PB0015

DATABASE

Click here to access PB0015 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0015	P28300	Protein-lysine 6-oxidase	LOX	AAT10, lysyl oxidase	Homo_sapiens	Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture.

Domains

Gene Ontology

PF01186 (Lysyl_oxidase)

GO:0004720 (enables) protein-lysine 6-oxidase activity GO:0005507 (enables) copper ion binding GO:0005515 (enables) protein binding GO:0005518 (enables) collagen binding GO:0016491 (enables) oxidoreductase activity GO:0016641 (enables) oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0046872 (enables) metal ion binding GO:0001568 (involved in) blood vessel development GO:0001649 (involved in) osteoblast differentiation GO:0001932 (involved in) regulation of protein phosphorylation GO:0006464 (involved in) cellular protein modification process GO:0007507 (involved in) heart development GO:0009410 (involved in) response to xenobiotic stimulus GO:0009725 (involved in) response to hormone GO:0010468 (involved in) regulation of gene expression GO:0016202 (involved in) regulation of striated muscle tissue development GO:0017015 (involved in) regulation of transforming growth factor beta receptor signaling pathway GO:0018057 (involved in) peptidyl-lysine oxidation GO:0018158 (involved in) protein oxidation GO:0030199 (involved in) collagen fibril organization GO:0030282 (involved in) bone mineralization GO:0030324 (involved in) lung development GO:0035791 (involved in) platelet-derived growth factor receptor-beta signaling pathway GO:0035904 (involved in) aorta development GO:0035905 (involved in) ascending aorta development GO:0035906 (involved in) descending aorta development GO:0042060 (involved in) wound healing GO:0042981 (involved in) regulation of apoptotic process GO:0043491 (involved in) protein kinase B signaling GO:0045652 (involved in) regulation of megakaryocyte differentiation GO:0046716 (involved in) muscle cell cellular homeostasis GO:0048251 (involved in) elastic fiber assembly GO:0048514 (involved in) blood vessel morphogenesis GO:0048545 (involved in) response to steroid hormone GO:0055001 (involved in) muscle cell development GO:0060326 (involved in) cell chemotaxis GO:0061448 (involved in) connective tissue development GO:0071310 (involved in) cellular response to organic substance GO:0071897 (involved in) DNA biosynthetic process GO:1900120 (involved in) regulation of receptor binding GO:1903010 (involved in) regulation of bone development GO:1990869 (involved in) cellular response to chemokine GO:2000586 (involved in) regulation of platelet-derived growth factor receptor-beta signaling pathway GO:0005615 (is active in) extracellular space GO:0005576 (located in) extracellular region GO:0005634 (located in) nucleus GO:0031012 (located in) extracellular matrix GO:0005581 (part of) collagen trimer

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P28300|LYOX_HUMAN Protein-lysine 6-oxidase OS=Homo sapiens OX=9606 GN=LOX PE=1 SV=2 MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSL GSQYQPQRRRDPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPT ARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDD NPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAA EENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDE FSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADID CQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY
Selected proteins from model organisms >NP_002308.2 protein-lysine 6-oxidase isoform 1 preproprotein [Homo sapiens] MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRR DPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPTARHWFQAGYSTSRAREAGAS RAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQY GLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPS RPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPG CYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_039262610.1 lysyl oxidase homolog 3A-like isoform X2 [Styela clava] MLVGRLLLFSSSFFFVMSQDLSELQTKAEEKIKIRIRDGPTISEGRVEVLHDGEWGTICDDDWDLNAAQVACRMMGFEGA LDFAHSGKYGPGEGLIQLDNVHCDGEEKSLHECEHRGLGVSDCSHHEDAGVKCSPKKLPDYLTKQWFAASASFDRMRLKP PRGMKKRLPQIFGYVEIFHDEKWRHICTDGWKKENARVICGQLGFPDASDIGHIGKKQKHRNHWLTNLTCTGEETKLVEC DYGLLNYTASESCATGEAALIRCTPGDSYTLSAIKKSIRNQKGGRHHVPQRYTKPHELIRLKSGSTVGEGRLEVMRNGRW GTVCHSYFDIRDATVACRQLGFGTAKRVYPDAYFGMAHGPIWMTNLNCNGNETNLEDCKHDKISEHYTGYGGVNDGCTHT QEVAIACHVPDLNIQRRIRIVGGRNPLEGRVEVQIGKKWGPICSDMWTAKEAMVACRQLGMGYALHALKEVWYYPGSDDA SSLMMTGVECKGDEIGIQYCHHDGKKLRKCGDSKRTMTPFAGVICTEGSPDLITDIPMLSDSIHMEDRGLSNLICAAEEK CLSSSADELDMRTSYGHRRLLRFSSRVWNRGRADFRPARLPNDWEWHSCHGHFHSMAEFTHYDILSLNKTRVAEGHKASF CLEDTHCDDGVSRRYDCDQPGGGTQGITVGCSDTYLYNIDCQWIDITDLPGGNYLFRVHVNPNHLVPESDFSNNEVICNM RYDGQQVWVWNCHIGTDFDPTITANFYTENMFP >NP_001073015.1 lysyl oxidase-like 2 precursor [Strongylocentrotus purpuratus] MQFSVGLFVQYFIFILITCGHGLPSNNETNTNNPTINTESTPIEPTTIAATTTTTSKPTTAKQEETTTQPPKTTQPTTVQ PTTTQPTTTPTTFPPTTGEPTTRPPAKIRARLADGMHPWEGRVEVSMHGGSWGTVCDDGFNMNAANVVCKMVGYKKAVQY FFGSSQFGRGPGRILLDEVECLGTEKNLLACEHNPIGVTDCSHSEDVGIRCIDVVRKVTPPEKKLKQYKFRLVGDPTPKP QSEGVVEVMMTGKWRTICSDGWDMEDARVLCGSLGFKEATSVEPNRKNKSRQRKKSIVASNFECTGNEHNVSDCERTILK SHKDCLSKRAAEAKCERGPFVMDADKPYSPPWSDVRLKAGAAFGEGRLEVFHAGRWGTVCGEDFDKVAASVVCRKLGFGT AETVLENASAFGQGIGPIWLWEVDCKGTEASIMECGHGAYNRSKCDHSQDVGIKCNIPDLGVKEDIRLVQGRFDTEGRVL INYEGQWGHPCGGDSWDMFDAKVACRQLGLGYAHQPMRSTRFMGRSGYPILMLDVNCTGNERTLSECPHVRSDNGTCMAD YKAGILCAGVLPDVLMDVHVLQSSIYMQDWPMYMLQCAAEENCLSSESHVRGARRLLRFASAIMNRGTEEFRPVLGRSSW EWHACHRHYHSMDVFSTYDLLDADGVRVAEGHKASFCLEDVYCDSGAQKVYSCDAGTQGISVNCVDIYRNDIDCQWIDVT GVPQGSYVLRVDVNPNHIVGETDFTNNEVLCDVMLTYRVRIQNCRYADDS >CAE1283062.1 LOXL2_3_4 [Sepia pharaonis] MLPSTTTADIQKTTLAIRHKKAKDVKRNKTSITGASAANRSQPEIKSRDGLNANNNLKDDKKEILKDEGTGTGSNSVGSL PANMDLKDVSGKISARSDHNNNKVSIPSAGSSDIDTRVEEKKIKVNEPEVKEKSETHTDNSSDKEGDKEGQTSEPENQSS VDQSKDHQGKEKFRVTLNGGRYGKEGHVAILLPGEKKWGVVCGDQWTYFEASVVCRQLGLGMVKQVYQINYYGGSHLPKL FARIRCHGNESHLADCERFEYHNQVKCSKDVSVAGVICTNVLPDLIPDALALQKSVRLEDRPLYYLTCSMEENCLADEAY EIKERSHAWITASRRLLRFSSIVYNIGTADFIPNSPKDAWEWHQCHMHYHSMEVFAHYDILDLQGNRIAQGHKASFCLED TRCPPGITPKYNCLGFGDQGLSVNCSDNYYHDIDCQWIDITGIKFGNYILKVEFNPEMYVSEITFDNNVVECSLYYTGTY AYLRKCDIVPLRRRD >XP_016772223.2 lysyl oxidase homolog 4 isoform X3 [Apis mellifera] MDWRILIIGFSIILAIMVDVRTTANSNDTWDEKIREKKARLVKKLKKDLRKLKKQEGAVKLVGGENGGHEGRYWMDNVYC DGSEDELSKCRFDGWGASDCEGGEAAGVICDQQQQEAEDGVRERSKAGRKPEKRRIKDIHQQGVAIRLAGGRVHSEGRVE VKLGHSDWGVICGDGWSLFEAAVVCRQLGLGYASDAVQTNFFGGEKTPMAISGVQCRGNESSLTDCLHDKLLDCPGPVEN VGSVVCLRDMPDLVFDHIELMRTAHLEDRQLYWLQCAMEENCVASQAYKIQKESENWHLETRRLLRFTARILNAGTADFR PSVPKHLWEWHMCHMHYHSMEVFATFDVLDLNGTRLAEGHKASFCLEDNQCLPGVEARYKCANYGDQGISVNCSDIYRHN IDCQWVDISELRPGEYIFKVGVNPELKVGEMSFDNNAAICRLLYTESFATVHSCVMGRP >XP_038065185.1 lysyl oxidase homolog 2A-like isoform X2 [Patiria miniata] MPRDTHFTWWLVRLVVYLSAIALISGGVKGDAPKPAAARLVGGHNPWSGRLEVYFKRQRAYGTVCDDGWHMNASHVACRM MGYAEAMDFHFGNVFGAGKGTIVLDDVRCTGNETHLFKCQHAKLGVSNCRHSEDIGLTCSQDTIQERMEAQRAAERRQMK VRLVGGSKLQPISEGVVELLYKGKWRTVCGEDWDTLDSRVVCGMVGFKDSMPLREGYQEAGNFQRRKSMRITNVQCTGSE VHIGTCPFDDLANEEDCPSDIVAHARCHRGDFVLDTPYDENGMPVEGTAAEDNEEIVQNEEITSAGAEGNTSADAEVNDA GMNNNTSSTTMPETTTDIDAQEILNDDAGQAKRRKGKSKAARKQATPEVLVIKKPKPTIRLKSGAYYGEGRVEVYVNGLW GTICSEGWDEVSASVACRQLGFGVAEKAVRNSEFGQGVGPIWLWRMRCEGHEKTLLDCDHGYLNGSRCTHAQDASVQCVV PDIDAASKVRIEGGTYEREGRVAVYINGEWGNICGWNWGLLAGKVVCRQLGLGHARYAPESTLSYGSAPKRTFLMMEVKC TGHERTIKECKYTRPSNANTCIRAFRAGVVCVDTLPDVLMDLHVLQSSVRVQDWPDTLLTCAREEGCLSDVPNNWGLRRL LRFTSAIMNRGMEQFRPLLSRYSWKWHLCHRHFHSMEVFSHYDLINQKGERVAQGHKASFCLEDGHCDEGITPQFSCITD QGISVNCIDIYASNIDCQWVDVTGVKTDLYTLRIHINPDNLVAESDYDNNLIECDLYYGRRITIGHCEYVTDRMNG >CAB99481.1 lysyl oxidase-like 2 [Drosophila melanogaster] MCAIEDRKVLKMGLTLVCLTLLAIHMADAVVQHRSLEDARQERQRLVHRYTKVLNKEEGAIRLVGGDNEYEGNIEVLHNG KWGAVCDDEWDSTEADIVCRQLGFPGMRRYTRSGFFGPARRRFWMDNLFCEGHEQELVDCHFEGWGENDCEPGEAAGVVC YPPENALIPMATPIIRDEDLPKYPIHSRSRLYVRLRGGRSRIEGRVEVSLDGGRWGSVCADGWSLLEANVVCRQLGLGYA SEAFQTDFFGGFNVSRPVLSGSECYGNETELADCLHHDASQGIISCHGNRQHVAAVICDYIAPDLVVDYLEIEQTAHLED RPMLLMQCAMEENCVANEAYQIQRDDPHWRYRSRRLLKFTAAAINAGNADFRPFKEKSQWEWHMCHMHFHSMEVFATFDI FNLRGIKVAQGHKASFCLEDSNCLPGVAKKYNCANSGDQGISINCSDVYLYNLDCQWVDVTDLIPGTYVLKIAINPEFKV AEMNYDNNAAICDLIYTANFARVQNCQLGRP >XP_031556434.1 lysyl oxidase homolog 2A-like [Actinia tenebrosa] MFPVRAVLFSILSLFICSSVARRLQIRMVQGKHHYEGRIEVLHNDKWGEVCDHKWDLKGAKVACRMLGFPDALRYTSGDW FGRGSGYFWMDDVQCNGDEWTLERCSRKDWGRCNCRRGQTAGVVCRMRDEEYVIKPSPSNASKEIVDLPIRLLGPMLHDL ISEGLVQVQIDKQWGYVCSHGWTEMNSRVACGMLGYKDYHRGPLVRPQKTSEKKEKDLPEGAFMVSNVSCAGHESSFVEC RHKGWGPLKCEGGFPVRIKCSRSPMFVNPNLRLRGSFNLHEGRVEVRNPNPSSKQHWGTVCDDHFGLKDANVVCRSIGLG TASRVFTNAHFGQGVRGIYKDDVNCNGWERDFGDCRANLQSNCNHYEDVSVRCNVPKLYNNKIRIAGGMTPHEGRVEVFD GKRWGAVCAEHWGIEEAVVACRHLGLGFAKNAITSNYFGVTSLPVIFSNVDCKLDEISLHHCERAIPKITRCRSGRKAGI ICTRAVPDLVVNVDELEKNVRIDAIPLAYMQCSYEENCLGESAREQWPNNRYYTRRLLRFTTRVENRGLAPFKPDVPKSS WQWHQCHNHYHSMEVFSTYDLVDFSGIKAAAGHKASFCLEDTVCDEGIPKTFNCTDGGDQGISPNCYDVYKWNIDCQWID VTDFPHGSFYLRVTVNPDRKVAESDYLNNIAKCELYDYGNFAVAAKCHLEECQSGMDTHGGNAKGACCVFPFKYRNKVYR SCTKSGYNRFWCSTTSDFDRSRRWGICY >KAB0387850.1 hypothetical protein FD755_002806 [Muntiacus reevesi] MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRDSGATAPGAAN ATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAAAAAGRPRPAARHWFQAGYSTSGAQDAGTSRADNQTAPGEVPTLSNL RPPNRVDVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYN LRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRV AEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNV VRCEIRYTGHHAYASGCTISPLSELHGNLSGCAHFANY >KAB0358923.1 hypothetical protein FD754_003079 [Muntiacus muntjak] MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRDSGATAPGAAN ATAPQMRTPILLLRNNRTAAARVRAAGPSAAAAAAGRPRPAARHWFQAGYSTSGAQDAGTSRADNQTAPGEVPTLSNLRP PNRVDVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLR CAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAE GHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVR CEIRYTGHHAYASGCTISPLSELHGNLSGCAHFANY >XP_043321819.1 protein-lysine 6-oxidase isoform X1 [Cervus canadensis] MRFAWTALLGSLQLCALVRCAPPAAGHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRDPGAAAPGAAN ATAPQMRTPILLLRNNRTAAARARTAGPFAAAAAAGRPRPAARHWFQAGYSTSGAQDAGTSRADNQTAPGEVPTLSNLRP PNRVDVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLR CAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAE GHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVR CEIRYTGHHAYASGCTISPY >NP_001089167.1 lysyl oxidase L homeolog precursor [Xenopus laevis] MGCAPGRVFLLQLVLYLHCLLLGDCQQQRSPVGPSSMWRQRLQWQSNGRVYSLLSHGSEYQPARRREQEGSAPHSPLLLL SSRHNNSVSQGTGAHRAQPPRSVTPSAEGQQQQPASTNPAAREDAAATSRLWFQATRQRNAGDAAGRQRSAGAAQERRQG AQASHTRVNGTDRVEGMQGDDPYNPYKYSEDNPYYNYYDTYERSRTNERQRPGYGTRYFQNGLPDLVPDPYYIQASIYVQ KMSMYNLRCAAEENCLASSAYSSDVRDYDQRVLLRFPQRVKNQGTADFLPSRPRYTWEWHSCHQHYHSMDEFSHYDLLDA SSHRRVAEGHKASFCLEDTSCDYGYYRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYQVPES DYSNNVVRCDLRYTGHYVYTSGCTISPY >NP_996972.1 protein-lysine 6-oxidase precursor [Danio rerio] MSMSLIDTFIYAFAHVCLLSCIAQTGQTQRQGNTGAAALRQTIQWQHNGKLFSILSQGSEYQPPLKRDGNKEQAQARPVA IVRNDDAATRTDSSAPSRASQSRGSVRVPSGTGARGGASRWLSGDGARTRGVHGRRNHTDPLRSINGTDRPAGDDEVMVG DDPYNPYKSTDPDNPYYNYYDTYERPRPAQRPGYGTGYFQNGLPDLVGDPYYIQASTYVQRVPMYNLRCAAEENCLASSA YRSSVRDYDMRMLLRFPQRVKNQGTSDFLPSRPRYTWEWHSCHQHYHSMDEFSHYDLLDATTHRRVAEGHKASFCLEDTS CDYGYYRRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYQVPESDYSNNVVRCDVRYTGNYAYV SGCHISQY >XP_004074853.1 protein-lysine 6-oxidase [Oryzias latipes] MWLRQFGASRYAYARICLFVLSLHTVHSQRNPGSQQRNEQSAALRQTLQWSHNGKVFSILSQGAEYQPARRRGAPQEQVR AQQITIVQDADERRQDTQQQSVARQDQQPPRSVPPQLQRLVRGPEHRQQLQHERFGERVNDTQKVNVSSSLPRREDMMVG DDPYDPYKSIDGDNPYYNHYDVYERPRERQRPGYGTRYHQYGLPDLVPDPYYIQASAYVQRSPMYNLRCAAEENCLSSSA YRSSIRDYDTRVLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHFHSMDEFSHYDLLDATSQRSVAEGHKASFCLEDTS CDYGYYRRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPYYQVPEQDYSNNIVRCDVRYTGNYAYV SGCHMSTY >XP_015796584.1 PREDICTED: protein-lysine 6-oxidase-like [Nothobranchius furzeri] MELRAFCASRYLRICLFVFLLQVSRCQRNPAARQRHEEGAALRQTLQWSHNGQVFSILSHGSEYEPPKRRSAPQQQVQPR PVTIIRDAEAVRPQDARSQQQQQPPRSSIPQPLQRLVRGREHRQHLHRERPGARAGTQESPRVNDAQGKVNVSRPTEDVM LGDDPYDPYKSIDSDNPYYNYYDAYEQPRPRSRPGYGTRYHQYGLPDLVPDPYYIQSSVYVQRVPMYSLRCAAEENCLSS SAYRSRDYDNRMLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHYHSMDEFSHYELLDATTHRAVAEGHKASFCLEDTS CDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGEYTLKISVNPYYQVPESDYSNNIVRCDVRYTGNYAHV SGCHMSTY >XP_030290565.1 protein-lysine 6-oxidase-like [Sparus aurata] MGLRIFGTPLYAYACVYFFVFILQVAQSQRSPGTQQGEQQRAALRQTLQWSHNGKIFSILSQGSEYQPPRRRGAPQEQVQ ARPVTIIRDANVRPQDTSSQQQQPPRPTSGAHSPGGLPPPLQRLVRGREHRQHPRERPGERAEPQRSSRANDTQDKVTVS PPLPRRQDMMVGDDPYNDPYKSMDGDNPYYNYYDVYERPRPRPRPGYGTRDHQYGLPDLVPDAYYIQAAAYVQRVPMYNL RCAAEENCLSSSAYRSSVRDYDTRMLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHFHSMDEFSHYELLDANTHHQMA EGHKASFCLEDTSCDYGYYRRFACTAHTQGLSPGCFDTYNADIDCQWIDITDVKPGSYILKVSVNPQYQVPESDYSNNIV RCDVRYDGNYAHVSGCHMSSY >KAF4017962.1 hypothetical protein G4228_009537 [Cervus hanglu yarkandensis] MALALTGWQLVWGACVCVLVHGQQAPPGQGSDPGRWRQLIQWENNGQVYSLLNSGAEYVPPGPQGSEANSRVLLAGAPQA PPRRSQGGLRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDNTGMARARTSVSQQRHGGSASSVSASAF ASTYRQPSSFPQQQFPYPQAPFVSQYETYDPATRTYDQGYVYYRSAGGGLGAAAVASAGVVYPFQPRARYEEYGGGGGEE QPEYPPQGFYPAAPERPYAPQPADGLDRRYSHSLYHEGTAGLEPAYPDPGPDAAQPNGGGGGGTYGGGGGDHRLGWYPPY GNMPPEAYSPPRAVEPQPPFRVLEPPYLPVRSSDAPPPGSERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTY VQRAHLYSLRCAAEEKCLASTAYGPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLL DAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVL ESDFTNNVVRCNIHYTGRYVSTTNCKIVQ >OWK10657.1 LOXL3 [Cervus elaphus hippelaphus] MRPVGVWRWSLWGLLLRLLCSPCLGSPTPSGAPEKRAGSQGLRFRLAGFPRKPFEGRVEIQRAGEWGTICDDDFTLQAAH VLCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTERSVTECASRGWGNSDCTHDEDAGVICKDERLPGFSDSNVIEV EHHLQVEEVRLRPAVGRGRRPLPVTEGLVEVRLPDGWSQVCDKGWTAHNSHVICGMLGFPSEKRVNVAFYRKLRKRAAKA SARRSKPLGRPVTKLKAKPKTRMGRGPVKRLLARRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTTRCPGGAPAVVSC VPSPLYAASSGQKKQQSKPQGEARVRLKGGAHPGEGRVEVLKAGTWGTVCDRKWDLQAASVVCRELGFGSAREALSGARM GQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGVETKVSHSFHLGSDDWGTLEAMVACRQLGL GYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHVTCKRTGSRFTAGVICSETASDLLLHSALVQETAYI EDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTP NGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAES DFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQVI >NP_034858.2 protein-lysine 6-oxidase preproprotein [Mus musculus] MRFAWAVLLLGPLQLCPLLRCAPQTPREPPAAPGAWRQTIQWENNGQVFSLLSLGAQYQPQRRRDPSATA RRPDGDAASQPRTPILLLRDNRTASTRARTPSPSGVAAGRPRPAARHWFQAGFSPSGARDGASRRAANRT ASPQPPQLSNLRPPSHIDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGSRNRPGYGTGYFQYGLPDLV PDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSW EWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYA ADIDCQWIDITDVQPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >NP_058757.1 protein-lysine 6-oxidase precursor [Rattus norvegicus] MRFAWTVLFLGQLQFCPLLRCAPQAPREPPAAPGAWRQTIQWENNGQVFSLLSLGAQYQPQRRRDSSATA PRADGNAAAQPRTPILLLRDNRTASARARTPSPSGVAAGRPRPAARHWFQVGFSPSGAGDGASRRAANRT ASPQPPQLSNLRPPSHVDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRSGSRHRPGYGTGYFQYGLPDLV PDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSW EWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYA ADIDCQWIDITDVQPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >NP_776357.2 protein-lysine 6-oxidase precursor [Bos taurus] MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRD PGATAPGAANATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAGRPRPAARHWFQAGYSTSGAHDAGTSR ADNQTAPGEVPTLSNLRPPNRVDVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQ YGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRGDVRDYDHRVLLRFPQRVKNQGTSDFLP SRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSP GCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >NP_990812.2 protein-lysine 6-oxidase precursor [Gallus gallus] MRCAPPGLLLAQLHACIFWSGLWPAGCQSPPAAWRQRIQWENNGQVYSLLSQGAQYQPPRRRQGAEPASS PVLLLRGNGSVPRAAAAAAARPQPEPQPQAQPQPRPRSSRRQPLGRRHWFQAGYRAPSGSARPAPRRRPR GRRSRRRERAERRRAAAPSGLRPGREDVMVGDDPYSPYKYTDDNPYYNYYDTYERPRQGSRYRPGYGTGY FQYGLPDLVPDPYYIQASTYVQRMSMYNLRCAAEENCLASSAYRADVRDYDNRVLLRFPQRVKNQGTSDF LPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGL SPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDIRYTGHHAYASGCTISP >XP_001153015.1 protein-lysine 6-oxidase [Pan troglodytes] MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRR DPGAAVPGAANASAQQPRTPILLIRDNRTAAARARTAGSSGVTAGRPRPTARHWFQAGYSTTRAREAGAS RAENQTAPGDVPALSNLQPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQY GLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPS RPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPG CYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_005626496.1 protein-lysine 6-oxidase isoform X1 [Canis lupus familiaris] MRFAWTALLLGPLQLCALLRCAPPAAGQQQPPRQPPAAPAAWRQRIQWENNGQVFSLLSLGSQYQPQRRR DPGTTAPGAANAAAPQPRTPILLLRNRTAAARERAAGTAGGAGRPRPAARHWFQAGYSASGARDANQTAP GERPALSNLRPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPD PYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEW HSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_008253171.1 PREDICTED: protein-lysine 6-oxidase isoform X1 [Oryctolagus cuniculus] MLCSWTVLLLGPLQLCALVCGAPQAAGQQQPPREPPAAPGAWRQRIQWENNGQVFSLLSLGAQYQPQRRR DAGAAAPGAQRAAGPQQRTPVLLLRDNRTAAASRPRPAGRHWFQAGYASPGARDAGASRAGNRTAQGEPP ALSNLRPPSHVDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPDPYYI QASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCH QHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYAADIDCQ WIDITDVQPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_009239271.1 protein-lysine 6-oxidase [Pongo abelii] MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPQREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRR DPGAAVPGAANASAQQPRTPILLIRDNRTAAARARTAGSSGVTAGRPRPTARHWFQAGYSTSTAREAGAS RAENQTALGDVPALSNLQPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQY GLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPS RPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPG CYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >NP_001193332.1 protein-lysine 6-oxidase precursor [Sus scrofa] MRFAWTSLLLGLLQLCAPVRCAPPATGQQQPPREPPAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRR DPGATAPGAANATTPQLRTPILLLRNNRTAAARARTALSSGAVAGRPRPAARHWFQAGYSTSGARDAGAS SAGNQTAPGELPALSNLQPPSRVDVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGSRYRPGYGTGYF QYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFL PSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLS PGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_003826749.1 protein-lysine 6-oxidase [Pan paniscus] MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRR DPGAAVPGAANASAQQPRTPILLIRDNRTAAARARTAGSSGVTAGRPRPTARHWFQAGYSTTRAREAGAS RAENQTAPGDVPALSNLQPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQY GLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPS RPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPG CYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_023110382.1 protein-lysine 6-oxidase isoform X1 [Felis catus] MRFAWTALVLGPLQLCALLRCAQPAAGQQQPPRQPPAAPAAWRQRIQWENNGQVFSLLSLGSQYQPQRRR DPGATAPGAANAAVPQPRTPILLLRNRTAAARERTPGSSGATGRPRPAARHWFQAGYSPSGARDAGDSRD GNGTEPGERPALSNLRPPSRVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGL PDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRP RYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCY DTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_027825796.1 protein-lysine 6-oxidase isoform X1 [Ovis aries] MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRD PGATAPGAANATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAGRPRPVARHWFQAGYSTSGAHEAGTSR ADNQTAPGEVPTLSNLRPPNRVDVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQ YGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLP SRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSP GCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_004042452.3 protein-lysine 6-oxidase [Gorilla gorilla gorilla] MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRR DPGAAVPGAANASAQQPRTPILLIRDNRTAAARARTAGSSGVTAGRPRPTARHWFQAGYSTSRAREAGAS RAENQTAPGDVPALSNLQPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQY GLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPS RPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPG CYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_005506283.1 protein-lysine 6-oxidase isoform X1 [Columba livia] MSMYNLRCAAEENCLASSAYRADVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDE FSHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVK PGNYILKVSVNPSYLVPESDYSNNIVRCDIRYTGHHAYASGCTISPY >XP_005682773.2 PREDICTED: protein-lysine 6-oxidase isoform X1 [Capra hircus] MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRD PGATAPGAANATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAGRPRPVARHWFQAGYSTSGANEAGTSR ADNQTAPGEVPTLSNLRPPNRVDVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQ YGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLP SRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSP GCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_025066263.1 protein-lysine 6-oxidase isoform X1 [Alligator sinensis] MSMYNLRCAAEENCLASSAYRSDVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDE FSHYDLLDANSYRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVK PGNYILKVSVNPSYLVPESDYSNNVVRCDIRYTGHHAYASGCTISPY >XP_019333711.1 PREDICTED: LOW QUALITY PROTEIN: protein-lysine 6-oxidase [Alligator mississippiensis] MRPAPAAAVALLAQLHVCLYLGCAGQPRRAPPPPAAWRQRIQWENNGQVFSLLSLGARYQPARRGAAPAA AASPVLLLRNNRTAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPAPTPARAPSAPRPGREDIM VGDDPYNPYKYTDDNPYYNYYDTYERPRQGSSYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQRMSMYNL RCAAEENCLASSAYRSDVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDL LDANSYRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYIL KVSVNPSYLVPESDYSNNVVRCDIRYTGHHAYASGCTISP >XP_019466272.1 protein-lysine 6-oxidase [Meleagris gallopavo] MDEFSHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDIT DVKPGNYILKVRS >XP_020754628.1 protein-lysine 6-oxidase isoform X1 [Odocoileus virginianus texanus] MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRD PSATAPGAANATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAAAGRPRPAARHWFQAGYSTSGAQDAGT SRADNQTAPGEVPTLSNLRPPNRVDVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGY FQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDF LPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGL SPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_040200086.1 protein-lysine 6-oxidase isoform X1 [Rana temporaria] MGCTKGSVFLLQLAVYFYCILQGSCQSYRSQSSHSAFWKHRVQWQNSGRVYNLLSQGSEYKPPRRRESVE STPSRSILLLSAKNHTSISLSEPGRPQSSNPGNNQTPGLERSNPQRLRDSSGQLSVQASRARSRAGDATG QQRTREDAIRARHQSTPRPSNRQQPQTVNATAVNSIRQDVAQGLQGDDPYNPYKYSEDNRYQNQFDTYER RRESLRRRPGNGMQYIQHGLPDLVPDPYYIQSSIYVQKMSMYSLRCAAEENCLASSAYRSDVRDYDQRVL LRFPQRVKNQGTADFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASSQRRVAEGHKASFCLEDTSCDY GYYRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDVRY TGQHVYTSSCTISPY
Mafft alignment of selected proteins >NP_002308.2 protein-lysine 6-oxidase isoform 1 preproprotein [Homo sapiens] M---------RFAWTV---LLLG-----------------------PLQLCALVH----- ----------------------------------------CAPPAAGQQQP-PREPPA-- ------------APGAW----------------------RQQIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA AVPGA------------------ANASAQQPRTPI-----LLIRDN-----R-------T AAARTRTAGSS--------------------------GV--------TAGR--------- ------------------------------------------------------------ --------------PRPTA-----------------------------RHWFQAGYSTSR ARE---------------------AGASRA-E----------------NQTAPGEVPALS --NLRP--PSR-------------VDGMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GGRYRPGY-GTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYGAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_039262610.1 lysyl oxidase homolog 3A-like isoform X2 [Styela clava] M----------LVGRL---LLFS-------------------------SSFFFVM----- ------------------------------------SQDLSELQTKAEEKIKIRIRDGP- TISEGRVEVL--HDGEWGTICDDDWDLNAAQVACRMMGFEGALDFAHSG-KYGPGEGLIQ LDNVHCDGEEKSLHECEHRGLGVSDCSHHEDAGVKCSPKKLPDYLTKQWFAAS--ASFDR MRLKPPRG-MKKRLPQIFGYVEIFHDEKWRHICTDGWKKENARVICGQLGFPDASDIG-- -----------------------------------------HIGKKQKHRNH---WLTNL TCTGEETKLVECDYGLLNYTASESCATGEAALIRCTPGDSYTLSAIKKS----------- ----------------------------------------------------------IR NQKGGRHHVPQRYT-------KPHELIRLKSGSTVGEGRLEVMRNG-----RWGTVCHSY FDIRDATVACRQLGFGTAKRVYPDAY---------FGMA--------HGPIWMTNLNCNG NETNLEDCKHDKISEHYTGYGGVNDGCTHTQEVAIAC----------------------- ------------HVPDLNI---QR----------------------RIRIVGGRNPLEGR VEVQI-----------------GKKWGPIC-SDM---W---------TAKEAMVACRQLG -MGYALH-ALK-------------EVWYYPGSDDAS-SLMMTG-VECKGDEIGIQYCHHD GKKLRKCGDSKRTMTPF-AGVICTEGSPDLITDIPMLSDSIHMEDRGLSNLICAAEEKCL SSSADELDMRT---SYGHRRLLRFSSRVWNRGRADFRPARLPNDWEWHSCHGHFHSMAEF THYDILSLNKT-RVAEGHKASFCLEDTHCDDGVSRRYDCDQPGGGTQGITVGCSDTYLYN IDCQWIDITDLPGGNYLFRVHVNPNHLVPESDFSNNEVICNMRYDGQQVWVWNCHIGTDF DPTIT--------------------------ANFY-----TENMFP--------- >NP_001073015.1 lysyl oxidase-like 2 precursor [Strongylocentrotus purpuratus] MQFSVGLFVQYFIFIL---ITCGHGLPSNNETNTNNPTINTESTPIEPTTIAATTTTTSK PTTAKQEETTTQPPKTTQPTTVQPTTTQPTTTPTTFPPTTGEPTTRPPAKIRARLADGM- HPWEGRVEVSM-HGGSWGTVCDDGFNMNAANVVCKMVGYKKAVQYFFGSSQFGRGPGRIL LDEVECLGTEKNLLACEHNPIGVTDCSHSEDVGIRCI------DVVRKVTPPE--KKLKQ YKFRLV-G-DPTPKPQSEGVVEVMMTGKWRTICSDGWDMEDARVLCGSLGFKEATSV--- -------------------------------------EPNRKNKSRQRKKSI---VASNF ECTGNEHNVSDCERTILKSHKD--CLSKRAAEAKCERGPFVMD---ADK----------- ----------------------------------------------------------PY SPPWS--------------------DVRLKAGAAFGEGRLEVFHAG-----RWGTVCGED FDKVAASVVCRKLGFGTAETVLENASA--------FGQG--------IGPIWLWEVDCKG TEASIMECGHGAYNR---------SKCDHSQDVGIKC----------------------- ------------NIPDLGV---KE----------------------DIRLVQGRFDTEGR VLINY-----------------EGQWGHPCGGDS---W---------DMFDAKVACRQLG -LGYAHQ-PMR-------------STRFM-GRSGY--PILMLD-VNCTGNERTLSECPH- ----VRSD-NGTCMADYKAGILCAGVLPDVLMDVHVLQSSIYMQDWPMYMLQCAAEENCL SSESH---------VRGARRLLRFASAIMNRGTEEFRPVLGRSSWEWHACHRHYHSMDVF STYDLLDADGV-RVAEGHKASFCLEDVYCDSGAQKVYSC---DAGTQGISVNCVDIYRND IDCQWIDVTGVPQGSYVLRVDVNPNHIVGETDFTNNEVLCDVMLT-YRVRIQNCRYADDS ------------------------------------------------------- >CAE1283062.1 LOXL2_3_4 [Sepia pharaonis] M-----------------------------------------------LPSTTTA----- ------------------------------------------------------------ ------------------------------------------------------------ --DIQKTTLAIR------------------------------------------------ ------------------------------------------------------------ --------------------------------------HKKAKDVKRNKTSI-------- -------------------------------------------TGASAA----------- ----------------------------------------------------------NR SQPEI------------------KSRDGLNANNNLKDDKKEILKDE-----GTGTGSNSV GSLPANMDLKDVSGKISARSDHNNNKVSI----PSAGSSD------IDTRVEEKKIKVNE PEVKEKSETHTDNSSDKEGDKEGQTSEPENQSSVDQS----------------------- ------------KDHQGKE---KF----------------------RVTLNGGRYGKEGH VAILLP---------------GEKKWGVVC-GDQ---W---------TYFEASVVCRQLG -LGMVKQ-VYQ-------------INYY--GGSHL--PKLFAR-IRCHGNESHLADCERF ----EYHNQVKCSKDVSVAGVICTNVLPDLIPDALALQKSVRLEDRPLYYLTCSMEENCL ADEAYEIKERSHAWITASRRLLRFSSIVYNIGTADFIPNSPKDAWEWHQCHMHYHSMEVF AHYDILDLQGN-RIAQGHKASFCLEDTRCPPGITPKYNCL--GFGDQGLSVNCSDNYYHD IDCQWIDITGIKFGNYILKVEFNPEMYVSEITFDNNVVECSLYYTGTYAYLRKCDIVPL- -------------------------------RRRD-------------------- >XP_016772223.2 lysyl oxidase homolog 4 isoform X3 [Apis mellifera] M-----------DWRI---LIIG-----------------------FSIILAIMV----- ------------------------------------------------------------ ------------------------------------------------------------ --DVRTTANSND------------------------------------------------ -----------------------------------TWD---------------------- ------------------------------------------EKIREKKARL-------- -------------------------------------------VKKLKKDL--------- ---------------------------------------------------------RKL KKQEG--------------------AVKLVGGEN-------------------------- ------------------------------------GGH--------EGRYWMDNVYCDG SEDELSKCRFDGWGA---------SDCEGGEAAGVICD---------------------- ---------QQQQEAEDGV---RERSKAGRKPEKRRIKDIHQQG-VAIRLAGGRVHSEGR VEVKL----------------GHSDWGVIC-GDG---W---------SLFEAAVVCRQLG -LGYASD-AVQ-------------TNFF--GGEKT--PMAISG-VQCRGNESSLTDCLH- ----DKLLDCPGPVENV-GSVVCLRDMPDLVFDHIELMRTAHLEDRQLYWLQCAMEENCV ASQAYKIQKESENWHLETRRLLRFTARILNAGTADFRPSVPKHLWEWHMCHMHYHSMEVF ATFDVLDLNGT-RLAEGHKASFCLEDNQCLPGVEARYKCA--NYGDQGISVNCSDIYRHN IDCQWVDISELRPGEYIFKVGVNPELKVGEMSFDNNAAICRLLYTESFATVHSCVMGRP- ------------------------------------------------------- >XP_038065185.1 lysyl oxidase homolog 2A-like isoform X2 [Patiria miniata] M-----PRDTHFTWWLVRLVVYL-------------------------SAIALIS----- ----------------------------------------GGVKGDAPKPAAARLVGGH- NPWSGRLEVYFKRQRAYGTVCDDGWHMNASHVACRMMGYAEAMDFHFGN-VFGAGKGTIV LDDVRCTGNETHLFKCQHAKLGVSNCRHSEDIGLTCS-----QDTIQERMEAQRAAERRQ MKVRLV-G-GSKLQPISEGVVELLYKGKWRTVCGEDWDTLDSRVVCGMVGFKDSMPL--- ------------------------------------REGYQEAGNFQRRKSM---RITNV QCTGSEVHIGTCPFDDLANEED--CPSDIVAHARCHRGDFVLDTPYDENGMPVEGTAAED NEEIVQNEEITSAGAEGNTSADAEVNDAGMNNNTSSTTMPETTTDIDAQEILNDDAGQAK RRKGKSKAARKQATPEVLVIKKPKPTIRLKSGAYYGEGRVEVYVNG-----LWGTICSEG WDEVSASVACRQLGFGVAEKAVRNSE---------FGQG--------VGPIWLWRMRCEG HEKTLLDCDHGYLNG---------SRCTHAQDASVQC----------------------- ------------VVPDIDA---AS----------------------KVRIEGGTYEREGR VAVYI-----------------NGEWGNIC-GWN---W---------GLLAGKVVCRQLG -LGHARY-APE-------------STLSY-GSAPKR-TFLMME-VKCTGHERTIKECKY- ----TRPSNANTCIRAFRAGVVCVDTLPDVLMDLHVLQSSVRVQDWPDTLLTCAREEGCL SDVPN---------NWGLRRLLRFTSAIMNRGMEQFRPLLSRYSWKWHLCHRHFHSMEVF SHYDLINQKGE-RVAQGHKASFCLEDGHCDEGITPQFSCI----TDQGISVNCIDIYASN IDCQWVDVTGVKTDLYTLRIHINPDNLVAESDYDNNLIECDLYY-GRRITIGHCEYVTD- -------------------------------RMNG-------------------- >CAB99481.1 lysyl oxidase-like 2 [Drosophila melanogaster] M-------CAIEDRKV---LKMG-----------------------LTLVCLTLL----- ------------------------------------------------------------ ------------------------------------------------------------ --AIHMADAVVQ------------------------------------------------ ------------------------------------------------------------ --------------------------------------HRSLEDARQERQRL-------- -------------------------------------------VHRYTK----------- ----------------------------------------------------------VL NKEEG--------------------AIRLVGGDNEYEGNIEVLHNG-----KWGAVCDDE WDSTEADIVCRQLGFPGMRRYTRSGF---------FGPA--------RRRFWMDNLFCEG HEQELVDCHFEGWGE---------NDCEPGEAAGVVC----------------------- ------------YPPENAL---IPMATPIIRDEDLPKYPIHSRSRLYVRLRGGRSRIEGR VEVSL----------------DGGRWGSVC-ADG---W---------SLLEANVVCRQLG -LGYASE-AFQ-------------TDFF--GGFNVS-RPVLSG-SECYGNETELADCLHH DAS-QGIISCHGNRQHV-AAVICDYIAPDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCV ANEAYQIQRDDPHWRYRSRRLLKFTAAAINAGNADFRPFKEKSQWEWHMCHMHFHSMEVF ATFDIFNLRGI-KVAQGHKASFCLEDSNCLPGVAKKYNCA--NSGDQGISINCSDVYLYN LDCQWVDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIYTANFARVQNCQLGRP- ------------------------------------------------------- >XP_031556434.1 lysyl oxidase homolog 2A-like [Actinia tenebrosa] M----------FPVRA---VLFS-------------------------ILSLFIC----- --------------------------------------------SSVARRLQIRMVQGK- HHYEGRIEVL--HNDKWGEVCDHKWDLKGAKVACRMLGFPDALRYTSGD-WFGRGSGYFW MDDVQCNGDEWTLERCSRKDWGRCNCRRGQTAGVVCRMR--DEEYVIKPSPSNASKEIVD LPIRLL-G-PMLHDLISEGLVQVQIDKQWGYVCSHGWTEMNSRVACGMLGYKDYHRGP-- -----------------------------------LVRPQKTSEKKEKDLPEGAFMVSNV SCAGHESSFVECRH---KGWGPLKCEGGFPVRIKCSRSPMFV------------------ ------------------------------------------------------------ -----------------------NPNLRLRGSFNLHEGRVEVRNPNPSSKQHWGTVCDDH FGLKDANVVCRSIGLGTASRVFTNAH---------FGQG--------VRGIYKDDVNCNG WERDFGDCRAN-----------LQSNCNHYEDVSVRC----------------------- ------------NVPKL-Y---NN----------------------KIRIAGGMTPHEGR VEVFD-----------------GKRWGAVC-AEH---W---------GIEEAVVACRHLG -LGFAKN-AIT-------------SNYF--GVTSL--PVIFSN-VDCKLDEISLHHCER- ----AIPK-ITRCRSGRKAGIICTRAVPDLVVNVDELEKNVRIDAIPLAYMQCSYEENCL GESAREQWPNN---RYYTRRLLRFTTRVENRGLAPFKPDVPKSSWQWHQCHNHYHSMEVF STYDLVDFSGI-KAAAGHKASFCLEDTVCDEGIPKTFNCT--DGGDQGISPNCYDVYKWN IDCQWIDVTDFPHGSFYLRVTVNPDRKVAESDYLNNIAKCELYDYGNFAVAAKCHLEECQ SGMDTHGGNAKGACCVFPFKYRNKVYRSCTKSGYNRFWCSTTSDFDRSRRWGICY >KAB0387850.1 hypothetical protein FD755_002806 [Muntiacus reevesi] M---------RFAWTA----LLG-----------------------SLQLCALVR----- ----------------------------------------CAPPAASHRQP-PREQAA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDS--------- ------------------------------------------------------------ ----------------------------------------------------------GA TAPGA------------------ANATAPQMRTPI-----LLLRNN-----R-------T AAARVRTAGPSA----------------------AAAAA--------AAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSTSG AQD---------------------AGTSRA-D----------------NQTAPGEVPTLS --NLRP--PNRVD-----------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPLS ELHGNLSG-----C-----------------AHFANY------------------ >KAB0358923.1 hypothetical protein FD754_003079 [Muntiacus muntjak] M---------RFAWTA----LLG-----------------------SLQLCALVR----- ----------------------------------------CAPPAASHRQP-PREQAA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDS--------- ------------------------------------------------------------ ----------------------------------------------------------GA TAPGA------------------ANATAPQMRTPI-----LLLRNN-----R-------T AAARVRAAGPS------------------------AAAA--------AAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSTSG AQD---------------------AGTSRA-D----------------NQTAPGEVPTLS --NLRP--PNRVD-----------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPLS ELHGNLSG-----C-----------------AHFANY------------------ >XP_043321819.1 protein-lysine 6-oxidase isoform X1 [Cervus canadensis] M---------RFAWTA----LLG-----------------------SLQLCALVR----- ----------------------------------------CAPPAAGHRQP-PREQAA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA AAPGA------------------ANATAPQMRTPI-----LLLRNN-----R-------T AAARARTAGPF------------------------AAAA--------AAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSTSG AQD---------------------AGTSRA-D----------------NQTAPGEVPTLS --NLRP--PNRVD-----------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >NP_001089167.1 lysyl oxidase L homeolog precursor [Xenopus laevis] M---------GCAPGR---VFL-------------------------LQLVLYLH----- ----------------------------------------CLLLGDCQQQ---RSPVG-- ------------PSSMW----------------------RQRLQWQSNGRVY-------- --SLLSHGSEYQ------------------------------------------------ ----PA------------------------------------------------------ ----------------------------------------------RRREQ--------- ------------------------------------------------------------ ----------------------------------------------------------EG SAP----------------------------HSPL-----LLLSSR-----HNNSVSQGT GAHRAQPPRSVT---------------------PSAEGQQQQPASTNPAAR--------- ------------------------------------------------------------ --------------EDAAA---------------------------TSRLWFQATRQRNA GDA---------------------AGRQRS-AGA-------------AQERRQGAQASHT --RVNG--TDR-------------VEGMQ-GDDPYN-PYKYSE-DNPYYNYYDTYERSR- ----T----NERQRPGY-GTRYFQNGLPDLVPDPYYIQASIYVQKMSMYNLRCAAEENCL ASSAYSSDVR----DYDQRVLLRFPQRVKNQGTADFLPSRPRYTWEWHSCHQHYHSMDEF SHYDLLDASSHRRVAEGHKASFCLEDTSCDYGYYRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYQVPESDYSNNVVRCDLRYTGHYVYTSGCTISPY- ------------------------------------------------------- >NP_996972.1 protein-lysine 6-oxidase precursor [Danio rerio] MSMSL-IDTFIYAF---------------------------------AHVCLLSC----- ----------------------------------------IAQTGQTQ-----RQGNT-- ------------GAAAL----------------------RQTIQWQHNGKLF-------- --SILSQGSEYQ------------------------------------------------ ----PP------------------------------------------------------ ----------------------------------------------LKRD---------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------GNKEQAQAR-PV-----AIVRND-------------D AATRTDSSAPS--------------------------RA--------SQSRGSV------ ------------------------------------------------------------ ------------RVPSGTG---A-------------------------RGGASRWLSGDG ART---------------------RGVHGR---------------------RNHTDPLRS -INGTDRPAGD-------------DEVMV-GDDPYN-PYKSTDPDNPYYNYYDTYERPR- ----P------AQRPGY-GTGYFQNGLPDLVGDPYYIQASTYVQRVPMYNLRCAAEENCL ASSAYRSSVR----DYDMRMLLRFPQRVKNQGTSDFLPSRPRYTWEWHSCHQHYHSMDEF SHYDLLDATTHRRVAEGHKASFCLEDTSCDYGYYRRYACT---SHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYQVPESDYSNNVVRCDVRYTGNYAYVSGCHISQY- ------------------------------------------------------- >XP_004074853.1 protein-lysine 6-oxidase [Oryzias latipes] MWLRQ-FGASRYAY---------------------------------ARICLFVL----- ----------------------------------------SLHTVHSQRNPGSQQRNE-- ------------QSAAL----------------------RQTLQWSHNGKVF-------- --SILSQGAEYQ------------------------------------------------ ----PA------------------------------------------------------ ----------------------------------------------RRR----------- ------------------------------------------------------------ ------------------------------------------------------------ GAP----------------------QEQVRAQ-QI-----TIVQDA-----D-----ERR QDTQQQSVARQ--------------------------DQ--------QPPRSV------- ------------------------------------------------------------ --------------PPQLQ-----------------------------RLVRGPEHRQQL QHE---------------------RFGE-------------------------RVNDTQK -VNVSSSLPRR-------------EDMMV-GDDPYD-PYKSIDGDNPYYNHYDVYERPR- ----E------RQRPGY-GTRYHQYGLPDLVPDPYYIQASAYVQRSPMYNLRCAAEENCL SSSAYRSSIR----DYDTRVLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHFHSMDEF SHYDLLDATSQRSVAEGHKASFCLEDTSCDYGYYRRYACT---SHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPYYQVPEQDYSNNIVRCDVRYTGNYAYVSGCHMSTY- ------------------------------------------------------- >XP_015796584.1 PREDICTED: protein-lysine 6-oxidase-like [Nothobranchius furzeri] MELRA-FCASRY-----------------------------------LRICLFVF----- ----------------------------------------LLQVSRCQRNPAARQRHE-- ------------EGAAL----------------------RQTLQWSHNGQVF-------- --SILSHGSEYE------------------------------------------------ ----PP------------------------------------------------------ ----------------------------------------------KRR----------- ------------------------------------------------------------ ------------------------------------------------------------ SAP----------------------QQQVQPR-PV-----TIIRDA-----E-------- -AVRPQDARSQQ-------------------------QQ--------QPPRSSI------ ------------------------------------------------------------ --------------PQPLQ-----------------------------RLVRGREHRQHL HRE---------------------RPGARA-G----------------TQESPRVNDAQG KVNVSR--PT--------------EDVML-GDDPYD-PYKSIDSDNPYYNYYDAYEQPR- ----P------RSRPGY-GTRYHQYGLPDLVPDPYYIQSSVYVQRVPMYSLRCAAEENCL SSSAYRS--R----DYDNRMLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHYHSMDEF SHYELLDATTHRAVAEGHKASFCLEDTSCDYGYYRRYACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGEYTLKISVNPYYQVPESDYSNNIVRCDVRYTGNYAHVSGCHMSTY- ------------------------------------------------------- >XP_030290565.1 protein-lysine 6-oxidase-like [Sparus aurata] MGLRI-FGTPLYAY---------------------------------ACVYFFVF----- ----------------------------------------ILQVAQSQRSPGTQQGEQ-- ------------QRAAL----------------------RQTLQWSHNGKIF-------- --SILSQGSEYQ------------------------------------------------ ----PP------------------------------------------------------ ----------------------------------------------RRR----------- ------------------------------------------------------------ ------------------------------------------------------------ GAP----------------------QEQVQAR-PV-----TIIRDA-----N-------- --VRPQDTSSQ--------------------------QQ--------QPPRPTSGAHSPG ------------------------------------------------------------ ------------GLPPPLQ-----------------------------RLVRGREHRQH- PRE---------------------RPGERA-----------------EPQRSSRANDTQD KVTVSPPLPRR-------------QDMMV-GDDPYNDPYKSMDGDNPYYNYYDVYERPR- ----P------RPRPGY-GTRDHQYGLPDLVPDAYYIQAAAYVQRVPMYNLRCAAEENCL SSSAYRSSVR----DYDTRMLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHFHSMDEF SHYELLDANTHHQMAEGHKASFCLEDTSCDYGYYRRFACT---AHTQGLSPGCFDTYNAD IDCQWIDITDVKPGSYILKVSVNPQYQVPESDYSNNIVRCDVRYDGNYAHVSGCHMSSY- ------------------------------------------------------- >KAF4017962.1 hypothetical protein G4228_009537 [Cervus hanglu yarkandensis] MAL------ALTGWQL----VWG------------------------ACVCVLVH----- ----------------------------------------------GQQAP--PGQGS-- ------------DPGRW----------------------RQLIQWENNGQVY-------- --SLLNSGAEYV------------------------------------------------ ----PP-G--------PQG------------------SEANSRVL--LAGAPQA------ -------------------------------------PPRRSQGGLRRRQAP-------- ------------------------------------------------------------ ----------------------------------------------------------SL PLPGR----------------VGSDTVRGQARHPFGFG--QVPDNW-----REVAVGDNT GMARARTSVSQQRHGGSASSVSASAFASTYRQPSSFPQQ--------QFPYPQAPFVSQY ETYDPATRTYDQGYVYYRSAG-GGLGAAAVASAGVVYPFQPRARYEEYGGGGGEEQPEYP PQGFYPAAPERPYAPQPAD---GLD-----------------------RRYSHSLYHEGT AGLEPAYPDPGPDAAQPNGGGGGGTYGGGG-GDHRLGWYPPYGNMPPEAYSPPRAVEPQP --------PFRV------------------LEPPYL-PVRSSD-APPPGSERNGAQQGR- ------LSVGSVYRPNQ-----NGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCL ASTAYGPEAT----DYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEF SHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACT---SHTQGLSPGCYDTYNAD IDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSTTNCKIVQ-- ------------------------------------------------------- >OWK10657.1 LOXL3 [Cervus elaphus hippelaphus] M-------RPVGVWRW---SLWG-------------------------LLLRLLC----- ----------------------SPCLGSPT-------PSGAPEKRAGSQGLRFRLAGFPR KPFEGRVEIQ--RAGEWGTICDDDFTLQAAHVLCRELGFTEATGWTHSA-KYGPGTGRIW LDNLSCSGTERSVTECASRGWGNSDCTHDEDAGVICKDERLPGFSDSNVIEVEHHLQVEE VRLRPAVGRGRRPLPVTEGLVEVRLPDGWSQVCDKGWTAHNSHVICGMLGFPSEKRVNVA FYRKLRKRAAKASARRSKPLGRPVTKLKAKPKTRMGRGPVKRLLARRQQHSF---GLHGV ACVGTEAHLSLCSLEFYRANDTTRCPGGAPAVVSCVPSPLYAASSGQKK----------- ----------------------------------------------------------QQ SKPQG------------------EARVRLKGGAHPGEGRVEVLKAG-----TWGTVCDRK WDLQAASVVCRELGFGSAREALSGAR---------MGQG--------MGAIHLSEVRCSG QELSLWKCPHKNITA---------EDCSHSQDAGVRC----------------------- ------------NLPYTGV---ET----------------------KV----SHSFHLG- -------------------------------SDD---W---------GTLEAMVACRQLG -LGYANH-GLQ-------------ETWYW-DSGNIT-EVVMSG-VRCTGTELSLDQCAHH ----GTHVTCKRTGSRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCL ASSARSA-----NWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIF THYDILTPNGT-KVAEGHKASFCLEDTECQEDVSKRYECA--NFGEQGITVGCWDLYRHD IDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAF SEEAN--------------------------RRFERYPGQTSNQVI--------- >NP_034858.2 protein-lysine 6-oxidase preproprotein [Mus musculus] M---------RFAWAV---LLLG-----------------------PLQLCPLLR----- ----------------------------------------CAP------QT-PREPPA-- ------------APGAW----------------------RQTIQWENNGQVF-------- --SLLSLGAQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------SA TARRP------------------DGDAASQPRTPI-----LLLRDN-----R-------T ASTRARTPSPS--------------------------GV--------AAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGFSPSG ARD---------------------GASRRA-A----------------NRTASPQPPQLS --NLRP--PSH-------------IDRMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GSRNRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCL ASSAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYAAD IDCQWIDITDVQPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >NP_058757.1 protein-lysine 6-oxidase precursor [Rattus norvegicus] M---------RFAWTV---LFLG-----------------------QLQFCPLLR----- ----------------------------------------CAP------QA-PREPPA-- ------------APGAW----------------------RQTIQWENNGQVF-------- --SLLSLGAQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDS--------- ------------------------------------------------------------ ----------------------------------------------------------SA TAPRA------------------DGNAAAQPRTPI-----LLLRDN-----R-------T ASARARTPSPS--------------------------GV--------AAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQVGFSPSG AGD---------------------GASRRA-A----------------NRTASPQPPQLS --NLRP--PSH-------------VDRMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----S----GSRHRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCL ASSAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYAAD IDCQWIDITDVQPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >NP_776357.2 protein-lysine 6-oxidase precursor [Bos taurus] M---------RFAWTA----LLG-----------------------SLQLCALVR----- ----------------------------------------CAPPAASHRQP-PREQAA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA TAPGA------------------ANATAPQMRTPI-----LLLRNN-----R-------T AAARVRTAGPS--------------------------AA--------AAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSTSG AHD---------------------AGTSRA-D----------------NQTAPGEVPTLS --NLRP--PNRVD-----------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCL ASSAYRGDVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >NP_990812.2 protein-lysine 6-oxidase precursor [Gallus gallus] M---------RCAPPG---LLLA-----------------------QLHACIFWS----- ----------------------------------------GLWPAGCQ---------S-- ------------PPAAW----------------------RQRIQWENNGQVY-------- --SLLSQGAQYQ------------------------------------------------ ----PP------------------------------------------------------ ----------------------------------------------RRRQ---------- ------------------------------------------------------------ ------------------------------------------------------------ ---GA------------------EPA-----SSPV-----LLLRGN-----G--SVPR-A AAAAAARPQPE--------------------------PQ--------PQAQ--------- ------------------------------------------------------------ --------------PQPRPRSS-RRQP------------------LGRRHWFQAGYRAPS GSAR-------------------PAPRRRP-RGRR--------SR-RRERAERRRAAAPS --GLR---PGR-------------EDVMV-GDDPYS-PYKYTD-DNPYYNYYDTYERPR- ----Q----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQRMSMYNLRCAAEENCL ASSAYRADVR----DYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDIRYTGHHAYASGCTISP-- ------------------------------------------------------- >XP_001153015.1 protein-lysine 6-oxidase [Pan troglodytes] M---------RFAWTV---LLLG-----------------------PLQLCALVH----- ----------------------------------------CAPPAAGQQQP-PREPPA-- ------------APGAW----------------------RQQIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA AVPGA------------------ANASAQQPRTPI-----LLIRDN-----R-------T AAARARTAGSS--------------------------GV--------TAGR--------- ------------------------------------------------------------ --------------PRPTA-----------------------------RHWFQAGYSTTR ARE---------------------AGASRA-E----------------NQTAPGDVPALS --NLQP--PSR-------------VDGMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GGRYRPGY-GTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYGAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_005626496.1 protein-lysine 6-oxidase isoform X1 [Canis lupus familiaris] M---------RFAWTA---LLLG-----------------------PLQLCALLR----- ----------------------------------------CAPPAAGQQQP-PRQPPA-- ------------APAAW----------------------RQRIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GT TAPGA------------------ANAAAPQPRTPI-----LLLR-N-----R-------T AAARERAAGTA--------------------------G---------GAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSASG ARD---------------------A-----------------------NQTAPGERPALS --NLRP--PSR-------------VDGMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCL ASSAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_008253171.1 PREDICTED: protein-lysine 6-oxidase isoform X1 [Oryctolagus cuniculus] M---------LCSWTV---LLLG-----------------------PLQLCALVC----- ----------------------------------------GAPQAAGQQQP-PREPPA-- ------------APGAW----------------------RQRIQWENNGQVF-------- --SLLSLGAQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDA--------- ------------------------------------------------------------ ----------------------------------------------------------GA AAPGA------------------QRAAGPQQRTPV-----LLLRDN-----R-------T AA----------------------------------------------ASR--------- ------------------------------------------------------------ --------------PRPAG-----------------------------RHWFQAGYASPG ARD---------------------AGASRA-G----------------NRTAQGEPPALS --NLRP--PSH-------------VDRMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCL ASSAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYAAD IDCQWIDITDVQPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_009239271.1 protein-lysine 6-oxidase [Pongo abelii] M---------RFAWTV---LLLG-----------------------PLQLCALVH----- ----------------------------------------CAPPAAGQQQP-QREPPA-- ------------APGAW----------------------RQQIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA AVPGA------------------ANASAQQPRTPI-----LLIRDN-----R-------T AAARARTAGSS--------------------------GV--------TAGR--------- ------------------------------------------------------------ --------------PRPTA-----------------------------RHWFQAGYSTST ARE---------------------AGASRA-E----------------NQTALGDVPALS --NLQP--PSR-------------VDGMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GGRYRPGY-GTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYGAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >NP_001193332.1 protein-lysine 6-oxidase precursor [Sus scrofa] M---------RFAWTS---LLLG-----------------------LLQLCAPVR----- ----------------------------------------CAPPATGQQQP-PREPPA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA TAPGA------------------ANATTPQLRTPI-----LLLRNN-----R-------T AAARARTALSS--------------------------GA--------VAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSTSG ARD---------------------AGASSA-G----------------NQTAPGELPALS --NLQP--PSRVD-----------VDGMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_003826749.1 protein-lysine 6-oxidase [Pan paniscus] M---------RFAWTV---LLLG-----------------------PLQLCALVH----- ----------------------------------------CAPPAAGQQQP-PREPPA-- ------------APGAW----------------------RQQIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA AVPGA------------------ANASAQQPRTPI-----LLIRDN-----R-------T AAARARTAGSS--------------------------GV--------TAGR--------- ------------------------------------------------------------ --------------PRPTA-----------------------------RHWFQAGYSTTR ARE---------------------AGASRA-E----------------NQTAPGDVPALS --NLQP--PSR-------------VDGMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GGRYRPGY-GTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYGAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_023110382.1 protein-lysine 6-oxidase isoform X1 [Felis catus] M---------RFAWTA---LVLG-----------------------PLQLCALLR----- ----------------------------------------CAQPAAGQQQP-PRQPPA-- ------------APAAW----------------------RQRIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA TAPGA------------------ANAAVPQPRTPI-----LLLR-N-----R-------T AAARERTPGSS--------------------------G---------ATGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSPSG ARD---------------------AGDSRD-G----------------NGTEPGERPALS --NLRP--PSR-------------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCL ASSAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_027825796.1 protein-lysine 6-oxidase isoform X1 [Ovis aries] M---------RFAWTA----LLG-----------------------SLQLCALVR----- ----------------------------------------CAPPAASHRQP-PREQAA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA TAPGA------------------ANATAPQMRTPI-----LLLRNN-----R-------T AAARVRTAGPS--------------------------AA--------AAGR--------- ------------------------------------------------------------ --------------PRPVA-----------------------------RHWFQAGYSTSG AHE---------------------AGTSRA-D----------------NQTAPGEVPTLS --NLRP--PNRVD-----------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCL ASSAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_004042452.3 protein-lysine 6-oxidase [Gorilla gorilla gorilla] M---------RFAWTV---LLLG-----------------------PLQLCALVH----- ----------------------------------------CAPPAAGQQQP-PREPPA-- ------------APGAW----------------------RQQIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA AVPGA------------------ANASAQQPRTPI-----LLIRDN-----R-------T AAARARTAGSS--------------------------GV--------TAGR--------- ------------------------------------------------------------ --------------PRPTA-----------------------------RHWFQAGYSTSR ARE---------------------AGASRA-E----------------NQTAPGDVPALS --NLQP--PSR-------------VDGMV-GDDPYN-PYKYSD-DNPYYNYYDTYERPR- ----P----GGRYRPGY-GTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYGAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_005506283.1 protein-lysine 6-oxidase isoform X1 [Columba livia] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MSMYNLRCAAEENCL ASSAYRADVR----DYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_005682773.2 PREDICTED: protein-lysine 6-oxidase isoform X1 [Capra hircus] M---------RFAWTA----LLG-----------------------SLQLCALVR----- ----------------------------------------CAPPAASHRQP-PREQAA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------GA TAPGA------------------ANATAPQMRTPI-----LLLRNN-----R-------T AAARVRTAGPS--------------------------AA--------AAGR--------- ------------------------------------------------------------ --------------PRPVA-----------------------------RHWFQAGYSTSG ANE---------------------AGTSRA-D----------------NQTAPGEVPTLS --NLRP--PNRVD-----------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCL ASSAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_025066263.1 protein-lysine 6-oxidase isoform X1 [Alligator sinensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MSMYNLRCAAEENCL ASSAYRSDVR----DYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANSYRKVAEGHKASFCLEDTSCDYGYYRRYACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCDIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_019333711.1 PREDICTED: LOW QUALITY PROTEIN: protein-lysine 6-oxidase [Alligator mississippiensis] M---------RPAPAAA-VALLA-----------------------QLHVCLYLG----- ----------------------------------------CA----GQ----PRRAPP-- ------------PPAAW----------------------RQRIQWENNGQVF-------- --SLLSLGARYQ------------------------------------------------ ----PA------------------------------------------------------ ----------------------------------------------RR------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GA------------------APAAA---ASPV-----LLLRNN-----R-------T AXXXXXXXXXXX------------------------------------------------ ------------------------------------------------------------ --------------XXXXXXXX-XXXX------------------XXXXXXXXXXXXAPA -----------------------PTPAR-----------------------------APS --APR---PGR-------------EDIMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----Q----GSSYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQRMSMYNLRCAAEENCL ASSAYRSDVR----DYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDANSYRKVAEGHKASFCLEDTSCDYGYYRRYACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCDIRYTGHHAYASGCTISP-- ------------------------------------------------------- >XP_019466272.1 protein-lysine 6-oxidase [Meleagris gallopavo] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MDEF SHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVRS-------------------------------------- ------------------------------------------------------- >XP_020754628.1 protein-lysine 6-oxidase isoform X1 [Odocoileus virginianus texanus] M---------RFAWTA----LLG-----------------------SLQLCALVR----- ----------------------------------------CAPPAASHRQP-PREQAA-- ------------APGAW----------------------RQKIQWENNGQVF-------- --SLLSLGSQYQ------------------------------------------------ ----PQ------------------------------------------------------ ----------------------------------------------RRRDP--------- ------------------------------------------------------------ ----------------------------------------------------------SA TAPGA------------------ANATAPQMRTPI-----LLLRNN-----R-------T AAARVRTAGPS------------------------AAAA--------AAGR--------- ------------------------------------------------------------ --------------PRPAA-----------------------------RHWFQAGYSTSG AQD---------------------AGTSRA-D----------------NQTAPGEVPTLS --NLRP--PNRVD-----------VDGMV-GDDPYN-PYKYTD-DNPYYNYYDTYERPR- ----P----GSRYRPGY-GTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCL ASTAYRADVR----DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY- ------------------------------------------------------- >XP_040200086.1 protein-lysine 6-oxidase isoform X1 [Rana temporaria] MGC---TKGSVF----------------------------------LLQLAVYFY----- ----------------------------------------CILQGSCQS---YRSQSS-- ------------HSAFW----------------------KHRVQWQNSGRVY-------- --NLLSQGSEYK------------------------------------------------ ----PP------------------------------------------------------ ----------------------------------------------RRRES--------- ------------------------------------------------------------ ----------------------------------------------------------VE STPSRS-----------------ILLLSAKNHTSI-----SLSEPG-----R-------P QSSNPGNNQTP--------------------------GL--------ERSN--------- ------------------------------------------------------------ --------------PQRLR-----------------------------DSSGQLSVQASR ARS---------------------RAGDAT-GQQR--------TREDAIRARHQSTPRPS --NRQQ--PQTVNATAVNSIRQDVAQGLQ-GDDPYN-PYKYSE-DNRYQNQFDTYERRR- ----E----SLRRRPGN-GMQYIQHGLPDLVPDPYYIQSSIYVQKMSMYSLRCAAEENCL ASSAYRSDVR----DYDQRVLLRFPQRVKNQGTADFLPSRPRYSWEWHSCHQHYHSMDEF SHYDLLDASSQRRVAEGHKASFCLEDTSCDYGYYRRFACT---AHTQGLSPGCYDTYNAD IDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDVRYTGQHVYTSSCTISPY- -------------------------------------------------------
BMGE Cleaned alignment of selected proteins >NP_002308.2 protein-lysine 6-oxidase isoform 1 preproprotein [Homo sapiens] PLQLCALVHCAPPAAGQQQPAPGAWRQQIQWENNGQVFSLLSLGSQYQRRRDPGAAVPGAQQPRTPILLIRDNTAAARTRHWFQAGAGASRATAPGEVPALSVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_039262610.1 lysyl oxidase homolog 3A-like isoform X2 [Styela clava] --SSFFFVMSELQTKAEEKIHDGEWEGALDFAHSG-KYNVHCDGEEKSQKHRNIRNQKGGLKSGSTVEVMRNGYFDIRDRIVGGRNKWGPICEAMVACRQLGEVWYYGSDDASSLMMTGVECKGDEIGIQYCHHSKRTMTPFAGVICTEGSPDLITDIPMLSDSIHMEDRGLSNLICAAEEKCLSSSADELDMRSYGHRRLLRFSSRVWNRGRADFRPARLPNDWEWHSCHGHFHSMAEFTHYDILSLNKT-RVAEGHKASFCLEDTHCDDGVSRRYDCDGGTQGITVGCSDTYLYNIDCQWIDITDLPGGNYLFRVHVNPNHLVPESDFSNNEVICNMRYDGQQVWVWNCHIGTD >NP_001073015.1 lysyl oxidase-like 2 precursor [Strongylocentrotus purpuratus] EPTTIAATTGEPTTRPPAKIHGGSWKKAVQYFFGSSQFEVECLGTEKNQRKKSPYSPPWSLKAGAAFEVFHAGDFDKVARLVQGRFQWGHPCDAKVACRQLGSTRFMGRSGY-PILMLDVNCTGNERTLSECPHNGTCMADYAGILCAGVLPDVLMDVHVLQSSIYMQDWPMYMLQCAAEENCLSSESH-----VRGARRLLRFASAIMNRGTEEFRPVLGRSSWEWHACHRHYHSMDVFSTYDLLDADGV-RVAEGHKASFCLEDVYCDSGAQKVYSC-AGTQGISVNCVDIYRNDIDCQWIDVTGVPQGSYVLRVDVNPNHIVGETDFTNNEVLCDVMLT-YRVRIQNCRYADD >CAE1283062.1 LOXL2_3_4 [Sepia pharaonis] --LPSTTTA-----------------------------DIQKTTLAIRRNKTSNRSQPEILNANNNLEILKDEVGSLPATLNGGRYKWGVVCEASVVCRQLGINYY-GGSHL-PKLFARIRCHGNESHLADCERVKCSKDVSAGVICTNVLPDLIPDALALQKSVRLEDRPLYYLTCSMEENCLADEAYEIKERITASRRLLRFSSIVYNIGTADFIPNSPKDAWEWHQCHMHYHSMEVFAHYDILDLQGN-RIAQGHKASFCLEDTRCPPGITPKYNCLFGDQGLSVNCSDNYYHDIDCQWIDITGIKFGNYILKVEFNPEMYVSEITFDNNVVECSLYYTGTYAYLRKCDIVPL >XP_016772223.2 lysyl oxidase homolog 4 isoform X3 [Apis mellifera] FSIILAIMV-----------------------------DVRTTANSNDEKKARKLKKQEGLVGGEN-------------RLAGGRVDWGVICEAAVVCRQLGTNFF-GGEKT-PMAISGVQCRGNESSLTDCLHCPGPVENVGSVVCLRDMPDLVFDHIELMRTAHLEDRQLYWLQCAMEENCVASQAYKIQKEHLETRRLLRFTARILNAGTADFRPSVPKHLWEWHMCHMHYHSMEVFATFDVLDLNGT-RLAEGHKASFCLEDNQCLPGVEARYKCAYGDQGISVNCSDIYRHNIDCQWVDISELRPGEYIFKVGVNPELKVGEMSFDNNAAICRLLYTESFATVHSCVMGRP >XP_038065185.1 lysyl oxidase homolog 2A-like isoform X2 [Patiria miniata] --SAIALISGGVKGDAPKPARQRAYAEAMDFHFGN-VFDVRCTGNETHQRRKSAKRRKGKLKSGAYYEVYVNGGWDEVSRIEGGTYEWGNICAGKVVCRQLGSTLSYGSAPKRTFLMMEVKCTGHERTIKECKYANTCIRAFAGVVCVDTLPDVLMDLHVLQSSVRVQDWPDTLLTCAREEGCLSDVPN-----NWGLRRLLRFTSAIMNRGMEQFRPLLSRYSWKWHLCHRHFHSMEVFSHYDLINQKGE-RVAQGHKASFCLEDGHCDEGITPQFSCI-TDQGISVNCIDIYASNIDCQWVDVTGVKTDLYTLRIHINPDNLVAESDYDNNLIECDLYY-GRRITIGHCEYVTD >CAB99481.1 lysyl oxidase-like 2 [Drosophila melanogaster] LTLVCLTLL-----------------------------AIHMADAVVQQERQRVLNKEEGLVGGDNEEVLHNGEWDSTERLRGGRSRWGSVCEANVVCRQLGTDFF-GGFNVSRPVLSGSECYGNETELADCLHCHGNRQHVAAVICDYIAPDLVVDYLEIEQTAHLEDRPMLLMQCAMEENCVANEAYQIQRDRYRSRRLLKFTAAAINAGNADFRPFKEKSQWEWHMCHMHFHSMEVFATFDIFNLRGI-KVAQGHKASFCLEDSNCLPGVAKKYNCASGDQGISINCSDVYLYNLDCQWVDVTDLIPGTYVLKIAINPEFKVAEMNYDNNAAICDLIYTANFARVQNCQLGRP >XP_031556434.1 lysyl oxidase homolog 2A-like [Actinia tenebrosa] --ILSLFIC----SSVARRLHNDKWPDALRYTSGD-WFDVQCNGDEWTEKDLP-------LRGSFNLEVRNPNHFGLKDRIAGGMTRWGAVCEAVVACRHLGSNYF-GVTSL-PVIFSNVDCKLDEISLHHCERITRCRSGRAGIICTRAVPDLVVNVDELEKNVRIDAIPLAYMQCSYEENCLGESAREQWPNRYYTRRLLRFTTRVENRGLAPFKPDVPKSSWQWHQCHNHYHSMEVFSTYDLVDFSGI-KAAAGHKASFCLEDTVCDEGIPKTFNCTGGDQGISPNCYDVYKWNIDCQWIDVTDFPHGSFYLRVTVNPDRKVAESDYLNNIAKCELYDYGNFAVAAKCHLEEC >KAB0387850.1 hypothetical protein FD755_002806 [Muntiacus reevesi] SLQLCALVRCAPPAASHRQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDSGATAPGAPQMRTPILLLRNNTAAARVRHWFQAGAGTSRATAPGEVPTLSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPL >KAB0358923.1 hypothetical protein FD754_003079 [Muntiacus muntjak] SLQLCALVRCAPPAASHRQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDSGATAPGAPQMRTPILLLRNNTAAARVRHWFQAGAGTSRATAPGEVPTLSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPL >XP_043321819.1 protein-lysine 6-oxidase isoform X1 [Cervus canadensis] SLQLCALVRCAPPAAGHRQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDPGAAAPGAPQMRTPILLLRNNTAAARARHWFQAGAGTSRATAPGEVPTLSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >NP_001089167.1 lysyl oxidase L homeolog precursor [Xenopus laevis] -LQLVLYLHCLLLGDCQQQ-PSSMWRQRLQWQSNGRVYSLLSHGSEYQRRREQEGSAP-----HSPLLLLSSRTGAHRARLWFQATAGRQRSRRQGAQASHTVEGMQGDDPYNPYKYSEDNPYYNYYDTYERSRNERQRPGYGTRYFQNGLPDLVPDPYYIQASIYVQKMSMYNLRCAAEENCLASSAYSSDVRDYDQRVLLRFPQRVKNQGTADFLPSRPRYTWEWHSCHQHYHSMDEFSHYDLLDASSHRRVAEGHKASFCLEDTSCDYGYYRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYQVPESDYSNNVVRCDLRYTGHYVYTSGCTISPY >NP_996972.1 protein-lysine 6-oxidase precursor [Danio rerio] -AHVCLLSCIAQTGQTQ---GAAALRQTIQWQHNGKLFSILSQGSEYQLKRD--------AQAR-PVAIVRNDDAATRTRGGASRWRGVHGR-RNHTDPLRSDEVMVGDDPYNPYKSTDDNPYYNYYDTYERPR--AQRPGYGTGYFQNGLPDLVGDPYYIQASTYVQRVPMYNLRCAAEENCLASSAYRSSVRDYDMRMLLRFPQRVKNQGTSDFLPSRPRYTWEWHSCHQHYHSMDEFSHYDLLDATTHRRVAEGHKASFCLEDTSCDYGYYRRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYQVPESDYSNNVVRCDVRYTGNYAYVSGCHISQY >XP_004074853.1 protein-lysine 6-oxidase [Oryzias latipes] -ARICLFVLSLHTVHSQRNPQSAALRQTLQWSHNGKVFSILSQGAEYQRRR----GAP--VRAQ-QITIVQDARQDTQQRLVRGPERFGE-----RVNDTQKEDMMVGDDPYDPYKSIDDNPYYNHYDVYERPR--RQRPGYGTRYHQYGLPDLVPDPYYIQASAYVQRSPMYNLRCAAEENCLSSSAYRSSIRDYDTRVLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHFHSMDEFSHYDLLDATSQRSVAEGHKASFCLEDTSCDYGYYRRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPYYQVPEQDYSNNIVRCDVRYTGNYAYVSGCHMSTY >XP_015796584.1 PREDICTED: protein-lysine 6-oxidase-like [Nothobranchius furzeri] -LRICLFVFLLQVSRCQRNPEGAALRQTLQWSHNGQVFSILSHGSEYEKRR----SAP--VQPR-PVTIIRDA--AVRPRLVRGRERPGARAESPRVNDAQGEDVMLGDDPYDPYKSIDDNPYYNYYDAYEQPR--RSRPGYGTRYHQYGLPDLVPDPYYIQSSVYVQRVPMYSLRCAAEENCLSSSAYRS--RDYDNRMLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHYHSMDEFSHYELLDATTHRAVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGEYTLKISVNPYYQVPESDYSNNIVRCDVRYTGNYAHVSGCHMSTY >XP_030290565.1 protein-lysine 6-oxidase-like [Sparus aurata] -ACVYFFVFILQVAQSQRSPQRAALRQTLQWSHNGKIFSILSQGSEYQRRR----GAP--VQAR-PVTIIRDA---VRPRLVRGRERPGERARSSRANDTQDQDMMVGDDPYNPYKSMDDNPYYNYYDVYERPR--RPRPGYGTRDHQYGLPDLVPDAYYIQAAAYVQRVPMYNLRCAAEENCLSSSAYRSSVRDYDTRMLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQHFHSMDEFSHYELLDANTHHQMAEGHKASFCLEDTSCDYGYYRRFACTAHTQGLSPGCFDTYNADIDCQWIDITDVKPGSYILKVSVNPQYQVPESDYSNNIVRCDVRYDGNYAHVSGCHMSSY >KAF4017962.1 hypothetical protein G4228_009537 [Cervus hanglu yarkandensis] -ACVCVLVH------GQQAPDPGRWRQLIQWENNGQVYSLLNSGAEYVRRRQASLPLPGRGQARHPFQVPDNWTGMARARRYSHSLTYGGGGSPPRAVEPQP-----LEPPYLPVRSSDAPPPGSERNGAQQGRGSVYRPNQ----NGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYGPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSTTNCKIVQ- >OWK10657.1 LOXL3 [Cervus elaphus hippelaphus] --LLLRLLCAPEKRAGSQGLRAGEWTEATGWTHSA-KYNLSCSGTERSRQQHSQQSKPQGLKGGAHPEVLKAGKWDLQA----SHS------EAMVACRQLGETWYWDSGNITEVVMSGVRCTGTELSLDQCAHCKRTGSRFAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSA---PYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGT-KVAEGHKASFCLEDTECQEDVSKRYECAFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDA >NP_034858.2 protein-lysine 6-oxidase preproprotein [Mus musculus] PLQLCPLLRCAP------QTAPGAWRQTIQWENNGQVFSLLSLGAQYQRRRDPSATARRPSQPRTPILLLRDNTASTRARHWFQAGGASRRATASPQPPQLSIDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRGSRNRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYAADIDCQWIDITDVQPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >NP_058757.1 protein-lysine 6-oxidase precursor [Rattus norvegicus] QLQFCPLLRCAP------QAAPGAWRQTIQWENNGQVFSLLSLGAQYQRRRDSSATAPRAAQPRTPILLLRDNTASARARHWFQVGGASRRATASPQPPQLSVDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRGSRHRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYAADIDCQWIDITDVQPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >NP_776357.2 protein-lysine 6-oxidase precursor [Bos taurus] SLQLCALVRCAPPAASHRQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDPGATAPGAPQMRTPILLLRNNTAAARVRHWFQAGAGTSRATAPGEVPTLSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRGDVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >NP_990812.2 protein-lysine 6-oxidase precursor [Gallus gallus] QLHACIFWSGLWPAGCQ---PPAAWRQRIQWENNGQVYSLLSQGAQYQRRRQ------GA---SSPVLLLRGNAAAAAARHWFQAGAPRRRPAERRRAAAPSEDVMVGDDPYSPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQRMSMYNLRCAAEENCLASSAYRADVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDIRYTGHHAYASGCTISP- >XP_001153015.1 protein-lysine 6-oxidase [Pan troglodytes] PLQLCALVHCAPPAAGQQQPAPGAWRQQIQWENNGQVFSLLSLGSQYQRRRDPGAAVPGAQQPRTPILLIRDNTAAARARHWFQAGAGASRATAPGDVPALSVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_005626496.1 protein-lysine 6-oxidase isoform X1 [Canis lupus familiaris] PLQLCALLRCAPPAAGQQQPAPAAWRQRIQWENNGQVFSLLSLGSQYQRRRDPGTTAPGAPQPRTPILLLR-NTAAARERHWFQAGA-----TAPGERPALSVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_008253171.1 PREDICTED: protein-lysine 6-oxidase isoform X1 [Oryctolagus cuniculus] PLQLCALVCGAPQAAGQQQPAPGAWRQRIQWENNGQVFSLLSLGAQYQRRRDAGAAAPGAPQQRTPVLLLRDNTAA---RHWFQAGAGASRATAQGEPPALSVDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYAADIDCQWIDITDVQPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_009239271.1 protein-lysine 6-oxidase [Pongo abelii] PLQLCALVHCAPPAAGQQQPAPGAWRQQIQWENNGQVFSLLSLGSQYQRRRDPGAAVPGAQQPRTPILLIRDNTAAARARHWFQAGAGASRATALGDVPALSVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >NP_001193332.1 protein-lysine 6-oxidase precursor [Sus scrofa] LLQLCAPVRCAPPATGQQQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDPGATAPGAPQLRTPILLLRNNTAAARARHWFQAGAGASSATAPGELPALSVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_003826749.1 protein-lysine 6-oxidase [Pan paniscus] PLQLCALVHCAPPAAGQQQPAPGAWRQQIQWENNGQVFSLLSLGSQYQRRRDPGAAVPGAQQPRTPILLIRDNTAAARARHWFQAGAGASRATAPGDVPALSVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_023110382.1 protein-lysine 6-oxidase isoform X1 [Felis catus] PLQLCALLRCAQPAAGQQQPAPAAWRQRIQWENNGQVFSLLSLGSQYQRRRDPGATAPGAPQPRTPILLLR-NTAAARERHWFQAGAGDSRDTEPGERPALSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_027825796.1 protein-lysine 6-oxidase isoform X1 [Ovis aries] SLQLCALVRCAPPAASHRQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDPGATAPGAPQMRTPILLLRNNTAAARVRHWFQAGAGTSRATAPGEVPTLSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_004042452.3 protein-lysine 6-oxidase [Gorilla gorilla gorilla] PLQLCALVHCAPPAAGQQQPAPGAWRQQIQWENNGQVFSLLSLGSQYQRRRDPGAAVPGAQQPRTPILLIRDNTAAARARHWFQAGAGASRATAPGDVPALSVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY >XP_005506283.1 protein-lysine 6-oxidase isoform X1 [Columba livia] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSMYNLRCAAEENCLASSAYRADVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDIRYTGHHAYASGCTISPY >XP_005682773.2 PREDICTED: protein-lysine 6-oxidase isoform X1 [Capra hircus] SLQLCALVRCAPPAASHRQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDPGATAPGAPQMRTPILLLRNNTAAARVRHWFQAGAGTSRATAPGEVPTLSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_025066263.1 protein-lysine 6-oxidase isoform X1 [Alligator sinensis] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSMYNLRCAAEENCLASSAYRSDVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANSYRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCDIRYTGHHAYASGCTISPY >XP_019333711.1 PREDICTED: LOW QUALITY PROTEIN: protein-lysine 6-oxidase [Alligator mississippiensis] QLHVCLYLGCA----GQ---PPAAWRQRIQWENNGQVFSLLSLGARYQRR--------GA---ASPVLLLRNNTAXXXXXXXXXXXTPAR---------APSEDIMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSSYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQRMSMYNLRCAAEENCLASSAYRSDVRDYDNRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANSYRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCDIRYTGHHAYASGCTISP- >XP_019466272.1 protein-lysine 6-oxidase [Meleagris gallopavo] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEFSHYDLLDASSHRKVAEGHKASFCLEDTSCDYGYYRRYACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVRS------------------------------------- >XP_020754628.1 protein-lysine 6-oxidase isoform X1 [Odocoileus virginianus texanus] SLQLCALVRCAPPAASHRQPAPGAWRQKIQWENNGQVFSLLSLGSQYQRRRDPSATAPGAPQMRTPILLLRNNTAAARVRHWFQAGAGTSRATAPGEVPTLSVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY >XP_040200086.1 protein-lysine 6-oxidase isoform X1 [Rana temporaria] LLQLAVYFYCILQGSCQS--HSAFWKHRVQWQNSGRVYNLLSQGSEYKRRRESVESTPSRAKNHTSISLSEPGPQSSNPDSSGQLSRAGDATARHQSTPRPSAQGLQGDDPYNPYKYSEDNRYQNQFDTYERRRSLRRRPGNGMQYIQHGLPDLVPDPYYIQSSIYVQKMSMYSLRCAAEENCLASSAYRSDVRDYDQRVLLRFPQRVKNQGTADFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASSQRRVAEGHKASFCLEDTSCDYGYYRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNIVRCDVRYTGQHVYTSSCTISPY
PhyML tree of selected proteins (XP_005506283_1_protein_lysine_6_oxidase_isoform_X1__Columba_livia_:0.00000001,((XP_025066263_1_protein_lysine_6_oxidase_isoform_X1__Alligator_sinensis_:0.00000001,XP_019333711_1_PREDICTED__LOW_QUALITY_PROTEIN__protein_lysine_6_oxidase__Alligator_mississippiensis_:0.00000001):0.03593514,((KAF4017962_1_hypothetical_protein_G4228_009537__Cervus_hanglu_yarkandensis_:0.69077084,(NP_996972_1_protein_lysine_6_oxidase_precursor__Danio_rerio_:0.13140732,((XP_004074853_1_protein_lysine_6_oxidase__Oryzias_latipes_:0.05658295,(XP_031556434_1_lysyl_oxidase_homolog_2A_like__Actinia_tenebrosa_:0.90395505,((CAE1283062_1_LOXL2_3_4__Sepia_pharaonis_:0.76214205,(XP_016772223_2_lysyl_oxidase_homolog_4_isoform_X3__Apis_mellifera_:0.40825979,CAB99481_1_lysyl_oxidase_like_2__Drosophila_melanogaster_:0.51541128):0.3108933):0.32829953,((XP_039262610_1_lysyl_oxidase_homolog_3A_like_isoform_X2__Styela_clava_:0.53890827,OWK10657_1_LOXL3__Cervus_elaphus_hippelaphus_:0.55899414):0.19641395,(NP_001073015_1_lysyl_oxidase_like_2_precursor__Strongylocentrotus_purpuratus_:0.42344789,XP_038065185_1_lysyl_oxidase_homolog_2A_like_isoform_X2__Patiria_miniata_:0.74807086):0.45110269):0.12590386):0.06170114):1.40101685):0.0521124,(XP_030290565_1_protein_lysine_6_oxidase_like__Sparus_aurata_:0.09661434,XP_015796584_1_PREDICTED__protein_lysine_6_oxidase_like__Nothobranchius_furzeri_:0.10668773):0.01601623):0.15880975):0.13189086):0.07653139,((XP_023110382_1_protein_lysine_6_oxidase_isoform_X1__Felis_catus_:0.00677902,(XP_005626496_1_protein_lysine_6_oxidase_isoform_X1__Canis_lupus_familiaris_:0.00326482,(((XP_008253171_1_PREDICTED__protein_lysine_6_oxidase_isoform_X1__Oryctolagus_cuniculus_:0.0215993,(NP_034858_2_protein_lysine_6_oxidase_preproprotein__Mus_musculus_:0.01899535,NP_058757_1_protein_lysine_6_oxidase_precursor__Rattus_norvegicus_:0.02677014):0.05926569):0.02165067,(NP_002308_2_protein_lysine_6_oxidase_isoform_1_preproprotein__Homo_sapiens_:0.00314176,((XP_003826749_1_protein_lysine_6_oxidase__Pan_paniscus_:0.00000001,(XP_001153015_1_protein_lysine_6_oxidase__Pan_troglodytes_:0.00000001,XP_004042452_3_protein_lysine_6_oxidase__Gorilla_gorilla_gorilla_:0.00000001):0.00000001):0.00000001,XP_009239271_1_protein_lysine_6_oxidase__Pongo_abelii_:0.00311305):0.00309493):0.02601453):0.01724027,(NP_001193332_1_protein_lysine_6_oxidase_precursor__Sus_scrofa_:0.01649832,(XP_043321819_1_protein_lysine_6_oxidase_isoform_X1__Cervus_canadensis_:0.0030768,((NP_776357_2_protein_lysine_6_oxidase_precursor__Bos_taurus_:0.00306131,(XP_027825796_1_protein_lysine_6_oxidase_isoform_X1__Ovis_aries_:0.00000001,XP_005682773_2_PREDICTED__protein_lysine_6_oxidase_isoform_X1__Capra_hircus_:0.00000001):0.00000001):0.00305676,(XP_020754628_1_protein_lysine_6_oxidase_isoform_X1__Odocoileus_virginianus_texanus_:0.00305423,(KAB0387850_1_hypothetical_protein_FD755_002806__Muntiacus_reevesi_:0.00000001,KAB0358923_1_hypothetical_protein_FD754_003079__Muntiacus_muntjak_:0.00000001):0.00617075):0.00000001):0.00619045):0.024175):0.00787723):0.01564061):0.00897964):0.07105135,(NP_001089167_1_lysyl_oxidase_L_homeolog_precursor__Xenopus_laevis_:0.09640808,XP_040200086_1_protein_lysine_6_oxidase_isoform_X1__Rana_temporaria_:0.28665778):0.16415923):0.04130754):0.02558695):0.07375147,(XP_019466272_1_protein_lysine_6_oxidase__Meleagris_gallopavo_:0.05151454,NP_990812_2_protein_lysine_6_oxidase_precursor__Gallus_gallus_:0.00000001):0.00000001);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)