGGLVGVPDDQFTRVTRESFRGCMANLVISSQNVDLTAADVQTAGFFPACIRQDIRVATYPGPSGGYTELAMLDDLDLM
DDGDFILRFRTEQPNGLMLYTADDTQDSSLAIMMKDGAVLVVAHRVETAELLTPEDTYNDGMWHTINVRRPARRANARLS
LSVDDNEAVVEAFASRNMKTGGMLFVGGVPEGYDLGPITVPAAASEPFIGCLADISSKHRKITFANRMRDFNAFYGFCDL
SLSSNATEGEVTLTSPAPTSAAGPSTTPSMRNDGPCVLSSNPEDAPEDPTNEGAVQFGVLSDSRVEFPPLKSSEYSNGYD
LSVAVRTGARNGIIYYAADGSQIDLLALFLYEGRPVMVFNLGSGNLRLEPLDGRTINDAQWHTIRTFRDKTSGELYIDGE
LVNSGMSTPGARLLKTTTNFFWGGLSKDLTVANNDVNEASQIGLLGCMKDLTNNGVEFGVRANEYEIQACSQIIEPGVYF
GPGKGYVIPDETFMVNQRLEVRMSIKPRVKSGVIFSVAKPGMDFASFELIDGQLFFRVENGAGKFEATYMPPEGSAFLCD
GNWHDLLVNKEGSVIRITVDGDEGDQVTGPSGATAANTNDPLYFGGIPDGEEGNHPGIERNAHYVGCMRDIMVNDDLINM
ADGIFEGDVDTRSCAAN
>XP_030830576.1 uncharacterized protein LOC100887833 [Strongylocentrotus purpuratus | PB0124
MHFLDAWFPAGVLIIVCCLLSRSVAQLIDPEIRNITASAGDDVLLDCVPPDGEALLISWNKDNDVVQITDAYRDGRIFLD
QKEGMVILNSELWDRGMYSCLILTQDSQIITHRFWLDIAPPTDSDVDSNSAFQCGYCRVRGKVVGGKVSNEGQSPWTALL
WNTNEGKPLCGGVLLNRRWVVTASHCFSLSGLSIDEFEIRLGEHDIEAISDNERTFRAEQIIKHPNFNEQTYDSDIALIK
LQQPVTYTDYIIPLCLPSELRADELLKAETRGFVTGWGNTEEAGDYSRYLRRVRLTIASMQDCGRSHIDIITNNMFCADG
GRKADERDACQGDSGGPFVTKDNNRWYLLGIVSWGVGCARPGYPGVYTRVHRFRQWIMDLVQQDMQTCEESSFELGEELR
ASVKESNNLRLLNQEQQHLIEYFQEELNRKDEEIFDLHERIETFDCPDGLPTSTSPPESTTPTMTNYPVITETRPVTTRA
PIQEDALPCRHNMCWHVSNLARCHGGYCVCDSPDYSRVSCLPIVGSCRIYRNNSYALATATFRDDTRIADTFACEGNPES
NVHIISVYEGPVHTRPASPGDVHVRVTGGDQGPITIVFSSYEPVRWLVSVDEGIMINKFVLTGYYLDLSSVEVVSLLHTN
VTVVTVSRVPFGYGTDGDGVLHTAEFLKYVQNTYGDVGSFSGTYRADRWVLTVPGEAPIVDWMRLPLPIIPMARVESTLS
RTGWTPFPFRYDGSFCACHGDQYVKLLGGSENELDYGVRYVGVVLCQTPSHYKIFLANDLEETFLNVGDGSGGGSDHCEF
VGGHHENETLAQTSRDWLLMPAVSGYYRSVWGEPVSFGSIGGGYRTWTGKIIVSWYDCGITIP
>XP_030845533.1 nucleobindin-2 isoform X3 [Strongylocentrotus purpuratus | PB0125
MGMLEWKLPLLLLLIVHVAQQAPVDPKPAEEDRDRDEGEGIAGEEILNIAEGDGIADLGLEYEGYLREVIQVLEADPEMK
SHMDEMDTNDLLTGKFGKQLNNVGSHIRGQLDELKKKEIQRLRIIARKAMEQQAHDDVSQTHLMDMIAHIDFGNEHTFEE
QDLNNLLQKATKDLEENDRERRKEFKRYEMEKELKRRSEMRRMNEEERAEAMENYEKERKEMKQHAKLNHPGSKKQLEEV
WENTDHLDRKDFNPKTFFYLHDSNSDGFLDEFELEALFIKEVEKVYKDQKTADVQEKFEELSRMREHVVNQIDNNKDKMV
SLAEFMEAASASDFEEDSEWQDLNQESQFTEGDLEKYQEELRRTLEETKAKMAEAGDNFVRVRQPQGQQDAVNMNQAQAQ
QIKDGLSAGLPALKEGNDKIRFEGDTQPVTRHDPPGNIAAANQQPPQPPAGQPQQPPAGQPQQPPAGQPQQPPASQPPPP
PASDQQQQQQQQQQQQQNQPPPPKQPAQQP
>XP_030828530.1 laminin subunit beta-1 [Strongylocentrotus purpuratus | PB0128
MIMAEDLTALYIVLFLSAVASYGQLILAGSGACEGDSCYAGDLLIGREDKLFASSTCGLNGREPFYIVSHLENRNREIFH
CDSRTPWQEGVNDLNHEIKHVVTSMDNSQKKVRWWQSENGLEQVYIQFDLEAVFHFTHLIMTFKSFRPKAMVIERSSDFG
HTWKPYRYFAYDCAGSFPEVSRAPIRNISQVICESRYSAVEPSTGGEVIFRVLPPNIPIEDPYSREVQDMIKVTNIRINI
TELHFLGDHLFDDGDEVFNKYYYALYEMVVRGSCHCFNHASRCVPADGMEFKQQMVNGQCECIHNTEGKNCERCEPFFND
QPWRPAGLRGENNECKRCNCNDHATSCHFDEAVYRLTNGASGGVCDNCLHNTVGRNCEQCKPFFFMHPDRDIRDPNICVP
CNCDPAGSENGGECASHTQGEMVAGMCLCKRYVTGQRCDTCQDGYWELNEANPEGCRECACDLLGSENNMGCDKSTGNCR
CKRYVTGQNCDRCYEGYYGLSADLYGCKQCECDPGGSYNNSCNQASGQCPCRRNIGERQCGQVNSGYFYVNMDYYTYEAE
YARAVGDLSLVDYYPRMRESEYIGWTGPGFMRVHEGGGIEFTVSNLPMSGNYDLILRYEPLLPGVWEDVRITINRPGDIP
TQSVCGNTIPQDDLLVTTLPSGSRHVVLSNPVCLETGKTYTIRVDFTRYSSDNQDSNAQILLDSLVVMPRATIYPIFQGP
DPIEQYRREQWDYYRCGEAHMSAVHSPLSDICKELMFSMSALAFDGALPCQCDPTGSLSNMCDETGGQCQCKPNVIGRTC
NQCAPGTYGFGPEGCTPCDCDGTGSLNEFCNQLTGQCPCRPNTYGQQCNECQPGFWNFPNCQRCNCNGHADICDPRTGEC
IDCQSNTAGFECESCKRGYYGDPTRGSALPCQACLCPGGAGSGNQFAESCQLDQATQTVQCDCFSGYTGIRCDQCDNNYF
GNPTEARGVCNLCSCNGNTLSSTPGNCDARSGKCLQCLYNTDGFNCEQCAPGFYGDAIQRTCRDCQCNVLGTDRSQCDLD
NNCGVCDPVSGQCPCLPNVLGQQCDRCAQDHWKLASGTGCEACNCCPYGAVSSRCDEFTGQCACRSGFGGRECCDCEANF
WGDPRDGCYECDCDEQGSATSQCERATGQCVCLPGVTGYRCDQCARGTTGELPRCEPCGECFDDWDLTILHLRNETYDLI
ARARNIKVSGVSGVYDREFSRLEGLVDYAESLIRGAPSVTETDVDNIQSELDDIRATLEEYRQQVQGLEDMQRRTRGNIA
RANRELDLLEREGDELQADAERLQRESYDFGTANVEGAMNSILRSQNLSRAAEGRVDDTQPTLDQSAAVRQEVEDLIGER
NAALESERQGYLDRLDDVDNQLTGLEGLLAGLNEEICGSPGDSCDICGGAGCGQCGGLGCGGSVQKAEDALRRATEADQK
LDQKEEEARSMLDEMMQAKDRTGEAQDLAQQAYDQALLAKQEAEQGQINIKDLINNITDFLGRSKSEPDDIRLLVNETLN
TKISLSPEEIEDLAEQIEDIIATLENIDEIIAATRDDLQRVNDLKARADAAREYAEGVLDSAEDVVRALNQAEAAQNIAD
NAINNATEDIEDAGDSLTSIESEARDAKDKSNNLLDKIEAMKAQLEGVQLKVTDNQEKVTQAVDLAEMAEGQALDVAGRV
EEMERDFNQTSDEVMAKVAEVEGAKGRADTLFLNVIAFEEKITKDYEDLQEMETTFNNNNATLHDLTAEIAALNMKMMQI
LMDIQTKAAYYRSCTESPTAP
>NP_999674.1 alpha-1 collagen precursor [Strongylocentrotus purpuratus | PB0129
MYSFVDLAVCHRRKILLTLLVLFAVQSFSNGQAAGQYSEGPRGDKGQKGEPGDADINSANFPPGLPGPVGPPGPSGPSGP
AGNNGPPGPNGPRGNPGMDGLTGLPGIPGPPGPPGKSGSLVASAQTSSFNKGPSLAGYQYPQAQAAGTPGPRGPPGPPGS
RGPQGLTGPSGPSGETGPSGNSGPPGPSGLPGRPGSDGDDGTPGSQGQRGPAGTPGSRGTPGMPGAPGMKGHQGLPGMTG
SKGERGEGGERGSDGSPGPVGAPGPAGPSGQPGERGRTGPAGSQGDRGADGATGSQGPPGSTGPAGAPGMPGISGAKGDA
GSPGARGSPGLQGARGERGSEGSQGQTGPPGVPGRDGSNGAKGSAGPSGAQGTPGFPGARGPPGPAGSPGPAGSKGDQGN
PGQPGAQGESGPLGPRGETGPAGPPGAQGESGERGSRGALGPAGPPGGVGERGPMGPPGMSGAPGAPGAKGDRGLPGERG
SAGSKGSAGESGRPGEPGMPGQRGLTGPPGKQGRDGKPGPAGAPGEPGNSGPAGASGQRGLPGLVGLPGPQGQRGERGED
GGQGSPGAPGLTGEPGKRGEPGVAGPPGPQGSAGERGNQGPQGQAGSMGPPGPPGASGDAGAQGDNGPPGESGPEGPPGA
RGERGAPGERGPQGLTGAQGRRGIGGRAGNYGATGPPGQKGEMGPPGNVGLQGPPGELGPSGPPGARGPPGPSGSPGPDG
PAGAEGDRGPVGPMGPSGPSGMPGERGDNGEPGPGGAPGQRGDPGDLGPQGSPGSPGFAGPPGRSGNPGPQGELGPTGAR
GETGGPGPSGPTGDPGPQGPLGAPGQQGERGETGPQGQGGPPGPIGSLGAPGAQGPPGPTGPSGNAGSPGQPGARGEPGQ
SGSPGQPGLAGRTGPSGERGDKGNDGQSGPPGPPGPAGPAGQSGILGLAGGSGPRGPGGPAGPPGAAGSRGPAGKSGDRG
SPGAVGPAGNPGPAGENGMPGSDGNDGAPGPQGSRGEKGDTGASGANGSPGAPGPIGAPGAAGASGPRGETGSTGAPGPL
GPTGARGSTGPAGPSGPSGPAGERGETGPAGHKGHPGVSGLPGLQGTSGPMGEPGAPGEQGQQGTRGLPGARGSNGNDGP
SGPRGFDGPEGPRGPRGEGGSSGPPGPPGPPGPPGPPGQVQSSYGVRYPSFQSGGKGQGSSPYGYAYRDDSKNDAVKIQD
TELLGAISALGQQIELIKAPQGKAKTNPARSCKDVFLNNVEAESGYYWVDPNLGCQKDAIQVYCEAETGATCVPSTNNVV
SNMTWYVGKTKRAFFSSMHGGDKFAYIEDSTQMTFLRLLSTSARQTVTYFCKNVQGNPIFLSSSDVELVDDQDSKFNYRT
LEDGCSSSSSQWGKSVYEYETKKTTRLPIVDFAPGEVGSESQMFGLEMGPVCFS
>XP_030835790.1 protein NDNF [Strongylocentrotus purpuratus | PB0130
MNSLFKPPLTFFLPLLLLVSRAKLSPSQRLPGNNPGEHAGRHPELFYENGLLPDGREMTAYAAQGTTKKFFFTVEEDNTP
VRIMVTPCSARIEWNLSMLELPEDGSGSSAADQLSEQRPRRQPTTMPGTILKSYSGYDAGKYITNTSPACTYVLEVRSVE
RGTTFQIYATSTPDSDHFFPELPSDPQVDVTSFNKNRVSLAWKPSPSDVVYHQPVRYCLAINTRRNYHTWCGVQSSVPGG
GSNPFPSSQTRFGFDSEREMRKARKQIQDEQAVLSRSEEAPDMVIECVGSKTLHTITNLDPGTRYFFDLFAVDQVTNRSV
AYLGTSIYTRAEPPDRRVIRLKDGGLRTIRGDRSSPVKQFRFPVSGKSRDQDVNITIQSCSQKLAVEIWREGVKIRDATV
KSLKHFSIRNVEDELLIKVKSRRRTPTDYKIFATTNPSKYPFPQLPKDSTIRVFKNLRQCTSVTLAWLSTKEVSQYCLYM
REEDPKSRSLIRQDNRCHGPKNRKKSEKVLCRSVNGAEADRDALTEVVTDLKAGTKYIFDVYVSGVGKETLAYRSKSVKT
KRTCDV
>XP_030841772.1 slit homolog 1 protein isoform X1 [Strongylocentrotus purpuratus | PB0131
MSGSFRPLKLIETLYLNDNNLTTLSSSSFTHMSFLKQLRLSKNPLACDCHLSWLALWLRPHIHLGLFTTCETPRQLHGLK
VAELQTSDFRCTGNENHEALCEVEPLCPAKCECTSKSVDCRNRGLTELPFTFPYHMMELRLEQNYITEIPPRAFSPYKKL
KRIDLSNNLIETIAEDAFSGLRTLNSLTLYGNHMSDLPEAIFRDLTALQLLLLNANRLTCIRINLFRDLVKLHLLSLYDN
NIRSLSNGTFDSLRSLQTLHLARNPFICDCNLRWIAEYLESNPVVETSGARCARPVRMERKRITNMKSVKFKCKDAEYYR
TAQAGQCFIDHDCPDACTCHESIVDCSNRGLPTVPDEIPTYTTELKLNGNEISRISADGKFLHLPNLKILDLRDNRISVI
EDEAFQGASSLVELMLTNNKLSNVTGRSFVGLKNLRTLMLRSNRLSCITNETFTGLKAVRLLSLYDNAISTIMPGSLDSM
KALATLNLLGNPLNCNCHLSWLPDYLSARLIITGEPRCQEPSTLQDTPIQTLQRDQFTCEGNDHNSCLPSLACPRECACS
GTVVRCSRKELTLPPRFIPTGATELYLDSNQMITVPERLSSLKSLHTLDLSMNQIAMLPDFAFANMTKLSTLILSYNRIS
CIPDGAFMGLNSLRILSLHGNNISIISESSFSDFTSLTHLALGGNPLYCDCHLHWLSDWVKDGFKEPGIASCADPYILRG
KLLLTAPSKKFLCTEEPDISIRAKCDPCLSAPCENEGVCLTDPIERYRCQCPAGFKGQHCEAEVNECDQRPCMNGGVCEN
LAGGFRCDCSTGFSGDMCEVNVDDCKAHLCLNNATCVDGINNYTCRCSQGYKGDYCEVDIDLCHPMSDPCQNGGVCFDLG
HSYRCECPPGYRGINCTDGYEDCRTRPCLNDGECEQDGNQFACRCPQGYIGQTCEMNANIYISDTPCSCLNNGQCYDNNV
TDSEECRCLPGFYGTKCEIPTSMSFRLGQEVYVQYPAPNNPQIVNFTLIFATTIENGVLLYLGNINHIAAELFRGRIRVS
YDVGNFPAATMFNQKKLNNGEFHKLQLVLYRRNVSMSIDGGPWQTKTNAGEEEYLQVDEPMYVGGLPRHLQNFAVNQWHI
RNRSSFQGCIRAFFVNNEPKRLSDASDRMSVKEGCPNYDMPNPCLENRCVNGFCHNVDESMYRCDCQDGWMGTFCDRETT
CTSIKVNNTYEMDGCQTLRPIRNATCAGECGLSCCKPARSHMRNVRLHCPDGTTITQEIKIVRNCACQGCEGG
>XP_011666177.1 leukocyte elastase inhibitor [Strongylocentrotus purpuratus | PB0132
MSEYIRNMAFYKQQDISEQLVQLSSANTRFALDLYQTFQDERRGTNLFFSPLSISTALAMTQLGACGDTATQIADVFRFN
QVDQDQLHGTFKELNNLLYQTNSGYKLHAANRLYGKSGYNFVQSFLEGTASYYGAAIEAVDNFAAPTATHSINDWVSKQT
EDKITNLIPPGILNDLTRLVLVNAIYFKGNWESKFRAENTTQETFKVLDERKKVPVSLMIQKGKFALAVDKTNDCLVLEM
PYQGRNLSLLIALPVKDDGLGNLQTKLSADILRSWDAGLKSRQVNVLLPKFKLEAEFQLKEVLKRMGMPDAFNDGKANFE
GISGDRELYISAVIHKAFVDINEEGSEAAAATAVAVKLGCARPREPEKPTLFRADHPFIFMIRHRPTKSVLFMGRMMDPS
>XP_030838020.1 laminin subunit alpha isoform X4 [Strongylocentrotus purpuratus | PB0135
MKMALGLIVKLLFAAICCVSATSHENETLVLNPPYFNIARGREIEATATCGEGFATPGEQGELYCKLTGNTADIYRPGEH
VIIQGQYCDNCDPGDPAKAHSIEYAIDGTEKWWQSPPLSRGMSFNEVNVTVNLGQLYQVAYVLIKFANSPRPGMFVLERS
RDYGETYEPWQYFAETPSDCQLEFGMQSLEEIRNDDDVICTAGYSAIVPLEDGEIVVSLVNNRPGAPHSSTLQEWIKATH
IRIRLLRTNTLLGHLMAVARQDSTITRRYYYSIKDITIGGRCACNGHAAYCDLPSSNDGRNKQVCRCEHNTCGVECESCC
PGYVQKAWRTSSYSSPFECERCNCHSHSNECVYDEEVALSRGSMDINGNMEGGGVCQNCQHNTVGVNCHLCKPGFYRPEG
RKQSDYDVCQPCMCDPILSTGNCAPLTGQCECKPEYAGPDCTECNEGYYGYPYCRPCDCNLNGTENKVCQVNGGQCPCKP
NYTGRNCNLCALSYYGFPECQRCDCNTIGSFDIVCDSENGQCSCREVYDGRSCDSCRDGHYNFPTCSDCSCSQVGTEEEV
CNKTNGECLCGENFGGQRCERCSIGFYNYPDCLPCGCDDTGSFNGQCDDSGQCPCESNFAGLKCDQCAAGFYKYPACEPC
NCDRYGSFNVLCDQVSGQCSCRPNFQGRMCQQCGESFYNYPNCEECNCDPAGVIDVPGQPLGGCGSSTGGACLCKDNVMG
RTCDTCKPLYWNLGISNPYGCEECNCNLAGTVGGMAICDIRTGQCFCKGQVTGRTCAECRDGTYQLEASNPIGCQDCNCD
VGGSVHAACDTRTGQCVCRPRVTGVTCDMPEANHFVPDLHQMKFEAEDGYTPNGRRVRFGYDSFEFPGFSYLGYAIMSAI
QPTIRIPITVESPSIYRIIMRYYYPNAGGPTRGRMTVTPADPSQVQASEQSSGIIFISTTIPQFVTVEGSGVIKPFVLNP
GSWVVTIEAPEGILIDYIVLLPSDFYEATILQEHTTEPCIVGTPQQRCNFYVFPEVDQFFVAPGVDGYSVDSNGGRYPVQ
RFGDDLIMQELGVDSMALVDDNQNIYGIDLPIFQAGRYVLIFEYYGGGPGQQSALIDVYGSQDTQQGELIFNDCAFLCRA
IVLDDDSRVQVFDIQDVMPYAQLTKIGGPYMLSISRVIAIPVESFTYDFVTPTLECVRTADGECLPSTYPVPPNTILLEG
EMNLDAPLPPNIYNPSPTVTYLSNDNQNTASYHDDLVPNSGEVVFVIHYYQPNGESYDTDFRVVGQFDGEGTFNAKYCPH
VSGCRVVVTKPDGSNVFELSDLSQGIQVTLPEGDNRQLWIDDIMVIPVEMYTPDVVNANPQDRAGEFIQYCSANDFYFSP
DSSGFCREAVFSLSSAFNYGASECDCDSQGSLSFNCDELGGQCNCRQNIVGRRCNKCAVGYYDFPYCRACTCESGVCNEV
SGECICPENVAGTNCDTCAPQTYGYHPIVGCVDCECDIRGVDNNDLNCDFFTGECNCKPNIGGRQCERCERGNYGYPYCE
PCNCDVNGTTEEICDQTTAQCLCKDNVYGDQCNQCEPGTFYLADSNPEGCISCFCFGVSTDCRSYTRRRARIDMVDGWTT
VNFDPSAVRYGSNFANIYVSGTGDTPQNAIYWNAAEKFIGNKLTSYGGKLEYTVRNNPQPAELGGAGPAQPMRRPDILIS
GNNISIMYLHIDQPDPGQDLSVSVELKENNFQYSISAAEVSRSDFMTVLANIDSLQIRAQYFDRILTADLLGVSMDVTRR
DGDGAVAQEVERCRCPPQYQGLSCELCAEGHYRLPGSGPYLGQCVPCNCNGHASRCDSKTGQCLECDHNTVGDQCESCKE
GYYGDAPSGDPDACKICSCPQPIENQNFAVTCTFSPQGDQFCICQPGHTGQYCDQCVQGYYGNPLQGQACRRCDCSGNTD
PTTGLAECDQSSGNCTNCVVQTKGRSCEDCNDWYYGDARVQSCQACSCDRCGSDSCDNFNGVCNCRPNVVGYDCERCQVG
YWNFDSCSGCLPCDCSLGAVDSQCDMETGQCTCMPGVGGDKCDACLHGYWNYGPNGCYECNCDPKLRCDPYTGECLCPPG
AMGENCDQCEDRYILTEQGCQPCDECVHLLLDIVEEMAEDLDEADRNLTDITVGVVAFQRLNNLNRSIHDLIPEVEDLDN
NNALVRGSLGNLTYQIDDLKYQAGQVEERAMAAVTNGNGTANDADILKKRAQQIEADANATIDFIHDVVEELQAIGNGTI
SSNTNLGELLARAQMILQELKDRDLNPGKGAAEEEKRLAQELLDRARALQNDSAEVGDRADEVGDDVDVFLDKLNELMAL
CENSDNTTDQVNAILDKHRNPAFEDVLAEVNAKNEMAQEEVTNATNLLDDAYGFLADARRAIDATGVNGSKLEAAIDQLE
PFIERYEEEGRNLPELVDNATDYANDLWNTAEELDRMFDSTRNLSENALKAVRAYQDIGNAIDEAERAARAALNASGLAL
DAANDFGTQPQDSKRRSKKLLRKAVEAGEDMEGSLPKASLLNQSLSLRDQLNDVEQEVEMVKDNLDAVEDGLAEIERGIA
AIPSPSSECTIITNCDATDPTCRLGYSGDNCNIANLGNLAEGAANTAMAAESIGNDAKDRADDMIDRAGDVKAKLNGLGA
TIQAANDKMASSQNSIDEIRDIEGKIPGLRDRLRMQHRLMDNMTLSMTYDLAEIQKKIAEARSLANGIKVAAKFGPDSYV
ELKAPAEVSESTPISSFSFYFTTQANDGLLYYVGGPAAGDDYLALTLENRNLVFRYNLGDDDAMATVAQDVTDGLWRYVL
VERYGRYAKVTVTTESTGDQDGESSTTGVFNLLDLQPESIMYIGGAPQSADLPGVISNRDFIGGVDEFQFGETPIGVWNF
VNASSVNEGIMRNVTDLAVTTDPDDPNSAVMFDGSGYAIVQRGTKEMSVGNRIQLQLKTLSPNGLLLFAGNEGNTFFIEM
RGGRIYYEYDLGSGPVSKISKNIYNNNKWTTITIFRVGKATQLFTITQGPISEDFAQFSSPGAETELETNNLIYIGGLVG
VPDDQFTRVTRESFRGCMANLVISSQNVDLTAADVQTAGFFPACIRQDIRVATYPGPSGGYTELAMLDDLDLMDDGDFIL
RFRTEQPNGLMLYTADDTQDSSLAIMMKDGAVLVVAHRVETAELLTPEDTYNDGMWHTINVRRPARRANASPGFDELSLS
VDDNEAVVEAFASRNMKTGGMLFVGGVPEGYDLGPITVPAAASEPFIGCLADISSKHRKITFANRMRDFNAFYGFCDLSL
SSNATEGEVTLTSPAPTSAAGPSTTPSMRNDGPCVLSSNPEDAPEDPTNEGAVQFGVLSDSRVEFPPLKSSEYSNGYDLS
VAVRTGARNGIIYYAADGSQIDLLALFLYEGRPVMVFNLGSGNLRLEPLDGRTINDAQWHTIRTFRDKTSGELYIDGELV
NSGMSTPGARLLKTTTNFFWGGLSKDLTVANNDVNEASQIGLLGCMKDLTNNGVEFGVRANEYEIQACSQIIEPGVYFGP
GKGYVIPDETFMVNQRLEVRMSIKPRVKSGVIFSVAKPGMDFASFELIDGQLFFRVENGAGKFEATYMPPEGSAFLCDGN
WHDLLVNKEGSVIRITVDGDEGDQVTGPSGATAANTNDPLYFGGIPDGEEGNHPGIERNAHYVGCMRDIMVNDDLINMAD
GIFEGDVDTRSCAAN
>XP_030835556.1 uncharacterized protein LOC578177 isoform X1 [Strongylocentrotus purpuratus | PB0136
MGSLKFVCLCLGALMCVSTLMTHVDAKLKAKKIHAPSYASKVDLVQVTEEGRHRERRDDDDDDDEDIDSDIDPVIAELNR
LLAEIRTIQDGAQVDTQGQNRAASSHRHPVRLQGGTSEYDGRVEINYEDQWYMVCDDYWGIEEATVVCNQLGFNGALEAV
QRAADEYGFNDNGFAMDDVRCTGMEPGLSECDFPEWRSHNCDKGEEVAGVRCQPERTSPNRAIRSVQGAPTIPDSSQIML
RFNVNELPPWLQSILGSKPSETSTPGSATGGTVAGSSGATGSDGSSQVPVTRARDPECFTMSNGQDYRGVVRQTISGYAC
QRWNVQTPHGHSYTPAQYPGILGNHNHCRNPGTFSQPWCYTTNPRIIREYCDVGNPRTSCATTAQTVQGNGEATTYLSEY
ALVPAAYLGGNNDGTHSVATAELCAERCNKERSFVCRSFEYNEQSNECLTSSSNSRDVDLTFLLSTRFNYYERLDIGPIA
LFDITPNSAMPGNNIESLTAVSMEECAERCLVAAWPCASFDFARRANRCWLSNKSPSQVSIRSDFPDNPYDFFSRRGPAT
PNCYLGTGENYRGFSFTTTQGHQCTNWQAAAMDNVGVTPVLFPDGDIGNHNFCRNPDSDRRPWCYYKDSGSSTVSGWMYC
NISTCETSTAPPTSRPTARPPPPTQAPSGPIPVSRGKPAFQSSTHTSGGIMANAGLAVDGNPNPSFDQGSCSRTQSRANS
WWYIDLEAAYDVTTVVIVNKDVQGERLRGAMVTIGSSATDPSTRTQCGRITRTMTNAASRTPHQRIRIDCPSPIRGQYVH
IGSPRKDYLSFCEVEVYGRPSSPPTPAPEPTVSCTAAEFECASGSVSCVPERFQCNGQSDCTDGSDETGCPDPMDDFTII
ADKYLPNREPAVIYMEKTADECARFCVSAMTFVCRSFDYNSAERTCSLFNVSRSQNGRLFSRQGTAHYERISQTTDCTNA
NGIEYHPCPSGRCIPNEWLCDGDNDCGDFTDESNCGTLEEFEVRIVNGTAPNEGRVEVKYRGKWGLVCDDEWDLSDGHVV
CRQLGYTRGASDVYIVGEFGHGNLVDIFMDDVRCTGNEQSLADCPHPGWGVNNCVVGEAAGVLCKLNQDCPANHFECNNL
KCIPEGNVCNDMDNCNDGSDELNCQPELPVLPVRLVGGNGRTSGRVEVFHNNQWGTVCDDYFSEAAARVVCNQLGISGDV
QVYPQAIFGEGTTQIWLDDVTCAGTEPSLAQCTIPNGIGRHNCQHNEDVGVECGRETLPCGVRGIENGNIMARIIGGSSA
KRGNWPWQAQLILRGSGHYCGGTLIDETHVLTAAHCFQRYGKNSFKVRLGEHHQHINESSEQDFRISCIYKHPDYDSRTT
NNDIAVLRLDRPAHITSFVTPACLPTDGEFAADHQCWISGWGNTGNDNYPSRLQEARVPLLPRSTCTRQNVYGNKLTPQM
LCAGYLRGGIDSCDGDSGGPLVCENSNSVWKVVGVTSWGYGCAQPNAPGVYAVVTRYLGFINEKMITRTCT
>XP_030855712.1 alpha-1 collagen isoform X3 [Strongylocentrotus purpuratus | PB0137
MYSFVDLAVCHRRKILLTLLVLFAVQSFSNGQAVTITNLDVMLSNPAPISEGQVNSVPVDVNIDLLNRKTQDVSGTGLWK
LQVWGSLRADGVGQQISLSEQALTRNQEATPVERGAPFFFRNVPYELDMRGVSCSEINYVCVRIRKGNDPDPQFTFKGKP
NQATTFSDCAPISECSGVQLRGLTWELQASNVIAGMRNPLNITAQVNFVEGAGDVSGENLWRLGLYGSRNAQGSGEKFNY
VRQTLNEFESAYPLRGAGDINFRFARAAFDLAAIGCTDYDYMCGEFTKADNPNPDFSFSVYPSGMTKITCKGWPCRAVVN
IEAVSAIPVRGSLVAGRADNPIEMYVKVNGSGVGVAGQNLWTLSSYGSQNSRGAGRKYAQTMQILTPEQQNTMLVPGTPM
ELGRVSMNIDMTNQDCNQVTHVCLTLGKGQNPTTVFSVVPVPNSNVLTKCIPYQCAVATARSLSWDYDAPTVVLGQQSDL
TINTEVSFVDNEASVVGSNLWKLGIFGSRNLNGRGQRIGEKRQILRTNEASTPLDPRTADGLHRLNINNIRTTFDMSSIG
CGAFPYLCVEFGQADRPRPSFEFATEDGTDSVVNCKLLQCENDVMLNELHLTLENGRILDARPENPLTFSLEGSLIGPGV
QGRDLWTVSMFGSGEPDGVGPRFGQMDQILDTRQRNKPYVPNENLDFGNIDLNFDMSSHECARIRYMCVEFSKNDQTSVP
FTLTASSGEAWISCVDIPCEGVIASDLIWHYQAPEGITLGAPIPILLDAVVEFSSVSADVIGRNLWALTLYGNTMESGRG
DIIGILEGNILGNKAASRNLLVGDDSLNFTNVRSEKDLSRIGCLHEGYLCLTFGRGANPKPPFMLLTTSGGDSIVSCKKV
PCPRNVELTNIDTGFVSGSLIEGTPSNEIVLSMTANSAPNSNGINGISLWSVGAWGSRNPDGSGKRINPVEGEVLSGAQS
SINLTPGGMIDFGEVAIDYSMEDVTCRDINYICVELDKNSGSNVEFNLIAERETMRRCEAVSCSGVLARTLSWDFRANEV
RPNQRSPITVQASVRFDENSSPLTGSRLWRMSLFGSDNLDGNGRTFDPIHQILDAQNQRKSLNPQFPLTFNNVPTEYNVG
AIGCGEYQFLCMEFTRADNSDPAFVFDVVGGGNKLVNCKQLLCNSDVVLQGMTTNIVGSPIVTEGIRNTVDIDTSVFSSP
ESRPLDSSPGLWQLSAYLTPSPDSPLQFNVQNQVLSRQQASSALNPGSPIGFGPVSVNVDLRQTTCEQAGYVCTRLSKGP
SPRVDFNLQIVPDPSAVKSCERIECNGVHLQNNIDWTYNADDSIPGRETPISITTNLLPFPNSRDITGNDLWEMGLYGSK
NPDGSGEKFNYEDQILSPEQAGTPLDGDTPFFLDNIDTNFDVGSVGCTDFRYLCVDFKKGRNPSTDFTFQIGDTAENTIT
SCKRMACDSNAIVSDLVSTLGSDAILIEGNPRNGLAVDLRAITSLESTPILGDRLWQVDSFLSRNPDGSGREGALNTNIL
DPLQSAWPLRPGIDIDYGQVLVDVNMQDVSCAEARYMCFRLRRNADATVSFNLQGEPDDSVLTSCLDMTQQCQGVILTGI
DWSYDESVPRTLSISASADVTLNSRNLDGSGLWTMGLFGSTNGRGLGNRLGHQQQILNLYNQGRTVMPPRPITFRNIDTR
FNIEQLGCNSQYQYLCLELSKGANPNPEFSFRTIDGDDSLMSCKQRECRAVIITGQETTPSAFRLREGEPVNEINLATVV
STAREGGTVTGDQLWRLGFYGSTNPDGTGQRVGYQEQILPYYHADQDLERPGDTIDFSGLNANFDMTSIPCSQVQYLCTV
LSKNPEASDDFTLTTQPNEDVLTSCFPVPSGACRGVIVTDMEWSYTSSKPIPSQPDVLEIDMSVDSLETASGIDGRRMWR
VGIFASKRRDGTGPRQGTNYQILNTFQARKPLVAGQRLNIDTIATRFDLDEINCDSGYRYLCLEFAKSMRPLPDFEFTTT
TGGNTIIRCKEYECDRGVKLMDLETIPDTNYQTVISQKRENILQFDMMAAPASDTAALRGVNLWELALWGSDNPIGEGPR
HNERTAYNLNTYQKSVAVTNQDVLRFGTVETTFDMTGLTCDEVQYICARLQKSSDAVPNFQLSGVPNNRVLTQCFNVRCA
GVVVDNTRLSVSSSSLTDGSDEVFFSVTMNSQDQSADAALENMWQMSAYLTSTSDGTGKRVVLGEEILTPRESSQALFSG
SRTGFYDMRTRVNRDTLDCTASNYLCIEVTRASNAPNTFSFTGSQANSLSSCERLECAKKPAGQYSEGPRGDKGQKGEPG
DADINSANFPPGLPGPVGPPGPSGPSGPAGNNGPPGPNGPRGNPGMDGLTGLPGIPGPPGPPGKSGSLVASAQTSSFNKG
PSLAGYQYPQAQAAGTPGPRGPPGPPGSRGPQGLTGPSGPSGETGPSGNSGPPGPSGLPGRPGSDGDDGTPGSQGQRGPA
GTPGSRGTPGMPGAPGMKGHQGLPGMTGSKGERGEGGERGSDGSPGPVGAPGPAGPSGQPGERGRTGPAGSQGDRGADGA
TGSQGPPGSTGPAGAPGMPGISGAKGDAGSPGARGSPGLQGARGERGSEGSQGQTGPPGVPGRDGSNGAKGSAGPSGAQG
TPGFPGARGPPGPAGSPGPAGSKGDQGNPGQPGAQGESGPLGPRGETGPAGPPGAQGESGERGSRGSVGPAGPPGGVGER
GPMGPPGMSGAPGAPGAKGDRGLPGERGSAGSKGSAGESGRPGEPGMPGQRGLTGPPGKQGRDGKPGPAGAPGEPGNSGP
AGASGQRGLPGLVGLPGPQGQRGERGEDGGQGSPGAPGLTGEPGKRGEPGVAGPPGPQGSAGERGNQGPQGQAGSMGPPG
PPGASGDAGAQGDNGPPGESGPQGPPGARGERGAPGERGPQGLTGAQGRRGIGGRAGNDGATGPPGQKGEMGPPGNVGLQ
GPPGELGPSGPPGARGPPGPSGSPGPDGPAGAEGDRGPVGPMGPSGPSGMPGERGDNGEPGPGGAPGQRGDPGDQGPQGS
PGSPGFAGPPGEAGSRGPAGKSGDRGSPGAVGPAGNPGPAGENGMPGSDGNDGAPGPQGSRGEKGDTGASGANGSPGAPG
PIGAPGAAGASGPRGETGSTGAPGPQGPTGARGSTGPAGPSGPSGPAGERGETGPAGHKGHPGVSGLPGLQGTSGPMGEP
GAPGEQGQQGTRGLPGARGSNGNDGPSGPRGFDGPEGPRGPRGEGGSSGPPGPPGPPGPPGPPGQVQSSYGVRYPSFQSG
GKGQGSSPYGYAYRDDSKNDAVKIQDTELLGAISALGQQIELIKAPQGKAKTNPARSCKDVFLNNVEAESGYYWVDPNLG
CQKDAIQVYCEAETGATCVPSTNNVVSNMTWYVGKTKRAFFSSMHGGDKFAYIEDSTQMTFLRLLSTSARQTVTYFCKNV
QGNPIFLSSSDVELVDDQDSKFNYRTLEDGCSSSSSQWGKSVYEYETKKTTRLPIVDFAPGEVGSESQMFGLEMGPVCFS
>XP_011672270.1 protein artichoke-like [Strongylocentrotus purpuratus | PB0138
MARQQIATKRQCTLLPNLFIILLIVTVSGGTVEQCPKETECICQSLRMVNPTVIVRCQQELVEEFPTMRQKVVAFYAFQT
RATALSLRSFRNATNLGMISVVDNPISSIEDGVLSSLPNLVFLVLANIKLKGTSDLNGLRALTELTLSDNLLRNFTTSSL
LDLPQLDVLELDGNFITTFRFSHDKLRVLNLSRNNLQDFHEESFKNLRMLDILDLSRNSIVHLRNIASQSLHSLFLAYNQ
IVDIDGTMWQELPVLKSIDLSNNRIRDLSNVSGLPFLKNLNASGNLIESFDSIHPSATLVNLNLSHNRMKNLSKMPDFPL
LESLCMAKNAIEYFDGNALQNSPLLSFLSLEGNRLAEFGALSNNPRLVSLYLQNNMIDDIEEGAFTRSASLEDIDVGSNK
LSDLQEFKNMPSLVYLNASGNMIMEISGQSLQGCTKLSILDLSENLLEEFPNFPVVYWPFQLYLDSNPIRVFDWNKLRNL
YSLRRLSLNGTRITYIPPNSHFFPTTHISIKNYNASVTIADNALTALISLRELSVPNVAEVSPRIFRSAHNLKRLELRSG
ELSEITTEWQFVSLDYFDLSQNRIHGIDIDGRSMTRLKSMILTDNLITNVSFVNYLPNLRELYLRHNRIWHIPKDAFTSC
SALTVLDLSYNMIEEVIIGTFDYLRALGELYVSYNMLTDFSLAFDTNTDSSHEFKSINGVHLEGNRISKIDSMTFQSCGY
SLRRINLAHNPLRLINETTFLRSFGLRTLDLSHTDLQSLTAGLFRNVGYKSDLVVSLNNVTCLKDMDIISLTYPKRKVIK
RLELRNNNLTRIPSFNNSIVVELDVSHNNLSDDYYRDLSGTEDLKFLDVSVNNIEELDRDFIQTFPRLKHLNVSSNKLQQ
AQHNLFDSLHNLETIDLTNNKLDGIVLKTTENLKANVRINLTGNPILCDCSLVKYRAHLKQSQQLSGHDVPEGDVTCQYP
PRLSGEYVTDVPLEQFQCKPEVNPSKAVVFGVVGDPIRLECPLRDRNGITVTWENVTEIHSDKHIRVSTDGRLMIEQMTT
EDSGNYQCNATNQEGSEILIVQLHVGLNPIVNDTTSSDVISRLAMTVTESLSSYIQFSPETFEGPSDLPGDHPEARQETV
NDESIPRLPRRSQAVSMELSMLCVMLNAMVVITL
>XP_030837276.1 collagen alpha-1(IV) chain-like [Strongylocentrotus purpuratus | PB0140
MSSVDVCCSHVFILFAGISGFPGFEGQRGDRGDYGPDGFPGGPGLRGENTQGPPGLPGPQGPDGRPGRKGQPGSLGAKGE
RGFTGEFGLRGEPGDPGVPGVPGRKFNGYNGRPGRGGSPGSLGPRGEIGDPGPGGVNGPPGPPGIIGVRGVPGDLGDLGP
SGFPGFQGRPGQNGMFGNRGPRGLSGGPGDAGYPGFQGMEGSRGFDGNPGPEGNIGNPGPSGRVGEPGIPGADGFPGGPG
LAGADGERGQMGGIGDVGPPGPGGEPGPRGDFGTPGIPGNSGLVGLPGRRGETGPDGPSGETGPLGIKGYPGNPGRNGFP
GLRGARGEKGDDPEIRIPTEVNRGEAGAPGDPGPTGLGGIVGDVGPQGGNGFPGRRGIPGIEGPPGPEGEPGLPGLVGFR
GPIGEDGPKGGPGPNGETGESGLKGFPGYNGIRGQKGNSGRGGFPGFPGEPGGAGEIGSQGPRGAKGYPGLKGDRGITAP
IGSRGEPGTPGTPGGPGERGYLGRPGFEGPKGLQGMKGDLGEQGQPGPLPPDLGPGPQGMQGVPGIPGLRGYKGFVGDFG
VIGVIGEKGTKGRPGIFGLKGAPGPPGQPGFNGVKGDGGDPGLAQKGLKGEQGEQGFAGFPGRIGLPGIDGPLGPPGPKG
RDGLFGDFGPSGLPGRNGEPGMPGFPGDSGESGYGGRPGSPGPKGMGGNTGIRPNRGHFITRHSQSRNVPSCPAGTVELW
RGFSVLFSMGNGHAHHQDLGDAGSCLQRFSTMPFLFCNFNNVCNYASRNDRSYWLTTNEPLPMMPLMNQQIDPYISRCTV
CEAPTQSLAIHSQSQEIPQCPGGWRSLWTGYSFTMYTAASEGGGQGLESVGSCLENFRATPFIECNGRGNCHFFSNEYSF
WLTVIDEEDQFAIPRKRTIKSGQLQSVVSRCRVCQKVN
>XP_030838005.1 laminin subunit alpha isoform X2 [Strongylocentrotus purpuratus | PB0141
MKMALGLIVKLLFAAICCVSATSHENETLVLNPPYFNIARGREIEATATCGEGFATPGEQGELYCKLTGNTADIYRPGEH
VIIQGQYCDNCDPGDPAKAHSIEYAIDGTEKWWQSPPLSRGMSFNEVNVTVNLGQLYQVAYVLIKFANSPRPGMFVLERS
RDYGETYEPWQYFAETPSDCQLEFGMQSLEEIRNDDDVICTAGYSAIVPLEDGEIVVSLVNNRPGAPHSSTLQEWIKATH
IRIRLLRTNTLLGHLMAVARQDSTITRRYYYSIKDITIGGRCACNGHAAYCDLPSSNDGRNKQVCRCEHNTCGVECESCC
PGYVQKAWRTSSYSSPFECERCNCHSHSNECVYDEEVALSRGSMDINGNMEGGGVCQNCQHNTVGVNCHLCKPGFYRPEG
RKQSDYDVCQPCMCDPILSTGNCAPLTGQCECKPEYAGPDCTECNEGYYGYPYCRPCDCNLNGTENKVCQVNGGQCPCKP
NYTGRNCNLCALSYYGFPECQRCDCNTIGSFDIVCDSENGQCSCREVYDGRSCDSCRDGHYNFPTCSDCSCSQVGTEEEV
CNKTNGECLCGENFGGQRCERCSIGFYNYPDCLPCGCDDTGSFNGQCDDSGQCPCESNFAGLKCDQCAAGFYKYPACEPC
NCDRYGSFNVLCDQVSGQCSCRPNFQGRMCQQCGESFYNYPNCEECNCDPAGVIDVPGQPLGGCGSSTGGACLCKDNVMG
RTCDTCKPLYWNLGISNPYGCEECNCNLAGTVGGMAICDIAHAPWHKRTGQCFCKGQVTGRTCAECRDGTYQLEASNPIG
CQDCNCDVGGSVHAACDTRTGQCVCRPRVTGVTCDMPEANHFVPDLHQMKFEAEDGYTPNGRRVRFGYDSFEFPGFSYLG
YAIMSAIQPTIRIPITVESPSIYRIIMRYYYPNAGGPTRGRMTVTPADPSQVQASEQSSGIIFISTTIPQFVTVEGSGVI
KPFVLNPGSWVVTIEAPEGILIDYIVLLPSDFYEATILQEHTTEPCIVGTPQQRCNFYVFPEVDQFFVAPGVDGYSVDSN
GGRYPVQRFGDDLIMQELGVDSMALVDDNQNIYGIDLPIFQAGRYVLIFEYYGGGPGQQSALIDVYGSQDTQQGELIFND
CAFLCRAIVLDDDSRVQVFDIQDVMPYAQLTKIGGPYMLSISRVIAIPVESFTYDFVTPTLECVRTADGECLPSTYPVPP
NTILLEGEMNLDAPLPPNIYNPSPTVTYLSNDNQNTASYHDDLVPNSGEVVFVIHYYQPNGESYDTDFRVVGQFDGEGTF
NAKYCPHVSGCRVVVTKPDGSNVFELSDLSQGIQVTLPEGDNRQLWIDDIMVIPVEMYTPDVVNANPQDRAGEFIQYCSA
NDFYFSPDSSGFCREAVFSLSSAFNYGASECDCDSQGSLSFNCDELGGQCNCRQNIVGRRCNKCAVGYYDFPYCRACTCE
SGVCNEVSGECICPENVAGTNCDTCAPQTYGYHPIVGCVDCECDIRGVDNNDLNCDFFTGECNCKPNIGGRQCERCERGN
YGYPYCEPCNCDVNGTTEEICDQTTAQCLCKDNVYGDQCNQCEPGTFYLADSNPEGCISCFCFGVSTDCRSYTRRRARID
MVDGWTTVNFDPSAVRYGSNFANIYVSGTGDTPQNAIYWNAAEKFIGNKLTSYGGKLEYTVRNNPQPAELGGAGPAQPMR
RPDILISGNNISIMYLHIDQPDPGQDLSVSVELKENNFQYSISAAEVSRSDFMTVLANIDSLQIRAQYFDRILTADLLGV
SMDVTRRDGDGAVAQEVERCRCPPQYQGLSCELCAEGHYRLPGSGPYLGQCVPCNCNGHASRCDSKTGQCLECDHNTVGD
QCESCKEGYYGDAPSGDPDACKICSCPQPIENQNFAVTCTFSPQGDQFCICQPGHTGQYCDQCVQGYYGNPLQGQACRRC
DCSGNTDPTTGLAECDQSSGNCTNCVVQTKGRSCEDCNDWYYGDARVQSCQACSCDRCGSDSCDNFNGVCNCRPNVVGYD
CERCQVGYWNFDSCSGCLPCDCSLGAVDSQCDMETGQCTCMPGVGGDKCDACLHGYWNYGPNGCYECNCDPKLRCDPYTG
ECLCPPGAMGENCDQCEDRYILTEQGCQPCDECVHLLLDIVEEMAEDLDEADRNLTDITVGVVAFQRLNNLNRSIHDLIP
EVEDLDNNNALVRGSLGNLTYQIDDLKYQAGQVEERAMAAVTNGNGTANDADILKKRAQQIEADANATIDFIHDVVEELQ
AIGNGTISSNTNLGELLARAQMILQELKDRDLNPGKGAAEEEKRLAQELLDRARALQNDSAEVGDRADEVGDDVDVFLDK
LNELMALCENSDNTTDQVNAILDKHRNPAFEDVLAEVNAKNEMAQEEVTNATNLLDDAYGFLADARRAIDATGVNGSKLE
AAIDQLEPFIERYEEEGRNLPELVDNATDYANDLWNTAEELDRMFDSTRNLSENALKAVRAYQDIGNAIDEAERAARAAL
NASGLALDAANDFGTQPQDSKRRSKKLLRKAVEAGEDMEGSLPKASLLNQSLSLRDQLNDVEQEVEMVKDNLDAVEDGLA
EIERGIAAIPSPSSECTIITNCDATDPTCRLGYSGDNCNIANLGNLAEGAANTAMAAESIGNDAKDRADDMIDRAGDVKA
KLNGLGATIQAANDKMASSQNSIDEIRDIEGKIPGLRDRLRMQHRLMDNMTLSMTYDLAEIQKKIAEARSLANGIKVAAK
FGPDSYVELKAPAEVSESTPISSFSFYFTTQANDGLLYYVGGPAAGDDYLALTLENRNLVFRYNLGDDDAMATVAQDVTD
GLWRYVLVERYGRYAKVTVTTESTGDQDGESSTTGVFNLLDLQPESIMYIGGAPQSADLPGVISNRDFIGGVDEFQFGET
PIGVWNFVNASSVNEGIMRNVTDLAVTTDPDDPNSAVMFDGSGYAIVQRGTKEMSVGNRIQLQLKTLSPNGLLLFAGNEG
NTFFIEMRGGRIYYEYDLGSGPVSKISKNIYNNNKWTTITIFRVGKATQLFTITQGPISEDFAQFSSPGAETELETNNLI
YIGGLVGVPDDQFTRVTRESFRGCMANLVISSQNVDLTAADVQTAGFFPACIRQDIRVATYPGPSGGYTELAMLDDLDLM
DDGDFILRFRTEQPNGLMLYTADDTQDSSLAIMMKDGAVLVVAHRVETAELLTPEDTYNDGMWHTINVRRPARRANARLS
LSVDDNEAVVEAFASRNMKTGGMLFVGGVPEGYDLGPITVPAAASEPFIGCLADISSKHRKITFANRMRDFNAFYGFCDL
SLSSNATEGEVTLTSPAPTSAAGPSTTPSMRNDGPCVLSSNPEDAPEDPTNEGAVQFGVLSDSRVEFPPLKSSEYSNGYD
LSVAVRTGARNGIIYYAADGSQIDLLALFLYEGRPVMVFNLGSGNLRLEPLDGRTINDAQWHTIRTFRDKTSGELYIDGE
LVNSGMSTPGARLLKTTTNFFWGGLSKDLTVANNDVNEASQIGLLGCMKDLTNNGVEFGVRANEYEIQACSQIIEPGVYF
GPGKGYVIPDETFMVNQRLEVRMSIKPRVKSGVIFSVAKPGMDFASFELIDGQLFFRVENGAGKFEATYMPPEGSAFLCD
GNWHDLLVNKEGSVIRITVDGDEGDQVTGPSGATAANTNDPLYFGGIPDGEEGNHPGIERNAHYVGCMRDIMVNDDLINM
ADGIFEGDVDTRSCAAN
>XP_030843083.1 agrin isoform X2 [Strongylocentrotus purpuratus | PB0142
MVLCIFGAVCEENEQGRPQCICDRQCPDMMAPVCGSDGTTYLSECFLDKASCEQKKRVYVASQGSCDEQDPCEGVQCSFG
SECMIEGDRATCECPNACLSIYSPVCGSDGVSYGNTCEMEAASCRQQKEITLVNEGMCVEVDPCDNVTCNFGASCVVEGA
VASCLCPEICLESYNPVCGSDGVDYNNECDLNAAACSQQKSVTVVFQGLCDPCQEVEYENSVCKLDRNREPQPGCDSNCP
NSVINPVCGSDGVTYDNDCEINRAACLSNLEDILITFTEGPCEDGTHPCEEFTCDYGQCLVDDAGMPQCVCTPCPEVFTP
VCGSDGLTHSSMCHMEEASCMERTDITLAKEGVCDGSNIIGCQTPACNKTEGAVSPVCGTDGNNYPGLCALQEAACEAGI
DIQVAINGPCESCETTNCSHGSFCQMTPDGPTCTCSDHCQTINLPVCGSDGETYASECKLNVMACNARKNITVVSYGACE
DCVGVTCETERFNQVCYQGMCVCQESCPMSRSDEDMVCGSDQVTYDTVCHLKMSACQAESNLTVEYYGPCDEFSGSGTEF
PDYSGSGATPPNEFEFDLCDETSCSFGGICRPLSADTYECICKFNCPAVRLPVCGSDGATYGNECQLKEAACEQQSSIVL
EKIGTCEDVEMEPCDGESPLVNEATMEAYTCQEDNGGEDCPSGSYCHIHPLGRFSACCAEQTSQPSCVESVFGCCPDNQT
EALGSNGEGCPSVCNCNPLGSYSVYCEPSNLQCPCKPGVGGKQCDRCEPGYYDFLSLERNGIGCKTCGCSSYGSRRDDCD
QTSGACRCRRKAIGLKCNMCPEGLTMTPMGCMTEEEQMMTSAITCSNLTCPFSAQCQESTVEGQNATCVCPTSSSCNTDV
IQVVCGDNGETYPSRCQLQVFACKEQRNIMVQNEGACETVIVTPNEIRPGCEESQFRCCPDQVTYATGPNNEGCSDASGT
PPLAADQNAGQASASSPAPPSATTVALTTDAVVPSTKVSSTTLSVAPFVSTALPTDSVLPTTTIVTIVLGCDSSPCQHGG
TCQNDEIAPGFRCICPLGKGGPVCNEVVTFTTPSFAGDSYLAYPEMDAFMEVEIVIEFQPGATEGVLLYEAQTAEGNGDF
ISLAIVNNQVEFRFLATDQSNGFDLGSAEPVVITSTVDLQLMTWHRLRAYRSRREGSLSVDGEPEVTGTSEGVSGALNLG
EDLFIGYAVPPEVGLRLANTNQGFVGCIRYVEINSQELDISSSGSSVEYGANVGECGNDPCQSKEMPCFNNGLCEALNAE
SYRCICQGDFFGTLCGDVLVDQCEGHMCHEESTCVALPEGGYRCDCPDGRMGDMCTEEINKVVVPGFAGNSYMQLPSLMM
PDDSVIDVEFLTSSPDGVIFYNGQTADGRGDFISLNMRDGYLEFRYDLGSSIAEIKSVDRLALNEWHAVRVIRMGKSGEM
ILNDLPPVKGTSPPGASQLNLRQPLFIGGVRSYGEVSRRAAITDGLNGAVRRFVVNEVDYSTLKDFAEAKVNVEEFREDT
MNMIPTAPRKLPEMPVTTPRPPVVATRARPAMTTASVVVINTDDPLRFDGQTSIQYYNGVSKKQRALRTHQVQLSFKTAE
PNGALFWNGVGNADFQAVGVSDGYVEYAYNLGRGITRIRTTQKVDNNKWHTVIITRNLIDASLQVDNEEPVMGQSRAGAS
QLDTDGFLYLGQGVNVPGSMESSYTYYTGCIQDVLLDEVPLHLYENAQGEKPSLFCSEP
>XP_030841773.1 slit homolog 1 protein isoform X2 [Strongylocentrotus purpuratus | PB0143
MSGSFRPLKLIETLYLNDNNLTTLSSSSFTHMSFLKQLRLSKNPLACDCHLSWLALWLRPHIHLGLFTTCETPRQLHGLK
VAELQTSDFRCTGNENHEALCEVEPLCPAKCECTSKSVDCRNRGLTELPFTFPYHMMELRLEQNYITEIPPRAFSPYKKL
KRIDLSNNLIETIAEDAFSGLRTLNSLTLYGNHMSDLPEAIFRDLTALQLLLLNANRLTCIRINLFRDLVKLHLLSLYDN
NIRSLSNGTFDSLRSLQTLHLARNPFICDCNLRWIAEYLESNPVVETSGARCARPVRMERKRITNMKSVKFKCKDAEYYR
TAQAGQCFIDHDCPDACTCHESIVDCSNRGLPTVPDEIPTYTTELKLNGNEISRISADGKFLHLPNLKILDLRDNRISVI
EDEAFQGASSLVELMLRSNRLSCITNETFTGLKAVRLLSLYDNAISTIMPGSLDSMKALATLNLLGNPLNCNCHLSWLPD
YLSARLIITGEPRCQEPSTLQDTPIQTLQRDQFTCEGNDHNSCLPSLACPRECACSGTVVRCSRKELTLPPRFIPTGATE
LYLDSNQMITVPERLSSLKSLHTLDLSMNQIAMLPDFAFANMTKLSTLILSYNRISCIPDGAFMGLNSLRILSLHGNNIS
IISESSFSDFTSLTHLALGGNPLYCDCHLHWLSDWVKDGFKEPGIASCADPYILRGKLLLTAPSKKFLCTEEPDISIRAK
CDPCLSAPCENEGVCLTDPIERYRCQCPAGFKGQHCEAEVNECDQRPCMNGGVCENLAGGFRCDCSTGFSGDMCEVNVDD
CKAHLCLNNATCVDGINNYTCRCSQGYKGDYCEVDIDLCHPMSDPCQNGGVCFDLGHSYRCECPPGYRGINCTDGYEDCR
TRPCLNDGECEQDGNQFACRCPQGYIGQTCEMNANIYISDTPCSCLNNGQCYDNNVTDSEECRCLPGFYGTKCEIPTSMS
FRLGQEVYVQYPAPNNPQIVNFTLIFATTIENGVLLYLGNINHIAAELFRGRIRVSYDVGNFPAATMFNQKKLNNGEFHK
LQLVLYRRNVSMSIDGGPWQTKTNAGEEEYLQVDEPMYVGGLPRHLQNFAVNQWHIRNRSSFQGCIRAFFVNNEPKRLSD
ASDRMSVKEGCPNYDMPNPCLENRCVNGFCHNVDESMYRCDCQDGWMGTFCDRETTCTSIKVNNTYEMDGCQTLRPIRNA
TCAGECGLSCCKPARSHMRNVRLHCPDGTTITQEIKIVRNCACQGCEGG

>XP_003728278.2 group XIIB secretory phospholipase A2-like protein [Strongylocentrotus purpuratus | PB0144
MIFSMVPTRIIDQDLVLPTILVVIVHLVTASALSPGSAGSSSVESLAMEDFQHLTDKLTHKLMQDIGKLKAEDPNWPGKP
PAQMSEDDVMEEQMKATSECEFHCPKGRVQEQNPDFKMPAFKNCRLYDSSWDRIPGASGCCARHQICYHTCARERKQCDM
EFHMCIENICVELEEKGIIKTEKVVKSCHSAMGMLGIMIMEPGCKMFPKAQDAACRCVKKKPDLKIGVDSKPDDLNISDN
TISLRT
>XP_011679764.2 collagen alpha-1(I) chain [Strongylocentrotus purpuratus | PB0145
MAKSRFPWLTCGLFFLLVLIRKVHLSAIYPNNTTEYEAATKSHKYETFTAAPFTAAPDVTESSSSSTRRKDVTTSSPSPS
TQLPTSNTPYANATETYWEELPTIEVEFTTELTFTETVTEIVVEGEESYDIRTHAPASGGLKQYTANSNVSLSQGVDKGR
TLQNGSGLFLSEDVLSTDATPTLATRRPSLPKDSPETLIALTEAAWGRLGFTREAMDSPLGEFFKYYSVFPYADEKGFTR
TWNIRGDQGPRGHPGRRGPMGSMGYYGNRGPPGEKGRQGSPGPDGETGRRGYRGETGPLGYHGNHGQPGFPGIKGERGHP
GIHGYSPKEGPKGHAGIPGPQGLLGPPGEKGDIGPAGGRGEKGTLGLRGEQGHPGPQGVEGPQGIHGVGGSTGPKGSSGD
KGAPGPVGPPGEIGNDGSMGPSGLPGQRGFQGFPGIRGSPGKPGLDGQPGMNGYPGNVGPQGEDGAIGPIGESGPIGTHG
PKGQPGDQGLQGSKGEKGSRGRRGSQGDEGHRGPPGDLGMPGQAGETGDEGVAGEEGDDGVPGRKGDHGPRGLIGETGVK
GPPGPHGSKGPRGANGPRGELGPKGQTGDQGRPGGHGHRGPEGSKGKDGRRGKKGDEGDQGGKGEHGIPGVSGEKGAVGP
PGRIGTTGPVGPAGDGGIPGRNGPPGLKGHQGFDGSPGSPGPPGPMGPEGNTGQKGRPGQAGDPGAVGIQGHGGENGPTG
LPGRKGSTGEPGLLGPAGEQGGRGQKGTTGEKGSVGKRGIDGALGDEGPAGGEGIDGLPGPPGSHGKIGLMGLPGIPGYF
GQSGGKGEKGEKGKVGSDGRDGDRGSRGTRGPHGELGKQGSAGNKGLPGIQGLQADRGDSGDSGPTGSYGVTGEKGMPGF
KGESGIVGKPGHNGYSGDKGATGERGRKGDPGYRGNQGPIGRQGINGERGDSGPAGERGLHGLHGTPGEPGTAGYQGTQG
TKGEDGDQGPTGQLGEGGTAGTSGYIGVPGPAGGPGEPGLAGDDGAIGEDGLPGPQGPFGLPGNLGHHGPPGPKGPLGPQ
GPQGLMGETGLLGEKGLPGTRGRPGSKGQQGTNGWIGEAGSPSPPGLPGTDAPKGQQGTPGLEGVKGSLGYAGRNGERGP
RGPPGETGETGNSGPRGFTGQIGLTGTSGNQGEMGPEGPKGPLGNLGDQGGNGEPGILGLQGFKGPPGYLGDVGDLGFRG
VKGRIGEAGSIGARGPAGFPGLQGILGQFGIQGPRGDMGEKGRLGDPGYPGPPGSPGGYVGEFVNDADALASLLHYFFVL
PRPKHIGDVDVIHMMKYLYRYIEGMKHPLGTQDLPVRTCRDLLDCQPDMDDGEYWIDPDLGCCTDAVKVYCGLAAGGYTC
LLSRDTSTLDYDISKPQLNFLHLLSSTAFQEITIHCKNVPVWRNRRGGYENALTFRGWNGVFFSYTGQRPEILEDNCQLE
DSKWRTTRFVFRVHDVHRLPIVDIVTDPEVHRISENHGFKIEIGHTCFD
>XP_030832707.1 cartilage oligomeric matrix protein isoform X1 [Strongylocentrotus purpuratus | PB0146
MQFGTCSIAFLLMLSVTSSQIPVSMGVEADLFDGFGIYNSRIPGVSPAPQENSNIYGDAFFFNGISIRYPIIANQEFFKK
FAKEMRKNEDVYFVIRSRLAPRHHGVLFGVYSSNYYSQDTFRTPLRFELSYNGTNGGKLVLKYRVGDQQRQAEFPNLLVV
DGDWHTIILQFHTERSSTTLTLYVDCRLANQMKIGDKLSRVFSRTVIDGSEMRLGQAGYGMTANPLKGTIQNVRFMYGGP
IGDVLHSLSCSLSTEPKPLDADGWPGATILMDAFQSLSSTLMVLKNGMDDQTREIRHLRNTLENCRMCERTDYFTSGPQT
IITHGCSSNPCFPDVMCFDEPDGLGYRCGPCPAGYRGNGSYCYDINECIEAYPCSDVVECINLVPGFRCPPCPEGFIGLG
LEGIGLEAAVRNRQVCDDINECERNNGDCVPNSYCINTRGSHICGDCKHGFEGNQTVGCKQKNTCPNGERSPCHPKAKCI
IHRNNAYTCECIIGWAGDGYDCALDTDLDGYPDYALPCTDKHCRADNCVYIPNSGQENQDGDEMGDICDPDADNDGVPNG
PDNCPLVANPDQVNSQDDDPVGERCDNCPMTPNPKQIDTDADGKGDECDDDKDNDGILNIYDNCELVPNRMQDDTDGDGL
GDACDNCPMQYNPDQNNTDSDLLGDICDNNEDSDDDGIQDNLDNCPKIPNNPQLDSDGDGRGDACDDDDDSDGVYDIVDN
CRIIHNPDQADYNQDGIGDMCDSDFDRDGVDDQYDACPENPNIFTTDLRTYQTVVLDPEGEAQVDPKWIVFDEGRQIMQT
INSDPGLAISYQAFDGVDFEGTFFVNTRTDDDFAGFVFGYQDSASFYVLMWKQGPQTYWEASPFRAVGEPGFQLKVIKSD
TGPGEMMRNALWHTGDTPGQSRLLWKDPNNHGWKDHVAYRWRVVHRPSIGLIRVKLYEADSLVADSGFLRDTTMRGGRIG
LFCFSQEDIIWARITYKCNDDIPEGVTF
>NP_999631.1 3 alpha procollagen precursor [Strongylocentrotus purpuratus | PB0147
MKYREVLERHVFVCLSLLIIVFAYWADAAACVGCLSATCICNGTKGERGDRGYVGFPGPPGPGGFPGVEGPPGYKGQKGN
LGIAGSGGPKGFRGSLGNPGIPGIPGIPGEPGQEGPPGEPGIPGCNGTKGERGPSGPTGFGQPGSPGPRGDPGPQGPPGD
TTYGLKGIKGEPGRLGRDGYPGTPGDSGPTGPKGISGDPGLLGSKGTRGLKGEPGQPGVQYQGGKGEKGSVGTQGLPGES
CRDQAATGNDTTIVQGRPGPKGDQGEYGDKGDKGFLGMKGMKGPKGQYGLKGEKGLSGPQGPRGKIGKDGTPGNQGMKGS
PGIPGNPGPTGFNGQLGDKGDRGPKGRVGPPGPPGPSVPVNDKGTKGLPGPSGRHGSAGPRGYPGEKGRTGYDGKAGQPG
PPGSAGDRGVPGPVGIGEKGEPGNPGIPGMPGPNGFQGLPGRDGPKGDKGMAGLTIQGLPGMDGRPGPDGPAGLPGQVGD
AGPQGLIGEPGNGLPGDPGPKGQTGRDGPRGIPGDVGSSGQPGLPGPQGSKGEACAACRSGEIGPKGDPGQSGEIGQPGQ
PVYNGNSGPSGPKGDRGLRGLTGRDGQDGPQGPPGSTGRPGNKGQLGLQGEVGFTEPGPRGIQGDPGLKGDNGLNGEPGP
PCEPGAVKVNGEKGALGPPGPPGRDGVPGYQGQKGDRGLPGDSLRGSNGEKGDQGPRGERGTYGSPGDKGEVVYYETGTQ
GPKGEPGNPGTAGPPGPAGPTGNQGLPGDQGPDGYQGEKGSQGQSGPPGNSIPGSPGEKGAQGIPGDVGQPGQPGPTGPL
GNPGIPGAFGEKGDFGPQGNPGGQGLRGLTGQPGQPGIGGERGNIGDPGTRGRDGIPGQAGGKGETGPGGLPGGPGIKGE
PGLSIPGQDGSSGTPGRDGAPGGPGEPGPSGPRGEPAQPLLEETRITRLNGQRRPPGQPGDNGAPGNDGEPGPAGQIGVK
GSPGPLGPGGSQGPPGSPGPIGAPGEKGERGGMGTPGSPGPSGSPGAKGEPGLPGPLGEKESRGPGGVPGSKGESGIPGR
SGGIGSPGSIGLPGLNGVKGEPGIPGNSGIPGGRGLNGEPGPAGFKGFQGLLGVKGDFGIKGQMGFPGPKGDNAQMGIPG
QNGGEGFPGRSGIPGPQGAPGSPGEPGTDGSNGGPGSKGEKGQPGIIRDLLAGWRKGVKGDPGRTGPEGAKGNPGLPGIP
GESGDAGLPGSEGRPGQPGTSGPPGPPGPNGEPGLIGRTGTPGDPGPRGERGSYGTPGEDGIPGVKGDSGDPGLMGLPGG
PGLPGPGGPPGESGFPGVRGVKGIPGTPGLSALGIKGEPGFPGLKGDSGQPGLNGGSGSIGLPGMKGTKGETGPVGPRSP
LPPVIPGPKGEIGIPGANGDRGDKGDRGEPGRPGFQGRPGESGSPGLNGQMGDPGGPGFQGLKGSKGEPGPIPNVFEMKG
VKGDRGGPGPDGPQGPPGRDGRPGPQGPPGLTGDKGTPGVQGNPGVSGVPGEPGLKGEQGFRGQNGQPGDPGFPGTKGEA
GIPGSSSGFFITRHSQTTSIPQCPQGTAKMWHGYSLLFVQGNERGHGQDLGKPGSCLKRFSTMPFLFCNINNVCHVASRN
DYSYWLSTTEPMPMNMAPIRGGQLQPFISRCVVCEAPAQVLTVHSQTVNIPDCPDRWGVLWIGYSFMMHTGPGGEGSGQM
LSSPGSCLEDFRSSPFIECHGDGKCNYYATTYTFWLSSITGNAQFTMPQSETLKAGSLRTRVSRCAVCLRNQ
>XP_030845376.1 insulin-like growth factor-binding protein complex acid labile subunit [Strongylocentrotus purpuratus | PB0148
MLIGSQKPKRRRQKDVRLGHRPRSLRGSLSMRRPRTYIIPDPTPVRRRNIRSVPQGALSGLREIIQIDLHGNKIMELSPT
TFQGLSNLVVLNLNENRIKSLHTDLLHDAHALRTFLVSGNFLRSLPESIFRNNRQIERLDLSDNILWSIAEDCFQPLDAL
KFLNLSYNRVNEKNQMIFTGLSQLTELYLQRNKFTRIDPTLFLSNTQLKKIDLSFNRIKTIAPNAFQNQRLLEFLDLSGN
SLTSLNSLAFQGANALRTLDLSSNSVNEIMDDVFTNLANLTKLNLKGNMLPNITADTFGDIPSLSYLTLTDNNISRISSN
SLAGLVGLEFLDLSGNSLRHLQAGALQGLAALMELNLADNKLYIVEPEALKTTQFSFMSQLTWLNLQGNQLIELQRGVFR
GAPSLRVLTLSRNKILRIVPDAFSGFNRLHRLMMSDNNLRRLPDGIFRLLRTLEMLDLRNNSLTEISDKAFQGLTALSNL
NLAENKLTNDKMKWLKNIRPVQTLNLNNNQFSQMSSGDFEVAGNLRYLYLSNNNLTKVSVRNDSRLYLYNLTLSNNRLTE
LMDFSPHILPGRVLDLAGNPWNCNCRFVRFFTDMTRRNGIRLDKEYQTRCKTPRPLDGVKIMDLIRSDVPCRGDDLVDVP
AIADATSPSPTSVHAPSIPNYMALDRLRWSWVVLIWDSATDTPICNGALVSPSFVLTSYQCLARITKIESYLHLVSRCSR
PLDGDCPDKVWTAPSNLEIKVSAGQGTLPKFNVVAETYRVLRIHRVLPDATPDGPAPVLLQISPSVDLQGPASVIDILEE
TPTFGNLDGKRVLASGWWIDRSKAPDVVGRQKRRHYRLTSLQCGSPNEVHQPYLCGHLEQDLEDYKGWDSLGAPVTIRER
NQWKIVGILVKNEDGVGFIKDVRQDRDKINQIIAERSPLEHVTHPY
>XP_793866.1 retinol dehydrogenase 12 [Strongylocentrotus purpuratus | PB0149
MISLSTLSLERVPDFGQRGPGDLEWTTIALMMVVLVVGLYYYVVKVADRCSCPKRLDGKTVIVTGANTGIGKETARDLAR
RGARVILACRDAVRGREAEKDIRMSTGNDDVIFMKLNLASFDSIRHFAQEFNNTEERLDILVNNAGVINDGSLRTEEGHE
LVFGVNHLGHFLLTNILLDKLQKCAPSRVINVSSDAYMFGKLDLERLSVNDGRVKSYARSKLANVLFTRQLADKMAGTGV
VSFSLHPGSVNTEIKRNWAGWLRALAPLISFFFLKSVKAGAQTSIHCAVSDDILDQSGEFFKGCQVQKLSRTAQDQDLAQ
RLWDVSLEMTGLQSS
>XP_030844169.1 spondin-1 [Strongylocentrotus purpuratus | PB0150
MGAKKLFLGTFLLFVTIWIVSGQEEESCDPVMVPNIPKRNGDNGYRIRVDRLPTDYVPGQEYRELKFIFKRYPMCACIQW
KKRRFIGLPLLLDWMAASCVLKIYFFLSSLITVLLQSTTPVSFREFFLVATKGSAPNEAAGDFVITDRLKVRFSRTCSRA
LTHTFSSSKTSISAQWLAPPAGAGCVNFRAGVIQKKTVWFAEDGDLTLQLCERESAGNGPAPPPTLDPHACCAPPHEEAK
YRFTFVSTWTPQTHPRQYPTGNGNHWSDLIGASHGSDYTIWEYGQYASYGIKMVAEWGSPYRLEREIKEEGDNVKTVIFS
RGLFPAYGPRLRNMTSYFKTDSQRNLVSAVSMMGPSPDWCVGISKENLCTADCGWVERKVFYLQPWDAGTDSGIMYNSSN
SPLDPPDPIRPITSSDPDNPRASFYNPNGGPIGSLATVVIERVSIRNRSNTETEHGTGSQGGVHGGMPPKKPMMGGNPTM
PPKVMGQPDPTMPPKVMGGHDPTMPPKVMGGHDLTMPPKVMGRPDPTMPPKVMRGRDPTMPSKVMAQEPTMPPKQMGVIT
MPPKTIEIIPEGDIQTMPPKRRGKVVDCMMTAWGEWSECSKSCGKGKMLRQRMIKQRPRNGGEECGQTKERQSCNVARCT
SVDRDCRMSEWGPWSDCSVSCGGEMGIEFRMRDVARRARGDGAPCDPLKEMRACSANPC
>XP_030853890.1 collagen alpha-1(V) chain isoform X2 [Strongylocentrotus purpuratus | PB0151
MSILGDGGWHRVALRVSGNQVSLTINCLTPQKWTIERSIRPFPLDQGVFLLFGSNINGKANFDGLIQQALIIPDPAAANL
QCTDYDVDCAGAANVFLEEARLPDLNTGEQVNGPVNVYDGSGYGEGSDGFSYDISVIDPGLKVVVAGEGAGPISASGDNR
GSKGQKGNQGESRIEHYAGPVGPAGPRGYAGPPGPDGPSGGPGVKGERGRPGRDGVDGVNGLRGPPGPSFIVPAAVMSAM
SDAASSSKGPGSQANLAAIRQVLEEQRIAMRGERGPPGTQGSNGPLGPPGPDGPKGDPGSLGDFGPRGPSGTPGQPGRSG
KRGRPGKDGGRGPAGIGGEKGDRGYDGLPGLPGVKGTFGRSGDTGPQGDSGPKGRNGEEGPYGDPGPSGPPGIRGAPGSR
GPAGPQGISGLEGEPGGPGPKGPVGLPGVAGGPGPMGKHGPVGAMGPQGQSGPPGVQGPVGKPGIPGVPGTDGPAGHPGQ
DGQSGAKGSMGAPGSIGVSGYTGPMGVKGARGIFGNSGQKGNSGMDGLPGFKGELGMKGERGQLGVPGPRGSEGIGGPKG
EQGMPGEAGPIGTYGDQGPPGPPGIPGYPGNVGEKGELGHSGKRGRSGRKGSRGPSGMRGPIGPGGPMGGPGSRGPQGIQ
GVPGEYGEQGERGPPGPVGDQGPPGQQGPRGFAGGKGPNGPPGQDGMPGFPGSRGESGMDGESGTPGPAGVIGPQGPPGE
PGSSGPTGFPGPPGSPGEAGLPGNDGLTGPQGVSGPVGPPGIQGPEGARGFSGERGLRGEQGIEGMKGEDGPPGQSGPPG
VQGQLGPPGPPGGVGLPGRPGDQGPIGPSGERGDAGEEGSMGPAGRDGMPGPRGPPGPIGQPGPQGPEGERGDSGPIGIK
GTKGERGEGGPPGPPGERGPLGESGPPGDDGEQGIPGQSGPRGPKGEEGSGGNPGAPGPIGLQGMPGPSGSKGETGDPGL
TGAPGPQGNPGKRGSTGSQGIQGQPGPRGDNGAGGLKGDKGDPGPNGRTGRDGPRGFKGDSGVKGEPGSTGLPGNPGPRG
IEGPSGPKGNQGPLGFPGELGLPGPEGVPGTIGEPGQSGSDGDPGPIGMQGISGDPGRPGPRGRPGTPGSQGPSGREGPK
GDPGEDGPPGLRGDPGPSGDNGPQGPQGPPGLRGLPGPEGNPGEPGPPGAPGAQGQVGIQGPTGAQGDPGPLGPKGDRGF
LGRTGEVGIMGEKGDKGSQGEGGPQGPKGDPGSEGPRGVMGPEGPPGLPGRDGLSGAKGERGDFGVVGDRGAPGSPGQPG
PPATAEYLQAMLDRGMLTLRPDMYPNFGAGFGGGGAGASTDGEQTFEATGSDVPLSTSSSNPFGGTKRRKRQVGPSDLPS
DGDFLGIDELLGNGMQGIDDLPDMPFRYVPGFDELPLPYVKAMEVLFSSLDQLQTDVEGIKKPNGTKDNPARTCKDLLMC
HPKTQDGYYWIDPNEGCPDDAFYAFCNMTAGGDTCLAPDNTTGHTETKGYRKAVPGEWFLENLRGKEFSYQGGIVQLTFL
RLLSSKATQKFTYSCVNGVAWYDEAEDSFDNAIRLLASNDEEFTFDGLNQPKVIKDECKNKPSLGETILEVNTSKLHQLP
ISDFAPLDFGRRNQKFGYTVGSACFN
>XP_030842937.1 basement membrane-specific heparan sulfate proteoglycan core protein isoform X1 [Strongylocentrotus purpuratus | PB0152
MDTLPSSGDAEAKASTGAPPPPNSNQADTQGSSGGGNLPPETLNDGVGGITSANPNSITSPRLVYTQVTPTDDEDLVEGS
GTDGSGLPPVSVAYYRSGFLLTNVQFVSELQYRNSTDFQTVSENVRIAVEDLYADLPGDQFVTILQFLNRTGNTMIQFDL
GSAGFYSESALYRVLDTAVRSSQVGRYSVDPNELDFAPLPVVLGTTTPFVETQTPIPTFVPQCDVAREFFCTYYGTCMSL
NLRCDGVLHCPSPSEEADCQPRCRYDQQTCPDGSCLDAYQICDGYNDCSDGSDELGCFLCDLGQFECDGGTKCILDLLVC
DGLYDCTDQTDELFCPPRESTEAPPRPDPTTPAPPTTTTRAAPRTPIPTTPVRPSTQCSANEAYCRSGRIRCVPRDFLCD
GQNDCEDGSDEYGCQQRKCEPNEFQCANLLCAQKIWRCDGDDDCGDGSDERDCPTAAPGSPCRHSEFQCLSVDECVPRGF
QCDGETDCVDRSDEIGCAEPTVIRSPVEIIQVQIGERVEIICEAQGIPTPIISWRLNWGPVPDRAIITNSNGYGTLVLEN
VRESDQGAYTCEAMNNQGYILAQPDAILTVISGPSICTGSYFNDDAQIVSECIACYCFGASTTCYSSTYNRFETSLYFGE
IGNLKGVRLADLSSPSASLGVLEDTYLEVNPTEREVVVRDYNRRLPTSTYYWVLPEDFTGNLLTSYGGNLRYQVNFIHIA
STAQVADVYIKGNGKTLSYQISDEPASGIPTQRQVPLTEAGWKNVVTVGGGGRGDVGSELLIDATREDIMLALQNVDSIL
IKATYSYNQYQTSLADVVLDTAVPEDTGRGRAVLVEECRCPIGYEGLSCERCSSGYYRAPGQDASSLGTCQPCQCSGLSN
SCDQVTGQCLCTGNTEGPNCERCAEGFFGDPPNGVPCLTCPCPLTFGPNQFSPTCILDTDGRVTCDACPQGYAGRQCETC
SANYMGNPTVEGDSCVPDSLGDCNVDGSLAWTGSNCLCKDNTDGVLCDQCRSGTFNLAPDHQYGCIRCFCMGITTDCDST
VQYRSQVNAEFSRDGQGLTLNNRDFTENVTSQDLTVNYRQRELVYGGFNNLPADVYFWVLPYRFLGDRVSSYGGYLRYTI
VIDGVDQQGASSQRVPDVEISGNGITLVYNRDRQGTIVSSRTETPFRVPFLEQYWTRVDFEPANRENLMMALADLDYIII
RATYNSFTTVSGIRDISMDIAEARNTGQGRAFAVEQCTCPYGYRGLSCEDCDVGFTRSGSGIYLGFCSRCECNGRSTDCH
PETGECRNCQDNTMGRFCDQCAPGYYGNPTQGGRCLPCTCPLAIPSNQFSPTCFLDYDNDLTCDSCPEGYTGRRCESCAQ
GYIGDPAREGDYCRPEGGCQCDGRGTRSSQCFNGRCDCKDNVGGDSCNFCQPGFFNLASSNQEGCTRCFCSGLSVPCSSS
SYYRQQLRVTLQSPSDPRDVALVNRAQTQRITTGFGINVPSNSIAFSQFNQLPGDVYYWELPPKYRGNQITAYGGYLRYT
VSYSTSQARGNPISDNDVEITGNDIVLVYRQPTNLEPDEARPVVFQIVEDNFVRPDGNPATREHLLMALADLSNILIRAS
YHSDMQESSIRNVALDIAISQNTGQNVALEVERCDCPQGYNGLSCEDCAPGFTRSGGGLYLGTCVPCECNGHSNQCDPET
GVCYNCVHNTFGPYCDQCGAGFYGDATSGTPGDCRQCACPLSIPSNQFSPTCILDTDGRLTCTACQQGYTGRRCERCASG
YEGNPTQPGLSCNPASTGDRIPSVIASPTEASSVLGGTIVFQVRITGNYTSAQWRRADGQPLSPSAYVEPGTYRLQIRNL
RANDAGIFIFTASNRYGSGTAEVRLEVVGQAMRVVINDPQTVEVPEGETVQFVCRGISQTPAYTIAWSRSDGTLPTNARD
FMGILTIDTVRLSDAGQYVCMGSNQRDTADAYATLIVTSSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSGG
QGGVLNSESTFENGLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVTISPASESVSEGERVIFYCQATGD
PAPERTWSRIDGDMPSSAREENGYLVISAVTYEVEGVYRCTATNSHGSDYSDAQITISTDSRRSPTARIDPAEITVTQGA
TQVLRCLTTGVPTPTITWTRGSGPLSANQQALNGVLRIINADVTDRDMYSCTATNIAGSSTATAYVEIERRESPVIEILP
YSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPLSSNTNDEMGVLTIMGVTAENQGAYICTGTNSAGSATATATIRV
QGLPQISITPTNPAEFRVGETAVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYMCR
AENGAGYVEQELLLRVTDTSVPHPPSCEVSPRELEVIEGETAVFSCTSPGTPAGYTITWRRVSQRMPSTVSISNGLLTIP
QARSQYAGQYYCIVGNEHGYQQDLVTLYVLVLPSLSISPTTQTVTAGEIIRISCFAEGTQPITCEWSKYGGSLPPTAIQS
GGILQISPATATDAGQYRCVCSNTAGFRDSYMTVRVQVIPTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDGVL
PAQHRITNGVLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIRVGETTTFECLSTGDPTPVV
TWTKVNSEMPISVVLQGARLTIPQVSLSDVGFYRCTATNIVGSRTSQVFLYVQAAPQLTVVPSTRTAPVGATLEFSCLAG
GFPTPEITWHKEDGDLPDNYQIDNGLLTITNVKEADEGTYVCIATNQGGSTEHRARLVVGELIPYFVQMPQSYIGYPRLT
NAYREFEIQVSIKPESPEGLILYNGQSVDGTGDFFSFGLHRGYAEFRYELGAGTTLIRSDRPLELGQWHTVGIRRNMTRG
YLQVDDLPEVEGRAQGNFQGLDLVQDLYLGGVPNFDEIPSTAGFTTGFIGCVSQLIVDRRELVLDSARTRVGVEQCPTCE
VNPCANGGVCEEARAEQGYRCRCPFGFTGTNCEEVANYRCVPGICGEGQCVESSGLSGYICHCPVGRTGTRCELGVPIED
PSFLGDSYLSYPGLTSNHRQVQIAMMFKARSIEDSLLLFNGQGLRGKGDYISLFMKDGKLVFQYDSGSGAAIIESTKTME
AERWYTIVAERNLQDGSLQVDDTEAVKGRSPGSSRGLNLRLPLYLGGIDKFEEVPQRLGVTKGFDGCITEVEIDGEPLDL
VEGASASNNIEDCGENLLCQKGECLNGATCTPTPDNLEYSCTCAPGFTGRHCESEVGSCNVEQPCKNGGRCEPVDGGYIC
LCTLGFSGNMCENVERFSYSVALGQASYLKLPKTVIPRGRGSSAITEIFSFSIATDSTDGLLLWQGVPEGSAGERQDFIA
VGLQDGYIVFSYQLGSGEANIASTVRIDDGVEHNITITRQGRDGTLLVDEDDVVTGQSAGVLRMLNVKGALFLGTPPDIE
ILTGTKYSKGVEACIQDLEIQIDENPSAVINLYQEAIDGINVENCEF
>NP_999631.1 3 alpha procollagen precursor [Strongylocentrotus purpuratus | PB0153
MKYREVLERHVFVCLSLLIIVFAYWADAAACVGCLSATCICNGTKGERGDRGYVGFPGPPGPGGFPGVEGPPGYKGQKGN
LGIAGSGGPKGFRGSLGNPGIPGIPGIPGEPGQEGPPGEPGIPGCNGTKGERGPSGPTGFGQPGSPGPRGDPGPQGPPGD
TTYGLKGIKGEPGRLGRDGYPGTPGDSGPTGPKGISGDPGLLGSKGTRGLKGEPGQPGVQYQGGKGEKGSVGTQGLPGES
CRDQAATGNDTTIVQGRPGPKGDQGEYGDKGDKGFLGMKGMKGPKGQYGLKGEKGLSGPQGPRGKIGKDGTPGNQGMKGS
PGIPGNPGPTGFNGQLGDKGDRGPKGRVGPPGPPGPSVPVNDKGTKGLPGPSGRHGSAGPRGYPGEKGRTGYDGKAGQPG
PPGSAGDRGVPGPVGIGEKGEPGNPGIPGMPGPNGFQGLPGRDGPKGDKGMAGLTIQGLPGMDGRPGPDGPAGLPGQVGD
AGPQGLIGEPGNGLPGDPGPKGQTGRDGPRGIPGDVGSSGQPGLPGPQGSKGEACAACRSGEIGPKGDPGQSGEIGQPGQ
PVYNGNSGPSGPKGDRGLRGLTGRDGQDGPQGPPGSTGRPGNKGQLGLQGEVGFTEPGPRGIQGDPGLKGDNGLNGEPGP
PCEPGAVKVNGEKGALGPPGPPGRDGVPGYQGQKGDRGLPGDSLRGSNGEKGDQGPRGERGTYGSPGDKGEVVYYETGTQ
GPKGEPGNPGTAGPPGPAGPTGNQGLPGDQGPDGYQGEKGSQGQSGPPGNSIPGSPGEKGAQGIPGDVGQPGQPGPTGPL
GNPGIPGAFGEKGDFGPQGNPGGQGLRGLTGQPGQPGIGGERGNIGDPGTRGRDGIPGQAGGKGETGPGGLPGGPGIKGE
PGLSIPGQDGSSGTPGRDGAPGGPGEPGPSGPRGEPAQPLLEETRITRLNGQRRPPGQPGDNGAPGNDGEPGPAGQIGVK
GSPGPLGPGGSQGPPGSPGPIGAPGEKGERGGMGTPGSPGPSGSPGAKGEPGLPGPLGEKESRGPGGVPGSKGESGIPGR
SGGIGSPGSIGLPGLNGVKGEPGIPGNSGIPGGRGLNGEPGPAGFKGFQGLLGVKGDFGIKGQMGFPGPKGDNAQMGIPG
QNGGEGFPGRSGIPGPQGAPGSPGEPGTDGSNGGPGSKGEKGQPGIIRDLLAGWRKGVKGDPGRTGPEGAKGNPGLPGIP
GESGDAGLPGSEGRPGQPGTSGPPGPPGPNGEPGLIGRTGTPGDPGPRGERGSYGTPGEDGIPGVKGDSGDPGLMGLPGG
PGLPGPGGPPGESGFPGVRGVKGIPGTPGLSALGIKGEPGFPGLKGDSGQPGLNGGSGSIGLPGMKGTKGETGPVGPRSP
LPPVIPGPKGEIGIPGANGDRGDKGDRGEPGRPGFQGRPGESGSPGLNGQMGDPGGPGFQGLKGSKGEPGPIPNVFEMKG
VKGDRGGPGPDGPQGPPGRDGRPGPQGPPGLTGDKGTPGVQGNPGVSGVPGEPGLKGEQGFRGQNGQPGDPGFPGTKGEA
GIPGSSSGFFITRHSQTTSIPQCPQGTAKMWHGYSLLFVQGNERGHGQDLGKPGSCLKRFSTMPFLFCNINNVCHVASRN
DYSYWLSTTEPMPMNMAPIRGGQLQPFISRCVVCEAPAQVLTVHSQTVNIPDCPDRWGVLWIGYSFMMHTGPGGEGSGQM
LSSPGSCLEDFRSSPFIECHGDGKCNYYATTYTFWLSSITGNAQFTMPQSETLKAGSLRTRVSRCAVCLRNQ
>XP_030830261.1 leucine-rich repeat-containing protein 15-like [Strongylocentrotus purpuratus | PB0155
MVELSQQALLVKLVVLSVCFITDCMAVSTGCSDVCEYNAWGKEAGCQGRDLTYVPQECKSAKTLQMQDNRLQHLTEGSFS
NFSNLKYLYLDRNNLTLENGAFEGCTELQQIHLNEIGIPTLKPDMMRGLPNVLHMFINKAGLEVIQPGAFQNMTNLQYLS
LQENELMTAPCDAFSTVNSLHTLFLDSNKITYLPDDCFSRFSHLTKLYLKNNPLGDLSGRAFSGLGNLVHLDLQYTDLTR
VPTGIFPYANKIETLQLSFNDIQHLHNRDFASLSGLRKLYLQHNQIISIQSDSFEFLGSLNVLDISFNVIKSIETEALDN
FPHLTKLRLQYNSLNSTRNITFSNIPQVAHLNISHNPLHCDCSIYPLQYWLDGATAMTSDAGSSYLASCSTPESLNGQFL
TKLSHHDICPSVKPVPLVTDLITPAALLKKKDAPTSTGSLDSKMIGIITGVAVLIIFIIGGIIILVMKIRHDRDEIDIGD
QYERGGQLGVKPPAHGPPAPAGAMYITENLLEKGPELPPRRTDVFPNGSRCPGSSVTSGTQLLQCPYPSIGDVDGPEGTM
GSVGYISPLANGERTRPSLSPQSSLSTSSPEEYGEYSVVFPEEQPSVENEEAPSAAEWLNKNFNPSPGADTTMESKSKGQ
TPAAESKNGTGYILWRPS
>XP_030833101.1 fibrillin-2 isoform X1 [Strongylocentrotus purpuratus | PB0156
MMRSSLLVLLACLSTVVVAQSNVINGPNVCGMRFYSYCCPGWRLHPRTKQCVVPVCNRPCGSGYCQRPNSCSCPGGQISV
SGCDGYSGGNPCTTQCLNGGSCQGNSCNCPNGFSGTNCGMPTCNPPCQNGGECSGGNRCSCPPGFGGSQCQTDYRTGVCY
LQSTSNGYCSAGVEGLHCTKALCCATIGQGWGDPCENCDTFDNPCDRGYILNGRTGQCIDADECLMIPGLCDGGQCTNTQ
GSYACQCPAGFELSMSTLSCVDMNECQTGYLCQNGRCINTQGSFRCDCNPGYFLGQDGHHCTDIDTPNTPVTPEEIGYCY
MRFRNRNSRGTSCSQELAVRMSFLDCCCSVDHAEGWGLSRSDCSPCRTENEELYRRLCEGVGELTTPQPRRTPNPQTRTD
GPGVVTLTPPTVTPPRKITPRPEGICLMVPNICRNGLCVSLGGVMEYRCECFEGYENAGRYTCQDINECRDRSLCRYGAC
ENTDGSFRCVCPSGYKLSLDQRSCEDVDECRTNPNVCHHGTCMNIVGSHTCDCFEGYQKSIDGRYCIDVDECTLGSHRCR
NAECENLPGTYECICTEGYEAIGSSGVCIDVNECAQETNPCPLGFCINTLGGYQCQCPVGYATGQDGTCVENRRGFCFLD
GDLGRCTHQSMGQMTISSCCCSAVLLQEALSWGPNCESCPPQGTLQFEQLCKHGTGWTSQRININECTLFNNLCDNGVCE
DLTGNYKCRCNSGFQPQADGKECIDENECSYNRLLCHNGACRNTPGSFVCECPDGYELDARSSVCQDVNECQNPSLCNNG
RCINTRGSYRCECIYPGTELDPTGTICVDNRIATCWTRISNGQCEADIMGPMRRDECCSTFGRAWGSPCEACPLAFGDCP
RGFSEINSECVDLNECELNPMVCNNGLCENTMGSYRCVCEEGLTLDTSGRNCVDLRSYECFLDYSEGQCSSPIPGLYRNS
VCCCSLGYSYGDQGRCYECPQEGSVEFDVLCPRGRGFADTRPRPDLLDGTVYINDINECNAYDGICKYGECTNIIGSYDC
VCDVGFAMDEFGYQCVDIDECRITFGACGNGSCENTPGDFRCNCYEGFEAHPVMRSCMDINECETVPGLCRGGSCTNLPG
MFRCDCPLGQELTPDGQACRDINECSISTGICSNGECHNIVGTYRCMCNPGFRPTANYRACEDMNECDMDNGGCDHNCVN
SQGSYECQCQSGYSLRVNGRTCVDIDECADNPDICGGGQCENQEGGYLCDCFVGFRPADDFRSCLDIDECSTDAGVCVAG
VCKNTRGSFTCQCFEGYSMKPGIPGCSDIDECMLQMHQCAINSQCENTIGSFQCRCNPGFIVDENANICIDVDECESSNH
DCHEDARCVNIPGSYQCQCNQGFIGDGLSCIDVDECMQNQALCVNGQCINNPGGYVCECEMGFYPTERRDSCEDIDECSN
FPDICVFGQCINVPGTFRCECNPGYMLDIGGGNCTDVNECEDPGTYCVSGLCTNSMGSYVCECPPNWVLSRDGTTCADVR
TGLCYAHGPGAESRLDVNECSLLLGTSIPRTKCCCSELGKGWGDPCELCPLVNTTEFFLLCPYGIGVHIDPNATRPVNEI
NQCRDFPNICRGGECQQVEGSFRCVCPTGYEYDFEQMMCIDIDECQLSAYICGAGTCMNMEGSYTCMCPMGFMFMNMPTG
KNCMDIRELTCYMSYNQSAFPLPECGSPLMTSLTKKVCCCSALMASAWGTRQECSPCPAHMTEDYYRMCGATSPGFVVNP
ETGLPEDVDECRLIDGICANGICVNTPGSFRCDCQPGYRANMATHICEDIDECFEGMHRCVGNSICRNTPGNHECICPPG
YQLSVSRLSCDDINECLTRPGTCINGQCTNQIGSFVCVCDQGFQLSADGTQCNDIDECFRFPDRCGNGTCQNVVGDFACS
CNRGFELTINGDCADINECATMQGTCPNGRCVNTPGSFFCDCVEGYVLSLSGLRCEDENECISRLNICQNGRCDNTIGSF
RCSCFDGFQLSPSGQECIDTDECVIIPDMCRNGVCQNTQGSFQCTCPPGYLLSSDGLICIDMRRSYCYNDFVGGQCTDAR
AGNATRKECCCSLGAGWSSPCNLCPRPSDASFTELCPDGPGYAPSLTPDLYEDINECKVFPGICENGICINTDGSYRCQC
QPGFILDTTGRICVDRNECQENYNVCGFNSTCYNTLGSFECNCGEGYQVGRRGTCEDINECRRRRGQCAFRCQNLPGSFR
CLCPNGYTLTDDGRHCRDLDECDTNLNTCRYRCKNLIGKFMCQCDEGYTPIGGDGNNCRDINECITNHGVCQNGRCRNTE
GGHTCICNQGFTLGPSGKDCIDRRTGFCYAYVPPSGCESSQGGMQPVTMESCCCSGGRAWGSTCQICPVYGTIEYNRLCT
ATTPVDPCQIVQGLCENGHCLGGSGGYLCQCNPGYILSPDGTRCEDENECNRAPPPCSYQCKNTPGSFRCGCPQGYLLSE
DGLTCREKDECSMGIHECQFECRNTLGGFRCVCPEGYIQHGSTCIDVNECIQTPDICGAYGTCQNTQGGHRCECQRNFRP
DPSTNTCVDINECEDQPDICQYGCQNTIGGYRCVCPDGFEENFYGRCIDNNECRQSGKCGQATCYNTQGSYQCGCNNGYA
FDQQNLACNDVNECQGSYGNTNSPCQYSCDNTDGSFSCGCPPGYTSVVQGACVTDRDSVQPCYSCNRQPRQRRSATETND
KESTLISNNTAILYHIPLSKAVPKQQIAKFKTGYTRIVARYEYVILSGNEDNIFMMKKKSDGMSLLRFSKHVKATGLYEL
EIEGVLKRKNDTILAEVQTVVEEPVAMQIQVQIVADEEE
>XP_030853901.1 complement factor B [Strongylocentrotus purpuratus | PB0159
MKFLAIIVAAILGILCSSAEGTSCRRPRSLRKGRYEYQNSTDYGLTHLPVNYIVRAECEPNATLVGDEFIICQDNGKWSD
YPYCHAPLVCFRPPESPVNGYVRMRGKSARSIAVYRCNPGFELHGQRTVVCNETTGSWQGDAPRCFRPLSCPNPNEPSGM
LALVLDENSGIKRGDLYTERTVFNYTCQTGYHPTGDVTITCQNGTWEADADVPECNRIICAPPILEPIENGTHNIENRTY
HVGEMVQYECNEGYLVDGISWQVCQSHGGPNGIWSDNVPTCKVARCPHPGSRHLDNDEISFSPRNGQGATNSWPVGTVMT
LRCRSHLELLGSSERVCQPDGHWNGTLTSCHSEEYYCPALGNPIHGSKVAIPQYRVNTYVRFRCNGGYEMVGSEERMCTF
SGEWTGEMPRCMSRDEFDEFARVTSGLGKAFDEMAIDGGFGVGFNNTTSNSGSRRRKRTIDLSNSSALDIYFAFDASNSV
GLENFEKGKRFAKLLVNKLDENISAGGTRVGALYYSSQSMRAFNVNEYRSTDGVTSAIDTLIHYKSDGTNLPAALINIKE
MVAETLGDTPDNTRRVLFIITDGFSNVGGAPSEHALTLKEDLGFKIHCIGISQKTDKKALAEIASRPIIEHVFYLSDYIE
LDEAVDIITNTKRSYEECGKSGNTIVARSRIVGGVDAKSGAWPWQAALYDTATNDLLCGGSLIRKNWVLTAAHCFRGLFS
LTRDTTTVYLGLTDRSGDLPRSQQFDIAQLIFHPQYFVEGSAQHNDVALLRLDREAELNPYVRTVCLPPSSVTDPLKANW
YLKPDRVAKVTGWGHSDIRLPDEPVDPATKNLQEVDVPLVSATECRRVMQDNNQIPVDTTTELCAGADQRDACNLDSGGP
LVVSRNGIYRQVGIVSYGLGCGLQNTYGVYARLPHFVEWVEKTIQENQ
>XP_030855505.1 transforming growth factor beta-2 proprotein-like [Strongylocentrotus purpuratus | PB0160
MFSSSSTSSSIRCCLAASWLGLAVLSLTFDGLGAGGQCKFDLQEYQDRRIAAIKGQILSKLGLTALPTDDGPEDVPKDIL
DLFNQTVTLLEEKYENEREQCKGLSGGSDDYFAQLPILYGIVETDIEKDIGNYATVKRLSKFFRFDLTSFEEDSQGDEVT
EAEFRLYQVPNEMKDTEQQIDLFQLITSYNSTEEPTRRFLTSWTVSTTREGWLAHDVTDVVREWVADPETNLGFELNLNC
GDYLLGPTTTTPASIPKDQHKLHVLFADPRGTFPSMDNGRGDGNPRGEGFPSINHPRLVVMTPANHSRGSESNSVRKRRS
TSYSGSQCDQNSPNCCLRPLVINFRRDLKWNWIRQPRNYSPNFCAGSCPYILSADTSHASVLSLYKHLNPDASPSPCCSP
QTFKPLTILFYNRGRPEIRQLNNMIIETCRCS
>XP_030827867.1 filamin-B isoform X2 [Strongylocentrotus purpuratus | PB0161
MSTNEPTDDGGEQKYDLEDEEEMPLAERDLADDAPWKRIQQNTFTRWCNEHLKVAQKHISSLETDLGDGLRLIALIEVLS
QKRISKFNKRPTFRSMKLENVSIAIKFLEDQNIKIVSIDSTDIVDGKLKLILGLIWLLILHYSISMPMWDDDGDMSSDKK
KQSPKEKLLGWINGKVPDTPIHNFNKDWNNAKAIGALVDALAPGLCPDWEDWSPKDALKNATEAMKLAEDWLDVPQVLRP
EDMVNPAVDDLSMMTYLSAFPKAKLKPGAPLRPKSNAKKVRAYGPGLEDGNVISKPTEFTVETFGAGSGNVEVLIKDSKG
NKVENTMKANKDKKQTYTVEYTAKVHGKHTITITFKGVEIPKSPYTVNIGNITSDASKCSAKGPGLEASGVILNQKTYFE
IFTAGAGAGTPTVMLLGPDGKEVKATITDKGKGVYYVEYTATMVGTYKIEVKFAGAQIPGSVFNVKITHALNTSKAFAYG
RGLQPKGQRVKEECVFFVDTKEAGEAELKVQIIGPGGVDEPVKVTYNNDGLYTCKYSPYKPGRYIVNIKFGGQPIPKAPF
TVNIGPEPTGPITFVRAFGPGLEKGVVGKPCDFTVETNGAVGALGFAIEGPSQAEIKCKDNGDGSCEVSYFPTVEGEYAI
HVTYEEEDIPNSPFIAKVTPNPGGFDATKVKAFGPGLKPDGIEIKKKTEFTVDVKNAGKAELVIDIKDQWGNKVAYELKD
NKNGTYTVYYTPEHPLKHTVAITWGGVSIPESPFKVSVGGGVSKVKVFGPGVEHGMVKAKTPTHFTVDCKEAGKAPITVG
IKSKAGVNGPKEKEIPVQVKDNNDGTYAAQYTPELPGEYAVGVKYGGTEIPQSPISVSVVPDVEVGKIQITDLQESLDVG
KENSFHVDTSKAGDGELEAFLTGPDGQIVPVKVVPVESGFDVQFTPTEEGPHKLDMKYGGCPMLDKPIELEAIPKADASK
VLAEGDGLKKGFVGKPADFMIDIRNAGRGGLGVTIEGPSEAEINCEDNRDGTCSVNYTPDSAGVYNINILFDGKHIEDSP
FHAKVVDPSLVKASGPGLTNGAFMDFPCTFEVDCSEAGPYFDDEYDDKFALPVNCMAVGPDGDILKVDVKPLEEGIYEVT
YYPEEEGPATLNTIYCGQPIPNFPKEVQVQEPIDLEKIVLDGAGLENAVFLECPTDFKVDAKALDKPLNKDLFKTEVTTP
SGKKLKPTIKDNQDQTFTCAYTPVEQGTHKVDVAFAGQPLGKSPYTTEAVPGHDTSKVKAYGPGLQAGLTKKPAQFTVET
KNAGKGGLGILIEGPSEPKMTCKDNKDGTASVEYLPVEPGDYAVHVTFADEAIPGSPFRPSIQDSIDASKVKAHGPGLSK
DGVRANVPAKFTVDATKAGKAPLDVTVIQEKGGPEKAKIVDNKDGTYDVTYVPKTEGRCQVDIKYDNKNIPDSPFNTKVL
PKADASKVKVAGPGVQKTGVLASLPVEFTVDTREAGDAELIISITDKNGKPVKPDIKDNGDGTFTISYVPTDVGQYTVLV
TYGGKNVPASPFSVKTSPTGDASKCSILEETITKTVVVEEETVIKVNSRDAGKGRVTCTITGPNGQEIPDVKVIENPDGT
FDIIWTCPAAGNYEVDLRFGGVSLTGGPITIFAQPGPPEDLIQPESIQAVQSAPEQSLRPSNMPVDACRPLDLVIPVIGA
GLGCISGQVKTPSGRKEIPVIIENKDGTITVKYSPTETGRHELAIKYNGKDVPGSPFHFHVDELKSGNVTAYGTGLTHGI
SNEQCHFIINTKDAGAGGLALAIEGPSKAEIKCVDNKDGTCSVTYFPTKPGQYDIVVKFADKHIPGSPFSAQVVDKSGSR
MSIGTPSDVPLKITESDLSQLTGSIRTPSKHEEPCALKRLNNGNIGITFTPKEIGEHLVSVKKRGQHIPSSPFKIIVGAQ
EVGDASKVKVTGRGIKEAQAGQMAQFLVDTRNAGYGGLGVSIEGPSKADINCEDNGDGTCLVTFTPTEPGTYNVNVHYAD
QLVPGSPFQVAVQGDSTELPLIRETLVRPTKATPVSNVGSECELTVKIPGTDPLDMTAQVTNPAGRTVDAEIMDRPDCKY
CVKFVPAMEGVHTVSVKNKGLHVPGSPFMFTVGPFGEGGAHKVHAGGPGLERGEVKQPAEFTVWTREAGPGKLGITVSGP
AKAPINFVDNKDGSYLVSYVPTVPGEYVVDIKFNDKPIPDSPYKPFVVPPLGEARRCSVSSIQEHGIKINHPASFVIQLN
GAKGHLKAKCKSPSGAEIDCVITEIDEENYAVRFLPTENGIHSVEVFFKDSPIPGSPFRLRVGTVEEVGDPGHVHAYGEG
LERGKTGDKCEFIINTCGAGAGTLGIQIDGPSKVKLDVTEIGEGYKCVYVPTHPGEYMITIKYGGPTHITGSPFMAKITG
SAKGGKAGSVETAQVMVETIVKTTTTTGFQAPVFTSDASKVVSSGMGLKKSFLNKKSQFQVNCSDAGNNMLIVGIAGPKT
PCEEIHVKHTFGQRYTVTYLLKEKGNYVLIVKWGDEHIPGSPFSLQCA
>XP_030835556.1 uncharacterized protein LOC578177 isoform X1 [Strongylocentrotus purpuratus | PB0162
MGSLKFVCLCLGALMCVSTLMTHVDAKLKAKKIHAPSYASKVDLVQVTEEGRHRERRDDDDDDDEDIDSDIDPVIAELNR
LLAEIRTIQDGAQVDTQGQNRAASSHRHPVRLQGGTSEYDGRVEINYEDQWYMVCDDYWGIEEATVVCNQLGFNGALEAV
QRAADEYGFNDNGFAMDDVRCTGMEPGLSECDFPEWRSHNCDKGEEVAGVRCQPERTSPNRAIRSVQGAPTIPDSSQIML
RFNVNELPPWLQSILGSKPSETSTPGSATGGTVAGSSGATGSDGSSQVPVTRARDPECFTMSNGQDYRGVVRQTISGYAC
QRWNVQTPHGHSYTPAQYPGILGNHNHCRNPGTFSQPWCYTTNPRIIREYCDVGNPRTSCATTAQTVQGNGEATTYLSEY
ALVPAAYLGGNNDGTHSVATAELCAERCNKERSFVCRSFEYNEQSNECLTSSSNSRDVDLTFLLSTRFNYYERLDIGPIA
LFDITPNSAMPGNNIESLTAVSMEECAERCLVAAWPCASFDFARRANRCWLSNKSPSQVSIRSDFPDNPYDFFSRRGPAT
PNCYLGTGENYRGFSFTTTQGHQCTNWQAAAMDNVGVTPVLFPDGDIGNHNFCRNPDSDRRPWCYYKDSGSSTVSGWMYC
NISTCETSTAPPTSRPTARPPPPTQAPSGPIPVSRGKPAFQSSTHTSGGIMANAGLAVDGNPNPSFDQGSCSRTQSRANS
WWYIDLEAAYDVTTVVIVNKDVQGERLRGAMVTIGSSATDPSTRTQCGRITRTMTNAASRTPHQRIRIDCPSPIRGQYVH
IGSPRKDYLSFCEVEVYGRPSSPPTPAPEPTVSCTAAEFECASGSVSCVPERFQCNGQSDCTDGSDETGCPDPMDDFTII
ADKYLPNREPAVIYMEKTADECARFCVSAMTFVCRSFDYNSAERTCSLFNVSRSQNGRLFSRQGTAHYERISQTTDCTNA
NGIEYHPCPSGRCIPNEWLCDGDNDCGDFTDESNCGTLEEFEVRIVNGTAPNEGRVEVKYRGKWGLVCDDEWDLSDGHVV
CRQLGYTRGASDVYIVGEFGHGNLVDIFMDDVRCTGNEQSLADCPHPGWGVNNCVVGEAAGVLCKLNQDCPANHFECNNL
KCIPEGNVCNDMDNCNDGSDELNCQPELPVLPVRLVGGNGRTSGRVEVFHNNQWGTVCDDYFSEAAARVVCNQLGISGDV
QVYPQAIFGEGTTQIWLDDVTCAGTEPSLAQCTIPNGIGRHNCQHNEDVGVECGRETLPCGVRGIENGNIMARIIGGSSA
KRGNWPWQAQLILRGSGHYCGGTLIDETHVLTAAHCFQRYGKNSFKVRLGEHHQHINESSEQDFRISCIYKHPDYDSRTT
NNDIAVLRLDRPAHITSFVTPACLPTDGEFAADHQCWISGWGNTGNDNYPSRLQEARVPLLPRSTCTRQNVYGNKLTPQM
LCAGYLRGGIDSCDGDSGGPLVCENSNSVWKVVGVTSWGYGCAQPNAPGVYAVVTRYLGFINEKMITRTCT

>XP_030848953.1 leukocyte elastase inhibitor-like [Strongylocentrotus purpuratus | PB0165
MAFSKQQDTSGQLVQLSSANIGFALDLYQTLQDERRGTNLFFSPLSISTALAMTQLGARGDTATQIADVFRFNQVDQDQL
HGTFKELNNLLYQTDSGYKLHSANRLYGKSGYNFVQSFLEGTVFYYGAAIEAVNDFASPIATQSINDWVSKQTEGKIKNL
IAPGTLNDLTRLVLVNAIYFKANWKSKFYAENTTHDTCTFKVFDERYKVPVSLMSQKGRFALTVDNTNDCLVLELPYESH
NLSLLIALPTKDDGLGQLETKLSVDVLQSWDVGLKSRRVNVLLPKFKLEATFQLKEVLKRMGMPDAFDEDRANFKGISSE
EREFYISAVIHKAFINVNEEGSEAAAATAFVMAGGGPRIEREKPILFRADHPFLFMIRHRSTKSVLFMGRMMDPS

>NP_001091929.1 dickkopf-1 precursor [Strongylocentrotus purpuratus | PB0166
MAAPSAILKYLLSVLVCYVLFAVPSQGIYIKDRSSRQRGSERTRGRDNPGDDTSVEERRREPFTRTLVLCEADRECPYKY
YCHSGEGHKSCLRCRKSHRRCHRNKMCCQGNTCVDGRCIPHQFRFDEAYNTAVQNFESEVNEEEESILQDTKFKLRKARQ
GEQCSSSVSCEDGLCCAQHLWSKMCKPMLEEGDICTKKRDRLTDVFQRCECSQGLSCKRDSVPERRLHVCQAVKHRSSGT
STERGGGEGAAQGETLSQRERLLSLPVEKIRPLPSKNDGDLLGYLSAESGEKLFDLAGRGERWMMGRSAEKLKGTAYRDT
TEITRTEQADIEASQLTVL
>XP_030835262.1 carboxypeptidase D [Strongylocentrotus purpuratus | PB0167
MTLLLALLAVLPFFSSVLGEPITATSEFPGSDYQWEHHDQEALYQILRDTNEECPEITRIYSAGESVEEEDLWVIEISDN
PGKHEVGEPEFKYIGNMHGNEVVGREMLLLLIPYLCKNYETDPDIKWLVDNTRIHIMPTMNPDGYAAALEQLEERGENAW
STGRANAHEVDLNRNFPDLDRIIFGRRADRFPRRHGLNNHITSHVDPRQLEPETRAIMSWLQEYPFILSANLHGGDIVAN
YPYDSSHDGKANYEASPDDQVFRQVSLAYATPHPVMSDPNREQCDIGGEDAFKKGITNGADWYPLKGGMQDYNYLHTNCF
EITIELSCKKFPSNPNDYEEFWGDNKQSLLDYIRQAHSGIKGTVTDENGVGIDDAKIKVWELTGPASEEHYIDHDITTAD
DGDFWRLLVPGTYKVEAEACGFHAVNKTCTVAEPGTNVEASDCSFQLEEDNSTEGCSIEELESFLMNRLYPTY
>XP_030841772.1 slit homolog 1 protein isoform X1 [Strongylocentrotus purpuratus | PB0168
MSGSFRPLKLIETLYLNDNNLTTLSSSSFTHMSFLKQLRLSKNPLACDCHLSWLALWLRPHIHLGLFTTCETPRQLHGLK
VAELQTSDFRCTGNENHEALCEVEPLCPAKCECTSKSVDCRNRGLTELPFTFPYHMMELRLEQNYITEIPPRAFSPYKKL
KRIDLSNNLIETIAEDAFSGLRTLNSLTLYGNHMSDLPEAIFRDLTALQLLLLNANRLTCIRINLFRDLVKLHLLSLYDN
NIRSLSNGTFDSLRSLQTLHLARNPFICDCNLRWIAEYLESNPVVETSGARCARPVRMERKRITNMKSVKFKCKDAEYYR
TAQAGQCFIDHDCPDACTCHESIVDCSNRGLPTVPDEIPTYTTELKLNGNEISRISADGKFLHLPNLKILDLRDNRISVI
EDEAFQGASSLVELMLTNNKLSNVTGRSFVGLKNLRTLMLRSNRLSCITNETFTGLKAVRLLSLYDNAISTIMPGSLDSM
KALATLNLLGNPLNCNCHLSWLPDYLSARLIITGEPRCQEPSTLQDTPIQTLQRDQFTCEGNDHNSCLPSLACPRECACS
GTVVRCSRKELTLPPRFIPTGATELYLDSNQMITVPERLSSLKSLHTLDLSMNQIAMLPDFAFANMTKLSTLILSYNRIS
CIPDGAFMGLNSLRILSLHGNNISIISESSFSDFTSLTHLALGGNPLYCDCHLHWLSDWVKDGFKEPGIASCADPYILRG
KLLLTAPSKKFLCTEEPDISIRAKCDPCLSAPCENEGVCLTDPIERYRCQCPAGFKGQHCEAEVNECDQRPCMNGGVCEN
LAGGFRCDCSTGFSGDMCEVNVDDCKAHLCLNNATCVDGINNYTCRCSQGYKGDYCEVDIDLCHPMSDPCQNGGVCFDLG
HSYRCECPPGYRGINCTDGYEDCRTRPCLNDGECEQDGNQFACRCPQGYIGQTCEMNANIYISDTPCSCLNNGQCYDNNV
TDSEECRCLPGFYGTKCEIPTSMSFRLGQEVYVQYPAPNNPQIVNFTLIFATTIENGVLLYLGNINHIAAELFRGRIRVS
YDVGNFPAATMFNQKKLNNGEFHKLQLVLYRRNVSMSIDGGPWQTKTNAGEEEYLQVDEPMYVGGLPRHLQNFAVNQWHI
RNRSSFQGCIRAFFVNNEPKRLSDASDRMSVKEGCPNYDMPNPCLENRCVNGFCHNVDESMYRCDCQDGWMGTFCDRETT
CTSIKVNNTYEMDGCQTLRPIRNATCAGECGLSCCKPARSHMRNVRLHCPDGTTITQEIKIVRNCACQGCEGG
>XP_030847127.1 IgGFc-binding protein [Strongylocentrotus purpuratus | PB0169
MDEQVWIYRDVTSMNLVTDFLWVSYDGMDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPD
QCDGVDPGPTDPCEDGVNSLSASNDLCYYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKG
GKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYI
PSGGAWTDPGCTQHCLCRGGLAECSEFQCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKY
NFQGDCDYTLVRDCQNSSDYHLWSNNERLRPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYR
DVTSMNLVTDFLWVSYDGMDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGP
TDPCEDGVNSLSASNDLCYYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLL
VEECPLNCPSNTVYDPCFSGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDP
GCTQHCLCRGGLAECSEFQCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYT
LVRDCQNSSDYHLWSNNERLRPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVT
DFLWVSYDGMDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVN
SLSASNDLCYYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCP
SNTVYDPCFSGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDPGCTQHCLCR
GGLAECSEFQCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSS
DYHLWSNNERLRPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVTDFLWVSYDG
MDSADVYLSYFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVNSLSASNDLC
YYLKDPSGPFESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCF
SGCPATCSSAASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDPGCTQHCLCRGGLAECSEF
QCGENEECEIRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDYHLWSNNE
RLHPSDSVSYLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVTDFLWVSYDGMDSADVYLS
YFAGRTCGLCGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVNSLSASNDLCYYLKDPSGP
FESCLEIVDPDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSS
AASTLSCNTTCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGGAWTDPGCTQHCLCRGGLAECSEFQCGENEECE
IRNGFPSCYCRDGYTSLGDACFRAPGYCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDYHLWSNNERLHPSDSVS
YLREVVLDLSDRRYALIKGFHVRVNGRDVSENLPYMDEQVWIYRDVTSMNLVTDFLWVSYDGMDSADVYLSYFAGRTCGL
CGSFDGDQNNDMILPSGELARSATEFGNSWVAYPDQCDGVDPGPTDPCEDGVNSLSASNDLCYYLKDPSGPFESCLEIVD
PDDYYDSCVYDVCLTGDDALCSSLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSSAASTLSCNT
TCQETCRCADGLVLDGGHCVDPSQCGCTLDSGVYIPSGASWTRPDCSQQCTCEGGRAQCESFQCGENESCDIKNGVPSCY
CKDGYTSLGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNELLRPSDKVSYLREVTLEL
KGNIYSLIKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNFDGDK
SNDLLLPSGEVARSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPEDYYQS
CLYDVCETGDDALCANLEEYAQACRNRGGQPGNWRASVPECPLDCPSNTVYDPCFSGCPETCSSAASTLSCNTTCQETCR
CADGLVLDDGKCVDPSQCGCTLENRVYIPSGALWTRPDCSQQCTCEGGRAQCESFQCGENESCDIKNGVPSCYCKDGYTS
LGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNEILRPSDKVSYLREVTLELKGNIYSL
IKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNFDGDKSNDLLLP
SGEVARSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPEDYYQSCLYDVCE
TGDDALCANLEEYAQACRNRGGQPGNWRASVPECRKSAEMSGALWTRPDCSQQCTCEGGRTQCESFQCGENESCDIKNGV
PSCYCKDGYTSLGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNEILRPSDKVSYLREV
TLELKGNIYSLIKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNF
DGDKSNDLLLPSGEVARSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPED
YYQSCLYDVCETGDDALCANLEEYAQACRNRGGQPGNWRASVPECPLNCPSNTVYDPCFSGCPETCSSAASTLSCNTTCQ
ETCRCADGLVLDGGHCVDPSQCGCTLENGVYIPSGALWTRPDCSQQCTCEGGRTQCESFQCGENESCDIKNGVPSCYCKD
GYTSLGDACFRAPGFCQIWGDPHYVTFDDKKYNFQGDCDYTLVRDCQNSSDFHLWSNNELLRPSDKVSYLREVTLELKGN
IYSLIKDFHVRVDGIDFSRNLPYFDEQVLIYRDVTSMNLVTDFLWVSYDGKNSADVYLSYSYFGRTCGLCGNFDGDKSND
LLLPSGEVAKSKTEFGNSWVVNPEQCGDVEPGPTDPCEEGLENTREEAADVCNYLLDLSGPFASCHEYVAPEDYYQSCLY
DVCETGDDALCASLAQYARACRSKGGKPGRWRLLVEECPLNCPSNTVYDPCFSGCPATCSSAASTFSCNATCQETCRCAD
GLVLDGGHCVDPSQCGCTLVNDVYIPPEGAWTSPDCSQHCQCSRGIAECEPYVCGRNEECQLKNGIPECYCQDGYTLLGG
YCVKAPGYCQVWGDPHYVTFDQRKYNFQGDCDYTLVRDCLNSSGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLSWD
FVVRVNGIDFTNNLPYFGDGIIIFRDFNSLILITNYMWISYDGKRSADIFLSYSYWNQTCGLCGTFDGDKSNDWRLQNGE
LADSPVDFGNSWVVTVDECDDVRPEPTDPCEADLVLLADAEDLCAVLLDVDGPFAPCHDFRDPDPFYDSCKYDICALGDE
FLCDSLTQYAEACRQAGGQPDDWRSETPQCPFDCPADTVYDPCSSGCPETCSTAISSIPCNLTCQETCRCADGLVRDGDQ
CVDPSQCGCTLENDVYIPPEGTWTSPDCSQHCQCSGGVAECQSYVCGRNEECQIKNGIPECYCQDGYTLVGGYCIRAPGY
CQVWGDPHYVTFDQRKYNFQGDCDYTLVRDCQNSNGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLSWDFVVRVNGI
DYTNNLPYFGDGIIIFRDFNSLILITNYMWISYDGKRSADIFLSYSYWNQSCGLCGTFDGDKSNDWRLQNGELAESPVDF
GNSWVVTVDECDDVRPEPTDPCEADLVLLADAEDLCAVLLDVDGPFAPCHDFRDPDPFYDSCKYDICALGDEYLCDSLTQ
YAEACRQAGGQPDDWRSETPQCPFECPANTVYDPCSSGCPETCSTAISSIPCNLTCQETCRCADGLVRDGDQCVDPSQCG
CTLENDVYIPPEGTWTSPDCSQHCQCSGGIADCEPYVCGRNEECQVKNGIPECYCEDGYILLGGYCIRAPGYCQVWGDPH
YVTFDQRKYNFQGDCDYTLVRDCQNSNGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLSWDFVVRVNGIDFTNNLPY
FGDGIIIFRDFNSLKLLTRYMWISYDGRRSADIFLSYSYWNQTCGLCGTFDGEKSNDWRLPSGELAESPVDFGNGYVVTV
DECDDVRPEPTDPCEVDSEVSRKAAELCSILLNKDGPFAPCHDFRDPDPFYDSCKYDICALGDEYLCDSLTQYAEACRQA
GGQPDDWRSETPQCPFDCPANTVYDPCASGCPETCSTAISSIPCNMTCQETCRCADGLVRDGDQCVDPSQCGCTLDNDVY
IPPEGTWTSPDCSQQCQCSGGIAECRSYVCGRNEECQVKNGIPECYCQEGYYLVHGFCVQAPGLCQVWGDPHYMTFDQRK
YNFQGDCDYTLVRDCQNSSGFHLWADNEKRNPSDEVSYIRELVLEDSGNIYSLIWDFRVRVNSIDVTDNLPFFGENIIIF
RAFNSLKMLTPFMWISYDGRRSADIFLSYSYWNQTCGLCGTFDGDKSNDWQLQSGELASNPKDFGDSWVVNVDECDDVRP
EPPNPCVENSITTEEAESLCNILLNDDGPFAPCHDYLSPDPFYDSCKYDICALGDEYLCDSLTQYAEACRQAGGQPDDWR
SETPQCPFECPDRTVYDPCFDGCPATCSSASSPVPCNVTCQETCRCMEGLVLIGEECVDPSRCGCTLDNGLYLPVGETWK
NPDCSERCSCLGAGELQCESTTCGQNAECNVKNGVPECYCQEGFVLYDGRCIDGPGVCQIWGDPHYLTFDSRKYSFQGDC
DYTMVRDCLNQTDFHLWADNRRRRPSSEVSNLDKLVLDYDGHRYALMKSQRVKVDDVRVSLPFISPSRDIEIWSTGRPGN
VILQTSFGLMVKHNGQRAADIYLERSFWNRTCGLCGTFDGNPDNDWTGADGVVRQRGEKTDFANSWVVNRDECSDIIPEP
EDPCAEGGETLKQAEELCYVLLQPDGPFSPCHDFVDPADYHTACKYDLCARFPDDDYLCDSLNGYASACRQAGGAPEDWR
SETTPCAYECPGASVYDPCASACPTTCSDLSSAFNCTLPCIETCRCPDSMVLDGTECVDPEECGCTLDNNVYLSPGESWT
NDNCSETCTCMAGEIICTENTCHQFANCDIKDGIKKCYCFDGWSGDGYTCTRSQGVCQIWGDPHYLTFDSRKYSFQGDCD
YTMVRDCLNQTDFHLWADNRRRRPSSEVSNLDKLVLDYDGHRYALMKSQRVKVDDVRVSLPFISPSRDIEIWSTGRPGNV
ILQTSFGLMVKHNGQRAADIYLESSFWNRTCGLCGTFDGNPDNDWTGADGVVRQTWAEKTDFANSWVVNRDDCSDIIPEP
EDPCAEGGETLKQAEDLCYILLQPDGPFSPCHDFVDPTDYQTACKYDLCARFPDDDYLCDSLNGYASACRQAGGAPEDWR
SETPQCAYECPGASVYDPCTSACPTTCSDLSSAFNCTLPCIETCRCPDSMVLDGTECVDPEECGCTLDNNVYLSPGESWT
NDNCSETCTCMDGEIICMENTCHQFANCDIKDGIKKCYCIDGWSGDGYTCTRSPGVCQIWGDPHYLTFDSRKYSFQGDCD
YTMVRDCLNQTDFHLWADNRRRRPSSEVSNLDKLVLDYDGHRYALMKSQRVKVDDVRVSLPFISPSRDIEIWSTGRPGNV
ILQTSFGLMVKHNGQRAADIYLESSFWNRTCGLCGTFDGNPDNDWTGADGVVRQRREEKTDFANSWVVNRDECSDIIQEP
EDPCAEGGETLKQAEDLCYILLQPDGPFSPCHDFVDPTDYQTACKYDLCARFPDDDYLCDSLNGYASACRLAGGAPEDWR
SKTPQCAYECPGASVYDPCASACPTTCSDLSSAFNCTLPCIETCRCPDSMVLDGTECVDPEECGCTLDNNVYLSPGESWN
NDNCSETCTCMAGEVICTENTCHQFANCDIKDGIKKCYCFDGWSGDGYNCTRDPGTCTVWGDPHYETFDGRKFHFHGECD
YTLVRDCYNVTSHPSFLISSGNIKRNPEDKVAYINEVRLEIYGKDILLTLGGGVYLDGVSVNIPLNINSGQIYVFTSGKD
TIIRTVVGIKIQWNNRNTATITVPSSYHGALCGLCGNYDANPDNDFRLLNNVVVTKALDFGNGWVLPGVLECGVSIDEPE
PCQENDDFLFAQDACFIVLDPEGPFVPCHPFLDPTPFFEYCSYDACATSPNDTVVCDDTSVYAERCIELGYPPNTWRSAE
FCPIECPEGFISSPCVPACPETCFGTTEGEGCNDETECREGCVCPEGSVLADGECVPREECGCVFTDEELELYLPVGESF
VSVNCSRVCTCEAGANQICESMSCDPNAYCGVEEGERGCICMEGFLGDGLDCIEVTEMPTTPMITTTDLGVQSTTSDRGS
STATPANVSTTIDVRTTEMFFNVTTTASTTTEQGTDTTEFVNATTPVIVTNETTTDATTEEQTTVLGTSPVIVTNETSTD
VTTEEQTTVPGTSPVIVTNETSTDVTTEEQTTVLGTSPVIVTNETSTDVTTEEQTTVPGTSPVIVTNETTTDVTTEEQTT
VPGTSPVIVTNETTTDVTTEEQTTVPGTSPVVVTNETSTDVTTEEQTTVSGTSPKVSTIPMGSSTEAATTTDSLMTSSMA
SGATTAVVMTSEETQPTTKDGATTLGMTTDGPTTQEMTTQAQTTTPPIETSTCRIWGDPHYITFDYRTFHFQGQCNYTLA
KLCNESLTDEDRPWFDVVINNRLKVVDGSTSYLRELYLNISSHKISLLQGPVVLLDDVLQRLPYYSSSGLYITYAGRYVV
VSTSTGLVLRWDGEGGITLTLPPAYSGATCGLCGNFNGEASDDFVLPDGSLAADSTSFANGWSLEDDCSDTTQIDPCSTD
SDLLATAQSRCSILSSDAVSGFAYCQQSVDSAFFYDSCLYDVCAELPGDEGADCNAFAAYHQTCLDEGHPITEEWRTGSS
CDSACSSSNSTYQTCTSSCPETCPGRAVDPPCDTRCVEGCDCDDGYLLDSDSCVPISQCHCERDGVFYSAGTTLLSSTCS
ELCTCMSGLFMCEVASCDENASCGMDENNDPTCVCNIGFEGDGYTCSAIVYDLQVCTIYGDPHYVTFDGQDYTFQGDCVY
TLVTSDCINGTSDNTFSVTATAAKDSDTHSFTYTRELVVNVEGLAITMTTTDIFLDGVRVNVPFYKNNVYFTQSGEYKVV
MTNYDLAVRWDGVSTAEVWLSEYYDGNVCGLCGNLDGDANNDFTKPDGSEASSIEDFGDSWSDGAISCPETPTDTNPCDT
DATLRDNAVTQCSNYLNDTNVFGDCYSTVTLDPYYESCLYDMCATNLNSSVLCNIVEVYATRCQLQTDWKRNVDGPCSYD
CPANSVYSSCVTECPSSCADLGTVDQCTSLDLGCTSGCVCEEGFVYEDDQCTVASLCGCTYNGLYFKSNEEYISDGCGQR
CVCDGLSHMMSCESIQCAFNGVCEIRDGNRACYCQDSTDGATCYNATVGYTITLDQATWSTLTLTWTTDQEVTSVIVQYR
FQGEEVWSNSSTVDATRQIIILDDLTSSQSYQVRLVFVGDSFYTRSSVEVFDTCTPGVQGPECATDYSSTSAYDFNLVYA
TSASLELKWTLPEIAEIQWVHLTFRESSTDPWSNGTLLEGTATSDIIQGLSELSSYQVQVAIGLSSGEQAESAVLTLLTC
AGGTVGLNCEGDVPIDASVDTVSSDFVTVTWTVYVTVSQVAVQHRVATSPQARVLITADGWTEEPPVPADRGLYNIEGLE
PGVTYDYRLKLINDTKEQFGETNQVTLCPEGFQGANCEINYAELGAFDVRLVEAMVTSLNVTWQTTVSIVWSQVQYKRTS
DTSDAWLATNQLQPLETGALLTPLAEDTAYSVRVLVTRMDVSSTISDVVQMKTCVAGFRGLNCEIEIPVVTTTPSPTTMQ
TSPPTEPSTEPSTAGPTTPFTNAPTTVAAPLYIIETVGKTSTSLKISWTLQQPNVVQVFVEYKPNLSQTWTQVSASSPEQ
VSFTINGLTPAIMYDIRLMLVYEDSPEAFGEVYTLETCEEGFRGVDCQTAEVSPYRITLSHINSLSITAEWTSPTSVTDV
VLQYRTDSGPWNNGSVVTRARGFYILTGLDDNVAYTLRGAFAEEQSVEFSDVISAVTCEQGFAGESMCDTDYSNVGAYDV
VLSTATSTSLVISWAVSLQADWHMVQYRIDSNSIAPEWFNSTELDANTTSYTIDDLEPNETYRIRVLTRRTTTAGRKKRA
DIAENVGISAEVLVVTCQNGLQGLNCEEFAVVPTTGQPTEPPTQPPRTTLAPSSIPWRDILIGLLVVFGILLIILIFIII
LIYGKVKRRRSQMAKIQEVNDGTQRGYRQSDVLFATDSNSYSSSEVGDHHNGLDYGRDAAADPGHVRISMVGQRDNVRDA
GTSTRWMNDQGYNDGTYRYNAAYDPTED
>XP_030833101.1 fibrillin-2 isoform X1 [Strongylocentrotus purpuratus | PB0170
MMRSSLLVLLACLSTVVVAQSNVINGPNVCGMRFYSYCCPGWRLHPRTKQCVVPVCNRPCGSGYCQRPNSCSCPGGQISV
SGCDGYSGGNPCTTQCLNGGSCQGNSCNCPNGFSGTNCGMPTCNPPCQNGGECSGGNRCSCPPGFGGSQCQTDYRTGVCY
LQSTSNGYCSAGVEGLHCTKALCCATIGQGWGDPCENCDTFDNPCDRGYILNGRTGQCIDADECLMIPGLCDGGQCTNTQ
GSYACQCPAGFELSMSTLSCVDMNECQTGYLCQNGRCINTQGSFRCDCNPGYFLGQDGHHCTDIDTPNTPVTPEEIGYCY
MRFRNRNSRGTSCSQELAVRMSFLDCCCSVDHAEGWGLSRSDCSPCRTENEELYRRLCEGVGELTTPQPRRTPNPQTRTD
GPGVVTLTPPTVTPPRKITPRPEGICLMVPNICRNGLCVSLGGVMEYRCECFEGYENAGRYTCQDINECRDRSLCRYGAC
ENTDGSFRCVCPSGYKLSLDQRSCEDVDECRTNPNVCHHGTCMNIVGSHTCDCFEGYQKSIDGRYCIDVDECTLGSHRCR
NAECENLPGTYECICTEGYEAIGSSGVCIDVNECAQETNPCPLGFCINTLGGYQCQCPVGYATGQDGTCVENRRGFCFLD
GDLGRCTHQSMGQMTISSCCCSAVLLQEALSWGPNCESCPPQGTLQFEQLCKHGTGWTSQRININECTLFNNLCDNGVCE
DLTGNYKCRCNSGFQPQADGKECIDENECSYNRLLCHNGACRNTPGSFVCECPDGYELDARSSVCQDVNECQNPSLCNNG
RCINTRGSYRCECIYPGTELDPTGTICVDNRIATCWTRISNGQCEADIMGPMRRDECCSTFGRAWGSPCEACPLAFGDCP
RGFSEINSECVDLNECELNPMVCNNGLCENTMGSYRCVCEEGLTLDTSGRNCVDLRSYECFLDYSEGQCSSPIPGLYRNS
VCCCSLGYSYGDQGRCYECPQEGSVEFDVLCPRGRGFADTRPRPDLLDGTVYINDINECNAYDGICKYGECTNIIGSYDC
VCDVGFAMDEFGYQCVDIDECRITFGACGNGSCENTPGDFRCNCYEGFEAHPVMRSCMDINECETVPGLCRGGSCTNLPG
MFRCDCPLGQELTPDGQACRDINECSISTGICSNGECHNIVGTYRCMCNPGFRPTANYRACEDMNECDMDNGGCDHNCVN
SQGSYECQCQSGYSLRVNGRTCVDIDECADNPDICGGGQCENQEGGYLCDCFVGFRPADDFRSCLDIDECSTDAGVCVAG
VCKNTRGSFTCQCFEGYSMKPGIPGCSDIDECMLQMHQCAINSQCENTIGSFQCRCNPGFIVDENANICIDVDECESSNH
DCHEDARCVNIPGSYQCQCNQGFIGDGLSCIDVDECMQNQALCVNGQCINNPGGYVCECEMGFYPTERRDSCEDIDECSN
FPDICVFGQCINVPGTFRCECNPGYMLDIGGGNCTDVNECEDPGTYCVSGLCTNSMGSYVCECPPNWVLSRDGTTCADVR
TGLCYAHGPGAESRLDVNECSLLLGTSIPRTKCCCSELGKGWGDPCELCPLVNTTEFFLLCPYGIGVHIDPNATRPVNEI
NQCRDFPNICRGGECQQVEGSFRCVCPTGYEYDFEQMMCIDIDECQLSAYICGAGTCMNMEGSYTCMCPMGFMFMNMPTG
KNCMDIRELTCYMSYNQSAFPLPECGSPLMTSLTKKVCCCSALMASAWGTRQECSPCPAHMTEDYYRMCGATSPGFVVNP
ETGLPEDVDECRLIDGICANGICVNTPGSFRCDCQPGYRANMATHICEDIDECFEGMHRCVGNSICRNTPGNHECICPPG
YQLSVSRLSCDDINECLTRPGTCINGQCTNQIGSFVCVCDQGFQLSADGTQCNDIDECFRFPDRCGNGTCQNVVGDFACS
CNRGFELTINGDCADINECATMQGTCPNGRCVNTPGSFFCDCVEGYVLSLSGLRCEDENECISRLNICQNGRCDNTIGSF
RCSCFDGFQLSPSGQECIDTDECVIIPDMCRNGVCQNTQGSFQCTCPPGYLLSSDGLICIDMRRSYCYNDFVGGQCTDAR
AGNATRKECCCSLGAGWSSPCNLCPRPSDASFTELCPDGPGYAPSLTPDLYEDINECKVFPGICENGICINTDGSYRCQC
QPGFILDTTGRICVDRNECQENYNVCGFNSTCYNTLGSFECNCGEGYQVGRRGTCEDINECRRRRGQCAFRCQNLPGSFR
CLCPNGYTLTDDGRHCRDLDECDTNLNTCRYRCKNLIGKFMCQCDEGYTPIGGDGNNCRDINECITNHGVCQNGRCRNTE
GGHTCICNQGFTLGPSGKDCIDRRTGFCYAYVPPSGCESSQGGMQPVTMESCCCSGGRAWGSTCQICPVYGTIEYNRLCT
ATTPVDPCQIVQGLCENGHCLGGSGGYLCQCNPGYILSPDGTRCEDENECNRAPPPCSYQCKNTPGSFRCGCPQGYLLSE
DGLTCREKDECSMGIHECQFECRNTLGGFRCVCPEGYIQHGSTCIDVNECIQTPDICGAYGTCQNTQGGHRCECQRNFRP
DPSTNTCVDINECEDQPDICQYGCQNTIGGYRCVCPDGFEENFYGRCIDNNECRQSGKCGQATCYNTQGSYQCGCNNGYA
FDQQNLACNDVNECQGSYGNTNSPCQYSCDNTDGSFSCGCPPGYTSVVQGACVTDRDSVQPCYSCNRQPRQRRSATETND
KESTLISNNTAILYHIPLSKAVPKQQIAKFKTGYTRIVARYEYVILSGNEDNIFMMKKKSDGMSLLRFSKHVKATGLYEL
EIEGVLKRKNDTILAEVQTVVEEPVAMQIQVQIVADEEE
>XP_001197113.4 serine protease HTRA2, mitochondrial [Strongylocentrotus purpuratus | PB0171
MAASMYRQSLKLSRLIRSNTPLLWRYSPTVNPQSTQVVISRTITQNQMHENQKIFFKRVAQFVGFGVFLYVISPWARQLK
GAKFESRRDKKRRRLAAEQNEVENTSISHGVPSLNYQESSPPSRGILPVVKAADVTDFGTGYVTPRSQQFNFIADAVAKA
SPSVVFIEIHGRHPYQRGVVGPISNGSGFIVSPDGLILTNAHVVANKRLGKQSVKVKLYDGRLVDGKVVAVDPVSDLALL
KIDTKDPLPVMRMGNSSAARPGEWVIAMGSPLSLSNTITAGIISTVSRTSKELGLNKSIDYIQTDAAINVGNSGGPLVNL
DGEAIGINTMRVTTGISFAIPIDCARDFVDKVQKQMKASGGGWFGKSGPQGPALTTPSKAGKQGYIGITMLSLTPSLIFD
LRQRAPDFPNVSHGVLIYRITMESPAQVAGLKAGDIITHINDQPIKSSQELYDRVQAKESLKVTAVRGKETMKLTITPEE
SQ
>XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus | PB0173
MDLLYYMTVSLLGFILSLTTFIGETTRALSDDVSSPCKASGFLGDIALTEDDYEREMIRARHNREQYRRRILQERHTRTT
GARHHIKKRTIEEAKVRHVRAVTARPERRWTDAVIPYEIDGNFTGSQRAMFKQAMRHWENYTCITFVERNPANSEHDNHI
VFTYQACGCCSFVGRKGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNIVPGQEYNFRVLDAAE
VDSLGETYDFASIMHYARNTFSRGIWLDTILPRKDPESGIRPEIGQRKHLSEGDIIQANLLYKCPSCGRTLLESTGNFSS
PEWPGQYDGDQTCVWRISVTPGETISLQFTGFELVGSDGCWYNYLEVRDGHWRHSPLLGRFCGASLPDPILSSDSRLWIE
LKSSAHRYSRGFAANYEAICGGHIERESGTLQSPNYPDDYHPSKECVWLITMPANYTVGLSFQSFEIERHETCIYDYVEV
RDGHEDTSPLIGRYCGYFIPDDIKSTGNKMMVTFVSDGSVNKGGFSADFFKEKDECAQPDQGGCMDVCVNTIGSYRCDCR
PGYELSSDGRRCEVACGGLFTGLRGNISSPSYPEPYPRDKNCVWQIVAPSNYRISLQFITFDLEGNEVCKYDYVDVRSGL
NEEGTLHGKFCGNEIPETITSRFNNLRIDFRSDNTVAKEGFFANFFADVDECEEGNGGCQHICTNTLGSYTCSCRNGFTV
HENLHGCKESGCRREIQSTTGIITSPNYPDNYPKRKECTWHISANPGHKIVLSFDDFDLEQHQECTYDRVQVFDGDSDEG
QVLGRYCGATIPDAVVSSSNHMFIRFYSDASVSRSGFSATHSTQCGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIV
SPDDHFIHLWFRSFDIEHETECNYDQVMILDGDNHAAESFGKFCGHRAPDDIVSSGDSLMITFSSDDTINKKGFLAIFKL
TDGELLEGAGEEEEEIYYN
>XP_030844513.1 trypsin-2 [Strongylocentrotus purpuratus | PB0174
MLKAIVLLSCVAAALADCGKPAVDPVNTFIVGGDAAMPGSWPWQVGIRKNYLVGQGGYHMCGATLIDNQWIVSAAHCFYR
WKRLSDYTITLGSHDRDEVDSTQVNAKLGGIFVHEDYNSMTLDNDIAMLKLETPIDFNDAISEACVATSDYPADTMCVVT
GWGDQEAAIDNAELQQVYVPIIDTKVCNRPSWYNGEITDNMFCAGYSSGGMDSCQGDSGGPFVCKNSAGAWELTGVVSWG
YGCADPLNPGVYTRVTQYNDWISGIKRNN
>XP_003730975.1 leukocyte elastase inhibitor-like [Strongylocentrotus purpuratus | PB0175
MGNCAVVCGSEYIRDMAFSEQQDTSGQLVQLSSANIGFALDLYQTLQDERRGTNLFFSPLSISTALAMTQLGARGDTATQ
IADIFRFNQIDQDKLHGTFKELNNLLYQTDSGYKLHSANRLYGKSGYNFVQSFVEESASYYGAAIEAVNNFAAPITTQSI
NDWVSKQTEDKIKNLIAPGILNDLTRLVLVNAIYFKANWQSEFLTFDTTQDTFKVFDEREKVPVSLMIQEGRFALAVDNT
NDCLVLEMPYKGHNMSLLIALPTKDDGLGQLETKLSVDVLQSWDAGLKSRKVKVLLPKFKLEATFPLKEVLKRMGMPDAF
DEDRANFEGISGDREFHISAVIHKASVYINEKGSEAAAATAVMMLDGCPLPSERKKLFLFRADHPFLFMIRHRSTKSVLF
MGRMMDPS
>XP_030846390.1 growth/differentiation factor 8-like [Strongylocentrotus purpuratus | PB0178
MAQLNHYVYLALVIVEFVCLTIASHPPSWRRRAGIIPMSAHQQPDEILAENTSSDVHADDGSPDPDLTSASNGSEDAMTP
PPELSTCPPCWLREQQKQFRIESIKRRILEKLQMTHVPNITGPPPKNPAIKNLLQNYPQYQNNPSVQSDSPQTEYIDPAP
AQLERILIFAKRPLQTHGTDAPSCCYFNVAEKIVGYHVSSAKLYFYVSPAKVVQNTLHQMTIKMITARLHPPGQTKLRLV
ANIKVQLSLRVGAWRSVDFTNVVQGWAAEPETNLGIVLELEDDAGNSVLITETSTEEPRRPFLQLRLDDTRRVRMKRQSE
QMCAEDRLERECCKYPLVVDFQQFGWDWIIAPRTYDANYCSGSCPDHYFYRYPHTQLISQMDRLAVAGPCCSPSKMTSVS
LLIFDEDGDIRNAELQDMAVEKCDCA
>XP_030839062.1 uncharacterized peptidase C1-like protein F26E4.3 [Strongylocentrotus purpuratus | PB0183
MASSSLIITSSAVLFLLTLAVLFAAVPADHHTPRYCAVRGCCNVTGAITISEAVARTGIARNDKCHAPYPTSNPTTLCYC
DGFCQRNDPDCCPDFYEVCLGQIPPPEVILDASKTETILLCCHEGNDYQVGEVLRINCNTCTCKPVLYEFATFVCEQRDC
AINPEAFGEINDGNFGWSAGNQTEFWGASKDDAMHYRLGTMKPTAAVLTMHQIQNDMPPEAIPEEFDARAQWPGLVEGVQ
NQGNCASSWAMSTAATASDRLAIQSNGTFKYMHLSPQHLLSCNVKRQQGCAGGHLDRAWWYMRKRGIVTEDCYPYLSGTT
SDMQMRKGNCYIKGRDRVPPFCPNPTIRSQRFMSTPPYRIAQDEQQIQAEIFTNGPVQAVFNVKSDFFMYNGGVYRHVPM
KTTSPASNVVFTGDQTNVQADGPLEDELGGWHSVRILGWGVDSSYPNRPLKYWLCANSWGTAWGEQGLFRVIRGENECDI
EKFVVGVWANIDTDMMNPIKTNNVI
>XP_030853763.1 laminin subunit gamma-1 isoform X1 [Strongylocentrotus purpuratus | PB0184
MKFLLVLGMVALCRANQNSIPCYDDLSRPQRCVPEFENAAFNLSVEATNTCGEYRDTRYCRQTGVQGGARGRGQCYNCQS
GSHPARYLTDFHSEERMTRWQSETMYEDIQYPNSVNLTIHLGKSFEITYIRLKFYSPRPESFAIYKRTCQDCPWIPYQYY
SGSCRGTYNLPDSEYVSYDDETLALCTSEFSDISPLTGGNIAFSTLENRPSARSFDNSAVLQDWVTATDILVMLTRLNTF
GDEVFRVPNVLRSYFFAITDFSIGGRCKCNGHASHCVEAPNDPYNRLVCQCEHNTAGPDCGECLPLYNDRKWTRATAGNA
NECMRCNCNFHADRCFFDEELYNRTGSGGHCMECRDETSGVSCERCRDNYFRTSPDARCQPCNCDQTGSLNQQCDSSGRC
QCKVGVGGDKCNQCLPNFYDFGEGGCRSCECVRAGSVDNNPDCNQGTGLCNCKLHVEGRDCETCKPGFFNLQEADEFGCL
PCFCHGHSSSCSSAPGYDIAYIESNFNSGVDGWKAESRNGDQELLVYNAIRQDIGIATVDNQPMYFIAPDEYLGSKLFSY
GQELSFKLRLGSDDVSLSVEDLVLEGGGRQISAPLVAQGNPRPGVYPQKFTFKLRAEDDMGWVQRPSAFEFQSLLSNLTA
IKIRATYSDRGQGLLDDVRLVSGRRSVGPQSTRATFVELCSCPTGYVGQFCESCAAGYRRDPYGNGPFTRCIPCECNGHA
DYCDVDTGECICNHNTMGTSCELCQDGFYGNALEGTAYDCTRCPCPGGTNCFVDNLGDVVCTECPSGYVGNRCDYCADGY
YGDPTGIQGQRTACGQCYCNYNIDPNSVGNCDRFTGECLKCVFDTGGFYCENCLPGFYGNALGSPKGEQCQACNCYVSGS
TSNECDQSNGQCSCMPFVTGRDCSECEAGYWNIDSGRGCEPCYCESTGSTSDQCDIRSGQCPCKPGVDGLRCDQCQYDHY
DYSVEGCTPCECNPQGSLYANCTDDGVCDCQPGVIGDKCDSCEENFYNIALGCIPCPECYNLVRDNVNVHRDNLDALRDK
INQISSNPTVINDTDFEMRLRELEGLLNQTIDDAQRVTAEDRTLADNLNAIKDDLGDLRLALARIRAKIDQADGVTEAAK
QDVAEAMAIINRLKRMLPSAQEYLDNEGWALLEKLRGLTANMSAQDRLMQEIAREAKQLADNHTEMALMVEETSARALEI
AYLALDAARDSGDGGDLEAMVEGVERKYVDAQELFNQASQAADECFERAQRAAEEALRLLTKANMPLSPIDVNSLLDAAN
DISFRARQLMDEANALRRENADLLAQVAEDARTAADLLDQAVAAENLIDLLLAKADNARSIALEAKRKGDETLQEAKDIL
RVLQGFNEEIEESKQAADDAKLRIPDIEAMINQANITAHNASDAIAAAEGDAMKARDYARMAEGNATLASEAARGVRTDA
EATMLEAQEQNDRADDLAADAMETMMRLNAIEGQAEDDGDMADRAQEKANAAKQVTGAALQAAEEALAQLQMIKGELDSA
GSIDLERLQDLEDELLNVNATITYDLRLDDTMDELRAYAMQQAGWISAYQFDLSEIRAEVANVEEIRDALPEFCPNESIL
EP
>XP_030827829.1 leucine-rich repeats and immunoglobulin-like domains protein 3 [Strongylocentrotus purpuratus | PB0185
MATYSSQIFRCFYTVLVVYCLLLDTAKYVSGQNVLCPEECWCLGSLVDCSKRHLTSIPTDLPTWVTMLELQSNRIASIPD
GTFDRLSQLEDLDLSSNKLRRLNASTFDGLSNLQQLKLASNKLTSLPILGPSARNLTQLILHHNRITNISPAALRGLTSL
RTLDLSYNRIGHLRTDTFPTDNRLQFLLLENNRISTLQQGCLNNLRSLEILKLNRNRIASLPRDLFTHLESLNLLELSRN
ELTTVDSLVFSGLESLEELSLSRNQLTDLMDGAFYGLNAIQQLELDGNELTTISRRWLFGLKSLLHLTVAHNRINETEAS
GWEFCPNLEYLDLSHNRLTTLETEEESVGESGGPAAQGTSGGAPGSVGVPPWPPLLRELYINHNRVTQVADGAFIQLNLL
QVLDLSDNVIAWTVDDMTGAFEGLESLLRLGLANNNINSISRRAFSGLVNLQSLDFAGNVITTVENNAFEGMPQLTQLLV
NSSSMVCDCQMAWFPVWIKENNLGEGVDGRCAHPDTLQGLDIFSVDPEVFTCDDRLKPFIIREPETVTSLKNDNVSLICT
AGSTSDVQVTMLWKKDKAIMEDANPIYFERLNPSGVNEYTSVLNLPHIKEADQGRFQCIISNEFGVTYSKKARVTVHIYP
SFTVTPRHVSVRVGGIAELPCAATGHPTPKIAWQKDGGINFPAARQRRIKVKTELAEFYIDNVQISDTGVYTCTALNAAG
TISTNATLTVLEPPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDEEPFTLSDGMHLTDFDRYLIIMNAAGRDGG
TYTCEATNSLGVRTDTAKLVVTQNSGTVWNMTTTSIIIVVVICCILGTSLIWVVIIYHTRKRTSRYRVEESHHHVVPPEI
PSSTLNGSSEGTIHQETSSGVSSAATDKYQDDNASDCDSLDGPVGKLSTFRFSNQVRMAAIFPSETKVIQPPELAPCPRQ
HHCNIQDGPHQSGMERYCPSDSLSEADRTTLERRGQLTALPCCNGTGRSLDSAINKHMYLHHGGGGGRNHPLRKGGSDGE
EGEIEEEDEDEVFMDEATRDRLQRERLLTNSDEGLGSQTASPVNRHNYRRSNHPPPQCCHSYTSVSSPEGRCTSPSSFNI
PHENAQRGDAYSRMAMSSSSLPCNGRIPNVHLYENPTSSTQDKDLIDGHLCRSHNHVNNVNNNSNTNHSPVADPIRQSHS
IPTAISSTGNVSPGIGALLSPTTPPTTTHQVQNGHLHSHHRPHHPNRHNEKPTHQNSRKSGRHPEKHHVKSKTSPKSGQS
IPRTSYLPSSNAHPAHHVTSPTLTSLTEA
>XP_011679764.2 collagen alpha-1(I) chain [Strongylocentrotus purpuratus | PB0186
MAKSRFPWLTCGLFFLLVLIRKVHLSAIYPNNTTEYEAATKSHKYETFTAAPFTAAPDVTESSSSSTRRKDVTTSSPSPS
TQLPTSNTPYANATETYWEELPTIEVEFTTELTFTETVTEIVVEGEESYDIRTHAPASGGLKQYTANSNVSLSQGVDKGR
TLQNGSGLFLSEDVLSTDATPTLATRRPSLPKDSPETLIALTEAAWGRLGFTREAMDSPLGEFFKYYSVFPYADEKGFTR
TWNIRGDQGPRGHPGRRGPMGSMGYYGNRGPPGEKGRQGSPGPDGETGRRGYRGETGPLGYHGNHGQPGFPGIKGERGHP
GIHGYSPKEGPKGHAGIPGPQGLLGPPGEKGDIGPAGGRGEKGTLGLRGEQGHPGPQGVEGPQGIHGVGGSTGPKGSSGD
KGAPGPVGPPGEIGNDGSMGPSGLPGQRGFQGFPGIRGSPGKPGLDGQPGMNGYPGNVGPQGEDGAIGPIGESGPIGTHG
PKGQPGDQGLQGSKGEKGSRGRRGSQGDEGHRGPPGDLGMPGQAGETGDEGVAGEEGDDGVPGRKGDHGPRGLIGETGVK
GPPGPHGSKGPRGANGPRGELGPKGQTGDQGRPGGHGHRGPEGSKGKDGRRGKKGDEGDQGGKGEHGIPGVSGEKGAVGP
PGRIGTTGPVGPAGDGGIPGRNGPPGLKGHQGFDGSPGSPGPPGPMGPEGNTGQKGRPGQAGDPGAVGIQGHGGENGPTG
LPGRKGSTGEPGLLGPAGEQGGRGQKGTTGEKGSVGKRGIDGALGDEGPAGGEGIDGLPGPPGSHGKIGLMGLPGIPGYF
GQSGGKGEKGEKGKVGSDGRDGDRGSRGTRGPHGELGKQGSAGNKGLPGIQGLQADRGDSGDSGPTGSYGVTGEKGMPGF
KGESGIVGKPGHNGYSGDKGATGERGRKGDPGYRGNQGPIGRQGINGERGDSGPAGERGLHGLHGTPGEPGTAGYQGTQG
TKGEDGDQGPTGQLGEGGTAGTSGYIGVPGPAGGPGEPGLAGDDGAIGEDGLPGPQGPFGLPGNLGHHGPPGPKGPLGPQ
GPQGLMGETGLLGEKGLPGTRGRPGSKGQQGTNGWIGEAGSPSPPGLPGTDAPKGQQGTPGLEGVKGSLGYAGRNGERGP
RGPPGETGETGNSGPRGFTGQIGLTGTSGNQGEMGPEGPKGPLGNLGDQGGNGEPGILGLQGFKGPPGYLGDVGDLGFRG
VKGRIGEAGSIGARGPAGFPGLQGILGQFGIQGPRGDMGEKGRLGDPGYPGPPGSPGGYVGEFVNDADALASLLHYFFVL
PRPKHIGDVDVIHMMKYLYRYIEGMKHPLGTQDLPVRTCRDLLDCQPDMDDGEYWIDPDLGCCTDAVKVYCGLAAGGYTC
LLSRDTSTLDYDISKPQLNFLHLLSSTAFQEITIHCKNVPVWRNRRGGYENALTFRGWNGVFFSYTGQRPEILEDNCQLE
DSKWRTTRFVFRVHDVHRLPIVDIVTDPEVHRISENHGFKIEIGHTCFD

>XP_780837.2 metalloproteinase inhibitor 1 [Strongylocentrotus purpuratus | PB0188
MASYLKSSSSGIMRCCILVTMVTSALACMCQPSHPQQQYCKANFVLTGHVLEKNPIDDIQLRGRFGQFEYVINVDKIFKE
NENLKKGASGFPLSILTSPGDSLCGPKSLKIGTKYLIAGSVVDGELHISACDWIQEWRDVTQQQKKGIKNFYSAYCSQCT
IQSTMGGFRQTGGGAAGGCIYDPAPSMVNGVEDCQALYATCIIQQGQACQWYHRGNDYQDCINRNKPYYHGVETTQSVNF
PIMDDVMT
>NP_999798.1 amassin precursor [Strongylocentrotus purpuratus | PB0190
MKYPTFFAPFRALMTAVIICLFVETSKCQEATPLGPAYMRTTSGVVETSSGRCQCETAFPPLVTCQDYVETGYPERLEAA
EREIALLGHQLEEYNHTVIRLHIDLELADSQLNVTMMTLEGVLDGTVVVTVAELELVKEELKEMSLLLERIEEVASEIPE
VQQLREELNNFTELIKQLEVTRPTEVRVLQRKIDDLKSKLAECERYTRTEDESLFQPWSDFPSQDSCRDIIHVSEPFTVR
GVGNKIGAWFRDPLQDYIKVYYAPFHNPRLTYQVDRFAHVADFRGGTEYEHRYMLPTNLPAQGPGMVAYNGSLYYHAFQS
RQIVRYDLENHTVVTTGEISDADINIRGSPSAIDLAVDELGLWAIYASVSDQTNTMISRLDPETLDVIETWVAPFPKYQA
GSCFMVCGRLYCLSSFFSTDSTVELVYETSSNVFRVIDVLFDIRFGEMMSLKYNPRDQKLYGWDNGHQVVYDLTFDPPAR
SQLLPTDTNIPLNLQ
>XP_030835975.1 follistatin-related protein 5 [Strongylocentrotus purpuratus | PB0192
MRILSVGVLIAMVLTCSVEARPKRHRSHHHTKKASLDAWHVNDVFPDPNTDACSHVECPKGSECLVNRTTNLAECICRPY
CKPHYKPVCGSDGVMYENHCELHRASCVSGQRITVHSHGCDTPQTAFVMTTTPEGPIPSMSPTEAPDTCTPEEMAQLKEE
LIAHYREQFHNPNEDNDLPPLNKKYIVSLILNHYDIDADDAISRQEMESAMTLDRITDLLPGCSFLDVLDSGDFDGNEKL
SGMELYREFNIKAVSLSGSIAQRVTVAKVGDNLALPCELSSDHPLEIRWTRNNAPLTEIQEYQGIGFYAGDTSLYLTAIT
LMHEGSYACYAEGYEEVKQTHLLQVQVPPSVKICPHSQLRKQGSKARVQCHAEGIPTPQKSWTRNDIPLVQSDRIEMQNK
NSSVLVKEISYPDTGIYTCTATNPLSEAHQSASVFIQPQDHPLSPGPLHVFYLFHRDGIQTFEPDTCGFRLALTGASTLP
DTIKTLCSVDQVSETRRCDWGDAVSVDDRYIYASQPYENRVVVLDARSQRIIEVISTDGQPVSLQYVEHVDSLWVLCRRS
EEEAKAGRQSIMVIKSAGQPGPHHTIHTEPVGHTFELVEGLFIPREQIPKQGTMNFGYIVHHNQLGLHKIDLVRMERVAL
IDLTAYNCHPEALNFVAIGGSVVINCAGSETVPAKQLVLDYLTDSVIKVNEGIRGRPYVSPDGRYIISVDANHQYVHVQK
VLSESGKIKTAFEVKTNLRISDVGFFPSKTSHTYDVFATSRDQPDVLFIDLESGFVKTITGVQTPIDDEDWPWDSRNRRI
VNSGFFDPYLVTPAANHEIVINGLLRKVHCDIEDIAVANVIVWIGKC
>XP_011677256.1 amassin 4 isoform X1 [Strongylocentrotus purpuratus | PB0193
MAFSRIMISPAALAMLFIVAFRCMSNANAQCNEYAHVNSSVTENGDCVCGVTSSLSSSCGSGVSSAEFQQMIRDLDQQVC
TIVDINVELITLRVTFNQQGEDIIAMHEQMDNINAIKERIIDNKIVISSPEYDVIRMDLQDMETLISYLEDQNADQFIIV
KLREEIANISYNLDSLEVNNDGDIESLLRDIADLQQQIAECEADNDPDSEIGFPYPWENFETKDSCGTIRGLSEPYTLRG
NLASTGVWFMDPIVDVDRPWYQVGVTTASSILRYLSIEQFQTEGIHETYLPGYTLEGCSVVAYNGALFYNMYGSATIIRY
DYREGSVTNQRALPNAGYKTNYVYLSGGYTSMDFAVDEQGLWVIYGKSTNSGLMSVSKIDPLTLEVEETYNTNTLKANFG
ECFMVCGKLYCTDSFNKHDGRIVMMYDTTTQTSTTLNVPFDSKYLATRALKYNPRDQRLYAFNNGHALVYEIEFQVDE
>XP_030854983.1 kielin/chordin-like protein [Strongylocentrotus purpuratus | PB0196
MALPSAVGEAERGNVRFEDSVQGCSSWPTMTWSMAESKMNLQVRSSTANSINLSWNSFLPIDGTSTQGHYVVYYTTTFSN
HIQSWLGQIEAGNETHTSIRNLKDGTDYYFRVSYRIPGRGVHLEGHLSEVALHRTGTPAPLGGCEHDSRHYDEGMTIHQS
CDSVCDCLLGSWICRPRGCPPKPDVRINPVNCREEPHPDDPECCTMIKCEEGSNDSIQPADCNDGGVLRVHGETYYHECD
EVCFCDNGVSDCTRRCPDAGQMIPDLQTCPHPTLLEPPEGECCPHWSCPPPPNSCELNGNTYEDGEYFDVDCSMRCQCLG
GSVRCVPRCPVSFAVSTVNCPNPTRVQLPGECCLQWECEQPAEQVCIHNGEFPRH



>XP_030827829.1 leucine-rich repeats and immunoglobulin-like domains protein 3 [Strongylocentrotus purpuratus | PB0197
MATYSSQIFRCFYTVLVVYCLLLDTAKYVSGQNVLCPEECWCLGSLVDCSKRHLTSIPTDLPTWVTMLELQSNRIASIPD
GTFDRLSQLEDLDLSSNKLRRLNASTFDGLSNLQQLKLASNKLTSLPILGPSARNLTQLILHHNRITNISPAALRGLTSL
RTLDLSYNRIGHLRTDTFPTDNRLQFLLLENNRISTLQQGCLNNLRSLEILKLNRNRIASLPRDLFTHLESLNLLELSRN
ELTTVDSLVFSGLESLEELSLSRNQLTDLMDGAFYGLNAIQQLELDGNELTTISRRWLFGLKSLLHLTVAHNRINETEAS
GWEFCPNLEYLDLSHNRLTTLETEEESVGESGGPAAQGTSGGAPGSVGVPPWPPLLRELYINHNRVTQVADGAFIQLNLL
QVLDLSDNVIAWTVDDMTGAFEGLESLLRLGLANNNINSISRRAFSGLVNLQSLDFAGNVITTVENNAFEGMPQLTQLLV
NSSSMVCDCQMAWFPVWIKENNLGEGVDGRCAHPDTLQGLDIFSVDPEVFTCDDRLKPFIIREPETVTSLKNDNVSLICT
AGSTSDVQVTMLWKKDKAIMEDANPIYFERLNPSGVNEYTSVLNLPHIKEADQGRFQCIISNEFGVTYSKKARVTVHIYP
SFTVTPRHVSVRVGGIAELPCAATGHPTPKIAWQKDGGINFPAARQRRIKVKTELAEFYIDNVQISDTGVYTCTALNAAG
TISTNATLTVLEPPLFTRQMKDLTVEVGEPAVLECNVEGSPRPSIRWFKDEEPFTLSDGMHLTDFDRYLIIMNAAGRDGG
TYTCEATNSLGVRTDTAKLVVTQNSGTVWNMTTTSIIIVVVICCILGTSLIWVVIIYHTRKRTSRYRVEESHHHVVPPEI
PSSTLNGSSEGTIHQETSSGVSSAATDKYQDDNASDCDSLDGPVGKLSTFRFSNQVRMAAIFPSETKVIQPPELAPCPRQ
HHCNIQDGPHQSGMERYCPSDSLSEADRTTLERRGQLTALPCCNGTGRSLDSAINKHMYLHHGGGGGRNHPLRKGGSDGE
EGEIEEEDEDEVFMDEATRDRLQRERLLTNSDEGLGSQTASPVNRHNYRRSNHPPPQCCHSYTSVSSPEGRCTSPSSFNI
PHENAQRGDAYSRMAMSSSSLPCNGRIPNVHLYENPTSSTQDKDLIDGHLCRSHNHVNNVNNNSNTNHSPVADPIRQSHS
IPTAISSTGNVSPGIGALLSPTTPPTTTHQVQNGHLHSHHRPHHPNRHNEKPTHQNSRKSGRHPEKHHVKSKTSPKSGQS
IPRTSYLPSSNAHPAHHVTSPTLTSLTEA

>XP_030841982.1 slit homolog 2 protein-like [Strongylocentrotus purpuratus | PB0198
MKIIVVFGIVLVALGTSCAQGIGDGECPRLCNCYGTTVNCRDRGLHEVPRGIPPGTERLYLSENNITVIQRRDFDGLQSL
RTLHLMNNYIVHIERGAFTDLITVERMRLNNNKLQSLPELSFSRMENLYKL
>XP_030838146.1 leukocyte elastase inhibitor A isoform X3 [Strongylocentrotus purpuratus | PB0199
MAFHITMVTLLTLGMMGSEVKAVEVGEHTQQLARANNAFALHLYSATRATHPDQNLFFSPLSVSTALGMTHLGARGTSSA
QMSEVLRFNLLEEEHLHASFKQLNALLYESSNKYTLKSANKLFGKAGADFLQEFLDNTGNFYNSAFEAVKDFAAPEARTM
INDWVAKETEDKIQNLFPDGVLNSLTQLVLVNAIYFKSNWVKSFNRDDTEPGVFRMKDETAHLPMMFKDGEVMMTDDKER
KCFVLEMPYDGEDLSMLAILPWDDDGLANVEEQLSMEVLDFWDSDLEPENAMYWVPRFKLEDTFSLSSILQSMGMADAFD
ATKADFSGMTGDQSLHISEVIHKAFVEVNEEGTEAAAATGVTMTKRSISKRYRLRFDHPFLFLIRDRRTKAVLFLGRLVD
PPHDIRVHHEEL
>XP_030855505.1 transforming growth factor beta-2 proprotein-like [Strongylocentrotus purpuratus | PB0201
MFSSSSTSSSIRCCLAASWLGLAVLSLTFDGLGAGGQCKFDLQEYQDRRIAAIKGQILSKLGLTALPTDDGPEDVPKDIL
DLFNQTVTLLEEKYENEREQCKGLSGGSDDYFAQLPILYGIVETDIEKDIGNYATVKRLSKFFRFDLTSFEEDSQGDEVT
EAEFRLYQVPNEMKDTEQQIDLFQLITSYNSTEEPTRRFLTSWTVSTTREGWLAHDVTDVVREWVADPETNLGFELNLNC
GDYLLGPTTTTPASIPKDQHKLHVLFADPRGTFPSMDNGRGDGNPRGEGFPSINHPRLVVMTPANHSRGSESNSVRKRRS
TSYSGSQCDQNSPNCCLRPLVINFRRDLKWNWIRQPRNYSPNFCAGSCPYILSADTSHASVLSLYKHLNPDASPSPCCSP
QTFKPLTILFYNRGRPEIRQLNNMIIETCRCS
>XP_791696.4 collagen triple helix repeat-containing protein 1 isoform X1 [Strongylocentrotus purpuratus | PB0202
MALTGRMLIALSLVSLLLLLSMAEVNAWGASCSAGKPGPPGPPGPTGPSGSPGDGELLEYNNWKQCAWYSANGNDYDTIY
TCTFTKRVSDSALWVYYGGNIRLYGCSGCCKRWYFTFNDNECSPTPIDGVVYQANTNNMNLHRHRSISGYCHTIGAGSIN
VKFLVGDCSGYGNYDAYTGWNSASRIIIKEVPKSSYGY
>XP_030851691.1 CUB and peptidase domain-containing protein 1-like [Strongylocentrotus purpuratus | PB0203
MRHLFDTSICGTRPAYTLGQSRIVGGINARPGEFPWIGSLRENDGSDRGTFFCGATLITSQWVLTAAHCVTYYVDRVIFG
NLRLSGESEYEVNAEVADIIIHPDYDGETIDADIALLRLTEPVSFSDYVRPACLASSSNELSDYRRCLVAGWGTISEGGD
IAETLQKAVVNLLDQEWCDSDSSYNGTLTDNMLCAGYERGTIDTCQGDSGGPLTCEGDDGRWHLVGATSFGYGCARPLFP
TVFTRISQFQPFITAVVLGAYSPGIYEIDLDDGVPTSIASPNYPMNYDTDDVIVWKISAPVGRSVRLDVVEFFLETNYDY
LYVGSGPFPQSSTELAIMTGYVVSRSVTSHGRHMWMKFVSDESYTDAGFEVELNSVDPRDDNPVIFVEAYMPTNTVQISS
PNYPANYPANFYNIWRIVAPANYTVLALILDVDLGSGDDTLIEIGRGTSPHTGTILQTLTADDYILGIVSSPNNALWIRF
QTGNQPSGRGFVMQAVAERLADVNECERDPCRNGGSCTDLIDGFQCSCLDGYKGKHCTQDNNECRFENPCYNGGTCSNEF
RNFSCDCPEGYMGLLCEINVEKDM
>XP_030848086.1 matrix metalloproteinase-24 [Strongylocentrotus purpuratus | PB0204
MDEETRRLMSYPRCGMPDVIPNGDPGQTRFRRYSDSGDKWDHQEITYRILNFTPDLTEAEVVDSFERAFKVWSDVTPLTF
RRVFDVPGDIHIQFSEYDHGDGVAFDGLGGTLAHAYFPGGSIGGDAHFDDSEIFSVFLSDDDKTDLFMVAAHEFGHSLGL
GHSSDIHALMAPFYVGYDPGFSLGYDDLHGIQSIYGINSSPRPGDRFIPLRPQPSPPDPEVERCSKSFNAVAFIRNELFL
FKGKNFWRMREQGKPLEGYPVEMGQFWHGLPPKVDASYERHDGKIVFLKGSHYWVYEGVDMDPDYPRPLRELGLPADIDG
ALPWGQTGKTYFFKGDVYYRYDEFDHRMDKGYPKLIKENWLGVPINIDAVFRHYDGYSWNTYFIRHRRYWQFDESRGQVD
LGFPRNFGVDWMGCKEEDAKVDQPEGPGQLRAEVTMISSMTTENSSPLTLSHSSLCLCLSISFALLLNRS
>XP_003728895.1 calumenin isoform X2 [Strongylocentrotus purpuratus | PB0205
MKNSLIVCMYLALLIAVTLAKPADKGRVKEEVKLSDEEHFEGNEHNPEYDHDAFLGHEDAKTFDNLSPEESRERLGKIVE
KIDADKDGFVTEEELKDWILLQQSRYIYEDVDRQWKGHNVDGDPKITWQEYNQTTYSGLTEEELSRMQENQHMDFSTMIR
RDKKRWKVADMDNDGDLTYEEFVGFLHPEEKGHMREIVVEETMEDIDQNGDGFVDIDEYIGDMWPKSEREKGGAEPDWVQ
TEREQFFAFRDRDGDRKMDREEIGQWILPEDYDHAQAEAQHLLMESDTDNDKKLTKAEILDKYDLFVGSQATDFGEALTR
HDEF
>XP_001175598.3 serum paraoxonase/arylesterase 1-like [Strongylocentrotus purpuratus | PB0207
MWKRLILVVLVAAVVRHVFTFLKVLGLEKTVYNHKPGNCQFVRGIEHGSEDLELLSDGIVIISEGYLTFKDRVEGAPRGH
LFAYDINHHNNGATELKITGDYDVEKLHPHGITAFEDKKTKKTFLLVINHHVRFDVVDVFEFHRSSMSLSFIKSMRDPLM
TSVNNLIATGPEEFYITNEAYFLHPRMRDLENFLVMRMGSVLYCDVTGCKKATESLNNPNGIDLSRDGRYLYVSQPFTRQ
VRIYKRDPSDNTLTANEGVHVIDLGTVADNVYVDESGDVWLGCLPVAHKALTYIDTKKGLVPSQVLRVRVGPKDYELSEV
YSEDGRNITVSTSAVHHKGILLIGSLHERMMRCQVNAI
>XP_781712.2 ficolin-2 [Strongylocentrotus purpuratus | PB0208
MERRIVTVIVLLSAILCGALNEEATGEASETSAIRATVDTDGNDTINITAGEMDVDQEDSDIDNQERFVCRPHITIQTPP
VPAPISRAGQCDCNCNSSSSSRSSGDAANAQEEKQSASLARQLRELVQECRSGGGGAGGGGGLDGGWRRAGTQDETRRLA
EALVDLATVLKNFQTPGVPVPGSILSLPKDCSEVLSRGATNSGVYTIQTLDSGRPFQVYCDMDTDGGGWTVLQKRQDGSV
DFFRSYATYRRGFGSLTGEFWLGNDQIHRLTSQDEYHLRIDLEDFDHETVFAEYRVFRVADVNEDYRVTVSSYHGTAGDA
FTTHSGQPFTTKDRDNDNWSSKNCAREYHGAWWFNSCYYASLNGEYLRGISESYGTGIVWYQWHGYYYSLKRTEMKIRPA
D
>XP_802129.1 heat shock cognate 71 kDa protein [Strongylocentrotus purpuratus | PB0209
MAKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQTAMNPNNTVFDAKRLIGRNFGD
ACVKADMKHWPFDVIEEGGRPKIQIEFKGETKTFYAEEISSMVLLKMKDTAEAYLGKKVTDAVVTVPAYFNDSQRQATKD
AGVISGMNILRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSVLTIEEGIFEVKSTSGDTHLGGEDFDNRMVNH
FITEFKRKHKKDITPNKRAVRRLRTACERAKRTLSSSTQANIEIDSLFEGIDYYTSITRARFEELNSDLFRGTLEPVENA
LRDAKLDKDKIHEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSSEVQDLLLLDVAPLS
MGIETAGGVMTPLIKRNTTIPTKQTNTFTTYADNQPGVLIQVYEGERTMTKNNNLLGKFELSGIPPAPRGVPQIDVSFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEEIEKMVADAEKYKEEDDKEKDRISAKNALESYAYNMKSTMEDEKIKD
KIAEDDKTKIMDKCKEVLDWLDANQTAEKEEYEHQQKELEGICTPIITKMYQAAGGAPGGMPGGMPGGMPGGMPGGMPGG
PSGGDSGTGGGPTIEEVD
>XP_030836382.1 macrophage mannose receptor 1-like [Strongylocentrotus purpuratus | PB0210
MTRLNILALSLFAFISVSTAYVTCPDDWTRHGFSCYYFRSCDVTWDDGERECLALGGHLVSIDTRAEMAFVENLVAGEKG
PFWIGLNDKYREGQWFFTDMRRLRPELGPLWGAHEPNNNGDEDCVMFPHGADKKWNDAKCDSKYSFICEIEKFGCPDGWG
EYGDSCYHQVVTPKVNQFDAQTHCQSIHQDCSLVKIDNHDEQAFLESFFGESCADWIGLLGEVNANANSNANGVSASHHH
DHDDANGGNDGGNSGGSGEFLTRDYFFTDGQPMVHDFWKSNEPNFDKDNDRVCAIQKNTLGWNDYGCGNEMSYICELKKP
SF

>XP_030834955.1 annexin A5 isoform X1 [Strongylocentrotus purpuratus | PB0211
MSYPGYPPAGAPGYPPAGQPGYPLLLAPTRQQEGLQVTLLQGSQVTPLQPPATQQVQLHPQLEGNPMEQLQDTLLQGELV
TPCARLWRLSLCPATCTRLWCPTRRSPGIPPAGGYPAAGGYPGQQPPAAGYPGQQPPPAAGYPGQQPPPAAGYPGQQPPP
AGYGQPPAAGYPQQPPAAGYPGAAPAAYAAGGAPGYPSQPAGAQPPPPSGQQLYGAAGATVVATGLAAQYAQEKPKPMAP
PAVQEPVTSQLSRMALTDQPFETHGTVRPHHPFDAEQDASVLRKAMKGMGTDEKAIINLLATRSNAQRQTIKLQFKTMYG
KDLIHDLKSELSGKLEDLILAMFVPGPQYDAYAINKAIKGLGTDEEILIEILCTRTNKEIHEINEEYKKQFRTTMEKDCI
GDTSGHFKRLLVSMCQGNRDESSTVDMAKAQAEANALYQAGEKKWGTDESEFNRILATRNFAQLRATFKEYTRIAQRDLL
NSIEREFSGNIKNGLKTIVQCTQSRPSYFADRAYRAMKGAGTDDDTLIRVIVTRSEIDLVEIKKAFLEKYHKTLGKMVSG
DTSGDYKKLLVALIGQD
>XP_030854074.1 uncharacterized protein LOC115929361 isoform X2 [Strongylocentrotus purpuratus | PB0212
MEFVAEAHVPEGSTTPSKLLLQPRGVPVPAEDYWVIYTDYVDHALVYSCSQRNEDGTCPEDRARVWFLGRAGTLSVDARH
HMESLLSGLCVEVSRMQDISTGCDAELGVPTSVEAMPHAHGGMVSSTCLVNDIHTMANFDKNQYTGTWYVISHLQGDIYP
YHRISHYTLDEQNSFRMLTHRITSPGECSTAWKFEGQAYNPDTSETTSKLVLKPFGMPVYGEDYWVIYTDYTDHALIYSC
RETNEDGTCKAEASHAWMMSRDPTLTPAARSHMEMLLTEMCVDVSRLVDTPHECDELLGPESLIDQGRIIAPLHVFLWRN
VLKVLSL
>XP_030843473.1 gremlin-1-like [Strongylocentrotus purpuratus | PB0213
MIAAVLWISSLLACALMTSSVPHADVASRVFHHRVSSQGSNDLPTDTQKRHDQDHVTMSPQSDSSDTHYGAHLIDRTVLF
PHDTTWCVARPISQVIESPGCTARTIPNKMCAGQCYSFTVPKIFPHDIRSQFKSCDCCQPSRVTWVTIPLSCNAVDGDTV
LHKHVEVVEECECKPCSFYTSTSSWSTESTTTNDTEYSDEQSSYVESPSAP
>XP_781712.2 ficolin-2 [Strongylocentrotus purpuratus | PB0214
MERRIVTVIVLLSAILCGALNEEATGEASETSAIRATVDTDGNDTINITAGEMDVDQEDSDIDNQERFVCRPHITIQTPP
VPAPISRAGQCDCNCNSSSSSRSSGDAANAQEEKQSASLARQLRELVQECRSGGGGAGGGGGLDGGWRRAGTQDETRRLA
EALVDLATVLKNFQTPGVPVPGSILSLPKDCSEVLSRGATNSGVYTIQTLDSGRPFQVYCDMDTDGGGWTVLQKRQDGSV
DFFRSYATYRRGFGSLTGEFWLGNDQIHRLTSQDEYHLRIDLEDFDHETVFAEYRVFRVADVNEDYRVTVSSYHGTAGDA
FTTHSGQPFTTKDRDNDNWSSKNCAREYHGAWWFNSCYYASLNGEYLRGISESYGTGIVWYQWHGYYYSLKRTEMKIRPA
D
>XP_011666177.1 leukocyte elastase inhibitor [Strongylocentrotus purpuratus | PB0215
MSEYIRNMAFYKQQDISEQLVQLSSANTRFALDLYQTFQDERRGTNLFFSPLSISTALAMTQLGACGDTATQIADVFRFN
QVDQDQLHGTFKELNNLLYQTNSGYKLHAANRLYGKSGYNFVQSFLEGTASYYGAAIEAVDNFAAPTATHSINDWVSKQT
EDKITNLIPPGILNDLTRLVLVNAIYFKGNWESKFRAENTTQETFKVLDERKKVPVSLMIQKGKFALAVDKTNDCLVLEM
PYQGRNLSLLIALPVKDDGLGNLQTKLSADILRSWDAGLKSRQVNVLLPKFKLEAEFQLKEVLKRMGMPDAFNDGKANFE
GISGDRELYISAVIHKAFVDINEEGSEAAAATAVAVKLGCARPREPEKPTLFRADHPFIFMIRHRPTKSVLFMGRMMDPS
>XP_011667363.2 secreted frizzled-related protein 3-like [Strongylocentrotus purpuratus | PB0220
MNCGNFLLRAMHSSCTLRWLSMNRSVFIPFTLFTALSAMSMNGGRPECQLVQLPMCESMPYNLTRMPNLLHHSTQENAKL
AIEQFLPLVNTNCSGNLTFFLCAMYVPICTMGFMEEPVPPCKSVCQNVRAGCEPIMIEHNVSWPVYLSCDQLPEYTSGVC
ITRDAIVDSGPTMDHFQPTPTVPEVPPGNCDVCQYDYELSRDLFFEKEYEFVIRARVEGFHSGTRRGEMYIRVIIHHVVQ
FSEIHIPVGEVQLWVNNYCACPMMTSGEEYMIMCYQDIINGRLLLENDCLVIPWHSRYVKRVKKWGQKLLHDQRDRDSSD
SRSNRRNRDIYYLYG
>XP_011677219.2 follistatin isoform X2 [Strongylocentrotus purpuratus | PB0221
MKRYCQLVFIISSLWTFSGLQSADGGVCWSSPPNGNPCSQLIKLHLSKEECCHNQGPTISWSREDLDLGKLMRTLLTSRI
ALSECIPCRETCEEMQCRDDQKCIIDHNNRTRCVCQPHCENIEYEGAVCGTDNYEYGSVCELLTERCIQSSEVEVAYYGQ
CQDSCDGVTCPRGRRCVEDQAGRPHCVLCWAVCRYHFRDTQYVCGRDQITYESLCHLRLSSCLIGKAVGIAHEGRCENFT
SCSALSCVRGNQCVMDPIEEEPRCVMCNITCPERWLSGPVCGSDGVTYPTQCHLHNHMCANDTYVEVDRRSPCNVETANS
GEESGSIDHTTFLDIVEPIAVPLDQVNNTGRSLRQRSNPIEQVNNEVEDVTTEIYDIETTIVTEIEDVEDPQVSTDGDGR
DGEGRSNKEEAVVERDGEA
>XP_011676138.2 alpha-2-macroglobulin-like protein 1 [Strongylocentrotus purpuratus | PB0222
MRLIVSLLIFTIAVMVRGQEDGDELRVALTLPPIAEEVTQLPEPTTTPALPLSPEELREEDFNKEISYLFLIPKLFYVQT
KERICLLVTKSDGLLDYRVSLQKINAGQYEEYWSPGEQEAKQGENCFEFDVPTIESGSNQRQKVRLQLRRKGAEDLNEDG
YEVTKERFVRIQAQGGSKTYVQTDKPIYQPGQTVRFRALTLNSELKTVTEPFDSVIVESQSRQRVNQWTDVKGEEGLIEL
EHELPDELPDGITKLTYYIKVLRGTESVTQTFTVEEYVLPRFEVEVITPPYILITDPTCTVKVCGTYTYGKPVQGSVQAN
ITADGGRYDYRTRTRSSREVLPFAIPSTDADGCAVINVNLTRLELTSRKFYIYGNLQVSARFTETATGETLTDKSTSRMS
SYTLTMRAINKNNFFKPALPYFGAVEVTNPDGAPKPGESIIVRCNALDSPVEATSNDQGFAVFTLPLQGIYEGFDSGNSL
SCNVTAKDFQENIPYDPDVWTLNRPITYFSLSPMYSPTDNYLEVEAVIQFGNPIQVGGSVSISVHMTKDCTDGPKILAVS
RGNILQDFEYKASRQESANGIIYDVTFVLTPLMTPFLDLLVFGILDDGEMIADSLEIESKAVFENEVHIQVADGQDATLE
PGARTSIEIIASPGSLCAVGVVDKSVHILGGNNQMKTSDVVSFLNTFQLSSGDNDNPRCQDHEDEPINIDDGGVGGPIPF
IPRPVFEVALEPQVLARKKRQFGFSPYRRDPYPLYSDVTREFEQLGLVRISNLKVETSPCQTPEPYPYYFRNEAFAFAAQ
ADFAQALSVSAVSAGPAIRKYFPETWLWYMQRPEESPTVTVPDTITEWVGSGFCISSTTGFGISEPFSVTAFKQFFADYN
LPYSVIRGEELELQINIFNYLEKCLPVKVTLTASSKFEIKEESNSKYTCVCSSSEPTQVTFNVRPTALGDVDLETTVIVA
YDQTVCRGKPVETGVTHSDGLSKPILVEPEGEEVEESLSLYFCPKEEEDGTFRHTFEISVPVEYVADSGRVTIFMSGDIL
GNSLANIDRLLRIPSGCGEQNMIGFVPNIYALQYLQATEQADQSQVNKALSNMRKGYQKQLNYRRSRGSYSAFGNRDPAG
SAWLTAYVIRSFAQASQFISIDTKDLDVSINWLYNTLGQEENGCFRSRGRVIHKEMQGGVNDEVTLTAFIVVSLLEAQQP
LETQAIQDALSCITNSIGSLEDTYTAALIAYALSIAKDTNVVQVLEYLESVDKNEIGVRYWVSSRTQTPGSRRYGRGATA
SSLSIEMTAYVLLTYINVYGHDAIARGSAISKWLVSQQGPHGGFKSSQDTVVAIHALAEYARLVFGGESNLGIAFSYKEH
CLWNSIFVIHDGNRLVLQRADLDQLPKAIAVIATGEGCALLQVIIRYNIHPALPPAPAFEIIYNVGPTTQQDACQGSFNL
NVCVRYLGDDGFSNMAMVEVKLVTGLFLSKIPLIC

>XP_030834113.1 amyloid-like protein 1 isoform X1 [Strongylocentrotus purpuratus | PB0223
MSIKQHNNGDYDCIKFRPSNQLLSFFIFLQALAAGAFDPSSSRFELRVAVRKGYFNKYADILSGQWLTDTSAEFTADATE
VLNYCKTKYPDTEINNIVDSSQPILIDQWCPVNGDACTSSAKVTYYRCLVGPFESDALMVYNVCKFYHKHDENTCREPEY
WKGVADEDCRGKKMGINSTGMLLPCQTDKFKGVEYTCCPPPTYRPMTAGEEETEVEEEEEEAEAEAAAAGGETQAQVQEE
LPVQAPAPAPERDNVVAKPQITSNILDDPYFSEQGLAGRVEKKEYSNAKGRLSSNQKAKMARVMQQWQEAQEHYETLKAK
DPEAAEQMRKEMTQRFEQTIGTMETENAEETEELREAHQVHIAVSLREKINASYEAYRFTVDVPKPKSKKILHSLRRYLH
AIQKARQHYIIHYKHLRKTDPMKADQHKRFTLNKLKTLDIEVAQSVDLLQNLPDLYAELKPKVDALLDSTHDTPEDAALI
RATEEEEEVEEEEVMIAQAKVTEAPPAPQRTELEPVAEITEPEVADEVISQAEEEELEEVEEFLEEDTEAPTVSRSFETK
PSTLAKTSPAQTKPSPSQTKPRTSTATQTEPEPPTPSRDTEPEIEQETEIQVPAENVQIVAVKPIESYLDEELTAPLDSD
VVKPQTLIIAQKPKAKVEKSAAAARMEKQRLVGRQDVNSIDNSVTKKRMSLRYEPMMAFGLACGVLAVATVLVIAVLIVR
RKTRRTPVNSGFTEIDPNLTVEQRHIVAMQQNGYENPTYKYFDMQ
>XP_030829532.1 advillin isoform X3 [Strongylocentrotus purpuratus | PB0224
MSKVDPAFSGVGKKEGLKIWRIENLKVVAIPDKSYGQFHKGDSYICLKTNKKGNGFSWNIHFWLGTETSQDEAGVAAYKT
VELDDSLGGGPVQFREVESSESAEFMSYFPKGIRYLEGGIKSGFKKVDKDKFEKKMYIVKGKRNIRVNQVPCKWESLNNG
DVFIFDLGQHIVVWNGPQSSRTERMQGTQAAKGIRDDERGGKARILFVDDDKLDAETLKVCEAKVALGPRGGIKPQAAKD
DDERFSRKQAAQTRLYKVSDESGSLVVTEICSAPLDQTMLNSNDCFIVDQGHCGIFVWKGKGSTKQERKSAFSNAQGFIK
AKQYPENTPVTVINENSETIAFKAIFKGWKDPGDTKGLGKTHTTGNIAHVKKEKFDASSLHKIKTSDIDSNPNMASRTGM
YDDGSGKIEVFRIENFEAVKQSNELQGQFFGGDSYIVKYTYKQGGRERYIIYYWLGLTSSKDEQGAAAILTTKMDDKLNG
AAVQIRVVQGKEPQHFLQLFKGKMIIHLAGRSSGFKNQQAEDKKGNRVRMYQVKGTNEYNTRAVEVEVSAKSLNANDIFV
IKGPKQLYIWAGKGGSGDERELGKKVAKVLEPKSAYTLVPEEKEPAEFWEAIGGKQEYASSPRLQEETPAHGPRLFQCSN
ASGNFRVEEINNYTQQDLIQDDVMLLDAYNELYIWVGAGANAEEKKQILGTAKEYLMTDPSGRDPDSTQLIQVKQGFEPV
PFTGWFMAWDNKYFQSMQTEDQMRQELAKQNAVVVIDLKQIKKAAEEQEDSFENCPKFTLAELQAKEVPEGVVSGKKEKH
LSKEDFQKLFGMPYEKYATIPKWKQDNLKKKAGVY
>XP_030855129.1 calpain-9-like isoform X2 [Strongylocentrotus purpuratus | PB0225
MFKQKVIKQGKEYDSIVRQCRQSGAKFEDPLFPACVESLFFEQKPPQPFVWKRPSEIVQNPQLFVGGASRFDVAQGQLGD
CWFLAATAGLSLDDHLLKKVIPPDQNFDLGVVKFNFWQYGKWVTVVIDDQLPTYNNELVFVHSKEKNEFWSALLEKAYAK
LHGSYECLKGGNVIEAMEDFTGGVSESIDLNQNPPKGLFKILKSSYDRDSQLGCSINAKPGVTEAKLPSGLIAGHAYTIT
DVKKVNVKGRDVRLIRIRNPWGAVEWNGRWSDNAREWDDINQRERKNLGLVSGDDGEFWMEFSDFKRNFERVDMCHLSAE
AMTGKGKRKWQAIVNDGKWQKGATAGGCRNFPDSFWINPQFSLILEEEDDKDDVGDEEDEDPGQDKPGSTFLVALMQKNR
RAQRKMGVDNLTCGFAIYQTDGNFDASVGLPKDHFLYNASTARSPSFTNTREVSGRFKLPPGHYVIVPSTFEPGQEGDFL
LRIFSMKLSKGVSIDEESGMVDVPKQPPPQDDAQTQRFREFFKKLTGPDMEVDAWELQEILNAALRKELQGGGFSLESCK
SMVALTDDDRSGKLGFEEFRELWQNISAWKAVFKKYDQDKSGSFNGYEMKGALRSLGFKLSNESFSALILRYADKKGTVS
FDSFIAAAIKLKYMFTSFAAKSRGGNASFGLDEFLTMNIYS
>XP_030855129.1 calpain-9-like isoform X2 [Strongylocentrotus purpuratus | PB0226
MFKQKVIKQGKEYDSIVRQCRQSGAKFEDPLFPACVESLFFEQKPPQPFVWKRPSEIVQNPQLFVGGASRFDVAQGQLGD
CWFLAATAGLSLDDHLLKKVIPPDQNFDLGVVKFNFWQYGKWVTVVIDDQLPTYNNELVFVHSKEKNEFWSALLEKAYAK
LHGSYECLKGGNVIEAMEDFTGGVSESIDLNQNPPKGLFKILKSSYDRDSQLGCSINAKPGVTEAKLPSGLIAGHAYTIT
DVKKVNVKGRDVRLIRIRNPWGAVEWNGRWSDNAREWDDINQRERKNLGLVSGDDGEFWMEFSDFKRNFERVDMCHLSAE
AMTGKGKRKWQAIVNDGKWQKGATAGGCRNFPDSFWINPQFSLILEEEDDKDDVGDEEDEDPGQDKPGSTFLVALMQKNR
RAQRKMGVDNLTCGFAIYQTDGNFDASVGLPKDHFLYNASTARSPSFTNTREVSGRFKLPPGHYVIVPSTFEPGQEGDFL
LRIFSMKLSKGVSIDEESGMVDVPKQPPPQDDAQTQRFREFFKKLTGPDMEVDAWELQEILNAALRKELQGGGFSLESCK
SMVALTDDDRSGKLGFEEFRELWQNISAWKAVFKKYDQDKSGSFNGYEMKGALRSLGFKLSNESFSALILRYADKKGTVS
FDSFIAAAIKLKYMFTSFAAKSRGGNASFGLDEFLTMNIYS
>XP_030855129.1 calpain-9-like isoform X2 [Strongylocentrotus purpuratus | PB0227
MFKQKVIKQGKEYDSIVRQCRQSGAKFEDPLFPACVESLFFEQKPPQPFVWKRPSEIVQNPQLFVGGASRFDVAQGQLGD
CWFLAATAGLSLDDHLLKKVIPPDQNFDLGVVKFNFWQYGKWVTVVIDDQLPTYNNELVFVHSKEKNEFWSALLEKAYAK
LHGSYECLKGGNVIEAMEDFTGGVSESIDLNQNPPKGLFKILKSSYDRDSQLGCSINAKPGVTEAKLPSGLIAGHAYTIT
DVKKVNVKGRDVRLIRIRNPWGAVEWNGRWSDNAREWDDINQRERKNLGLVSGDDGEFWMEFSDFKRNFERVDMCHLSAE
AMTGKGKRKWQAIVNDGKWQKGATAGGCRNFPDSFWINPQFSLILEEEDDKDDVGDEEDEDPGQDKPGSTFLVALMQKNR
RAQRKMGVDNLTCGFAIYQTDGNFDASVGLPKDHFLYNASTARSPSFTNTREVSGRFKLPPGHYVIVPSTFEPGQEGDFL
LRIFSMKLSKGVSIDEESGMVDVPKQPPPQDDAQTQRFREFFKKLTGPDMEVDAWELQEILNAALRKELQGGGFSLESCK
SMVALTDDDRSGKLGFEEFRELWQNISAWKAVFKKYDQDKSGSFNGYEMKGALRSLGFKLSNESFSALILRYADKKGTVS
FDSFIAAAIKLKYMFTSFAAKSRGGNASFGLDEFLTMNIYS
>XP_030830245.1 collagen alpha-1(I) chain isoform X3 [Strongylocentrotus purpuratus | PB0229
MLLRPYSGSRGTVFGVTDPYHQTIILSVNITSMSIEQMRISLILTNIDYTSESTEVAAFLVPSFTNHWTQLALSIRDNQV
TLFLDCQELGMQFFDKNQGWHIRIPQMAPLFIGHLGTVGERVQYRGDIQQIIITNSADSAEEHCPIGEISGSGSMALRES
AGEDWAFVFSGSGDEPTSMPEMPITYFTQYDAETPSTPANNVRLPASVQPPLEQVATILPKAPPTTPTLQATPSSQPAVV
VPPGDSMKGQKGEEGWPGVNGIHGNPGVPGPRGVGGETGPEGPEGPMGPKGEKGDLGDAGPVGPLGEEGFPGVAGPPGDP
GVKGEEGDQGMTGATGAKGEPGVGVPGLPGVAPTLSSEYMMRLGGEKGDPGRDGYPGVPGVQGPMGIPGVDGIGVPGPKG
DKGEVGLGLPGSQGKPGKEGPKGETGQRGLPGPSSLESFIEGSGLEMFVGPPGQPGSPGRPGVMGPHGPRGESGLDGIPG
LDGVPGQPGPAGRDGEPGPKGEPGALTEEEILDEIANLTAEFEMEGLSGMDGFNGSRGPPGVPGAVGPKGDSGMDGNPGM
KGERGSSGLPGLEGPEGMKGGPGQNGIPGVPGIAGIPGESGQNGARGAPGPAGPPGPPGPSPLLPPGFPWTNMALNQDQE
GSADGSGVWSGTVPPYLMGSPGVQGPPGPEGMQGEPGLVGEPGIPGEPAIPGMPGLTGERGERGLPGPRGMEGETGMDGA
AGQKGDTGDPGVPGQPGADGFPGPRGVGVQGPPGDRGLPGPRGIQGLKGDVGEQGPACEIPPEILALSEHFAGVGSGDIG
GGMMTRAPQELTSTKGEKGDIGFDGVPGMDGQQGAKGYPGPRGPGGVVGPKGNNGTQGEKGDVGAVGYAGPRGVKGDKGD
MFLPTEEEMLMLKGDGGDTGRRGKKGLKGQFGIPGRPGRVGKTGPEGQTGPEGPVGPQGPPGPSGGGEGTCECDPAAFPP
AFFPPGEKGSMGAPGSPGPMGPDGVPGAPGLPGVQGLRGLQGYAGEPGIEGLEGRPGAQGVPGVPGIDGARGEKGDPGDF
FVNDEVFIGPPGEQGLPGRDGQPGQSIKGDTGEPGHGAEGMPGRDGRDGSQGPPGPPGMPGHPGEPAYYTGDGNGERGPK
GEPGEPGREGQSGAPGFDGRPGSRGPRGPQGPTGYGEQGPPGEPGTPGEPGRGSIGHLGGGDYVGMARFATIQDMLDGMR
DLEVGTLAFIIRVQELYIRVETGMQQVLLGATFTLPPTSEPRPQPRPQPRPQPSITSRTTTTTLIPTTTLAPFVDPTEPP
QIPGPGLTDRTEEPILPGPEIPVSDQPMLYMYALNTPQEGYMIGGISGADFKCWKQAKAAGLKGTYRAFLSSPLQDIRTI
VRKQDKGLPIANGKQEVLFNSWDDIFSTENEAPFHDSFHIYSFDGKDVMTDETWPDKYMWHGSYANGERMAESFCEAWRA
QNHFARGQASPLSDHKLLGQDEFPCNNAFAVLCVQTARPNARK
>XP_030855716.1 alpha-2 collagen isoform X3 [Strongylocentrotus purpuratus | PB0230
MYSFVDQIRQHRQTLLLILATITVFAVVCQGQESSFSLSISSGEPLLPCVYRGQPYLHAESWSVDECTICSCDNATTTCV
IESCQPAFCVEPIKPEGECCFLCPFNVKVKKVAPVITSTGSISEGRENRLTLRVPIKFQEAQDTTGVAGEGLWRLSAWAS
PNMDGRGQRFGYQSQTLTEAQQAKHYKKKDSFNFQDVDFRLTDPMAQCTDMMYICTRLDRGESPRTKGGLDYEFSGFPDD
NALTGCTTAPECKGVFAEDLEWTLEPVEPVFPGEESSVSLDSTVTFRDGNRELVGSGLWRQGLFGSRNRDGSGERFNYKR
QTLDRPQASTTLIADSPLEVQDAITDFEIGTVGCNDFNYLCLEFTGGDNPNPDYFFRVIDAMDNSAEANTLVKCKEQECL
SKAIFTDLEADLGNQIIYENKRNPLSVDLTGVTHDDATNVRGDQLWKMAVYGSRRADGSGPKAGLEEQILDPTEASTTLL
DEENLMMNNVNFEFDMTGIRCEDAEWVCFDLDKNNRASVNYIFEARPDESVITECIDMRDRCKGVTAIDIDWEADVGDAP
FGQPSPLTLTADINFDPLSPDVNGQGLWQLGVFAATRPDGDGPRRDEISQTLDPFNGAKPLEEGGPLEFDNVLTNFPIDE
LGCDDYRYLCVEFKQGVAPTPGYKFETQAGTDSIISCREQPCRGVEVSELHSQPTETLSDLILYEGKDTNPIQYNSVATT
TPDSGTVRGVDLWTLSQWGSERANGNGPQQNYQEEVLSGYHAALPVMAAGDTLDFVPLATNFDMTGLRCPQVKYICNELS
KDPRSRPDFEFTAVPDETVLRSCFEVPDGACKGVVFTDLDWDMSHGPVSADGPDDVRFNVDVSTLPESGGADGDGLWRIG
VFGAQNPQGTGPRLDYKRQILTRGQSSTPAEGEGMPLELNALETEFDLSQIGCDSEYRWLCLEFAKGLRASPDFEFEING
GGDVIISCKEQPCRRPVMINDVETNPLGNVRVNEGTRNNRILYEMTALTDPSSGKAQGKNLWEMSTFGSSFPDGRGRRFN
PQTAYTFTQYQKDKSAFPGENIRYGAVDTNMDMTGLTCNDVRYFCSELRKGDYPSPDFEMIANPTEDVLTDCFELNCEGV
LIDNTRLSLNSDSELSDGPNDLSFDFTVNSNPTGGDAAGNNLWRLETFTSNNNDGSGRRDILRTQTLDPADASYDLDAGN
TMVFRNLEALVDSADVNCEEDYYLCAELSKHVAASSGFSMRATRENALTSCRLIRCAKAAPPPVQGRPGPKGAKGEPFDI
PPGMVGPPGRPGLAGSVGYHGRRGPNGLSGPAGQRGEDGRDGNSGNRGTPGPPGPPGPPGEMTAAAQQSKGPAYTAPIYN
TAPGRPGSAGYSGHRGARGPQGLTGPMGPQGSAGPMGMSGPRGARGEDGEDGNDGQNGRQGEIGLVGISGRPGLGGMHGM
SGNPGHKGWGGRHGAPGAAGERGEAGEGGNMGASGPVGAVGNPGQRGPSGSRGGAGSKGPMGDSGERGSNGEQGPTGNMG
PLGPSGLPGANGATGDSGMQGGQGSSGPVGLVGESGSRGKSGSAGAPGIPGSSGDSGIIGEMGIQGEVGGPGRNGAPGLQ
GSIGPVGIGGERGDAGLPGYMGLTGSRGPAGPSGARGIGGEPGPAGNSGSEGETGSTGPSGPRGPMGELGMGGGPGMLGA
PGNSGFMGDQGESGEQGSPGEPGSRGTNGEPGTPGQTGPNGAPGEDGLAGNDGKTGATGTPGRSGPPGANGDRGGMGPPG
AQGPPGIGGETGFNGNTGIQGTPGTRGEAGVDGEPGAAGQSGLPGSPGNRGDSGTQGPVGIGGSQGAPGQPGLTGTRGAR
GNNGPSGPRGGLGVSGDAGEQGLRGAAGLQGASGIVGERGTEGRSGRNGEVGPTGIGGSMGQPGLRGLPGPPGLRGGVGG
LGEMGTQGDRGPSGPSGPSGRTGEAGGLGPLGPMGVTGQRGDNGNPGDPGPNGPSGLKGTRGAGGEKGSMGSRGIPGNPG
PGGAPGERGPSGLNGEKGEAGPFGSQGRPGRSGPQGNMGARGERGETGNQGALGPSGSSGMNGPPGVVGEPGPTGPVGPT
GRSGEDGRMGSRGPQGNQGVRGPPGVQGLMGSQGSSGEDGRDGHVGPPGPMGAMGQAGNLGNLGSHGFMGPPGPAGPQGR
PGVSGEAGRDGANGERGEGGRMGPSGPVGVRGMPGSDGRDGKDGPAGPVGLVGGRGDTGAKGNNGMNGLMGPRGPSGIMG
AQGERGNRGKQGAQGSVGNVGESGGTGPMGSMGPAGARGEVGSQGATGHKGQNGMPGMPGMMGVAGEPGNNGEGGPQGIR
GIPGVVGEGGKSGRGGPRGPPGLRGGNGGRGERGNLGPSGPPGPAGPPGPPGEVSMAAMPRMPQQQQSKGPSQYSHYYRD
EIPKTVEQLDRTQFQIYLAKFESEILSLIEPLGSRDQPIRSCKDLFKCYPEAEDGNYWIDSNEGSVKDAFLAHCVKRGES
GSPETCITPRVDEISRARWYEGASGSRYITEMGLEKFSYEASEVQLTFLRLLSTKAHQNVTYHCKNSVAVRDRQTGSTEQ
ALRLMTTSDVELSLDAPSQEQYEVIEDGCQERSAEWSQTVINYSTRRNTRLPIVDVAPSDIGGEGQEFGITLGPVCFS
>XP_787649.4 fibulin-1 isoform X2 [Strongylocentrotus purpuratus | PB0231
MKVYISLITLLVCFSFCHASLIDVMPDCCERGASFAGLGRTCDDLEAIPDIAPGDHGICMVIMKSCCANSLGPVLCERAL
NHRMNVGSCQTMNNDTCFSAGRECCDCCELGINAFHDGIECESMRTGTSCDRAFAYCCKAAASSFDENECSLQTSHRLCT
ERCVNLIDNYVCECHPGNHLLEDNITCVADGDTRPPPRYLACSQAPCQHECRQVGREYECYCRTGYELLSDGYTCEDVDE
CAVTDSLACNYAERCLNTIGSFNCISDVVCRSGLKYDPVNQYCVDIDECAERTDTCDERSICENRYASYTCQHASCPTGY
YYDRTVSQCNDIDECARGTHECLDGARCDNLPGSFHCTRIVPCGTGYTINGVTQQCVDVDECSQQSHDCEINELCINIRG
SYDCQSCPRGFKTNGNVNRCTQDINECQEGTFDCREGTRCENNVGSYTCISICMTGFEYNRILRACMDVDECRRGLANCA
TYEICQNTNGSFSCGCRQGFRQNNYGQCVDIDECREGLSECKPNQRCYNLQGQYQCRNMCRNGFRFNNFNSACEDIDECA
EGLDVCQNNQRCINQEGGYVCQCPAGHQANRDRATCEDIDECSLGLCRGTCENLPGSYVCTCPAGYALMENNVTCKDLDE
CSTGTDTCIQDEVCFNTRGGHKCESVVCPEYYQVRTSNDNIQCVKTCPRTGNAPDCPPGNLNSTISHTFVALPSIPFLRQ
PIRLLTIGLPNYRSAYGGSSQTYFRSISGNEDQYFVITRLFPRGLPTGYVSLQKPISGPFETVLHLEIVTEVRNPVTRRT
EVTATSYLMIHIDVGEQSY
>NP_999642.1 alphaP integrin precursor [Strongylocentrotus purpuratus | PB0234
MARFLLLSFCTTLVLLDSTVAFNFDLRAPVKFDGPQGSLFGFSVAQHRDQNTDWVLIGAPEAPTTQPGVTNGGAVYKCPV
TPLSGSGPCEQVPFDTTGNTEVLDKSNQWFGATLASSGPDGRILACAPRLVWLQTSTISPTDKEREPTGTCFVGHSDFTN
FVNYSPCQSTDRDLFGFDKITHCQAGFSAQIPSDNSTLVMGAPGSYYLQGQIFAQSLSTLSDVSNTPEQAVAFDNSYRGY
SLALGDFNGDGLEDYVVGTPRGESLRGLVAIFDQSLVEIITPVVGEQIVSYFGYSVASVDVNGDGLDDLLVGAPMFTNRE
PATEKWEAGRVYVYLQNADHSLGAPQMLTGKKIRARFGFPITSIGDSNQDGFNDVAIGAPYDGEDNSGVVYIYHGSAEGL
RLTESQVLTPSELGFSDITTFGFSVDGGQDMDQNDYPDLVVGAESADAAILVRTRPVVLLEAELTIEPIGINLDNKTYEL
PDGTMVTSFVAMACFTYTGNHLPARIGISYTLTVDSSITSGRRALLEVNELSQVTKNRNLDVGMKFCDPLRAYVVNTIQD
KLTPIAVDLQYELTDESILLPYEILPIINKEAVSSQTKQVSIQNNCVNNICIPEIGITVTPNLPNIVIGQAQELTLVVSI
NNRGEDAFQSTLAVYYPEGLQYVRLERRANMDFSVTCTEDSALRMITCDTGNPLVGKYNLEFGLTLSTLQVSGDKDNIEF
YLVAGSENNEDPNTLDNNELNVTVAVIVDATLKLLSASYPEIVTYRVPEDNIVPEFPTKNASEADIGMEVVHLYEVRNTG
SSNAAEVTLNIRWPEKDENGDYLFYLLGIMTDEGVTCQISQGQANPLGVKLEASTKEQLSNSTTQVSGRRKREGEYAEAL
AQAEPIFCTPESCVLINCTIDEIKATKSKVVRILGRFWERTFQKAVSEAVPVIQVTLASTATATVRSIPYNIPLPMEFTD
STKASTLITAEELVLPPVSIAWWIIVVSVLGGIILLLIIILGLWKCGFFERKKPGEDQKEYEPVAVTEKDGPPEVYDAPD
RSSANSNTFLVCSY
>XP_030846762.1 integrin alpha-V [Strongylocentrotus purpuratus | PB0235
MECKMFSAHRSYQVYERTREPFLAMLTIWRTSLILMVMGWFIVSSDAFNTDVSSPIIRHGPEGSYFGYSLTMHREMGENM
LLVGAPRAQTDQPGVDAGGALYKCPLTSLSTYEDCHQVTIDPEGNVMENGEEMTNKSGQMFGATVHSGGADSPVVVCRPL
YTWLGYPPSSPLTMRNPVGGCIITKRNFTEIHEYTPCLDPDSTKLLSCQLGLSAAVSEDEILMGAVGNFKGKGQVHVAAL
YESLGTYSSREPKNLQESDYKGYSVSFGDFDGDTLNEYIVGAPRAALNRGMVSILDVSLSEIIVMQGSQMGEYFGHSATG
SDLTGDGFDELIVTAPMYSNVDDKRHDVGRVYIYQNNGDGTFEAPQILTGRQAGGRFGFSIAPLGDVNQDGFKDLAIGAP
HDGETGLGRVYIFHSSGRQGLYQSATQVLDPLTLGLTLPTFGFSLSSGMDMDNNQYPDLVVGMYKASTVALFRSRPVVDV
SAHVSVDLKGIRLKERNYRLPSGALVLGFNVTLCLSFDGINIPQEIFLDYDLIADAKLPVSQRCYFELLDQPDSAGIRDR
VNISTGSEICLSHVAYIPNSIQDKLTPITMRADYSLVIADQVNSTLFRPADIQPILNKNIPASTSLTVPILRNCQNLTCV
PDLRLAVTKNVEKLFVGDRKNIIMIITITNQGEDAYQSRLKIHTPPELLFKKAEQLRLIHDFIASCSNDVQLSLVTCTVG
NPLPAGAELKLRVEFENVNLSGQVDLLTFSMQVQSVEAERESTRRDNLMDVLIPVEIVASMELIGVSSPQEVVFRPEHYP
LDRTINSYDDVGPEISHYFSLINKGPSHIGPTIVHIEWPLFTNNGTLLLLLTRASMNNGQMCTVNAYVNPAKLPVRGKFD
WRSAGPMTRNCLVKQRSLQ
>XP_030846197.1 integrin beta G subunit [Strongylocentrotus purpuratus | PB0236
MAWKCLLVLTIAFSAGQLYRTYAQTSSSACSDAKTCGECISLDSSCGWCTLLNYTDDTGNPQCDLASSLSQRGCSQIVDP
DSTMVVRMDIPLSNAGSTPQGQAVQVRPQQVDLKLRRGKPVVMTLQVRQAEDYPVDLYYVMDLSKSMEDDLSKLMDLGDI
LASEMKNITSNFRLGFGSFVDKTVMPYVSTVPEKLIAPCTGCEAPYGFKNVLPLNENTNLFSETVMNQRASGNLDAPEGG
MDALMQITVCGNQIGWRENARHLVIYTTDSSFHYAGDGKLGGIITPNDGQCYLDPISQNYTMSHYLDYPSISHLNAKMRE
NSVIPIFAVIQKEFEIYNNLTQYIEGATAGILAQDSNNIVQLVKDNYSKITSRVEVVDDAPENVTIDYVAHCPGGQVTPG
SQVCEGLQLGDTVNFTLTITATGCPPNKYQQFTVRPIGFNEELKVNVEFACDCDCEAQKVENSQVCSGGNGTLECGSCIC
NPGHYGRYCECSSDDPTLEDNDAPCISPNTSIVCSGRGSCVCGNCICFPRPNPSEVVSGTFCECDNFNCDRYLGELCGGS
DRGQCVCDEYTRRSQCRCRSGYSGDACECSTRVDTCMTGDTICNGEGVCICGECKCNAGSSYRGALCQDCPTCSGQCSRN
EECVQCKAFGTGLSKADCDKCPFPVIMVDNLEIPTGSERCLAEDEDDCSIIFTYAKSANGSLILYVQKEKVCFEPVDIMH
VIIGIVVGIIIVGLALLLVWRLLVYVQDSREFASFEKERAGTHWGQNENPIYKPSTSTFKNPTYQK
>XP_030848715.1 plastin-3 [Strongylocentrotus purpuratus | PB0237
MALTDEAEIREYFNEMDLNRDGFLTANELQEILEQCNEKVPGFKIRQYIAEYDTDKNGALTYDEFIKLYHDIKKGKASAG
FLTAVKSRVGIQSEKGTSDVSATGTTHSYSVEETAAFTAFINDDSKFQNDPILGPRLPIQGEDGLFNAVADGILLCKMVN
KSSPNTIDERAISTGKLNKFTQLENLTLALNSARSIGCSVVNIDPLDLQQGTKHLVLGLVWQIIRIGLFANIDLHNVPGL
MNLLHDGETLEDLQKLTPEELLIRWVNYHLEQGGSPRRIKNFSEDIHDSEVYSILIKQIAPADKKGELVEVVLGKDLEKR
AGTVLQNADTLGCKAFVTPKEIVKGNSKLNMAFVANLFNHHPALDPPEDMEFEDVEETREEKTYRNWMNSLSVSPYVHHL
YSDLSNGLVLLQLINNVNPGIVNWDKVNQGATLKKMGGNMKKIENCNYAVDLGREMKFSLVGIGGQDIRDGNQTLTLAIV
WQLLRAYTLGILQKINDSDKPLTDPQIVEWANNKLEEAGKKSKISHFKDPSISDSKVILDLMDAIKPNCVNFDLYIDPRE
DPSTSEETKLKNAQYAITIARKSGAMVYALPEDIVEVNPKMVMTIFACIMALDQVLLAQNS
>XP_798048.3 plasminogen-like [Strongylocentrotus purpuratus | PB0238
MLDTTKYEETTISTTPACQEDPTGVNYRGNLSRTIQDQTCQAWTSQDPYQHTKTPANYPNAGLDNNYCRNLDMRFTAWCF
TTNPGTRWDFCAVGYLDPKCQATPACQEDPTGVNYRGNLSQTINNHTCQAWTSQDPHEHANTPADFPNAGLDENYCRNPN
IENTAWCYTTDPETRWEYCAVGYLDPRCQATPACQEDPTGVHYRGLLSRTIGDHTCQAWTSQDPNQHTKTPANYPNAGLD
NNYCRNPDGVNTAWCYTTNPETRWEYCAVGYLDPRCQGSVV

>XP_784460.3 peroxiredoxin-4 [Strongylocentrotus purpuratus | PB0239
MNSKMIRILSLILAVSTLVAAEEACHSFAGGHVYPGETPRSTAHAVHWSKVQISKPAPVFEGTAVVEGEFKAMKLSDFAG
KYLVLVFYPLDFTFVCPTEIIAFSDRVDEFRAINTEVVAISVDSQFTHLAWINTPRTQGGLGPIKLPILSDLTHQIAKDY
GVLLEDLGHTLRGLFIIDDKGVLRQITMNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSDTIIPNPADKLKYFA
KQPNGGNA
>XP_030842214.1 SH3 and PX domain-containing protein 2A isoform X3 [Strongylocentrotus purpuratus | PB0241
MGKRTVVNANVTDIEKRREPTKHYVYIIHVTWSDGSVNVVYRRYSTFFDFQNKLLSKFPEEAGANNPSSRCIPFLPGKKL
FGRSHIREVALKRLSPIDEYCTALVKLPGKISDSKEVINFFTPTPEDVSPPSPDGGGESTRGRADIGNISEPIQAEQYIV
VADYKKQQKNEVELTAGDLVEVFEKNDNGWWFVTVHDQHGWAPGTFLQNPDGQEEEDEETLIPGNDESYITNNAYQGQAE
DEISFETGVVVTVIQKSLDGWWKVSYQGKQGWAPATFLQIYKGPSGVTPKHPTQSIGNVMLLKSGSDSKPKPGPGPGSSG
RPQPPVQPRDEPGQLYSNYDAEVKPTPPRRATVKKSVRRGGVRQTKPKLKKVMEHYTTDSFQGAAGEGSISFESGQKVEV
LEENDGGWWYVKMNGQEGWAPSNYIEKREVSSRINGKPSLGNLDEETGEDKVPPVLPARPAFGSGGSGAFKPVAKKSTPP
PVDRSNSPSFTNRKAVTNNGRGGGDGVRRGSGGVGAGGNMMAALKKQLEKSSVGESSSPAIPARPGVAPKLSKPTAQPYC
NRDAAYITTSSYVNDENDGLSFKEGQRVEVIKKDDSGWWSVRIGNTEGWVPNTFLEKI
>XP_011682724.1 transthyretin isoform X2 [Strongylocentrotus purpuratus | PB0242
MHSGKEPRNMNCAVDDKLYFRKGSRSTSQRVVQASERERLFKEFHDSPSGGHGGLNVTFRKISQRYYWRGLMSYLKIKVK
QCQVCQNRELWPHMKVTSKEQKQAKRKTSLKRTAGGKPNSPLTSHVLDTARGSPAANLRIEVYHLMAGQWKKISEGQTNS
DGRCPGLLTMEQFIPGIYKILFDTGSYFKANNIKGFYPFVEIVFEIEDVNQHYHVPLLLSPFSYSTYRGS

>XP_003725665.2 lipoma-preferred partner isoform X4 [Strongylocentrotus purpuratus | PB0244
MTTMQRLNQDLDQLDSLRPGGQLSQNGQLQPGTIYTQNITTTQTFYGSQPKKFAPVVGPKPRSQNALPPSGSKGLPSYSP
VDLPPPPSPDQAYGGRDDAPLPPPPPELSGSSYPPKPAPTMQTYNEPHPAVQPGYRQPSYRQQTSPTPGPSPAPKPAPAG
LKGPDWSYHVPQPTDQPITSPAKSGAEAEIDALTNLLVANMGTTQEPEGEFFGMCSRCSNKVVGENNGCTAMEQVYHVDC
FTCENNCGTKLRGQPFYALEGKAFCEHCYVNSLEKCSTCSQPITDRILRATGKPYHPDCFTCVVCGKSLDGVPFTVDATN
QIHCIEDFHRKFAPRCSVCLHPIMPDDGQEETVRIVALDRSFHVHCYKCEDCGVLLSSEADGRGCYPLDDHILCRECNGK
RVQSIS
>NP_001027543.1 beta-catenin [Strongylocentrotus purpuratus | PB0245
MEQARYSNQQQPVNPQQKGYGGPGLQDLPKQDPMQNTMEWQHHGYGMDSGFQSNATSHAPSVSSKSRVEDGGGGGGEEAG
AQGMFDWDAGYGQAYTQEQVDEMNQQLTQTRSQRVRAAMFPETLEEGVQIPSTQFDPAHPTAVQRLSEPSQMLKHAVVNL
INYQDDADLATRAIPELTKLLNDDDLVVVNQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAMSNSNDAETTRCAAGTLH
NLSHHRAGLLQIFKSGGIPALIKLLSSPVESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVALLSRNNPKFLAITTD
CLQILAYGNQESKLIILASGGPAALVHIMRTYEYEKLLWTTSRVLKVLSVCHNNKPGIVEAGGMSALGLHLGHQSNRLVQ
NCLWTLRNLSDCHRGTDDIEPLLQMLVQLLASNDINVVTCACGILSNLTCNNTRNKMIVSQMAGVEALVQTLMKAGDREE
ITEPAVCALRHVTSRHPGAEMCQNTVRLNYGIPVIVKLLHPPSRWPLIKATVGLIRNLALCSANHAPLREQGALHRLVQL
LMRAHQDTQRRSSMGSTGSQGGNYADGVRMEDIVEGTTGALHILARDSHNRALIQGLNCIPLFVQLLYSNIENIQRVAAG
VLSELSLEKQGAEMIEQEGATAPLTELLHSRNEGVATYAAAVLYRMSDDKPQDYKKRISVELGNSLFRGDSVPWGDPLDM
PSDNQILPPSSMGGHPSDSSYPQHGSVHSLHSNHGEYRQPPPTMQGYHDGTGPIEPMMQDLDLGGGGDFGMDPGLPDMGP
PTNDLSLDSIPPADNTGLAFFDTDL
>XP_798253.3 ras-related C3 botulinum toxin substrate 1 [Strongylocentrotus purpuratus | PB0246
MQSIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLI
CFSVVSPVSYENVRAKWAPEVRHHCPSTPIILVGTKLDLRDDPDTINKLKERNQYPIRYQQGIQMHKEINAVKYLECSAL
TQKGLKMVFEEAIRVFLYPPKVPKKRRHQCTVL
>XP_011664853.1 fermitin family homolog 2 isoform X1 [Strongylocentrotus purpuratus | PB0247
MDFKNMTNPEGYKFTLPDGRYADGTWDLIIYITNLETEVTITGIEGNLSIGDLMLKTVQAAGVQIDWSDHMVWWEEKKIW
LHKTRLTLNNYRVQAGTKLHFTPCHKTLRLQLPDMQLVDRRVDFSKNVVFAVQEVCNELGINHAEELSMLRKPEKGSKQN
GKSTGTGTGRKKKQRGDRDSMASSNSNEAASIGSLDGIGPATPTRKPSPGNYRTPGQNGNPGYSSGSNYSGSIENLNTSL
VNSPQRPSREAFDGLIRPTSYRDKASMNAGWLDSNKSLMEQDVRENDTLMLRFKYYVFYNLPQPGSSDIKHVRADSVRIN
QIYEQAKWSILREEVECTHEEMMMFAALQLQVSMQSQKPQQEVDGPSDGQDDIDKALTNLQVSLEGQTVSPGHTDITSVP
ELSGVLRYLKPKKFTLKGYKKAWFVFRDLHLSSYKNEEESNGQAIQRINLKGCEASPDVSIAAEKFCIKLLSVSPEGTQE
LILRCDSEDQYAKWMAACRLASKGKSMADSTYSLEVEEIKAFLSMQQSKKDSNNPIIPTDMPELKPENFVSPRALKKYKA
KEIARSILDAHSGLQTLSLIDAKLNYIKAWQALPEYGITFFVVRTHGTRKDELLGLAYNRMIKMDINTGDLQKTWRYSTM
THWNVNWETRELIIGMEDEQIQMACLTCDCKIVHEYIGGSIFLALRKQDKNQVLDMDMFMKLTGGSESGVLE
>XP_030848750.1 vinculin isoform X6 [Strongylocentrotus purpuratus | PB0248
MPVFHTKTIEAILDPVAQQVSQLVILHEEAQDGNAMPDLSRPVMAVSAAVQNLVKVGRDTANSTDDKILKQEMPPAFQGV
EQSATKLYEAAMMLKEDPYSSPARKMLIDGARGILSGTSDLLLCFDQSEVRKIVRVAKGVLEYLAVSEVVESMEDLVTFV
KNLSPGMANLANKVTGRSKELTHTAHANGLVNHTENLKRTTPILVSSIKIFVTTLQKGGAGRDEAQQNRNFIIGRMSHDV
NEIIRILQLTSADDDDWSMDDLTIMKKSLLNITNQMNMAQTWLANSNAEPGGLGEKAVRDILRDARRVADRLEGPQREHL
LATINEIEVMMNELCALRAKGQGNSPRALQLAKQIAEKLGYLHQEVDFAVKDAVKSGVTRTAYTLAGKVEQAQKWLRNPA
QDDKGVGRRAVAGIVAQGRKVAQNLSEPERGELLRLCDEVESLSQQITDLVNRGQGNSPQCLDAARRLAERLPSLQKMIE
NALAKEVAEVFMDTTTPLKELERAAKAPADDPNRQQTYTSKATIFLTHANKISDTAKLVAEAGASNDRPLVEELNNKAQE
VKDLAPQVVAAGKVLLLNPGEQTAVSHFDELKREYMGKVETLTDLVDQAVDTVEFVKASEEAIKRDSEKVAQAIQQNDPN
VIAAKASSIARRAQRVAVVASKEAANSEDPKFVQDVSRAANQLSGDIPPSVTAAKGVTLNPADRNAQDKWFTANKQVQSD
VGDVRQALTVNQEPIMPPPPDMSRLQLEEAAPPRPPLPGDVPPPRPPPPEDTSLPLPEQGSHQPIMQAAYDLHVETEQWS
SKDNDLIAAAKRMAQLMAAMSKHVSGEKTSKKELIEIAKKIAQASLEVVRLAGEIAAQCTDKRMKNNLLQVCERIPTIST
QLKILSTVKAVMLGSQESEEDMEATEMLVGNAQNLMKAVKETVRAAKAASIKIRTDAGYKMRWVRQRPWYQ
>NP_001116977.1 bone morphogenetic protein BMP2/4 precursor [Strongylocentrotus purpuratus | PB0251
MVTTSHWGQLVVPLVCCCVVVGGWPGSTSSTTSSSSSSERSSQNEGDQNRKAQVIEAFESTLLGMFGLKERPRPQGKLRV
PQYMMDLYRSHTEAEDGINMLFDFKHVSTGTANTIRSYHHQDAGQVVSTEHHRHKVIFNVSTMPEEEVMTTAELRLFRKD
LDEHHIVKRHALHDRESLKPIHYMQRINVYHILKPVARNRDTIKRLIDTRLVDVRNASWESFDVRPAMRVWLEEPEKNHG
LEIELIDSRGRPSPNHHHVRVTREADPSKVEELENEEEDRWFQTRPQIVTYSDDGRTKRSPSSSSSGRGQKKRKGKRLKA
NCRRHELYVDFSDVHWNDWIVAPAGYQAYYCRGECPFPLAEHLNTTNHAIVQTLVNSVNPALVPKACCVPTELSAISMLY
LDEYEKVVLKNYQDMVVEGCGCR
>XP_796266.4 R-spondin-2 isoform X1 [Strongylocentrotus purpuratus | PB0252
MEPEGLLFAITFFCGLLATMEGKHRGKGCPLGCSTCSVYNGCITCKPRYLFLLHRSGMKQVGICTHACPVGFYPNSAGDY
HRCSRCRIENCDTCYSRTFCSRCQPPYVGLYGKCVLQCPDSMYVNEMTSQCEVKVDCAVSPWSPWSPCIKKGQTCGFKWG
EHRRYREVVARPTPEAEPCPELFQGEKCRMHPRYCPGQLPRKPKDKGKRKKEKGTTDNQEGTTRKNDGNKQKDRTNRRSK
KKDRQKPSPRDERRQRQRKEEHLIDFPLSTRRTI
>XP_011678253.2 R-spondin-2 isoform X2 [Strongylocentrotus purpuratus | PB0253
MEPEGLLFAITFFCGLLATMEGKHRGCPLGCSTCSVYNGCITCKPRYLFLLHRSGMKQVGICTHACPVGFYPNSAGDYHR
CSRCRIENCDTCYSRTFCSRCQPPYVGLYGKCVLQCPDSMYVNEMTSQCEVKVDCAVSPWSPWSPCIKKGQTCGFKWGEH
RRYREVVARPTPEAEPCPELFQGEKCRMHPRYCPGQLPRKPKDKGKRKKEKGTTDNQEGTTRKNDGNKQKDRTNRRSKKK
DRQKPSPRDERRQRQRKEEHLIDFPLSTRRTI
>XP_011678253.2 R-spondin-2 isoform X2 [Strongylocentrotus purpuratus | PB0254
MEPEGLLFAITFFCGLLATMEGKHRGCPLGCSTCSVYNGCITCKPRYLFLLHRSGMKQVGICTHACPVGFYPNSAGDYHR
CSRCRIENCDTCYSRTFCSRCQPPYVGLYGKCVLQCPDSMYVNEMTSQCEVKVDCAVSPWSPWSPCIKKGQTCGFKWGEH
RRYREVVARPTPEAEPCPELFQGEKCRMHPRYCPGQLPRKPKDKGKRKKEKGTTDNQEGTTRKNDGNKQKDRTNRRSKKK
DRQKPSPRDERRQRQRKEEHLIDFPLSTRRTI
>XP_796266.4 R-spondin-2 isoform X1 [Strongylocentrotus purpuratus | PB0255
MEPEGLLFAITFFCGLLATMEGKHRGKGCPLGCSTCSVYNGCITCKPRYLFLLHRSGMKQVGICTHACPVGFYPNSAGDY
HRCSRCRIENCDTCYSRTFCSRCQPPYVGLYGKCVLQCPDSMYVNEMTSQCEVKVDCAVSPWSPWSPCIKKGQTCGFKWG
EHRRYREVVARPTPEAEPCPELFQGEKCRMHPRYCPGQLPRKPKDKGKRKKEKGTTDNQEGTTRKNDGNKQKDRTNRRSK
KKDRQKPSPRDERRQRQRKEEHLIDFPLSTRRTI