PB0056

DATABASE

Click here to access PB0056 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0056	P08294	Extracellular superoxide dismutase [Cu-Zn]	SOD3	EC-SOD, superoxide dismutase 3	Homo_sapiens	Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.

Domains

Gene Ontology

PF00080 (Sod_Cu)

GO:0004784 (enables) superoxide dismutase activity GO:0005507 (enables) copper ion binding GO:0005515 (enables) protein binding GO:0008201 (enables) heparin binding GO:0016209 (enables) antioxidant activity GO:0016491 (enables) oxidoreductase activity GO:0046872 (enables) metal ion binding GO:0001666 (involved in) response to hypoxia GO:0006801 (involved in) superoxide metabolic process GO:0006979 (involved in) response to oxidative stress GO:0019430 (involved in) removal of superoxide radicals GO:0046688 (involved in) response to copper ion GO:0097746 (involved in) blood vessel diameter maintenance GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005634 (located in) nucleus GO:0005737 (located in) cytoplasm GO:0005794 (located in) Golgi apparatus GO:0005796 (located in) Golgi lumen GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P08294|SODE_HUMAN Extracellular superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD3 PE=1 SV=2 MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALH AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA >tr|E9QIM2|E9QIM2_DANRE Superoxide dismutase [Cu-Zn] OS=Danio rerio OX=7955 GN=sod3b PE=3 SV=1 MIRFNILPLLAFLLSCHVLFCGSGSGLAYASNSDSLQAVCRMQPNTRLEPGMPRVYGHIL FRQSGPKEKLSVTFRLYGLPADSQQPRAMHIHEYGDLSRGCDSTGGHYNPLNVNHPQHPG DFGNFVPVNKKIRQSLESPATLFGKLSIVGRSVVIHEGKDDLGRGGNVGSLLNGNAGGRL ACCVIGLRNPQN
Selected proteins from model organisms >sp|P08294|SODE_HUMAN Extracellular superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD3 PE=1 SV=2 MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALH AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA >tr|E9QIM2|E9QIM2_DANRE Superoxide dismutase [Cu-Zn] OS=Danio rerio OX=7955 GN=sod3b PE=3 SV=1 MIRFNILPLLAFLLSCHVLFCGSGSGLAYASNSDSLQAVCRMQPNTRLEPGMPRVYGHIL FRQSGPKEKLSVTFRLYGLPADSQQPRAMHIHEYGDLSRGCDSTGGHYNPLNVNHPQHPG DFGNFVPVNKKIRQSLESPATLFGKLSIVGRSVVIHEGKDDLGRGGNVGSLLNGNAGGRL ACCVIGLRNPQN >NP_035565.1 extracellular superoxide dismutase [Cu-Zn] precursor [Mus musculus] MLAFLFYGLLLAACGSVTMSNPGESSFDLADRLDPVEKIDRLDLVEKIGDTHAKVLEIWMELGRRREVDA AEMHAICRVQPSATLPPDQPQITGLVLFRQLGPGSRLEAYFSLEGFPAEQNASNRAIHVHEFGDLSQGCD STGPHYNPMEVPHPQHPGDFGNFVVRNGQLWRHRVGLTASLAGPHAILGRSVVVHAGEDDLGKGGNQASL QNGNAGRRLACCVVGTSSSAAWESQTKERKKRRRESECKTT >XP_038068816.1 superoxide dismutase [Cu-Zn]-like [Patiria miniata] MAVRMSAPRHLLVIALLSCGFTHAADRLPLSAQLIRMQSQIDILRRDVDQLLGELHRTHGPEPPNLNLEGDGNVYAHCRM VPNGIYDPDTYEPIVGDIDMRQRAVGGPMDVEVFLYGFMTPKSVHALHVHTYGDLRHGCGSAGSHYNPGGNNHSAPYDKD RHMGDWGNIQVDDFGMVEETFTDKVATLVGPNSILGRTIVIHIGEDDLGKGGTADSKKTGNAGGRLGCCVIGRSDGSAWI GY >KAB0342939.1 hypothetical protein FD754_019865 [Muntiacus muntjak] MLALLCACLLLVACDSGASADQLLHQMIMEEQIRDMHTKVTEIWQETVMQRRATAIDPDAALHAVCRVLPSATLEAEQPR VSGLVLFRQIRPGTLLEAFFHLEGFQNEPNGTSHAIHVHEFGDLSQGCDSTGPHYNPMSVPHPQHPGDFGNFAVRNGQVW KHRYDLAASLTGPHSIAGRAVVVHAGEDDMGRGGNQASLENGNAGRRLACCVVGLCGPGPWARKAQEHAERRKRRLESEC KAGAAARERA >XP_043294215.1 extracellular superoxide dismutase [Cu-Zn] [Cervus canadensis] MLALLCAYLLLVACDSAASTDQLLHQMIMEEQIRDMHTKVTEIWQETVTQRRAAAIDPDAALHAVCRVQPSATLEAEQPQ VSGLVLFRQIRPGTLLEAFFHLEGFQDEPNGTSHAIHVHQFGDLSQGCDSTGPHYNPMSVPHPQHPGDFGNFAVRNGQVW KHRYDLAASLTGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRLACCVVGLCGPGPWARKAQEHAERRKRRLESEC KARARRESEPKAL >XP_018098563.1 extracellular superoxide dismutase [Cu-Zn] [Xenopus laevis] MNHLFYMAEVFTICAVLSARSEIVKPVEEELLADTNKKVNELWLNFLNMKPVDNDGIAYATCSVSPSSKLESSEIKVMGL VLFKQVFPSGRLEAIFDLEGFPTDANQSTRAIHIHKYGDLTDGCDSAGGHYNPNSVDHPHHPGDFGNFRVRDGKIQKFLA NLDATLFGPSSVIGRSIVVHKQADDLGKGNNQASLENGNAGKRLACCIIGSSSKNNWEKYIQDSAAPRSLRFSRRVKKG >XP_030247694.1 extracellular superoxide dismutase [Cu-Zn] [Sparus aurata] MRPHGSMSILGALFVLLAGGQQCVSATTDTLAPPEVSQHNGTLYAACKMRPSTSLAEGLPKVYGQALFKQDYPQGKLKVL LRFNGFPTEGDPQPRAVHIHQYGDLSQGCDSTGGHYNPHGVPHPNHPGDFGNFEAQQGKINAMMESEATMFGGMSVIGRA VVIHEKIDDLGRGGDAGSLLHGNAGRRLACCIIGISSPKLWNTHQKLYTRRLRSN >XP_004084336.2 extracellular superoxide dismutase [Cu-Zn] [Oryzias latipes] MSLHRSVRVLEMAFLVWLACSQQCFSTHTDHLLPPEFSQYNGTLYAACKVSPSTSLPDDLPKVYGQALFKQDHGQGKLQV LLQLAGFPEDESPQSRAIHIHQYGDLSQGCISTGGHYNPYGVDHPNHPGDFGNFVAHEGRISEQIESEATLFGGLSVLGR AVVVHETIDDLGQGGDVGSLLHGNAGRRLACCVIGMSSSDLWEEQQKLQSS >XP_015799267.1 PREDICTED: extracellular superoxide dismutase [Cu-Zn] [Nothobranchius furzeri] MHIHGSVRGLQTALLVLLAGHQCVSGDTDILLPPEFSQHNGTLYASCKMRPSSSLPEDLPKVYGQVLFKQELQGKLQVLF QFSGFPATEDLPQPRAVHIHQYGDLSQGCDSTGGHYNPNGVNHPNHPGDFGNFVPQQGKVSDQRESEATLFGGLSVIGRA VVVHEGVDDLGLGGDTGSLMHGNAGPRLACCVIGMSSSSLWNTQAEAVYKTAEEILDPQ >CAE1264788.1 SOD1 [Sepia pharaonis] MSIKAVCVMKGDRDVSGVIHFTQESPTKPVKLTGEIRGMADGKHGFHIHEFGDNTNGCTSAGPHFNPDNKEHGAPTDENR HVGDLGNVDSSGGIANVNIEDKIINLTGPHSIIGRTVVVHADIDDLGKGGHELSKTTGNAGSRLACGVIGITK >XP_030829251.1 superoxide dismutase [Cu-Zn]-like isoform X2 [Strongylocentrotus purpuratus] MQLLLALLSLTALITSSSAVTVNFASCRLTKSENGEVVGRVDLREQSDTNVLQLRLQVDGAKLTLAANSKHGFHVHTYGN ISGSCSTTGGHYNPDGVDHASPTSAQRHVGDLGNVQADASGNIDVSFNDTYASLTGTKAIMGRAFVLHGGEDDIGLGGNA GSLASGNAGPRLACCVIGWATGTDWVY >XP_039262007.1 superoxide dismutase [Cu-Zn]-like [Styela clava] MASPKTAVCILEGSTEGVEGIINFKDMGDGTCSIKGEITGLKTGQHGFHVHQYGDYTNGCTSTGGHFNPYNKEHGGPDDT ERHVGDLGNIMVDESGKATIDITDKQVKLDGEFSVVGRAIVVHADVDDLGRGGFPDSKTTGHAGGRLACGVIGLSPAK >XP_031572834.1 superoxide dismutase [Cu-Zn]-like isoform X2 [Actinia tenebrosa] MKHIAVLSILLVYASVVEVSAQVTVMCXMEPNRVPPSNVKSTVTGTVKLSQQSSSAQTKFTVKLNGLPPYSVHGFHVHNY GDIXSNGCQSCGSHYNPFNATHGGPRDRIRHVGDLGNLMSDDNGRIEAEFTDSLVSLQGNYSVIGRSIVLHAKRDDLGRG KGAARKESLKTGNAGARLGCCAIVYAAPPAPSN >NP_001171498.1 superoxide dismutase 1 [Apis mellifera] MTKAVCVLQGEVKGTIFFEQPESTNSVKVTGQVTGLKKGLHGFHVHEFGDNTNGCTSAGAHFNPLGKDHGGPDSDIRHVG DLGNIEADASGVANVNITDKTIQLQGPHSVIGRTLVVHADPDDLGKGGVELSKTTGNAGARLACGVIGITKV >NP_001021956.1 Superoxide dismutase [Cu-Zn] [Caenorhabditis elegans] MFMNLLTQVSNAIFPQVEAAQKMSNRAVAVLRGETVTGTIWITQKSENDQAVIEGEIKGLTPGLHGFHVHQYGDSTNGCI SAGPHFNPFGKTHGGPKSEIRHVGDLGNVEAGADGVAKIKLTDTLVTLYGPNTVVGRSMVVHAGQDDLGEGVGDKAEESK KTGNAGARAACGVIALAAPQ >AAD14963.2 slow superoxide dismutase, partial [Drosophila melanogaster] VINGDAKGTVFFEQESSGTPVKVSGEVCGLAKGLHGFHVHEFGDNTNGCMSSGPHFNPYGKEHGAPVDENRHLGDLGNIE ATGDCPTKVKITDSKITLFGADSIIGRTVVVHADADDLGQGGHELSKSTGNAGARIGCGVIGIAKV >NP_037012.1 extracellular superoxide dismutase [Cu-Zn] precursor [Rattus norvegicus] MVAFLFCNLLLVACGSVTWTMSDTGESGVDLADRLDLVEKIGDTHSKDLEIWMELGKQREADAREMHAVC RVQPSAMLPPDQPQITGLVLFRQLGPSSRLEASFNLEGFPAEQNTSNHAIHVHEFGDLSQGCESTGPHYN PLGVPHPQHPGDFGNFVVRDGRLWKHRMGLATSLAGPHSILGRAVVVHAGEDDLGKGGNQASVQNGNAGR RLACCVVGTSNSEAWESQTKERKKRRRESECKTT >XP_040525137.1 extracellular superoxide dismutase [Cu-Zn] [Gallus gallus] MLLLLSLVTGLALSASDVVTETGADPSSALLHDIQRKVNDLWQSLLYPVMADNETDGLTYATCEVKPSSK IDADKPQVTGQVLFRQHYSQGKLEAIFHLDGFPLDNNQSGRAIHIHELGDLSDGCNSAGGHYNPFGVNHP RHPGDFGNFSPKDGKIRKYKPNLFATMFGPYSILGRSVVIHEQEDDMGKGNNKASLENGNAGKRLACCVI GICNKNLWEEKQSEAMDRKKRWRRTRLS >XP_009445714.1 extracellular superoxide dismutase [Cu-Zn] [Pan troglodytes] MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALHAACQVQPSAT LDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHP QHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVV GVCGPGLWERQAREHSERKKRRRESECKAA >XP_545973.4 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Canis lupus familiaris] MACLPCSDSDRDPLPGAGLPARPQTAQPKESARIPGCCSLLLRRKALSEELGRCPPPAMLAPALLCAHLL LAAPASRAWPGAAPDEPEPQPQPQPEPEPGPGAVAAQLSDMHDKVTAIWQQLTQRAAEPGAPGSALHAAC RVQPSASLDPAQPRVSGLVLFRQPAPGAPLEAFFHLDGFPAERNGSRRAIHVHRFGDLSPGCEAAGPHYN PRAAPHPHHPGDFGNFAVRDGRVRKHRGGLAASLAGPHSIVGRAVVVHAGEDDLGRGGDPASLDHGNAGR RLACCVVGVCGPLPWARAAREHAERRKRRRDSDCQAA >XP_024849041.1 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Bos taurus] MGHFREHIASARSSGSKPYAASLRGCRKRVAGDEGAEMLRRRRSGRATRASLRCSTLAMLALLCASVVLV AYASADQIQQQMGSNTEEQIRDMHAKVTEIWQEMMQRQAAAIDPDAALHAVCRVLPSATLEAEQPRVSGL VLFRQLRPGALLEAFFHLEGFPNEPNGTNRAIHVHQFGDLSQGCDSTGPHYNPMSVPHPQHPGDFGNFAV RDGQVWKYRSGLAASLTGPHSIAGRAVVVHAGEDDMGRGGNQASLENGNAGRRLACCVVGLCGPGPWARQ TQEHAERKKRRRESECKAV >XP_020956182.1 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Sus scrofa] MPFFPREDHAPEAAPRATNSPGFCQPPSCSDDDGQAGAAPHFPGGKALLEELERCPTPAMLTLLCAYLLL APGASDALTHVDVERPGSHMEEQIRDMQAKVTEIWQELTQQRAAGGGQEAALHATCSMQPSVLLDAAQPQ VTGLVLFRQLRPGALLEAFFHLKGFPAEPNSTSRAIHVHQFGDLSQGCDSTGPHYNPLEVPHPQHPGDFG NFAVRDGQIWRYRSSPGASLFGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRLACCVVALCGPGP WAHQAQEHAEHRKRRRASECKAS >NP_001076101.1 extracellular superoxide dismutase [Cu-Zn] precursor [Oryctolagus cuniculus] MLALVCSCLLLAALPADTWSGPAAVELGSDTVEQIRDTHAKVTEIWQALTQQRAAQGEPAGALHAVCRVQ PSATLDAAQPRVSGLVVFRQLGPGAQLEAFFDLEGFPVEANLSSRAIHVHQFGDLSQGCDSTGAHYNPLA VQHPQHPGDFGNFAVRDGRLWKYRSGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNAASVENGNAGPRLA CCVVGASGPAPWARQAQEHAERKKRRRESECKAA >XP_009238123.2 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Pongo abelii] MSVGEDGGRGCPTPAMLALLCSCLLLAAGASDAWTGEDSVEPNSDSAEWIRDMYAKVTEIWQEVMQRRDD DGALHAACQVQPSATLDATQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGC ESTGPHYNPLAVPHPRHPGDFGNFAVRDGSLWKYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQAS VENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA >XP_010708631.2 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Meleagris gallopavo] MKKWKYKPLCDVTTSTRAPSPALMLLAVQKGTQCHTHMDIEGKAALTLGNFFSLCFGQFPPQAHRARISS LACPRQTLGSLCPSHSTAGDPSPVRRYPTHKQRSRSHQPHAAPVVSDPTSPRGSGVAGLLPSSAAGRFCR LSVTRMLLLLSLVTGLALSAAGVVTETGADPSCASLHDVQRKVNDLWQSLLYPVMADNETDGLTYATCEM KPSSKIGADKPQVTGQVLFRQHYSQGRLEAIFHLDGFPLDNNQSGRAIHIHELGDLSNGCDSTGGHYNPF RVNHPRHPGDFGNFSPKDGKIRKYKSNLFATMFGPYSILGRAIVIHEQEDDMGKGNNKASLENGNAGKRL ACCVIGICNKNLWEEKQFEATDKKKRWLRTRLS >NP_001272604.1 extracellular superoxide dismutase [Cu-Zn] precursor [Capra hircus] MPALLCASLLLVACASAASADQVQQQMGSNTEEQIRDMHAKVTEIWQEMMQRQAAAIDPDAALHAVCRVL PSATLEAEQPRVSGLVLFRQLRPGALLEAFFHLEGFPNEPNGTSRAIHVHQFGDLSQGCDSTGPHYNPMS VLHPQHPGDFGNFAVRDGQVWKYRSNLAASLTGPHSIAGRAVVVHAGEDDLXRGGNQASLENGNAGRRLA CCVVGLCGPGPWAHQAQENAERKKRRRESECKDV >XP_008950433.1 extracellular superoxide dismutase [Cu-Zn] [Pan paniscus] MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALHAACQVQPSAT LDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHP QHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVV GVCGPGLWERQAREHSERKKRRRESECKAA >XP_014951904.2 extracellular superoxide dismutase [Cu-Zn] isoform X2 [Ovis aries] MSLFLAPLSFAEWLTPTQTISEKSCWGQSGAVGRPPRAGSLKQALGTELPFFNGLLLFFSQKRNFSSVTT PPGGCPAQTQTARELPAFLCPAGEVLLLGSQVRERSLKSWRGARLAMPALLCASLLLVACALAASADQVQ QQMGSNTEEQIRDMHAKVTEIWQEMMQRQAAAIDPDAALHAVCRVLPSATLEAEQPRVSGLVLFRQLRPG ALLEAFFHLEGFPNEPNGTSRAIHVHQFGDLSQGCDSTGPHYNPMSVLHPQHPGDFGNFAVRDGQVWKYR SNLAASLTGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRLACCVVGLCGPGPWAHQAQENAERKK RRRESECKAV >XP_004038545.3 extracellular superoxide dismutase [Cu-Zn] [Gorilla gorilla gorilla] MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALHAACQVQPSAT LDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHP QHPGDFGNFAVRDGSLWKYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVV GVCGPGLWERQAREHSERKKRRRQSECKAA >XP_005501341.1 extracellular superoxide dismutase [Cu-Zn] [Columba livia] MLLLLSLVAGLALSASGGVTDKESDSSQEPFQDIETKVNDLWQSLLYPVAPGNESDRMIYATCEMKPSSK IDADKPQVTGQVLFRQYYSYGRLEAIFYLDGFPLDNNQSGRAIHIHELGDLSNGCDATGGHYNPFRVNHP RHPGDFGNFFPKEGKIRKYKTNLFATMFGPYSIMGRSVVIHEQEDDMGKGNNKASLENGNAGKRLACCVI GICNKNLWEEKLSEVTDKKKRGLNKRTQNQV >XP_006024876.1 extracellular superoxide dismutase [Cu-Zn] [Alligator sinensis] MFLSLCLVSVGLFLSLPGVVSGELEPVPETEGLFQELRKKVNDLWQNLLYPQFIRDSDWTAYATCEMKPS SKLDADKPQVTGQILFKQSYPIGKLEAFFDLDGFPSENNQLGRAIHIHKFGDLSDGCNTTGGHYNPFNVN HPHHPGDFGNFYSKEGKIRKYKSNLSATLFGPYTIMGRSVVIHEQEDDMGKGNNKASLENGNAGRRLACC VIGICDKNMWENKFSKFVERRKRGSQNEHRSRPS >XP_006260489.1 PREDICTED: extracellular superoxide dismutase [Cu-Zn] [Alligator mississippiensis] MFLSLCLVSVGLFLSLPGVVSGELEPVPETEGLFQELRKKVNDLWQNLLYPQFIRDSDWTAYATCEMKPS SKLDADKPQVTGQILFKQSYPIGKLEAFFDLDGFPSENNQLGRAIHIHKFGDLSDGCNTTGGHYNPFNVN HPHHPGDFGNFYSKEGKIRKYKSNLSATLFGPYTIMGRSVVIHEQEDDMGKGNNKASLENGNAGRRLACC VIGICDKNMWENKFSKFVERKKRGSQNEHRSRPN >XP_020753289.1 extracellular superoxide dismutase [Cu-Zn] [Odocoileus virginianus texanus] MLALLCVYLLLVACDSAASADQFLHQMYSFMEEQIRDMHTKVTEIWQETVMQRRAAAIDPDAALHAVCQV QPSATLEAEQPRVSGLVLFRQIRPGTLLEAFFHLEGFQDEPNGTNHAIHVHQFGDLSQGCDSTGPHYNPM SMPHPQHPGDFGNFPVRSGQVWKHRYDLAASLTGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRL ACCVVGLCGPGPWARKAQEHAERRKRRLESECKAGAAARERG >XP_023109018.1 extracellular superoxide dismutase [Cu-Zn] [Felis catus] MLAPALLCAYLLLAARASRAWSDPDPEEPGSSTAAQIRDMHEKVTAIWQEMTQRQAAGDRPDAALHAACR VQPSATLDAAQPRVSGLVLFRQQVPGARLEAFFDLEGFPAEPNNSSRAIHVHQFGDLSQGCDSTGAHYNP RAVPHPQHPGDFGNFAVRDGRLWKYRGGLAASLFGPHSIVGRAVVVHAGEDDLGRGGNVASVENGNAGPR LACCVVGVCGPLPWARQAQEHAERRKRRRDSECKAV >XP_040191114.1 extracellular superoxide dismutase [Cu-Zn] [Rana temporaria] MMLLAVILTISISFGATAEEGQTCQSEITTILQKVDEIYDAIYNGVQNNEDKAIYATCKLQPSPKLDDDE IKIMGQVLFKQIYPNGELEAVFSIEGFPQDVNQSVRAIHIHDFGDISNGCDSAGGHYNPFSVDHPNHPGD FGNFRVRNGKIQQYLMNLGAKMFGPVSIIGRSIVVHKMADDLGKGDNRASLENGNAGARLACCVIGTTNK NGWEKYMEENAKLKTPRVARRGNMQQKKPK
Mafft alignment of selected proteins >sp|P08294|SODE_HUMAN Extracellular superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD3 PE=1 SV=2 ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALLCSCLLLAA GASDAWTGEDSAEPN---------------SDSAEWIRDMYAKVTEIWQE-VMQRR---- -----DDDGALHAACQVQPSATLDAA-QPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPN -SSSRAIHVHQFGDL-SQGCESTGPHYNPLAVPHP------QHPGDFGNFAV-RDGSLWR YRAGLAASLAGPHSIVGRAVVVHAGEDDLGRG---GNQASVENGNAGRRLACCVVGVCGP GLWERQAREHSERKKRRRESECKAA---------- >tr|E9QIM2|E9QIM2_DANRE Superoxide dismutase [Cu-Zn] OS=Danio rerio OX=7955 GN=sod3b PE=3 SV=1 ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MI--RFNILPLLAF- ------------------------------------LLSCHVLFCGSGSG-L---AY--- ----ASNSDSLQAVCRMQPNTRLEPG-MPRVYGHILFRQSGPKEKLSVTFRLYGLPADS- -QQPRAMHIHEYGDL-SRGCDSTGGHYNPLNVNHP------QHPGDFGNFVP-VNKKIRQ SLES-PATLFGKLSIVGRSVVIHEGKDDLGRG---GNVGSLLNGNAGGRLACCVIGLRNP QN--------------------------------- >NP_035565.1 extracellular superoxide dismutase [Cu-Zn] precursor [Mus musculus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--AFLFYGLLLAA CGSV--TMSNPGESSFDLADRLDPVEKIDRLDLVEKIGDTHAKVLEIWME-LGRRREV-- ------DAAEMHAICRVQPSATLPPD-QPQITGLVLFRQLGPGSRLEAYFSLEGFPAEQN -ASNRAIHVHEFGDL-SQGCDSTGPHYNPMEVPHP------QHPGDFGNFVV-RNGQLWR HRVGLTASLAGPHAILGRSVVVHAGEDDLGKG---GNQASLQNGNAGRRLACCVVGTSSS AAWESQTK---ERKKRRRESECKTT---------- >XP_038068816.1 superoxide dismutase [Cu-Zn]-like [Patiria miniata] MAVR-------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------MSAPRHLLVIALLSC GFTHAADRLPLSAQL---------------IRMQSQIDILRRDVDQLLGE-LHRTHGPEP PNLNLEGDGNVYAHCRMVPNGIYDPDTYEPIVGDIDMRQRAVGGPMDVEVFLYGFMTP-- -KSVHALHVHTYGDL-RHGCGSAGSHYNPGGNNHSAPYDKDRHMGDWGNIQVDDFGMVEE TFTDKVATLVGPNSILGRTIVIHIGEDDLGKG---GTADSKKTGNAGGRLGCCVIGRSDG SAWIGY----------------------------- >KAB0342939.1 hypothetical protein FD754_019865 [Muntiacus muntjak] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALLCACLLLVA CDSGASADQLLHQM-----------------IMEEQIRDMHTKVTEIWQETVMQRRAT-- ---AIDPDAALHAVCRVLPSATLEAE-QPRVSGLVLFRQIRPGTLLEAFFHLEGFQNEPN -GTSHAIHVHEFGDL-SQGCDSTGPHYNPMSVPHP------QHPGDFGNFAV-RNGQVWK HRYDLAASLTGPHSIAGRAVVVHAGEDDMGRG---GNQASLENGNAGRRLACCVVGLCGP GPWARKAQEHAERRKRRLESECKAGAAARERA--- >XP_043294215.1 extracellular superoxide dismutase [Cu-Zn] [Cervus canadensis] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALLCAYLLLVA CDSAASTDQLLHQM-----------------IMEEQIRDMHTKVTEIWQETVTQRRAA-- ---AIDPDAALHAVCRVQPSATLEAE-QPQVSGLVLFRQIRPGTLLEAFFHLEGFQDEPN -GTSHAIHVHQFGDL-SQGCDSTGPHYNPMSVPHP------QHPGDFGNFAV-RNGQVWK HRYDLAASLTGPHSIAGRAVVVHAGEDDLGRG---GNQASLENGNAGRRLACCVVGLCGP GPWARKAQEHAERRKRRLESECKARARRESEPKAL >XP_018098563.1 extracellular superoxide dismutase [Cu-Zn] [Xenopus laevis] MNH--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------LF---------YMAE VFTICAVLSARSEIV--------------KPVEEELLADTNKKVNELWLN-FLNMKP--- ----VDNDGIAYATCSVSPSSKLESS-EIKVMGLVLFKQVFPSGRLEAIFDLEGFPTDAN -QSTRAIHIHKYGDL-TDGCDSAGGHYNPNSVDHP------HHPGDFGNFRV-RDGKIQK FLANLDATLFGPSSVIGRSIVVHKQADDLGKG---NNQASLENGNAGKRLACCIIGSSSK NNWEKYIQDSAAPRSLRFSRRVKKG---------- >XP_030247694.1 extracellular superoxide dismutase [Cu-Zn] [Sparus aurata] MRPHG------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------SM--SILGALFVL-- ------------------------------------LAGGQQCVSATTDT-LAPPEV--- ----SQHNGTLYAACKMRPSTSLAEG-LPKVYGQALFKQDYPQGKLKVLLRFNGFPTEGD -PQPRAVHIHQYGDL-SQGCDSTGGHYNPHGVPHP------NHPGDFGNFEA-QQGKINA MMES-EATMFGGMSVIGRAVVIHEKIDDLGRG---GDAGSLLHGNAGRRLACCIIGISSP KLWNTHQKLYTRRLRSN------------------ >XP_004084336.2 extracellular superoxide dismutase [Cu-Zn] [Oryzias latipes] MSLHR------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------SV--RVLEMAFLVW- ------------------------------------LACSQQCFSTHTDH-LLPPEF--- ----SQYNGTLYAACKVSPSTSLPDD-LPKVYGQALFKQDHGQGKLQVLLQLAGFPEDES -PQSRAIHIHQYGDL-SQGCISTGGHYNPYGVDHP------NHPGDFGNFVA-HEGRISE QIES-EATLFGGLSVLGRAVVVHETIDDLGQG---GDVGSLLHGNAGRRLACCVIGMSSS DLWEEQQKLQSS----------------------- >XP_015799267.1 PREDICTED: extracellular superoxide dismutase [Cu-Zn] [Nothobranchius furzeri] MHIHG------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------SV--RGLQTALLV-- ------------------------------------LLAGHQCVSGDTDI-LLPPEF--- ----SQHNGTLYASCKMRPSSSLPED-LPKVYGQVLFKQEL-QGKLQVLFQFSGFPATED LPQPRAVHIHQYGDL-SQGCDSTGGHYNPNGVNHP------NHPGDFGNFVP-QQGKVSD QRES-EATLFGGLSVIGRAVVVHEGVDDLGLG---GDTGSLMHGNAGPRLACCVIGMSSS SLWNTQAEAVYKTAEEILDPQ-------------- >CAE1264788.1 SOD1 [Sepia pharaonis] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SIKAVCVMKGDR--------DVSGVIHFTQESPTKPVKLTGEIRGMAD--- --GKHGFHIHEFGDN-TNGCTSAGPHFNPDNKEHGAPTDENRHVGDLGNVDS-SGGIANV NIEDKIINLTGPHSIIGRTVVVHADIDDLGKG---GHELSKTTGNAGSRLACGVIGITK- ----------------------------------- >XP_030829251.1 superoxide dismutase [Cu-Zn]-like isoform X2 [Strongylocentrotus purpuratus] MQL--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------LL--ALLSLTALITS ------------------------------------------------------------ ----SSAVTVNFASCRLTKSE------NGEVVGRVDLREQSDTNVLQLRLQVDGAKLTLA ANSKHGFHVHTYGNI-SGSCSTTGGHYNPDGVDHASPTSAQRHVGDLGNVQADASGNIDV SFNDTYASLTGTKAIMGRAFVLHGGEDDIGLG---GNAGSLASGNAGPRLACCVIGWATG TDWVY------------------------------ >XP_039262007.1 superoxide dismutase [Cu-Zn]-like [Styela clava] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------ASPKTAVCILEGST-------EGVEGIINFKDMG-DGTCSIKGEITGLKT--- --GQHGFHVHQYGDY-TNGCTSTGGHFNPYNKEHGGPDDTERHVGDLGNIMVDESGKATI DITDKQVKLDGEFSVVGRAIVVHADVDDLGRG---GFPDSKTTGHAGGRLACGVIGLSPA K---------------------------------- >XP_031572834.1 superoxide dismutase [Cu-Zn]-like isoform X2 [Actinia tenebrosa] MK---------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------HI--AVLSILLVYAS V----------------------------------------------------------- ----VEVSAQVTVMCXMEPNRVPPSNVKSTVTGTVKLSQQSSSAQTKFTVKLNGLPP--- -YSVHGFHVHNYGDIXSNGCQSCGSHYNPFNATHGGPRDRIRHVGDLGNLMSDDNGRIEA EFTDSLVSLQGNYSVIGRSIVLHAKRDDLGRGKGAARKESLKTGNAGARLGCCAIVYAAP PAPSN------------------------------ >NP_001171498.1 superoxide dismutase 1 [Apis mellifera] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------TKAVCVLQG----------EVKGTIFFEQPESTNSVKVTGQVTGLKK--- --GLHGFHVHEFGDN-TNGCTSAGAHFNPLGKDHGGPDSDIRHVGDLGNIEADASGVANV NITDKTIQLQGPHSVIGRTLVVHADPDDLGKG---GVELSKTTGNAGARLACGVIGITKV ----------------------------------- >NP_001021956.1 Superoxide dismutase [Cu-Zn] [Caenorhabditis elegans] M----------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------FM--NLLT------- ---------------------------------------------QVSNA-IFPQVE--- ----AAQKMSNRAVAVLRG---------ETVTGTIWITQKSENDQAVIEGEIKGLTP--- --GLHGFHVHQYGDS-TNGCISAGPHFNPFGKTHGGPKSEIRHVGDLGNVEAGADGVAKI KLTDTLVTLYGPNTVVGRSMVVHAGQDDLGEGVGDKAEESKKTGNAGARAACGVIALAAP Q---------------------------------- >AAD14963.2 slow superoxide dismutase, partial [Drosophila melanogaster] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------VING----------DAKGTVFFEQESSGTPVKVSGEVCGLAK--- --GLHGFHVHEFGDN-TNGCMSSGPHFNPYGKEHGAPVDENRHLGDLGNIEATGDCPTKV KITDSKITLFGADSIIGRTVVVHADADDLGQG---GHELSKSTGNAGARIGCGVIGIAKV ----------------------------------- >NP_037012.1 extracellular superoxide dismutase [Cu-Zn] precursor [Rattus norvegicus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MV--AFLFCNLLLVA CGSVTWTMSDTGESGVDLA---------DRLDLVEKIGDTHSKDLEIWME-LGKQREA-- ------DAREMHAVCRVQPSAMLPPD-QPQITGLVLFRQLGPSSRLEASFNLEGFPAEQN -TSNHAIHVHEFGDL-SQGCESTGPHYNPLGVPHP------QHPGDFGNFVV-RDGRLWK HRMGLATSLAGPHSILGRAVVVHAGEDDLGKG---GNQASVQNGNAGRRLACCVVGTSNS EAWESQTK---ERKKRRRESECKTT---------- >XP_040525137.1 extracellular superoxide dismutase [Cu-Zn] [Gallus gallus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--LLLS---LVT- GLALSASDVVTETGA---------------DPSSALLHDIQRKVNDLWQS-LLYPVMA-- ---DNETDGLTYATCEVKPSSKIDAD-KPQVTGQVLFRQHYSQGKLEAIFHLDGFPLDNN -QSGRAIHIHELGDL-SDGCNSAGGHYNPFGVNHP------RHPGDFGNFSP-KDGKIRK YKPNLFATMFGPYSILGRSVVIHEQEDDMGKG---NNKASLENGNAGKRLACCVIGICNK NLWEEKQSEAMDRKKRWRRTRLS------------ >XP_009445714.1 extracellular superoxide dismutase [Cu-Zn] [Pan troglodytes] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALLCSCLLLAA GASDAWTGEDSAEPN---------------SDSAEWIRDMYAKVTEIWQE-VMQRR---- -----DDDGALHAACQVQPSATLDAA-QPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPN -SSSRAIHVHQFGDL-SQGCESTGPHYNPLAVPHP------QHPGDFGNFAV-RDGSLWR YRAGLAASLAGPHSIVGRAVVVHAGEDDLGRG---GNQASVENGNAGRRLACCVVGVCGP GLWERQAREHSERKKRRRESECKAA---------- >XP_545973.4 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Canis lupus familiaris] MACLP---------------------CSDSDRDPLPGA---------------------- ----------------------------------GLPARPQTAQPK-------------- -------------ESARIPGCCSLLLRRKA--LSEELGR-CPPPAMLAPALLCAHLLLAA PASRAWPGAAPDEPEPQPQ--PQPEPEPGPGAVAAQLSDMHDKVTAIWQQ-LTQRAAE-- ---PGAPGSALHAACRVQPSASLDPA-QPRVSGLVLFRQPAPGAPLEAFFHLDGFPAERN -GSRRAIHVHRFGDL-SPGCEAAGPHYNPRAAPHP------HHPGDFGNFAV-RDGRVRK HRGGLAASLAGPHSIVGRAVVVHAGEDDLGRG---GDPASLDHGNAGRRLACCVVGVCGP LPWARAAREHAERRKRRRDSDCQAA---------- >XP_024849041.1 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Bos taurus] MGHFREHI------------------ASARSSGSKPYAASLR------------------ ----------------------------------GCRKRVA------------------- -----------------GDEGAEMLRRRRSGRATRASLR-CSTLAML--ALLCASVVLVA ---YASADQIQQQMG---------------SNTEEQIRDMHAKVTEIWQE-MMQRQAA-- ---AIDPDAALHAVCRVLPSATLEAE-QPRVSGLVLFRQLRPGALLEAFFHLEGFPNEPN -GTNRAIHVHQFGDL-SQGCDSTGPHYNPMSVPHP------QHPGDFGNFAV-RDGQVWK YRSGLAASLTGPHSIAGRAVVVHAGEDDMGRG---GNQASLENGNAGRRLACCVVGLCGP GPWARQTQEHAERKKRRRESECKAV---------- >XP_020956182.1 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Sus scrofa] MPFFP---------------------REDHAPEAAPRATNSP------------------ ----------------------------------GFCQPPSCSDDDGQAG---------- -------------AAPHFPGGKALL---------EELER-CPTPAML--TLLCAYLLLAP GASDALTHVDVERPG---------------SHMEEQIRDMQAKVTEIWQE-LTQQRAA-- ---GGGQEAALHATCSMQPSVLLDAA-QPQVTGLVLFRQLRPGALLEAFFHLKGFPAEPN -STSRAIHVHQFGDL-SQGCDSTGPHYNPLEVPHP------QHPGDFGNFAV-RDGQIWR YRSSPGASLFGPHSIAGRAVVVHAGEDDLGRG---GNQASLENGNAGRRLACCVVALCGP GPWAHQAQEHAEHRKRRRASECKAS---------- >NP_001076101.1 extracellular superoxide dismutase [Cu-Zn] precursor [Oryctolagus cuniculus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALVCSCLLLAA LPADTWSGPAAVELG---------------SDTVEQIRDTHAKVTEIWQA-LTQQRAA-- ---QGEPAGALHAVCRVQPSATLDAA-QPRVSGLVVFRQLGPGAQLEAFFDLEGFPVEAN -LSSRAIHVHQFGDL-SQGCDSTGAHYNPLAVQHP------QHPGDFGNFAV-RDGRLWK YRSGLAASLAGPHSIVGRAVVVHAGEDDLGRG---GNAASVENGNAGPRLACCVVGASGP APWARQAQEHAERKKRRRESECKAA---------- >XP_009238123.2 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Pongo abelii] MSV--------------------------------------------------------- ----------------------------------G------------------------- ----------------------------------EDGGRGCPTPAML--ALLCSCLLLAA GASDAWTGEDSVEPN---------------SDSAEWIRDMYAKVTEIWQE-VMQRR---- -----DDDGALHAACQVQPSATLDAT-QPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPN -SSSRAIHVHQFGDL-SQGCESTGPHYNPLAVPHP------RHPGDFGNFAV-RDGSLWK YRAGLAASLAGPHSIVGRAVVVHAGEDDLGRG---GNQASVENGNAGRRLACCVVGVCGP GLWERQAREHSERKKRRRESECKAA---------- >XP_010708631.2 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Meleagris gallopavo] MKKWKYKP---------------LCDVTTSTRAPSPALMLLAVQKGTQCHTHMDIEGKAA LTLGNFFSLCFGQFPPQAHRARISSLACPRQTLGSLCPSHSTAGDPSPVRRYPTHKQRSR SHQPHAAPVVSDPTSPRGSGVAGLLPSS----AAGRFCR-LSVTRML--LLLS---LVT- GLALSAAGVVTETGA---------------DPSCASLHDVQRKVNDLWQS-LLYPVMA-- ---DNETDGLTYATCEMKPSSKIGAD-KPQVTGQVLFRQHYSQGRLEAIFHLDGFPLDNN -QSGRAIHIHELGDL-SNGCDSTGGHYNPFRVNHP------RHPGDFGNFSP-KDGKIRK YKSNLFATMFGPYSILGRAIVIHEQEDDMGKG---NNKASLENGNAGKRLACCVIGICNK NLWEEKQFEATDKKKRWLRTRLS------------ >NP_001272604.1 extracellular superoxide dismutase [Cu-Zn] precursor [Capra hircus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MP--ALLCASLLLVA CASAASADQVQQQMG---------------SNTEEQIRDMHAKVTEIWQE-MMQRQAA-- ---AIDPDAALHAVCRVLPSATLEAE-QPRVSGLVLFRQLRPGALLEAFFHLEGFPNEPN -GTSRAIHVHQFGDL-SQGCDSTGPHYNPMSVLHP------QHPGDFGNFAV-RDGQVWK YRSNLAASLTGPHSIAGRAVVVHAGEDDLXRG---GNQASLENGNAGRRLACCVVGLCGP GPWAHQAQENAERKKRRRESECKDV---------- >XP_008950433.1 extracellular superoxide dismutase [Cu-Zn] [Pan paniscus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALLCSCLLLAA GASDAWTGEDSAEPN---------------SDSAEWIRDMYAKVTEIWQE-VMQRR---- -----DDDGALHAACQVQPSATLDAA-QPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPN -SSSRAIHVHQFGDL-SQGCESTGPHYNPLAVPHP------QHPGDFGNFAV-RDGSLWR YRAGLAASLAGPHSIVGRAVVVHAGEDDLGRG---GNQASVENGNAGRRLACCVVGVCGP GLWERQAREHSERKKRRRESECKAA---------- >XP_014951904.2 extracellular superoxide dismutase [Cu-Zn] isoform X2 [Ovis aries] MSLFLAPLSFAEWLTPTQTISEKSCWGQSGAVGRPPRAGSLKQALGTE------------ LPFFNGLLLFFSQ------KRNFSSVTTPP---GGCPAQTQTAREL-------------- -------------PAFLCPAGEVLLLGSQVRERSLKSWR-GARLAMP--ALLCASLLLVA CALAASADQVQQQMG---------------SNTEEQIRDMHAKVTEIWQE-MMQRQAA-- ---AIDPDAALHAVCRVLPSATLEAE-QPRVSGLVLFRQLRPGALLEAFFHLEGFPNEPN -GTSRAIHVHQFGDL-SQGCDSTGPHYNPMSVLHP------QHPGDFGNFAV-RDGQVWK YRSNLAASLTGPHSIAGRAVVVHAGEDDLGRG---GNQASLENGNAGRRLACCVVGLCGP GPWAHQAQENAERKKRRRESECKAV---------- >XP_004038545.3 extracellular superoxide dismutase [Cu-Zn] [Gorilla gorilla gorilla] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALLCSCLLLAA GASDAWTGEDSAEPN---------------SDSAEWIRDMYAKVTEIWQE-VMQRR---- -----DDDGALHAACQVQPSATLDAA-QPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPN -SSSRAIHVHQFGDL-SQGCESTGPHYNPLAVPHP------QHPGDFGNFAV-RDGSLWK YRAGLAASLAGPHSIVGRAVVVHAGEDDLGRG---GNQASVENGNAGRRLACCVVGVCGP GLWERQAREHSERKKRRRQSECKAA---------- >XP_005501341.1 extracellular superoxide dismutase [Cu-Zn] [Columba livia] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--LLLS---LVA- GLALSASGGVTDKES---------------DSSQEPFQDIETKVNDLWQS-LLYPVAP-- ---GNESDRMIYATCEMKPSSKIDAD-KPQVTGQVLFRQYYSYGRLEAIFYLDGFPLDNN -QSGRAIHIHELGDL-SNGCDATGGHYNPFRVNHP------RHPGDFGNFFP-KEGKIRK YKTNLFATMFGPYSIMGRSVVIHEQEDDMGKG---NNKASLENGNAGKRLACCVIGICNK NLWEEKLSEVTDKKKRGLNKRTQNQV--------- >XP_006024876.1 extracellular superoxide dismutase [Cu-Zn] [Alligator sinensis] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MF--LSLC---LVSV GLFLSLPGVVSGELEP-------------VPETEGLFQELRKKVNDLWQN-LLYPQFI-- ----RDSDWTAYATCEMKPSSKLDAD-KPQVTGQILFKQSYPIGKLEAFFDLDGFPSENN -QLGRAIHIHKFGDL-SDGCNTTGGHYNPFNVNHP------HHPGDFGNFYS-KEGKIRK YKSNLSATLFGPYTIMGRSVVIHEQEDDMGKG---NNKASLENGNAGRRLACCVIGICDK NMWENKFSKFVERRKRGSQNEHRSRPS-------- >XP_006260489.1 PREDICTED: extracellular superoxide dismutase [Cu-Zn] [Alligator mississippiensis] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MF--LSLC---LVSV GLFLSLPGVVSGELEP-------------VPETEGLFQELRKKVNDLWQN-LLYPQFI-- ----RDSDWTAYATCEMKPSSKLDAD-KPQVTGQILFKQSYPIGKLEAFFDLDGFPSENN -QLGRAIHIHKFGDL-SDGCNTTGGHYNPFNVNHP------HHPGDFGNFYS-KEGKIRK YKSNLSATLFGPYTIMGRSVVIHEQEDDMGKG---NNKASLENGNAGRRLACCVIGICDK NMWENKFSKFVERKKRGSQNEHRSRPN-------- >XP_020753289.1 extracellular superoxide dismutase [Cu-Zn] [Odocoileus virginianus texanus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ML--ALLCVYLLLVA CDSAASADQFLHQMY---------------SFMEEQIRDMHTKVTEIWQETVMQRRAA-- ---AIDPDAALHAVCQVQPSATLEAE-QPRVSGLVLFRQIRPGTLLEAFFHLEGFQDEPN -GTNHAIHVHQFGDL-SQGCDSTGPHYNPMSMPHP------QHPGDFGNFPV-RSGQVWK HRYDLAASLTGPHSIAGRAVVVHAGEDDLGRG---GNQASLENGNAGRRLACCVVGLCGP GPWARKAQEHAERRKRRLESECKAGAAARERG--- >XP_023109018.1 extracellular superoxide dismutase [Cu-Zn] [Felis catus] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MLAPALLCAYLLLAA RASRAWSDPDPEEPG---------------SSTAAQIRDMHEKVTAIWQE-MTQRQAA-- ---GDRPDAALHAACRVQPSATLDAA-QPRVSGLVLFRQQVPGARLEAFFDLEGFPAEPN -NSSRAIHVHQFGDL-SQGCDSTGAHYNPRAVPHP------QHPGDFGNFAV-RDGRLWK YRGGLAASLFGPHSIVGRAVVVHAGEDDLGRG---GNVASVENGNAGPRLACCVVGVCGP LPWARQAQEHAERRKRRRDSECKAV---------- >XP_040191114.1 extracellular superoxide dismutase [Cu-Zn] [Rana temporaria] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MM---------LLAV ILTISISFGATAEEG---------------QTCQSEITTILQKVDEIYDA-IYNGVQ--- ----NNEDKAIYATCKLQPSPKLDDD-EIKIMGQVLFKQIYPNGELEAVFSIEGFPQDVN -QSVRAIHIHDFGDI-SNGCDSAGGHYNPFSVDHP------NHPGDFGNFRV-RNGKIQQ YLMNLGAKMFGPVSIIGRSIVVHKMADDLGKG---DNRASLENGNAGARLACCVIGTTNK NGWEKYMEENAKLKTPRVARRGNMQQKKPK-----
BMGE Cleaned alignment of selected proteins >sp|P08294|SODE_HUMAN Extracellular superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD3 PE=1 SV=2 CLLLAAGAAEWIRDMAKVTEIWQEVMQRR--DGALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFALEGFPTSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGNFAVAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA >tr|E9QIM2|E9QIM2_DANRE Superoxide dismutase [Cu-Zn] OS=Danio rerio OX=7955 GN=sod3b PE=3 SV=1 PLLAF------LLSCVLFCGSGSGL---AY-SDSLQAVCRMQPNTRLEPGMPRVYGHILFRQSGPKEKLSVTRLYGLPAPRAMHIHEYGDLSRGCDSTGGHYNPLNVNHPQHPGDFGNFVPES-PATLFGKLSIVGRSVVIHEGKDDLGRGGNVGSLLNGNAGGRLACCVIGLRNPQN----------------------- >NP_035565.1 extracellular superoxide dismutase [Cu-Zn] precursor [Mus musculus] GLLLAACGVEKIGDTAKVLEIWMELGRRREVAAEMHAICRVQPSATLPPDQPQITGLVLFRQLGPGSRLEAYSLEGFPANRAIHVHEFGDLSQGCDSTGPHYNPMEVPHPQHPGDFGNFVVVGLTASLAGPHAILGRSVVVHAGEDDLGKGGNQASLQNGNAGRRLACCVVGTSSSAAWESQTK---ERKKRRRESECKTT >XP_038068816.1 superoxide dismutase [Cu-Zn]-like [Patiria miniata] IALLSCGFQSQIDILRDVDQLLGELHRTHGPDGNVYAHCRMVPNGIYDPDYEPIVGDIDMRQRAVGGPMDVEFLYGFMTVHALHVHTYGDLRHGCGSAGSHYNPGGNNHSRHMGDWGNIQVTDKVATLVGPNSILGRTIVIHIGEDDLGKGGTADSKKTGNAGGRLGCCVIGRSDGSAWIGY------------------- >KAB0342939.1 hypothetical protein FD754_019865 [Muntiacus muntjak] CLLLVACDEEQIRDMTKVTEIWQEVMQRRATDAALHAVCRVLPSATLEAEQPRVSGLVLFRQIRPGTLLEAFHLEGFQNSHAIHVHEFGDLSQGCDSTGPHYNPMSVPHPQHPGDFGNFAVYDLAASLTGPHSIAGRAVVVHAGEDDMGRGGNQASLENGNAGRRLACCVVGLCGPGPWARKAQEHAERRKRRLESECKAG >XP_043294215.1 extracellular superoxide dismutase [Cu-Zn] [Cervus canadensis] YLLLVACDEEQIRDMTKVTEIWQEVTQRRAADAALHAVCRVQPSATLEAEQPQVSGLVLFRQIRPGTLLEAFHLEGFQDSHAIHVHQFGDLSQGCDSTGPHYNPMSVPHPQHPGDFGNFAVYDLAASLTGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRLACCVVGLCGPGPWARKAQEHAERRKRRLESECKAR >XP_018098563.1 extracellular superoxide dismutase [Cu-Zn] [Xenopus laevis] --YMAEVFEELLADTKKVNELWLNFLNMKP-DGIAYATCSVSPSSKLESSEIKVMGLVLFKQVFPSGRLEAIDLEGFPTTRAIHIHKYGDLTDGCDSAGGHYNPNSVDHPHHPGDFGNFRVANLDATLFGPSSVIGRSIVVHKQADDLGKGNNQASLENGNAGKRLACCIIGSSSKNNWEKYIQDSAAPRSLRFSRRVKKG >XP_030247694.1 extracellular superoxide dismutase [Cu-Zn] [Sparus aurata] LFVL-------LAGGQCVSATTDTLAPPEV-NGTLYAACKMRPSTSLAEGLPKVYGQALFKQDYPQGKLKVLRFNGFPTPRAVHIHQYGDLSQGCDSTGGHYNPHGVPHPNHPGDFGNFEAES-EATMFGGMSVIGRAVVIHEKIDDLGRGGDAGSLLHGNAGRRLACCIIGISSPKLWNTHQKLYTRRLRSN-------- >XP_004084336.2 extracellular superoxide dismutase [Cu-Zn] [Oryzias latipes] AFLVW------LACSQCFSTHTDHLLPPEF-NGTLYAACKVSPSTSLPDDLPKVYGQALFKQDHGQGKLQVLQLAGFPESRAIHIHQYGDLSQGCISTGGHYNPYGVDHPNHPGDFGNFVAES-EATLFGGLSVLGRAVVVHETIDDLGQGGDVGSLLHGNAGRRLACCVIGMSSSDLWEEQQKLQSS------------- >XP_015799267.1 PREDICTED: extracellular superoxide dismutase [Cu-Zn] [Nothobranchius furzeri] ALLV-------LLAGQCVSGDTDILLPPEF-NGTLYASCKMRPSSSLPEDLPKVYGQVLFKQEL-QGKLQVLQFSGFPAPRAVHIHQYGDLSQGCDSTGGHYNPNGVNHPNHPGDFGNFVPES-EATLFGGLSVIGRAVVVHEGVDDLGLGGDTGSLMHGNAGPRLACCVIGMSSSSLWNTQAEAVYKTAEEILDPQ---- >CAE1264788.1 SOD1 [Sepia pharaonis] ---------------------------------SIKAVCVMKGDR-------DVSGVIHFTQESPTKPVKLTEIRGMADKHGFHIHEFGDNTNGCTSAGPHFNPDNKEHGRHVGDLGNVDSEDKIINLTGPHSIIGRTVVVHADIDDLGKGGHELSKTTGNAGSRLACGVIGITK-------------------------- >XP_030829251.1 superoxide dismutase [Cu-Zn]-like isoform X2 [Strongylocentrotus purpuratus] TALITS-------------------------VTVNFASCRLTKSE-----NGEVVGRVDLREQSDTNVLQLRQVDGAKLKHGFHVHTYGNISGSCSTTGGHYNPDGVDHARHVGDLGNVQANDTYASLTGTKAIMGRAFVLHGGEDDIGLGGNAGSLASGNAGPRLACCVIGWATGTDWVY-------------------- >XP_039262007.1 superoxide dismutase [Cu-Zn]-like [Styela clava] -------------------------------ASPKTAVCILEGST------EGVEGIINFKDMG-DGTCSIKEITGLKTQHGFHVHQYGDYTNGCTSTGGHFNPYNKEHGRHVGDLGNIMVTDKQVKLDGEFSVVGRAIVVHADVDDLGRGGFPDSKTTGHAGGRLACGVIGLSPAK------------------------ >XP_031572834.1 superoxide dismutase [Cu-Zn]-like isoform X2 [Actinia tenebrosa] LLVYASV------------------------SAQVTVMCXMEPNRVPPSNKSTVTGTVKLSQQSSSAQTKFTKLNGLPPVHGFHVHNYGDISNGCQSCGSHYNPFNATHGRHVGDLGNLMSTDSLVSLQGNYSVIGRSIVLHAKRDDLGRGARKESLKTGNAGARLGCCAIVYAAPPAPSN-------------------- >NP_001171498.1 superoxide dismutase 1 [Apis mellifera] ----------------------------------TKAVCVLQG---------EVKGTIFFEQPESTNSVKVTQVTGLKKLHGFHVHEFGDNTNGCTSAGAHFNPLGKDHGRHVGDLGNIEATDKTIQLQGPHSVIGRTLVVHADPDDLGKGGVELSKTTGNAGARLACGVIGITKV------------------------- >NP_001021956.1 Superoxide dismutase [Cu-Zn] [Caenorhabditis elegans] -------------------QVSNAIFPQVE-KMSNRAVAVLRG--------ETVTGTIWITQKSENDQAVIEEIKGLTPLHGFHVHQYGDSTNGCISAGPHFNPFGKTHGRHVGDLGNVEATDTLVTLYGPNTVVGRSMVVHAGQDDLGEGKAEESKKTGNAGARAACGVIALAAPQ------------------------ >AAD14963.2 slow superoxide dismutase, partial [Drosophila melanogaster] ---------------------------------------VING---------DAKGTVFFEQESSGTPVKVSEVCGLAKLHGFHVHEFGDNTNGCMSSGPHFNPYGKEHGRHLGDLGNIEATDSKITLFGADSIIGRTVVVHADADDLGQGGHELSKSTGNAGARIGCGVIGIAKV------------------------- >NP_037012.1 extracellular superoxide dismutase [Cu-Zn] precursor [Rattus norvegicus] NLLLVACGVEKIGDTSKDLEIWMELGKQREAAREMHAVCRVQPSAMLPPDQPQITGLVLFRQLGPSSRLEASNLEGFPANHAIHVHEFGDLSQGCESTGPHYNPLGVPHPQHPGDFGNFVVMGLATSLAGPHSILGRAVVVHAGEDDLGKGGNQASVQNGNAGRRLACCVVGTSNSEAWESQTK---ERKKRRRESECKTT >XP_040525137.1 extracellular superoxide dismutase [Cu-Zn] [Gallus gallus] --LVT-GLSALLHDIRKVNDLWQSLLYPVMADGLTYATCEVKPSSKIDADKPQVTGQVLFRQHYSQGKLEAIHLDGFPLGRAIHIHELGDLSDGCNSAGGHYNPFGVNHPRHPGDFGNFSPPNLFATMFGPYSILGRSVVIHEQEDDMGKGNNKASLENGNAGKRLACCVIGICNKNLWEEKQSEAMDRKKRWRRTRLS-- >XP_009445714.1 extracellular superoxide dismutase [Cu-Zn] [Pan troglodytes] CLLLAAGAAEWIRDMAKVTEIWQEVMQRR--DGALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFALEGFPTSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGNFAVAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA >XP_545973.4 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Canis lupus familiaris] HLLLAAPAAAQLSDMDKVTAIWQQLTQRAAEGSALHAACRVQPSASLDPAQPRVSGLVLFRQPAPGAPLEAFHLDGFPARRAIHVHRFGDLSPGCEAAGPHYNPRAAPHPHHPGDFGNFAVGGLAASLAGPHSIVGRAVVVHAGEDDLGRGGDPASLDHGNAGRRLACCVVGVCGPLPWARAAREHAERRKRRRDSDCQAA >XP_024849041.1 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Bos taurus] SVVLVA--EEQIRDMAKVTEIWQEMMQRQAADAALHAVCRVLPSATLEAEQPRVSGLVLFRQLRPGALLEAFHLEGFPNNRAIHVHQFGDLSQGCDSTGPHYNPMSVPHPQHPGDFGNFAVSGLAASLTGPHSIAGRAVVVHAGEDDMGRGGNQASLENGNAGRRLACCVVGLCGPGPWARQTQEHAERKKRRRESECKAV >XP_020956182.1 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Sus scrofa] YLLLAPGAEEQIRDMAKVTEIWQELTQQRAAEAALHATCSMQPSVLLDAAQPQVTGLVLFRQLRPGALLEAFHLKGFPASRAIHVHQFGDLSQGCDSTGPHYNPLEVPHPQHPGDFGNFAVSSPGASLFGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRLACCVVALCGPGPWAHQAQEHAEHRKRRRASECKAS >NP_001076101.1 extracellular superoxide dismutase [Cu-Zn] precursor [Oryctolagus cuniculus] CLLLAALPVEQIRDTAKVTEIWQALTQQRAAAGALHAVCRVQPSATLDAAQPRVSGLVVFRQLGPGAQLEAFDLEGFPVSRAIHVHQFGDLSQGCDSTGAHYNPLAVQHPQHPGDFGNFAVSGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNAASVENGNAGPRLACCVVGASGPAPWARQAQEHAERKKRRRESECKAA >XP_009238123.2 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Pongo abelii] CLLLAAGAAEWIRDMAKVTEIWQEVMQRR--DGALHAACQVQPSATLDATQPRVTGVVLFRQLAPRAKLDAFALEGFPTSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPRHPGDFGNFAVAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA >XP_010708631.2 extracellular superoxide dismutase [Cu-Zn] isoform X1 [Meleagris gallopavo] --LVT-GLCASLHDVRKVNDLWQSLLYPVMADGLTYATCEMKPSSKIGADKPQVTGQVLFRQHYSQGRLEAIHLDGFPLGRAIHIHELGDLSNGCDSTGGHYNPFRVNHPRHPGDFGNFSPSNLFATMFGPYSILGRAIVIHEQEDDMGKGNNKASLENGNAGKRLACCVIGICNKNLWEEKQFEATDKKKRWLRTRLS-- >NP_001272604.1 extracellular superoxide dismutase [Cu-Zn] precursor [Capra hircus] SLLLVACAEEQIRDMAKVTEIWQEMMQRQAADAALHAVCRVLPSATLEAEQPRVSGLVLFRQLRPGALLEAFHLEGFPNSRAIHVHQFGDLSQGCDSTGPHYNPMSVLHPQHPGDFGNFAVSNLAASLTGPHSIAGRAVVVHAGEDDLXRGGNQASLENGNAGRRLACCVVGLCGPGPWAHQAQENAERKKRRRESECKDV >XP_008950433.1 extracellular superoxide dismutase [Cu-Zn] [Pan paniscus] CLLLAAGAAEWIRDMAKVTEIWQEVMQRR--DGALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFALEGFPTSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGNFAVAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA >XP_014951904.2 extracellular superoxide dismutase [Cu-Zn] isoform X2 [Ovis aries] SLLLVACAEEQIRDMAKVTEIWQEMMQRQAADAALHAVCRVLPSATLEAEQPRVSGLVLFRQLRPGALLEAFHLEGFPNSRAIHVHQFGDLSQGCDSTGPHYNPMSVLHPQHPGDFGNFAVSNLAASLTGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRLACCVVGLCGPGPWAHQAQENAERKKRRRESECKAV >XP_004038545.3 extracellular superoxide dismutase [Cu-Zn] [Gorilla gorilla gorilla] CLLLAAGAAEWIRDMAKVTEIWQEVMQRR--DGALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFALEGFPTSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGNFAVAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRQSECKAA >XP_005501341.1 extracellular superoxide dismutase [Cu-Zn] [Columba livia] --LVA-GLQEPFQDITKVNDLWQSLLYPVAPDRMIYATCEMKPSSKIDADKPQVTGQVLFRQYYSYGRLEAIYLDGFPLGRAIHIHELGDLSNGCDATGGHYNPFRVNHPRHPGDFGNFFPTNLFATMFGPYSIMGRSVVIHEQEDDMGKGNNKASLENGNAGKRLACCVIGICNKNLWEEKLSEVTDKKKRGLNKRTQNQ >XP_006024876.1 extracellular superoxide dismutase [Cu-Zn] [Alligator sinensis] --LVSVGLEGLFQELKKVNDLWQNLLYPQFIDWTAYATCEMKPSSKLDADKPQVTGQILFKQSYPIGKLEAFDLDGFPSGRAIHIHKFGDLSDGCNTTGGHYNPFNVNHPHHPGDFGNFYSSNLSATLFGPYTIMGRSVVIHEQEDDMGKGNNKASLENGNAGRRLACCVIGICDKNMWENKFSKFVERRKRGSQNEHRSR >XP_006260489.1 PREDICTED: extracellular superoxide dismutase [Cu-Zn] [Alligator mississippiensis] --LVSVGLEGLFQELKKVNDLWQNLLYPQFIDWTAYATCEMKPSSKLDADKPQVTGQILFKQSYPIGKLEAFDLDGFPSGRAIHIHKFGDLSDGCNTTGGHYNPFNVNHPHHPGDFGNFYSSNLSATLFGPYTIMGRSVVIHEQEDDMGKGNNKASLENGNAGRRLACCVIGICDKNMWENKFSKFVERKKRGSQNEHRSR >XP_020753289.1 extracellular superoxide dismutase [Cu-Zn] [Odocoileus virginianus texanus] YLLLVACDEEQIRDMTKVTEIWQEVMQRRAADAALHAVCQVQPSATLEAEQPRVSGLVLFRQIRPGTLLEAFHLEGFQDNHAIHVHQFGDLSQGCDSTGPHYNPMSMPHPQHPGDFGNFPVYDLAASLTGPHSIAGRAVVVHAGEDDLGRGGNQASLENGNAGRRLACCVVGLCGPGPWARKAQEHAERRKRRLESECKAG >XP_023109018.1 extracellular superoxide dismutase [Cu-Zn] [Felis catus] YLLLAARAAAQIRDMEKVTAIWQEMTQRQAADAALHAACRVQPSATLDAAQPRVSGLVLFRQQVPGARLEAFDLEGFPASRAIHVHQFGDLSQGCDSTGAHYNPRAVPHPQHPGDFGNFAVGGLAASLFGPHSIVGRAVVVHAGEDDLGRGGNVASVENGNAGPRLACCVVGVCGPLPWARQAQEHAERRKRRRDSECKAV >XP_040191114.1 extracellular superoxide dismutase [Cu-Zn] [Rana temporaria] --LLAVILQSEITTIQKVDEIYDAIYNGVQ-DKAIYATCKLQPSPKLDDDEIKIMGQVLFKQIYPNGELEAVSIEGFPQVRAIHIHDFGDISNGCDSAGGHYNPFSVDHPNHPGDFGNFRVMNLGAKMFGPVSIIGRSIVVHKMADDLGKGDNRASLENGNAGARLACCVIGTTNKNGWEKYMEENAKLKTPRVARRGNMQ
PhyML tree of selected proteins ((((XP_018098563_1_extracellular_superoxide_dismutase__Cu_Zn___Xenopus_laevis_:0.33337537,XP_040191114_1_extracellular_superoxide_dismutase__Cu_Zn___Rana_temporaria_:0.42750059):0.30243948,(((XP_038068816_1_superoxide_dismutase__Cu_Zn__like__Patiria_miniata_:1.03741622,(XP_030829251_1_superoxide_dismutase__Cu_Zn__like_isoform_X2__Strongylocentrotus_purpuratus_:1.52376404,(XP_031572834_1_superoxide_dismutase__Cu_Zn__like_isoform_X2__Actinia_tenebrosa_:0.80046987,(NP_001021956_1_Superoxide_dismutase__Cu_Zn___Caenorhabditis_elegans_:0.4955673,(XP_039262007_1_superoxide_dismutase__Cu_Zn__like__Styela_clava_:0.89394616,(CAE1264788_1_SOD1__Sepia_pharaonis_:0.36553383,(AAD14963_2_slow_superoxide_dismutase__partial__Drosophila_melanogaster_:0.34416644,NP_001171498_1_superoxide_dismutase_1__Apis_mellifera_:0.21628012):0.06986777):0.24015576):0.19347204):0.47400367):0.52845722):0.17323443):0.80593063,(XP_020956182_1_extracellular_superoxide_dismutase__Cu_Zn__isoform_X1__Sus_scrofa_:0.09419693,((((XP_009238123_2_extracellular_superoxide_dismutase__Cu_Zn__isoform_X1__Pongo_abelii_:0.0100276,(XP_004038545_3_extracellular_superoxide_dismutase__Cu_Zn___Gorilla_gorilla_gorilla_:0.0049673,(XP_009445714_1_extracellular_superoxide_dismutase__Cu_Zn___Pan_troglodytes_:0.00000001,(sp_P08294_SODE_HUMAN_Extracellular_superoxide_dismutase__Cu_Zn__OS_Homo_sapiens_OX_9606_GN_SOD3_PE_1_SV_2:0.00000001,XP_008950433_1_extracellular_superoxide_dismutase__Cu_Zn___Pan_paniscus_:0.00000001):0.00000001):0.00000001):0.00000001):0.10336035,(XP_545973_4_extracellular_superoxide_dismutase__Cu_Zn__isoform_X1__Canis_lupus_familiaris_:0.19126724,XP_023109018_1_extracellular_superoxide_dismutase__Cu_Zn___Felis_catus_:0.04132312):0.06899548):0.00661402,(NP_001076101_1_extracellular_superoxide_dismutase__Cu_Zn__precursor__Oryctolagus_cuniculus_:0.06998254,(NP_037012_1_extracellular_superoxide_dismutase__Cu_Zn__precursor__Rattus_norvegicus_:0.08894886,NP_035565_1_extracellular_superoxide_dismutase__Cu_Zn__precursor__Mus_musculus_:0.05210857):0.25739643):0.03669205):0.04478015,((KAB0342939_1_hypothetical_protein_FD754_019865__Muntiacus_muntjak_:0.01797025,(XP_043294215_1_extracellular_superoxide_dismutase__Cu_Zn___Cervus_canadensis_:0.01479292,XP_020753289_1_extracellular_superoxide_dismutase__Cu_Zn___Odocoileus_virginianus_texanus_:0.01976384):0.01139598):0.06726849,(XP_024849041_1_extracellular_superoxide_dismutase__Cu_Zn__isoform_X1__Bos_taurus_:0.02710179,(XP_014951904_2_extracellular_superoxide_dismutase__Cu_Zn__isoform_X2__Ovis_aries_:0.00000001,NP_001272604_1_extracellular_superoxide_dismutase__Cu_Zn__precursor__Capra_hircus_:0.00477359):0.01728205):0.01930284):0.0427985):0.04315371):0.33391694):0.11376142,(tr_E9QIM2_E9QIM2_DANRE_Superoxide_dismutase__Cu_Zn__OS_Danio_rerio_OX_7955_GN_sod3b_PE_3_SV_1:0.59653578,(XP_015799267_1_PREDICTED__extracellular_superoxide_dismutase__Cu_Zn___Nothobranchius_furzeri_:0.13442329,(XP_030247694_1_extracellular_superoxide_dismutase__Cu_Zn___Sparus_aurata_:0.23153318,XP_004084336_2_extracellular_superoxide_dismutase__Cu_Zn___Oryzias_latipes_:0.2067185):0.09403799):0.33392379):0.57337396):0.14394543):0.18121074,(XP_006260489_1_PREDICTED__extracellular_superoxide_dismutase__Cu_Zn___Alligator_mississippiensis_:0.00000001,XP_006024876_1_extracellular_superoxide_dismutase__Cu_Zn___Alligator_sinensis_:0.00487326):0.22798738):0.15918388,XP_005501341_1_extracellular_superoxide_dismutase__Cu_Zn___Columba_livia_:0.07076226,(XP_040525137_1_extracellular_superoxide_dismutase__Cu_Zn___Gallus_gallus_:0.05682118,XP_010708631_2_extracellular_superoxide_dismutase__Cu_Zn__isoform_X1__Meleagris_gallopavo_:0.03547658):0.10057055);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)