PB0073

DATABASE

Click here to access PB0073 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0073	Q8NHW6	Otospiralin	OTOS	OTOSP	Homo_sapiens	May be essential for the survival of the neurosensory epithelium of the inner ear.

Domains	Gene Ontology
PF15182 (OTOS)	GO:0005515 (enables) protein binding GO:0007605 (involved in) sensory perception of sound GO:0005576 (located in) extracellular region

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)
Selected proteins from model organisms

>sp|Q8NHW6|OTOSP_HUMAN Otospiralin OS=Homo sapiens OX=9606 GN=OTOS PE=1 SV=1
MQACMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAY
PQIEDMARTFFAHFPLGSTLGFHVPYQED
>tr|A0A286Y9F3|A0A286Y9F3_DANRE Otospiralin OS=Danio rerio OX=7955 GN=otos PE=4 SV=1
MKWSMFFCVFLLCFLANNLSDARVIPEGVPYENPPAVPYWSYSTSDFWNYVEYFRSIGAY
DQINQLARTFFAHQHLGDTLGYEVAEQHEH
>NP_631927.1 otospiralin precursor [Rattus norvegicus]
MQPCVLWWLALGLLLGIPAGAKPTPEEADPNAQPPAMPYWPFSTSDFWNYVQYFQSQGAYPQIEDMARTF
FAHFPLGSTLGFHVPYQED
>KAB0385055.1 hypothetical protein FD755_000011 [Muntiacus reevesi]
MPASLLPGLALCLLLTPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTL
GFHVPYREE
>XP_043318099.1 otospiralin [Cervus canadensis]
MPAHLLPGLALCLLLALLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTL
GFHVPYREE
>KAB0355917.1 hypothetical protein FD754_000073 [Muntiacus muntjak]
MPARLLPGLALCLLLAPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTL
GFQVPYREE
>KAF4022077.1 hypothetical protein G4228_013464 [Cervus hanglu yarkandensis]
MPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYREE
>NP_001087267.1 otospiralin L homeolog precursor [Xenopus laevis]
MKLLLIGLYFSCVLLGTFIDARPVYEEEDPYLDAPAHPYWPFSTSDFWLYVEHFRSLGAYDKINDMARTFFAHYPIGDTL
GYTSKNHDE

>NP_694754.1 otospiralin precursor [Mus musculus]
MQACVLWWLALGMLLGIPAGAKPMPEEADPHTQPPAMPYWPFSTSDFWNYVQYFQTQGAYPQIEDMARTF
FAHFPLGSTLGFHVPYQED

>XP_009442965.1 otospiralin isoform X1 [Pan troglodytes]
MGGLALPGFILLQVGLSRRSGSTGKMQACMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTS
DFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYQED

>XP_534625.2 otospiralin [Canis lupus familiaris]
MMKACLVPGVALCLLLGPLAGAKPVQEEGGPYAEPPAMPYWPFSTSDFWNYVQYFQALGAYPQVEDLART
FFAHFPLGTTLGFHVPYQQD

>XP_024845504.1 otospiralin isoform X1 [Bos taurus]
MPARLPPGLVLCLLLAPLAGGGRLSSCAVPVGGGVPPRGLGVTALPSLAGAKPVQEEGDPHAELPAMPYW
PFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYREE

>XP_002813109.1 otospiralin [Pongo abelii]
MGGLALPGFILLQVGLSRRSGSTGKMQACMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTS
DFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYQED

>XP_005672420.1 otospiralin [Sus scrofa]
MGCQGSGLGKTKACLVPGLALCLLLGPLAGAKPVQDDRDPYAEPPALPYWPFSTSDFWSYVQHLQALGAY
PQLEDMARVFFAHFPLGTTLGFHAPYREE

>NP_001264635.1 otospiralin precursor [Gallus gallus]
MKCIGFLFFCMLMSITDARSVLEGDDREPVAMPYWPFSSSDFWSYVEYFRTLGAYNRIAELARALFAQLP
AGSHLGLHRPVREE

>XP_008963885.1 otospiralin [Pan paniscus]
MGGLALPGFILLQVGLSRRSGSTGKMQACMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTS
DFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYQED

>XP_003991353.2 otospiralin isoform X1 [Felis catus]
MFSRELPGAGVLGGSRGPHGRPVSPSGVLVLQGDRSSIGWWKMHLGKMKACLVQGVAFCLLLGPLAGAKP
VQEEGDPYAEPPAMPYWPFSTSDFWNYVQYFQTMGAYPQLEDLARTFFAHFPLGTTLGFHVPYQQD

>XP_027821508.1 otospiralin [Ovis aries]
MPARLLPGLALCLLLAPLAGAKPVQEEGDPYAELPAMPYWPFSASDFWNYVQHFQALGAYPQLEDMARTF
FAHFPLGTTLGFHVPYREE

>XP_011487403.1 otospiralin [Oryzias latipes]
MKLLWLSVLCLFACCLGEARVIPEGAPYEQPPADPYWPYSTSDFWNYVEYFKSIGAYEQINQLARTFFAH
QNLRDTLGYDTHAGYEH

>XP_005505115.1 otospiralin [Columba livia]
MTFICLLFFFMLMNILTDARSIHDGDALYRESAALPYWPFSSSDFWSYVEYFRTLGAYDRVEEMARTLFA
QFPFGSRLGYHVPTAQH

>XP_006016103.1 otospiralin isoform X1 [Alligator sinensis]
MKFIFIGLVFFCILMNMLTDARPIQDEDDPYQVPASMPYWPFWSNDFWSYVEYFRTLGAYNRINEMARTF
FAHYPIGNGLGYHVPAHEH

>XP_006259335.1 PREDICTED: otospiralin [Alligator mississippiensis]
MKFIFIGLVFFCMLMNMLTDARPIQDEDDPYQVPASMPYWPFWSNDFWSYVEYFRTLGAYNRINEMARTF
FAHYPIGNGLGYHVPAYEH

>XP_031410992.1 otospiralin [Meleagris gallopavo]
MKCIGFLFFWMLMNIITDARSILEGDDREPVAMPYWPFSSSDFWSYMEYFRTLGAYNRIAELARALFAQL
PTGSRLGLHLPAHED

>XP_017902038.1 PREDICTED: otospiralin [Capra hircus]
MPACLLPGLALCLLLVPLAGAKPLQEEGDPYAELPAMPYWPFSVSDFWNYVQHFQALGAYPQLEDMARTF
FAHFPLGTTLGFHVPYREE

>XP_015810961.1 PREDICTED: otospiralin [Nothobranchius furzeri]
MKLVCLGVLLCLFFSRLGEARVIPEGVPSDEPPAVPYWPYSTSDFWNYVEYFRSIGAYNHINEMARAFYA
HQHLGNTLGYESNQGHEH

>XP_020768892.1 otospiralin [Odocoileus virginianus texanus]
MLGEPEESERLRQAPLGCRAGQEQLQGGSGGGVPPGGLRVTALPSLAGAKPVQEEGDPYAELPATPYWPF
STSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGSTLGFHVPYREE

>XP_030253593.1 otospiralin-like [Sparus aurata]
MKLLVSIGVLLGLFVCHLTEARVIPEGVPYDEPPAVPYWPYSTSDFWNYVEYFRSIGAYNHINEMARAFF
AHQPLGDTLGYESNQGHEH

>XP_040204930.1 otospiralin [Rana temporaria]
MKLLVIALYFSCILLGAILDARPIHEEDDRYLDAPAHPYWPFSTSDFWQYVNHFRSMGAYENINDLARTF
FAHYPIEETLGYDHNDH

Mafft alignment of selected proteins

>sp|Q8NHW6|OTOSP_HUMAN Otospiralin OS=Homo sapiens OX=9606 GN=OTOS PE=1 SV=1
--------------------------------------------------MQ-ACMVPGL
ALCLLLGP------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPY-QED
>tr|A0A286Y9F3|A0A286Y9F3_DANRE Otospiralin OS=Danio rerio OX=7955 GN=otos PE=4 SV=1
--------------------------------------------------MKWSMFFCVF
LLCFLANN------------------------------LSDARVIP-EGVPYENPPAVPY
WSYSTSDFWNYVEYFRSIGAYDQINQLARTFFAHQHLGDTLGYEVAEQHEH
>NP_631927.1 otospiralin precursor [Rattus norvegicus]
--------------------------------------------------MQ-PCVLWWL
ALGLLLGI------------------------------PAGAKPTPEEADPNAQPPAMPY
WPFSTSDFWNYVQYFQSQGAYPQIEDMARTFFAHFPLGSTLGFHVPY-QED
>KAB0385055.1 hypothetical protein FD755_000011 [Muntiacus reevesi]
--------------------------------------------------MP-ASLLPGL
ALCLLLTP------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPY-REE
>XP_043318099.1 otospiralin [Cervus canadensis]
--------------------------------------------------MP-AHLLPGL
ALCLLLAL------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPY-REE
>KAB0355917.1 hypothetical protein FD754_000073 [Muntiacus muntjak]
--------------------------------------------------MP-ARLLPGL
ALCLLLAP------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFQVPY-REE
>KAF4022077.1 hypothetical protein G4228_013464 [Cervus hanglu yarkandensis]
------------------------------------------------------------
---------------------------------------------------------MPY
WPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPY-REE
>NP_001087267.1 otospiralin L homeolog precursor [Xenopus laevis]
--------------------------------------------------MK-LLLIGLY
FSCVLLGT------------------------------FIDARPVYEEEDPYLDAPAHPY
WPFSTSDFWLYVEHFRSLGAYDKINDMARTFFAHYPIGDTLGYTSKN-HDE
>NP_694754.1 otospiralin precursor [Mus musculus]
--------------------------------------------------MQ-ACVLWWL
ALGMLLGI------------------------------PAGAKPMPEEADPHTQPPAMPY
WPFSTSDFWNYVQYFQTQGAYPQIEDMARTFFAHFPLGSTLGFHVPY-QED
>XP_009442965.1 otospiralin isoform X1 [Pan troglodytes]
MGGLALPGFILL----------------------QVGLSRR---SGSTGKMQ-ACMVPGL
ALCLLLGP------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPY-QED
>XP_534625.2 otospiralin [Canis lupus familiaris]
M-------------------------------------------------MK-ACLVPGV
ALCLLLGP------------------------------LAGAKPVQEEGGPYAEPPAMPY
WPFSTSDFWNYVQYFQALGAYPQVEDLARTFFAHFPLGTTLGFHVPY-QQD
>XP_024845504.1 otospiralin isoform X1 [Bos taurus]
--------------------------------------------------MP-ARLPPGL
VLCLLLAPLAGGGRLSSCAVPVGGGVPPRGLGVTALPSLAGAKPVQEEGDPHAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPY-REE
>XP_002813109.1 otospiralin [Pongo abelii]
MGGLALPGFILL----------------------QVGLSRR---SGSTGKMQ-ACMVPGL
ALCLLLGP------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPY-QED
>XP_005672420.1 otospiralin [Sus scrofa]
-------------------------------------MGCQ---GSGLGKTK-ACLVPGL
ALCLLLGP------------------------------LAGAKPVQDDRDPYAEPPALPY
WPFSTSDFWSYVQHLQALGAYPQLEDMARVFFAHFPLGTTLGFHAPY-REE
>NP_001264635.1 otospiralin precursor [Gallus gallus]
-----------------------------------------------------MKCIGFL
FFCMLMS-------------------------------ITDARSVLEGDD--REPVAMPY
WPFSSSDFWSYVEYFRTLGAYNRIAELARALFAQLPAGSHLGLHRPV-REE
>XP_008963885.1 otospiralin [Pan paniscus]
MGGLALPGFILL----------------------QVGLSRR---SGSTGKMQ-ACMVPGL
ALCLLLGP------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPY-QED
>XP_003991353.2 otospiralin isoform X1 [Felis catus]
MFSRELPGAGVLGGSRGPHGRPVSPSGVLVLQGDRSSIGWW---KMHLGKMK-ACLVQGV
AFCLLLGP------------------------------LAGAKPVQEEGDPYAEPPAMPY
WPFSTSDFWNYVQYFQTMGAYPQLEDLARTFFAHFPLGTTLGFHVPY-QQD
>XP_027821508.1 otospiralin [Ovis aries]
--------------------------------------------------MP-ARLLPGL
ALCLLLAP------------------------------LAGAKPVQEEGDPYAELPAMPY
WPFSASDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPY-REE
>XP_011487403.1 otospiralin [Oryzias latipes]
--------------------------------------------------MK-LLWLSV-
-LCLFACC------------------------------LGEARVIP-EGAPYEQPPADPY
WPYSTSDFWNYVEYFKSIGAYEQINQLARTFFAHQNLRDTLGYDTHAGYEH
>XP_005505115.1 otospiralin [Columba livia]
-----------------------------------------------------MTFICLL
FFFMLMNI------------------------------LTDARSIHDGDALYRESAALPY
WPFSSSDFWSYVEYFRTLGAYDRVEEMARTLFAQFPFGSRLGYHVPT-AQH
>XP_006016103.1 otospiralin isoform X1 [Alligator sinensis]
--------------------------------------------------MK-FIFIGLV
FFCILMNM------------------------------LTDARPIQDEDDPYQVPASMPY
WPFWSNDFWSYVEYFRTLGAYNRINEMARTFFAHYPIGNGLGYHVPA-HEH
>XP_006259335.1 PREDICTED: otospiralin [Alligator mississippiensis]
--------------------------------------------------MK-FIFIGLV
FFCMLMNM------------------------------LTDARPIQDEDDPYQVPASMPY
WPFWSNDFWSYVEYFRTLGAYNRINEMARTFFAHYPIGNGLGYHVPA-YEH
>XP_031410992.1 otospiralin [Meleagris gallopavo]
-----------------------------------------------------MKCIGFL
FFWMLMNI------------------------------ITDARSILEGDD--REPVAMPY
WPFSSSDFWSYMEYFRTLGAYNRIAELARALFAQLPTGSRLGLHLPA-HED
>XP_017902038.1 PREDICTED: otospiralin [Capra hircus]
--------------------------------------------------MP-ACLLPGL
ALCLLLVP------------------------------LAGAKPLQEEGDPYAELPAMPY
WPFSVSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPY-REE
>XP_015810961.1 PREDICTED: otospiralin [Nothobranchius furzeri]
--------------------------------------------------MK-LVCLGV-
LLCLFFSR------------------------------LGEARVIP-EGVPSDEPPAVPY
WPYSTSDFWNYVEYFRSIGAYNHINEMARAFYAHQHLGNTLGYESNQGHEH
>XP_020768892.1 otospiralin [Odocoileus virginianus texanus]
MLGEPEESERLR----------------------QAPLGCRAGQEQLQGGSG-GGVPPGG
LRVTALPS------------------------------LAGAKPVQEEGDPYAELPATPY
WPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGSTLGFHVPY-REE
>XP_030253593.1 otospiralin-like [Sparus aurata]
--------------------------------------------------MKLLVSIGV-
LLGLFVCH------------------------------LTEARVIP-EGVPYDEPPAVPY
WPYSTSDFWNYVEYFRSIGAYNHINEMARAFFAHQPLGDTLGYESNQGHEH
>XP_040204930.1 otospiralin [Rana temporaria]
--------------------------------------------------MK-LLVIALY
FSCILLGA------------------------------ILDARPIHEEDDRYLDAPAHPY
WPFSTSDFWQYVNHFRSMGAYENINDLARTFFAHYPIEETLGYDHND-H--

BMGE Cleaned alignment of selected proteins

>sp|Q8NHW6|OTOSP_HUMAN Otospiralin OS=Homo sapiens OX=9606 GN=OTOS PE=1 SV=1
CMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYD
>tr|A0A286Y9F3|A0A286Y9F3_DANRE Otospiralin OS=Danio rerio OX=7955 GN=otos PE=4 SV=1
MFFCVFLLCFLANNLSDARVIP-EGVPYENPPAVPYWSYSTSDFWNYVEYFRSIGAYDQINQLARTFFAHQHLGDTLGYEVAEH
>NP_631927.1 otospiralin precursor [Rattus norvegicus]
CVLWWLALGLLLGIPAGAKPTPEEADPNAQPPAMPYWPFSTSDFWNYVQYFQSQGAYPQIEDMARTFFAHFPLGSTLGFHVPYD
>KAB0385055.1 hypothetical protein FD755_000011 [Muntiacus reevesi]
SLLPGLALCLLLTPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYE
>XP_043318099.1 otospiralin [Cervus canadensis]
HLLPGLALCLLLALLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYE
>KAB0355917.1 hypothetical protein FD754_000073 [Muntiacus muntjak]
RLLPGLALCLLLAPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFQVPYE
>KAF4022077.1 hypothetical protein G4228_013464 [Cervus hanglu yarkandensis]
---------------------------------MPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYE
>NP_001087267.1 otospiralin L homeolog precursor [Xenopus laevis]
LLIGLYFSCVLLGTFIDARPVYEEEDPYLDAPAHPYWPFSTSDFWLYVEHFRSLGAYDKINDMARTFFAHYPIGDTLGYTSKNE
>NP_694754.1 otospiralin precursor [Mus musculus]
CVLWWLALGMLLGIPAGAKPMPEEADPHTQPPAMPYWPFSTSDFWNYVQYFQTQGAYPQIEDMARTFFAHFPLGSTLGFHVPYD
>XP_009442965.1 otospiralin isoform X1 [Pan troglodytes]
CMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYD
>XP_534625.2 otospiralin [Canis lupus familiaris]
CLVPGVALCLLLGPLAGAKPVQEEGGPYAEPPAMPYWPFSTSDFWNYVQYFQALGAYPQVEDLARTFFAHFPLGTTLGFHVPYD
>XP_024845504.1 otospiralin isoform X1 [Bos taurus]
RLPPGLVLCLLLAPLAGAKPVQEEGDPHAELPAMPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYE
>XP_002813109.1 otospiralin [Pongo abelii]
CMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYD
>XP_005672420.1 otospiralin [Sus scrofa]
CLVPGLALCLLLGPLAGAKPVQDDRDPYAEPPALPYWPFSTSDFWSYVQHLQALGAYPQLEDMARVFFAHFPLGTTLGFHAPYE
>NP_001264635.1 otospiralin precursor [Gallus gallus]
KCIGFLFFCMLMS-ITDARSVLEGDD--REPVAMPYWPFSSSDFWSYVEYFRTLGAYNRIAELARALFAQLPAGSHLGLHRPVE
>XP_008963885.1 otospiralin [Pan paniscus]
CMVPGLALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYD
>XP_003991353.2 otospiralin isoform X1 [Felis catus]
CLVQGVAFCLLLGPLAGAKPVQEEGDPYAEPPAMPYWPFSTSDFWNYVQYFQTMGAYPQLEDLARTFFAHFPLGTTLGFHVPYD
>XP_027821508.1 otospiralin [Ovis aries]
RLLPGLALCLLLAPLAGAKPVQEEGDPYAELPAMPYWPFSASDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYE
>XP_011487403.1 otospiralin [Oryzias latipes]
LWLSV--LCLFACCLGEARVIP-EGAPYEQPPADPYWPYSTSDFWNYVEYFKSIGAYEQINQLARTFFAHQNLRDTLGYDTHAH
>XP_005505115.1 otospiralin [Columba livia]
TFICLLFFFMLMNILTDARSIHDGDALYRESAALPYWPFSSSDFWSYVEYFRTLGAYDRVEEMARTLFAQFPFGSRLGYHVPTH
>XP_006016103.1 otospiralin isoform X1 [Alligator sinensis]
IFIGLVFFCILMNMLTDARPIQDEDDPYQVPASMPYWPFWSNDFWSYVEYFRTLGAYNRINEMARTFFAHYPIGNGLGYHVPAH
>XP_006259335.1 PREDICTED: otospiralin [Alligator mississippiensis]
IFIGLVFFCMLMNMLTDARPIQDEDDPYQVPASMPYWPFWSNDFWSYVEYFRTLGAYNRINEMARTFFAHYPIGNGLGYHVPAH
>XP_031410992.1 otospiralin [Meleagris gallopavo]
KCIGFLFFWMLMNIITDARSILEGDD--REPVAMPYWPFSSSDFWSYMEYFRTLGAYNRIAELARALFAQLPTGSRLGLHLPAD
>XP_017902038.1 PREDICTED: otospiralin [Capra hircus]
CLLPGLALCLLLVPLAGAKPLQEEGDPYAELPAMPYWPFSVSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGTTLGFHVPYE
>XP_015810961.1 PREDICTED: otospiralin [Nothobranchius furzeri]
VCLGV-LLCLFFSRLGEARVIP-EGVPSDEPPAVPYWPYSTSDFWNYVEYFRSIGAYNHINEMARAFYAHQHLGNTLGYESNQH
>XP_020768892.1 otospiralin [Odocoileus virginianus texanus]
GVPPGGLRVTALPSLAGAKPVQEEGDPYAELPATPYWPFSTSDFWNYVQHFQALGAYPQLEDMARTFFAHFPLGSTLGFHVPYE
>XP_030253593.1 otospiralin-like [Sparus aurata]
VSIGV-LLGLFVCHLTEARVIP-EGVPYDEPPAVPYWPYSTSDFWNYVEYFRSIGAYNHINEMARAFFAHQPLGDTLGYESNQH
>XP_040204930.1 otospiralin [Rana temporaria]
LVIALYFSCILLGAILDARPIHEEDDRYLDAPAHPYWPFSTSDFWQYVNHFRSMGAYENINDLARTFFAHYPIEETLGYDHND-

PhyML tree of selected proteins

(NP_001087267_1_otospiralin_L_homeolog_precursor__Xenopus_laevis_:0.08440502,XP_040204930_1_otospiralin__Rana_temporaria_:0.31189272,((((XP_005505115_1_otospiralin__Columba_livia_:0.15535435,(NP_001264635_1_otospiralin_precursor__Gallus_gallus_:0.09139149,XP_031410992_1_otospiralin__Meleagris_gallopavo_:0.04015814):0.25711996):0.17867542,(XP_006259335_1_PREDICTED__otospiralin__Alligator_mississippiensis_:0.00000001,XP_006016103_1_otospiralin_isoform_X1__Alligator_sinensis_:0.01219479):0.11244603):0.23395147,(XP_030253593_1_otospiralin_like__Sparus_aurata_:0.03040931,(XP_015810961_1_PREDICTED__otospiralin__Nothobranchius_furzeri_:0.09397917,(tr_A0A286Y9F3_A0A286Y9F3_DANRE_Otospiralin_OS_Danio_rerio_OX_7955_GN_otos_PE_4_SV_1:0.21654975,XP_011487403_1_otospiralin__Oryzias_latipes_:0.21600491):0.20538958):0.0476491):0.6011749):0.0291271,(((XP_534625_2_otospiralin__Canis_lupus_familiaris_:0.02884223,XP_003991353_2_otospiralin_isoform_X1__Felis_catus_:0.06508011):0.0319918,(XP_005672420_1_otospiralin__Sus_scrofa_:0.14562234,((XP_002813109_1_otospiralin__Pongo_abelii_:0.00000001,(XP_009442965_1_otospiralin_isoform_X1__Pan_troglodytes_:0.00000001,(sp_Q8NHW6_OTOSP_HUMAN_Otospiralin_OS_Homo_sapiens_OX_9606_GN_OTOS_PE_1_SV_1:0.00000001,XP_008963885_1_otospiralin__Pan_paniscus_:0.00000001):0.00000001):0.00000001):0.03884397,(XP_017902038_1_PREDICTED__otospiralin__Capra_hircus_:0.04442716,(KAB0385055_1_hypothetical_protein_FD755_000011__Muntiacus_reevesi_:0.02667523,(KAF4022077_1_hypothetical_protein_G4228_013464__Cervus_hanglu_yarkandensis_:0.00000001,(XP_043318099_1_otospiralin__Cervus_canadensis_:0.0291607,(XP_027821508_1_otospiralin__Ovis_aries_:0.01444999,(KAB0355917_1_hypothetical_protein_FD754_000073__Muntiacus_muntjak_:0.01438139,(XP_020768892_1_otospiralin__Odocoileus_virginianus_texanus_:0.22277879,XP_024845504_1_otospiralin_isoform_X1__Bos_taurus_:0.01504916):0.02892567):0.00000001):0.00000002):0.00003833):0.01475945):0.00261706):0.04994525):0.01567965):0.01714433):0.06658962,(NP_631927_1_otospiralin_precursor__Rattus_norvegicus_:0.01953476,NP_694754_1_otospiralin_precursor__Mus_musculus_:0.05280897):0.22713183):0.52905243):0.44258746);

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)