![]() |
| PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
| PB0084 | P05997 | Collagen alpha-2(V) chain | COL5A2 | EDSC, EDSCL2, collagen type V alpha 2 chain | Homo_sapiens | Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices (By similarity). |
| Domains | Gene Ontology |
| PF00093 (VWC) PF01391 (5_Collagen) PF01410 (COLFI) |
GO:0005201 (enables) extracellular matrix structural constituent
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength GO:0046332 (enables) SMAD binding GO:0046872 (enables) metal ion binding GO:0001501 (involved in) skeletal system development GO:0001503 (involved in) ossification GO:0030198 (involved in) extracellular matrix organization GO:0030199 (involved in) collagen fibril organization GO:0043588 (involved in) skin development GO:0048592 (involved in) eye morphogenesis GO:0071230 (involved in) cellular response to amino acid stimulus GO:1903225 (involved in) negative regulation of endodermal cell differentiation GO:0005615 (is active in) extracellular space GO:0005576 (located in) extracellular region GO:0005788 (located in) endoplasmic reticulum lumen GO:0031012 (located in) extracellular matrix GO:0005581 (part of) collagen trimer GO:0005588 (part of) collagen type V trimer GO:0062023 (part of) collagen-containing extracellular matrix |
| External Links | Description |
| Intact | Open source database system and analysis tools for molecular interaction data. |
| Protein Atlas | An open access resource for human proteins |
| InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |